Characterization of human nasal primary culture systems to investigate peptide metabolism

International Journal of Pharmaceutics

Volumn 238, Issue 1-2, 2002, Pages 247-256

  Hoang, Vu Dang ^a   Uchenna, Agu Remigius ^a   Mark, Jorissen ^a   Renaat, Kinget ^a   Norbert, Verbeke ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Leucine enkephalin; Metabolism; Nasal cell culture; Peptides; Protease inhibitors

Indexed keywords

BESTATIN; COLLAGEN; DRUG METABOLITE; GLYCYLPHENYLALANYLLEUCINE; LEUCINE ENKEPHALIN; PEPTIDE; PHENYLALANYLLEUCINE; PROTEINASE; PUROMYCIN; TYROSYLGLYCINE; TYROSYLGLYCYLGLYCINE; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG DETERMINATION; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG STABILITY; EPITHELIUM CELL; FIRST PASS EFFECT; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMERSION; MODEL; MONOLAYER CULTURE; NOSE MUCOSA; PRIORITY JOURNAL; PROTEIN METABOLISM;

CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLLAGEN; CULTURE MEDIA; CYTOLOGICAL TECHNIQUES; ENKEPHALIN, LEUCINE; EPITHELIAL CELLS; HUMANS; KINETICS; NASAL MUCOSA; PEPTIDES; PHARMACEUTICAL PREPARATIONS; PROTEASE INHIBITORS; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0037093741     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(02)00077-7     Document Type: Article

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