Biocompatibility of lipid-protein-sugar particles containing bupivacaine in the epineurium

Journal of Biomedical Materials Research

Volumn 59, Issue 3, 2002, Pages 450-459

  Kohane, Daniel S ^a   Langer, Robert ^b   Kinney, Ramsey C ^b   Lipp, Michael ^b   Lotan, Noah ^d   Louis, David N ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Biocompatibility; Bupivacaine; Controlled release; Inflammation; Prolonged duration local anesthesia; Sciatic nerve

Indexed keywords

FOREIGN-BODY GIANT CELLS;

BIOCOMPATIBILITY; HISTOLOGY; LIPIDS; PROTEINS; SUGARS; TISSUE;

BIOMATERIALS;

ALBUMIN; BUPIVACAINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; LACTOSE; LIPID; MICROSPHERE; PROTEIN; SUGAR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CONTROLLED STUDY; GIANT CELL; HISTIOCYTOSIS; HISTOLOGY; INFLAMMATION; LOCAL ANESTHESIA; MALE; NERVE BLOCK; NONHUMAN; PARTICLE SIZE; RAT; SCIATIC NERVE; SUSTAINED RELEASE PREPARATION;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; ANESTHETICS, LOCAL; ANIMALS; BIOCOMPATIBLE MATERIALS; BUPIVACAINE; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; INFLAMMATION; LACTIC ACID; LACTOSE; MALE; MICROSPHERES; NERVE BLOCK; PERIPHERAL NERVES; POLYGLYCOLIC ACID; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SERUM ALBUMIN; TIME FACTORS;

EID: 0037022703     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.1261     Document Type: Article

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