Preferential Metabolic Activation of N-Nitrosopiperidine as Compared to Its Structural Homologue N-Nitrosopyrrolidine by Rat Nasal Mucosal Microsomes

Chemical Research in Toxicology

Volumn 16, Issue 10, 2003, Pages 1298-1305

  Wong, Hansen L ^a   Murphy, Sharon E ^a   Hecht, Stephen S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 NITROSOPIPERIDINE; 2 HYDROXY 5 METHYLTETRAHYDROFURAN; 2 HYDROXYTETRAHYDRO 2H PYRAN; 2 HYDROXYTETRAHYDROFURAN; ANTIBODY; COUMARIN; CYTOCHROME P450; CYTOCHROME P450 2A6; N NITROSOPYRROLIDINE; NITROSAMINE; TETRAHYDROFURAN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CATALYSIS; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; MALE; METABOLIC ACTIVATION; MICROSOME; NONHUMAN; NOSE CAVITY; NOSE MUCOSA; OLFACTORY SYSTEM; RAT; RESPIRATORY EPITHELIUM; TISSUE SPECIFICITY; TITRIMETRY; TOXICOKINETICS; ULTRAVIOLET RADIATION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; HUMANS; HYDROXYLATION; IMMUNOGLOBULIN G; KINETICS; MALE; MICROSOMES; MIXED FUNCTION OXYGENASES; MOLECULAR STRUCTURE; N-NITROSOPYRROLIDINE; NASAL MUCOSA; NITROSAMINES; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0142169952     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0340495     Document Type: Article

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