The cytoprotective aminothiol WR1065 activates p21(waf-1) and down regulates cell cycle progression through a p53-dependent pathway

Oncogene

Volumn 19, Issue 9, 2000, Pages 1206-1214

  North, S ^a   El Ghissassi, F ^a,b   Pluquet, O ^a   Verhaegh, G ^a,c   Hainaut, P ^a  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b CENTRE LÉON BÉRARD   (France)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cell cycle; p53; Radioprotection; Redox control; WR1065

Indexed keywords

2 (3 AMINOPROPYLAMINO)ETHANETHIOL; AMIFOSTINE; AMINOGUANIDINE; ANTIOXIDANT; CYCLIN DEPENDENT KINASE INHIBITOR; HYDROGEN PEROXIDE; PROTEIN P21; PROTEIN P53; RADIOPROTECTIVE AGENT; SPERMIDINE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BREAST CANCER; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROTECTION; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG EFFECT; ENZYME INDUCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; RADIATION PROTECTION; TUMOR SUPPRESSOR GENE;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS;

EID: 0034708220     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203413     Document Type: Article

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