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Volumn 21, Issue 2, 2003, Pages 85-90

Genetics of inflammatory bowel diseases - Past, present, and future

Author keywords

Candidate gene approach; Crohn's disease; Genetic epidemiology; Genetics; Genome wide screening; Inflammatory bowel disease; Ulcerative colitis

Indexed keywords

IMMUNOMODULATING AGENT;

EID: 0142249902     PISSN: 02572753     EISSN: None     Source Type: Journal    
DOI: 10.1159/000073241     Document Type: Review
Times cited : (7)

References (39)
  • 2
    • 0033112962 scopus 로고    scopus 로고
    • Is antibody testing for inflammatory bowel disease clinically useful?
    • Panaccione R, Sandborn WJ: Is antibody testing for inflammatory bowel disease clinically useful? Gastroenterology 1999;116:1001-1002.
    • (1999) Gastroenterology , vol.116 , pp. 1001-1002
    • Panaccione, R.1    Sandborn, W.J.2
  • 3
    • 0033805362 scopus 로고    scopus 로고
    • Marker antibody expression stratifies Crohn's disease into immunologically homogeneous subgroups with distinct clinical characteristics
    • Vasiliauskas EA, Kam LY, Karp LC, Gaiennie J, Yang H, Targan SR: Marker antibody expression stratifies Crohn's disease into immunologically homogeneous subgroups with distinct clinical characteristics. Gut 2000;47:487-496.
    • (2000) Gut , vol.47 , pp. 487-496
    • Vasiliauskas, E.A.1    Kam, L.Y.2    Karp, L.C.3    Gaiennie, J.4    Yang, H.5    Targan, S.R.6
  • 4
    • 0036180967 scopus 로고    scopus 로고
    • Antineutrophil cytoplasmic antibodies, anti-Saccharomyces cerevisiae antibodies, and specific IgE to food allergens in children with inflammatory bowel diseases
    • Bartunkova J, Kolarova I, Sediva A, Holzelova E: Antineutrophil cytoplasmic antibodies, anti-Saccharomyces cerevisiae antibodies, and specific IgE to food allergens in children with inflammatory bowel diseases. Clin Immunol 2002;102:162-168.
    • (2002) Clin Immunol , vol.102 , pp. 162-168
    • Bartunkova, J.1    Kolarova, I.2    Sediva, A.3    Holzelova, E.4
  • 5
    • 0036242774 scopus 로고    scopus 로고
    • The value of serologic markers in indeterminate colitis: A prospective follow-up study
    • Joossens S, Reinisch W, Vermeire S, Sendid B, Poulain D, Peeters M, et al: The value of serologic markers in indeterminate colitis: A prospective follow-up study. Gastroenterology 2002;122:1242-1247.
    • (2002) Gastroenterology , vol.122 , pp. 1242-1247
    • Joossens, S.1    Reinisch, W.2    Vermeire, S.3    Sendid, B.4    Poulain, D.5    Peeters, M.6
  • 6
    • 0036084752 scopus 로고    scopus 로고
    • Serological markers for prediction of response to anti-tumor necrosis factor treatment in Crohn's disease
    • Esters N, Vermeire S, Joossens S, Noman M, Louis E, Belaiche J, et al: Serological markers for prediction of response to anti-tumor necrosis factor treatment in Crohn's disease. Am J Gastroenterol 2002;97:1458-1462.
    • (2002) Am J Gastroenterol , vol.97 , pp. 1458-1462
    • Esters, N.1    Vermeire, S.2    Joossens, S.3    Noman, M.4    Louis, E.5    Belaiche, J.6
  • 7
    • 0036946773 scopus 로고    scopus 로고
    • Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value
    • Glas J, Torok HP, Vilsmaier F, Herbinger KH, Hoelscher M, Folwaczny C: Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value. Digestion 2002;66:173-177.
    • (2002) Digestion , vol.66 , pp. 173-177
    • Glas, J.1    Torok, H.P.2    Vilsmaier, F.3    Herbinger, K.H.4    Hoelscher, M.5    Folwaczny, C.6
  • 8
    • 0036735003 scopus 로고    scopus 로고
    • Evaluation of serological markers to differentiate between ulcerative colitis and Crohn's disease: pANCA, ASCA and agglutinating antibodies to anaerobic coccoid rods
    • Linskens RK, Mallant-Hent RC, GroothuisMink ZM, Bakker-Jonges LE, van de Merwe JP, Hooijkaas H, et al: Evaluation of serological markers to differentiate between ulcerative colitis and Crohn's disease: pANCA, ASCA and agglutinating antibodies to anaerobic coccoid rods. Eur J Gastroenterol Hepatol 2002;14:1013-1018.
    • (2002) Eur J Gastroenterol Hepatol , vol.14 , pp. 1013-1018
    • Linskens, R.K.1    Mallant-Hent, R.C.2    GroothuisMink, Z.M.3    Bakker-Jonges, L.E.4    Van De Merwe, J.P.5    Hooijkaas, H.6
  • 12
    • 0034746197 scopus 로고    scopus 로고
    • HLA-DRB1*03, DRB1*11 or DRB1*12 and their respective DRB3 specificities in clinical variants of sarcoidosis
    • Bogunia-Kubik K, Tomeczko J, Suchnicki K, Lange A: HLA-DRB1*03, DRB1*11 or DRB1*12 and their respective DRB3 specificities in clinical variants of sarcoidosis. Tissue Antigens 2001;57:87-90.
    • (2001) Tissue Antigens , vol.57 , pp. 87-90
    • Bogunia-Kubik, K.1    Tomeczko, J.2    Suchnicki, K.3    Lange, A.4
  • 13
    • 0036253051 scopus 로고    scopus 로고
    • Clinical, immunological, and immunogenetic aspects of autoantibody production against Ro/SSA, La/SSB and their linear epitopes in primary Sjögren's syndrome (pSS): A European multi-centre study
    • Tzioufas AG, Wassmuth R, Dafni UG, Guialis A, Haga HJ, Isenberg DA, et al: Clinical, immunological, and immunogenetic aspects of autoantibody production against Ro/SSA, La/SSB and their linear epitopes in primary Sjögren's syndrome (pSS): A European multi-centre study. Ann Rheum Dis 2002;61:398-404.
    • (2002) Ann Rheum Dis , vol.61 , pp. 398-404
    • Tzioufas, A.G.1    Wassmuth, R.2    Dafni, U.G.3    Guialis, A.4    Haga, H.J.5    Isenberg, D.A.6
  • 14
    • 0031888241 scopus 로고
    • Identifying Crohn's disease patients with a high risk of relapse
    • Timmer A, Sutherland LR: Identifying Crohn's disease patients with a high risk of relapse. Res Clin Forums 1988;20:77-86.
    • (1988) Res Clin Forums , vol.20 , pp. 77-86
    • Timmer, A.1    Sutherland, L.R.2
  • 15
    • 0036255811 scopus 로고    scopus 로고
    • Opinion: Candidate-gene approaches for studying complex genetic traits: Practical considerations
    • Tabor HK, Risch NJ, Myers RM: Opinion: Candidate-gene approaches for studying complex genetic traits: Practical considerations. Nat Rev Genet 2002;3:391-397.
    • (2002) Nat Rev Genet , vol.3 , pp. 391-397
    • Tabor, H.K.1    Risch, N.J.2    Myers, R.M.3
  • 16
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, et al: Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001;411:599-603.
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1    Chamaillard, M.2    Zouali, H.3    Lesage, S.4    Cezard, J.P.5    Belaiche, J.6
  • 17
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, et al: A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001;411:603-606.
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1    Bonen, D.K.2    Inohara, N.3    Nicolae, D.L.4    Chen, F.F.5    Ramos, R.6
  • 18
    • 0035897904 scopus 로고    scopus 로고
    • Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
    • Hampe J, Cuthbert A, Croucher PJ, Mirza MM, Mascheretti S, Fisher S, et al: Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 2001;357:1925-1928.
    • (2001) Lancet , vol.357 , pp. 1925-1928
    • Hampe, J.1    Cuthbert, A.2    Croucher, P.J.3    Mirza, M.M.4    Mascheretti, S.5    Fisher, S.6
  • 20
    • 0037379915 scopus 로고    scopus 로고
    • TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells
    • Rosenstiel P, Fantini M, Brautigam K, Kuhbacher T, Waetzig GH, Seegert D, et al: TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells. Gastroenterology 2003;124:1001-1009.
    • (2003) Gastroenterology , vol.124 , pp. 1001-1009
    • Rosenstiel, P.1    Fantini, M.2    Brautigam, K.3    Kuhbacher, T.4    Waetzig, G.H.5    Seegert, D.6
  • 22
    • 18244366407 scopus 로고    scopus 로고
    • Simple genotype analysis of the Asp299Gly polymorphism of the Toll-like receptor-4 gene that is associated with lipopolysaccharide hyporesponsiveness
    • Okayama N, Fujimura K, Suehiro Y, Hamanaka Y, Fujiwara M, Matsubara T, et al: Simple genotype analysis of the Asp299Gly polymorphism of the Toll-like receptor-4 gene that is associated with lipopolysaccharide hyporesponsiveness. J Clin Lab Anal 2002;16:56-58.
    • (2002) J Clin Lab Anal , vol.16 , pp. 56-58
    • Okayama, N.1    Fujimura, K.2    Suehiro, Y.3    Hamanaka, Y.4    Fujiwara, M.5    Matsubara, T.6
  • 23
    • 0037373316 scopus 로고    scopus 로고
    • A novel NOD2/CARD15 haplotype conferring risk for Crohn disease in Ashkenazi Jews
    • Sugimura K, Taylor KD, Lin YC, Hang T, Wang D, Tang YM, et al: A novel NOD2/CARD15 haplotype conferring risk for Crohn disease in Ashkenazi Jews. Am J Hum Genet 2003;72:509-518.
    • (2003) Am J Hum Genet , vol.72 , pp. 509-518
    • Sugimura, K.1    Taylor, K.D.2    Lin, Y.C.3    Hang, T.4    Wang, D.5    Tang, Y.M.6
  • 25
    • 0036373539 scopus 로고    scopus 로고
    • Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease
    • Yamazaki K, Takazoe M, Tanaka T, Kazumori T, Nakamura Y: Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease. J Hum Genet 2002;47:469-472.
    • (2002) J Hum Genet , vol.47 , pp. 469-472
    • Yamazaki, K.1    Takazoe, M.2    Tanaka, T.3    Kazumori, T.4    Nakamura, Y.5
  • 26
    • 0037265610 scopus 로고    scopus 로고
    • Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations
    • Croucher PJ, Mascheretti S, Hampe J, Huse K, Frenzel H, Stoll M, et al: Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations. Eur J Hum Genet 2003;11:6-16.
    • (2003) Eur J Hum Genet , vol.11 , pp. 6-16
    • Croucher, P.J.1    Mascheretti, S.2    Hampe, J.3    Huse, K.4    Frenzel, H.5    Stoll, M.6
  • 28
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • Aderem A, Ulevitch RJ: Toll-like receptors in the induction of the innate immune response. Nature 2000;406:782-787.
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.J.2
  • 29
    • 0034445697 scopus 로고    scopus 로고
    • Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
    • Cario E, Podolsky DK: Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun 2000;68:7010-7017.
    • (2000) Infect Immun , vol.68 , pp. 7010-7017
    • Cario, E.1    Podolsky, D.K.2
  • 31
    • 0034906019 scopus 로고    scopus 로고
    • Autoimmunity and apoptosis: The Crohn's connection
    • Beutler B: Autoimmunity and apoptosis: The Crohn's connection. Immunity 2001;15:5-14.
    • (2001) Immunity , vol.15 , pp. 5-14
    • Beutler, B.1
  • 32
    • 0032875134 scopus 로고    scopus 로고
    • Innate mechanisms of epithelial host defense: Spotlight on intestine
    • Hecht G: Innate mechanisms of epithelial host defense: Spotlight on intestine. Am J Physiol 1999;277:C351-358.
    • (1999) Am J Physiol , vol.277
    • Hecht, G.1
  • 33
    • 0034886388 scopus 로고    scopus 로고
    • The Nod2 gene in Crohn's disease: Implications for future research into the genetics and immunology of Crohn's disease
    • Cho JH: The Nod2 gene in Crohn's disease: Implications for future research into the genetics and immunology of Crohn's disease. Inflamm Bowel Dis 2001;7:271-275.
    • (2001) Inflamm Bowel Dis , vol.7 , pp. 271-275
    • Cho, J.H.1
  • 34
    • 0034177513 scopus 로고    scopus 로고
    • Lactobacilli Streptococci activate NF-kappa B. STAT signaling pathways in human macrophages
    • Miettinen M, Lehtonen A, Julkunen I, Matikainen S: Lactobacilli and Streptococci activate NF-kappa B and STAT signaling pathways in human macrophages. J Immunol 2000;164:3733-3740.
    • (2000) J Immunol , vol.164 , pp. 3733-3740
    • Miettinen, M.1    Lehtonen, A.2    Julkunen, I.3    Matikainen, S.4
  • 35
    • 0034850005 scopus 로고    scopus 로고
    • Induction of nitric oxide synthesis by probiotic Lactobacillus rhamnosus GG in J774 macrophages and human T84 intestinal epithelial cells
    • Korhonen R, Korpela R, Saxelin M, Maki M, Kankaanranta H, Moilanen E: Induction of nitric oxide synthesis by probiotic Lactobacillus rhamnosus GG in J774 macrophages and human T84 intestinal epithelial cells. Inflammation 2001;25:223-232.
    • (2001) Inflammation , vol.25 , pp. 223-232
    • Korhonen, R.1    Korpela, R.2    Saxelin, M.3    Maki, M.4    Kankaanranta, H.5    Moilanen, E.6
  • 36
    • 0038587747 scopus 로고    scopus 로고
    • The two faces of IKK and NF-kappaB inhibition: Prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion
    • Chen LW, Egan L, Li ZW, Greten FR, Kagnoff MF, Karin M: The two faces of IKK and NF-kappaB inhibition: Prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat Med 2003;9:575-581.
    • (2003) Nat Med , vol.9 , pp. 575-581
    • Chen, L.W.1    Egan, L.2    Li, Z.W.3    Greten, F.R.4    Kagnoff, M.F.5    Karin, M.6
  • 37
    • 0033591330 scopus 로고    scopus 로고
    • Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappa B
    • Inohara N, Koseki T, del Peso L, Hu Y, Yee C, Chen S, et al: Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappa B. J Biol Chem 1999;274:14560-14567.
    • (1999) J Biol Chem , vol.274 , pp. 14560-14567
    • Inohara, N.1    Koseki, T.2    Del Peso, L.3    Hu, Y.4    Yee, C.5    Chen, S.6
  • 38
    • 0035474227 scopus 로고    scopus 로고
    • The NOD: A signaling module that regulates apoptosis and host defense against pathogens
    • Inohara N, Nunez G: The NOD: A signaling module that regulates apoptosis and host defense against pathogens. Oncogene 2001;20:6473-6481.
    • (2001) Oncogene , vol.20 , pp. 6473-6481
    • Inohara, N.1    Nunez, G.2
  • 39
    • 18044399494 scopus 로고    scopus 로고
    • Three views of genetics: The enthusiast, the visionary, and the sceptic. Interview by Tessa Richards
    • Burn J, Duff G, Holtzman N: Three views of genetics: the enthusiast, the visionary, and the sceptic. Interview by Tessa Richards. BMJ 2001;322:1016.
    • (2001) BMJ , vol.322 , pp. 1016
    • Burn, J.1    Duff, G.2    Holtzman, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.