Lactols in hydrolysates of DNA treated with α-acetoxy-n- nitrosopyrrolidine or crotonaldehyde

Chemical Research in Toxicology

Volumn 11, Issue 12, 1998, Pages 1567-1573

  Wang, Mingyao ^a   Upadhyaya, Pramod ^a   Dinh, Trieu T ^a   Bonilla, Leo E ^a   Hecht, Stephen S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 ACETOXY 1 NITROSOPYRROLIDINE; CROTONALDEHYDE; LACTIC ACID 2 NAPHTHYL ESTER; LACTONE DERIVATIVE; NITROSO DERIVATIVE; PROTEIN HYDROLYSATE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENICITY; DIET; DNA ADDUCT; DNA MODIFICATION; LIVER CARCINOMA; MUTAGENICITY; SMOKING; SPECTROPHOTOMETER;

ALDEHYDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; HYDROLYSIS; LACTATES; MASS SPECTROMETRY; MUTAGENS; N-NITROSOPYRROLIDINE; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0032437976     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx980165+     Document Type: Article

References (4)

1. Baldwin, J. E., and Branz, S. E. (1976) Chemical activation of nitrosamines into mutagenic agents. Tetrahedron Lett., 333-336.
2. Hecht, S. S., Chen, C. B., and Hoffmann, D. (1978) Evidence for metabolic α-hydroxylation of N-nitrosopyrrolidine. Cancer Res. 38, 215-218.
3. Preussmann, R., and Stewart, B. W. (1984) N-Nitroso carcinogens. In Chemical Carcinogenesis (Searle, C. E., Ed.) pp 643-828, American Chemical Society, Washington, DC.
4. Tricker, A. R., Pfundstein, B., Theobald, E., Preussmann, R., and Spiegelhalder, B. (1991) Mean daily intake of volatile N-nitrosamines from foods and beverages in West Germany in 1989-1990. Food Chem. Toxicol. 29, 729-732.