Evidence for metabolic activation of N'-nitrosonomicotine and N- nitrosobenzylmethylamine by a rat nasal coumarin hydroxylase

Drug Metabolism and Disposition

Volumn 26, Issue 2, 1998, Pages 177-180

  Murphy, Sharon E ^a   Patten, Christopher J ^b   Peterson, Lisa A ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BENZALDEHYDE; COUMARIN; ETHOXYCOUMARIN; N BENZYL N METHYLNITROSAMINE; NITROSONORNICOTINE; OXYGENASE;

ANIMAL EXPERIMENT; ARTICLE; CARCINOGENICITY; CATALYSIS; DNA ADDUCT; DRUG METABOLISM; ENZYME ACTIVATION; HYDROXYLATION; MICROSOME; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL; RAT;

7-ALKOXYCOUMARIN O-DEALKYLASE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CARCINOGENS; COUMARINS; CYTOCHROME P-450 ENZYME SYSTEM; DIMETHYLNITROSAMINE; ENZYME INHIBITORS; HYDROXYLATION; KINETICS; MALE; METHOXSALEN; MICROSOMES; MIXED FUNCTION OXYGENASES; NASAL MUCOSA; NITROSAMINES; NITROSO COMPOUNDS; PLANTS, TOXIC; RATS; RATS, INBRED F344; TOBACCO;

ANIMALIA; NICOTIANA TABACUM;

EID: 0344765490     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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