pH-Triggered Release of Macromolecules from Spray-Dried Polymethacrylate Microparticles

Pharmaceutical Research

Volumn 20, Issue 10, 2003, Pages 1533-1538

  Kohane, Daniel S ^a,b   Andersen, Daniel G ^b   Yu, Christine ^c   Langer, Robert ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Biocompatibility; Controlled release; Drug delivery; Intracellular

Indexed keywords

E 100; EUDRAGIT; LIPID; POLYMETHACRYLIC ACID; PROTEIN;

ACIDITY; ANIMAL EXPERIMENT; ARTICLE; BIOCOMPATIBILITY; BRAIN; CONNECTIVE TISSUE; CONTROLLED STUDY; DENSITY; DRUG EFFICACY; DRUG RELEASE; DRUG SAFETY; EDEMA; ELECTRON MICROSCOPY; FLUORESCENCE; INFLAMMATION; KINETICS; MEASUREMENT; MOLECULE; MOUSE; MUSCLE TISSUE; NERVE; NERVOUS TISSUE; NONHUMAN; PARTICLE SIZE; PH MEASUREMENT; PRIORITY JOURNAL; SPRAY DRYING;

ACRYLATES; ALBUMINS; ANIMALS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; EXCIPIENTS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; INFLAMMATION; INJECTIONS, INTRAMUSCULAR; LACTALBUMIN; MALE; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; POLYMERS; POLYMETHACRYLIC ACIDS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 0142105948     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026162628965     Document Type: Article

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