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Volumn 23, Issue 3, 2003, Pages 179-186

Retinoic acid modulates the cell-cycle in fetal rat hepatocytes and HepG2 cells by regulating cyclin-cdk activities

Author keywords

Cell cycle inhibitors; Cyclin A E cdk2; Cyclin D1 cdk4; Hepatocytes; Retinoic acid

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; MYC PROTEIN; PROTEIN BCL 2; PROTEIN INHIBITOR; PROTEIN P16; PROTEIN P21; PROTEIN P27; RETINOIC ACID;

EID: 0142061469     PISSN: 14783223     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0676.2003.00829.x     Document Type: Article
Times cited : (41)

References (38)
  • 1
    • 0028171292 scopus 로고
    • G1 phase progression: Cycling on cue
    • Sherr C J. G1 phase progression: cycling on cue. Cell 1994; 79: 551-6.
    • (1994) Cell , vol.79 , pp. 551-556
    • Sherr, C.J.1
  • 2
    • 0031466305 scopus 로고    scopus 로고
    • Cyclin-dependent kinases: Engines, clocks, microprocessors
    • Morgan D O. Cyclin-dependent kinases: engines, clocks, microprocessors. Annu Rev Cell Dev Biol 1997; 13: 261-91.
    • (1997) Annu. Rev. Cell Dev. Biol. , vol.13 , pp. 261-291
    • Morgan, D.O.1
  • 3
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr C J, Roberts J M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999; 13: 1501-12.
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 4
    • 0033135878 scopus 로고    scopus 로고
    • Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation
    • Montagnoli A, Fiore F, Eytan E, et al. Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation. Genes Dev 1999; 13: 1181-9.
    • (1999) Genes Dev. , vol.13 , pp. 1181-1189
    • Montagnoli, A.1    Fiore, F.2    Eytan, E.3
  • 5
    • 0035123105 scopus 로고    scopus 로고
    • Ubiquitin-mediated proteolysis of vertebrate G1-and S-phase regulators
    • Yew P R. Ubiquitin-mediated proteolysis of vertebrate G1-and S-phase regulators. J Cell Physiol 2001; 187: 1-10.
    • (2001) J. Cell Physiol. , vol.187 , pp. 1-10
    • Yew, P.R.1
  • 6
    • 0035895604 scopus 로고    scopus 로고
    • Regulation of G1 to S transition by the ubiquitin pathway
    • Desalle L M, Pagano M. Regulation of G1 to S transition by the ubiquitin pathway. FEBS Lett 2001; 490: 179-89.
    • (2001) FEBS Lett. , vol.490 , pp. 179-189
    • Desalle, L.M.1    Pagano, M.2
  • 7
    • 0033304945 scopus 로고    scopus 로고
    • The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation
    • Pestell R G, Albanese C, Reutens A T, et al. The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation. Endocrine Rev 2000; 20: 501-34.
    • (2000) Endocrine Rev. , vol.20 , pp. 501-534
    • Pestell, R.G.1    Albanese, C.2    Reutens, A.T.3
  • 8
    • 0033735581 scopus 로고    scopus 로고
    • Cell cycle checkpoints and their inactivation in human cancer
    • Molinari M. Cell cycle checkpoints and their inactivation in human cancer. Cell Prolif 2000; 33: 261-74.
    • (2000) Cell Prolif. , vol.33 , pp. 261-274
    • Molinari, M.1
  • 10
    • 0029796637 scopus 로고    scopus 로고
    • Retinoids in cancer chemioprevention
    • Lotan R. Retinoids in cancer chemioprevention. FASEB J 1996; 10: 1031-9.
    • (1996) FASEB J. , vol.10 , pp. 1031-1039
    • Lotan, R.1
  • 11
    • 0025176042 scopus 로고
    • Ligand-activated thyroid hormone and retinoic acid receptors inhibit growth factor receptor promoter expression
    • Hudson L G, Santon J B, Glass C K, et al. Ligand-activated thyroid hormone and retinoic acid receptors inhibit growth factor receptor promoter expression. Cell 1990; 62: 1165-75.
    • (1990) Cell , vol.62 , pp. 1165-1175
    • Hudson, L.G.1    Santon, J.B.2    Glass, C.K.3
  • 12
    • 0029955958 scopus 로고    scopus 로고
    • Transcriptional activation of the human p21 (WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation
    • Liu M, Iavarone A, Freedman L P. Transcriptional activation of the human p21 (WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation. J Biol Chem 1996; 271: 31723-8.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31723-31728
    • Liu, M.1    Iavarone, A.2    Freedman, L.P.3
  • 13
    • 0028588121 scopus 로고
    • All-trans retinoic acid for treatment of AIDS-related Kaposi's sarcoma: Results of a pilot phase II study
    • Gill P S, Espina B M, Moudgil T, et al. All-trans retinoic acid for treatment of AIDS-related Kaposi's sarcoma: results of a pilot phase II study. Leukemia 1994; 8: S26-32.
    • (1994) Leukemia , vol.8
    • Gill, P.S.1    Espina, B.M.2    Moudgil, T.3
  • 14
    • 0031417682 scopus 로고    scopus 로고
    • Retinoids in neuroblastoma theraphy: Distinct biological properties of 9-cis and all-trans-retinoic acid
    • Lovat P E, Irving H, Annichiarico-Petruzzelli M, et al. Retinoids in neuroblastoma theraphy: distinct biological properties of 9-cis and all-trans-retinoic acid. Eur J Cancer 1997; 33: 2075-80.
    • (1997) Eur. J. Cancer , vol.33 , pp. 2075-2080
    • Lovat, P.E.1    Irving, H.2    Annichiarico-Petruzzelli, M.3
  • 15
    • 0033780902 scopus 로고    scopus 로고
    • Retinoids in breast cancer prevention and treatment. A review of the literature
    • Baj G, Arnulfo A, Deaglio S, et al. Retinoids in breast cancer prevention and treatment. A review of the literature. Eur J Gynaecol Oncol 2000; 4: 411-5.
    • (2000) Eur. J. Gynaecol. Oncol. , vol.4 , pp. 411-415
    • Baj, G.1    Arnulfo, A.2    Deaglio, S.3
  • 16
    • 0031461602 scopus 로고    scopus 로고
    • CDK2 is a target for retinoic acid-mediated growth inhibition in MCF-7 human breast cancer cells
    • Texeira C, Pratt M A. CDK2 is a target for retinoic acid-mediated growth inhibition in MCF-7 human breast cancer cells. Mol Endocrinol 1997; 11: 1191-202.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 1191-1202
    • Texeira, C.1    Pratt, M.A.2
  • 17
    • 0032528172 scopus 로고    scopus 로고
    • Retinoic acid-induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) activation is needed to elicit HL-60 cell differentiation and growth arrest
    • Yen A, Roberson M S, Varvayanis S, et al. Retinoic acid-induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) activation is needed to elicit HL-60 cell differentiation and growth arrest. Cancer Res 1998; 58: 3163-71.
    • (1998) Cancer Res. , vol.58 , pp. 3163-3171
    • Yen, A.1    Roberson, M.S.2    Varvayanis, S.3
  • 18
    • 0032565767 scopus 로고    scopus 로고
    • P27 kip1: A key mediator of retinoic acid induced growth arrest in the SMS-KCNR human neuroblastoma cell line
    • Matsuo T, Thiele C J. P27 kip1: a key mediator of retinoic acid induced growth arrest in the SMS-KCNR human neuroblastoma cell line. Oncogene 1998; 16: 3337-43.
    • (1998) Oncogene , vol.16 , pp. 3337-3343
    • Matsuo, T.1    Thiele, C.J.2
  • 19
    • 0030691026 scopus 로고    scopus 로고
    • Posttraslational regulation of cyclin D1 by retinoic acid: A chemoprevention mechanism
    • Langefeld J, Kiyokawa H, Sekula D, et al. Posttraslational regulation of cyclin D1 by retinoic acid: a chemoprevention mechanism. Proc Natl Acad Sci USA 1997; 94: 12070-4.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12070-12074
    • Langefeld, J.1    Kiyokawa, H.2    Sekula, D.3
  • 20
    • 0033764652 scopus 로고    scopus 로고
    • Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27
    • Baldassarre G, Boccia A, Bruni P, et al. Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27. Cell Growth Diff 2000; 11: 517-23.
    • (2000) Cell Growth Diff. , vol.11 , pp. 517-523
    • Baldassarre, G.1    Boccia, A.2    Bruni, P.3
  • 21
    • 0031874769 scopus 로고    scopus 로고
    • The effect of retinoic acid on the reestablishment of differentiated hepatocyte phenotype in primary culture
    • Falasca L, Favale A, Serafino A, et al. The effect of retinoic acid on the reestablishment of differentiated hepatocyte phenotype in primary culture. Cell Tissue Res 1998; 293: 337-47.
    • (1998) Cell Tissue Res. , vol.293 , pp. 337-347
    • Falasca, L.1    Favale, A.2    Serafino, A.3
  • 22
    • 0031720914 scopus 로고    scopus 로고
    • Retinoic acid treatment induces apoptosis or expression of a more differentiated phenotype in different fractions of cultured fetal rat hepatocytes
    • Falasca L, Favale A, Gualandi G, et al. Retinoic acid treatment induces apoptosis or expression of a more differentiated phenotype in different fractions of cultured fetal rat hepatocytes. Hepatology 1998; 28: 727-37.
    • (1998) Hepatology , vol.28 , pp. 727-737
    • Falasca, L.1    Favale, A.2    Gualandi, G.3
  • 23
    • 0033452562 scopus 로고    scopus 로고
    • Growth inhibition and induction of specific hepatic phenotype expression by retinoic acid in HepG2 cells
    • Falasca L, Marcellini P, Ara C, et al. Growth inhibition and induction of specific hepatic phenotype expression by retinoic acid in HepG2 cells. Anticancer Res 1999; 19: 3283-92.
    • (1999) Anticancer Res. , vol.19 , pp. 3283-3292
    • Falasca, L.1    Marcellini, P.2    Ara, C.3
  • 24
    • 0019719798 scopus 로고
    • An improved non-perfusion method for the isolation and purification of rat fetal and neonatal hepatocytes
    • Conti Devirgiliis L, Dini L, Di Pierro A, et al. An improved non-perfusion method for the isolation and purification of rat fetal and neonatal hepatocytes. Cell Mol Biol 1981; 27: 687-94.
    • (1981) Cell Mol. Biol. , vol.27 , pp. 687-694
    • Conti Devirgiliis, L.1    Dini, L.2    Di Pierro, A.3
  • 25
    • 71849104860 scopus 로고
    • Protein measurement with the folin phenol reagent
    • Lowry O H, Rosebrough N T, Farr A L, et al. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265-75.
    • (1951) J. Biol. Chem. , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.T.2    Farr, A.L.3
  • 26
    • 0034638628 scopus 로고    scopus 로고
    • Accelerated growth of hepatocytes in association with up-regulation of cyclin E in transgenic mice expressing the dominant negative form of retinoic acid receptor
    • Tsutumi A, Shiota G, Yamazaki H, et al. Accelerated growth of hepatocytes in association with up-regulation of cyclin E in transgenic mice expressing the dominant negative form of retinoic acid receptor. Biochem Biophys Res Commun 2000; 278: 229-35.
    • (2000) Biochem. Biophys. Res. Commun. , vol.278 , pp. 229-235
    • Tsutumi, A.1    Shiota, G.2    Yamazaki, H.3
  • 27
    • 0033566642 scopus 로고    scopus 로고
    • Retinoic acid prevents phosphorylation of pRb in normal human lymphocytes: Regulation of cyclin E, cyclin A, and p21
    • Naderi B S, Blomhoff H K. Retinoic acid prevents phosphorylation of pRb in normal human lymphocytes: regulation of cyclin E, cyclin A, and p21. Blood 1999; 94: 1348-58.
    • (1999) Blood , vol.94 , pp. 1348-1358
    • Naderi, B.S.1    Blomhoff, H.K.2
  • 28
    • 0033618250 scopus 로고    scopus 로고
    • Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation
    • Spinella M J, Sarah J F, Sekula D, et al. Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation. J Biol Chem 1999; 274: 22013-8.
    • (1999) J. Biol. Chem. , vol.274 , pp. 22013-22018
    • Spinella, M.J.1    Sarah, J.F.2    Sekula, D.3
  • 29
    • 0033541438 scopus 로고    scopus 로고
    • Induction of p21 (Cip/Waf1) and activation of p34 (cdc2) involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells
    • Hsu S L, Chen M C, Chou Y H, et al. Induction of p21 (Cip/Waf1) and activation of p34 (cdc2) involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells. Exp Cells Res 1999; 248: 87-96.
    • (1999) Exp. Cells Res. , vol.248 , pp. 87-96
    • Hsu, S.L.1    Chen, M.C.2    Chou, Y.H.3
  • 30
    • 0025612655 scopus 로고
    • Retinoid-sensitive cells and cell lines
    • Amos B, Lotan R. Retinoid-sensitive cells and cell lines. Meth Enzymol 1990; 190: 217-25.
    • (1990) Meth. Enzymol. , vol.190 , pp. 217-225
    • Amos, B.1    Lotan, R.2
  • 31
    • 0027992556 scopus 로고
    • Apoptosis during retinoic induced differentiation of F9 embryonal carcinoma cells
    • Atencia R, Garcia-Sanz M, Unda F, et al. Apoptosis during retinoic induced differentiation of F9 embryonal carcinoma cells. Exp Cell Res 1994; 214: 663-7.
    • (1994) Exp. Cell Res. , vol.214 , pp. 663-667
    • Atencia, R.1    Garcia-Sanz, M.2    Unda, F.3
  • 32
    • 0036125801 scopus 로고    scopus 로고
    • Formation of 8-hydroxydeoxyguanosine and cell-cycle arrest in the rat liver via generation of oxidative stress by phenobarbital: Association with expression profiles of p21 (WAF1/Cip1), cyclin D1 and Ogg1
    • Kinoshita A, Wanibuchi H, Imaoka S, et al. Formation of 8-hydroxydeoxyguanosine and cell-cycle arrest in the rat liver via generation of oxidative stress by phenobarbital: association with expression profiles of p21 (WAF1/Cip1), cyclin D1 and Ogg1. Carcinogenesis 2002; 23: 341-9.
    • (2002) Carcinogenesis , vol.23 , pp. 341-349
    • Kinoshita, A.1    Wanibuchi, H.2    Imaoka, S.3
  • 33
    • 0035859008 scopus 로고    scopus 로고
    • Ectopic expression of cyclin D1 amplifies a retinoic acid-induced mitochondrial death pathways in breast cancer cells
    • Niu M Y, Menard M, Reed J C, et al. Ectopic expression of cyclin D1 amplifies a retinoic acid-induced mitochondrial death pathways in breast cancer cells. Oncogene 2001; 20: 3506-18.
    • (2001) Oncogene , vol.20 , pp. 3506-3518
    • Niu, M.Y.1    Menard, M.2    Reed, J.C.3
  • 34
    • 0033230887 scopus 로고    scopus 로고
    • Up-regulation of cyclin D1 occurs in apoptosis of immature but not mature cerebellar granule neurons in culture
    • Sakai K, Suzuki K, Tanaka S, et al. Up-regulation of cyclin D1 occurs in apoptosis of immature but not mature cerebellar granule neurons in culture. J Neurosci Res 1999; 58: 396-406.
    • (1999) J. Neurosci. Res. , vol.58 , pp. 396-406
    • Sakai, K.1    Suzuki, K.2    Tanaka, S.3
  • 35
    • 0032921489 scopus 로고    scopus 로고
    • Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: A modulator of in vivo programmed cell death?
    • Timsit S, Rivera S, Ouaghi P, et al. Increased cyclin D1 in vulnerable neurons in the hippocampus after ischaemia and epilepsy: a modulator of in vivo programmed cell death? Eur J Neurosci 1999; 11: 263-78.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 263-278
    • Timsit, S.1    Rivera, S.2    Ouaghi, P.3
  • 36
    • 0031585170 scopus 로고    scopus 로고
    • Differential expression of proteins regulating cell cycle progression in growth vs. differentiation
    • 1356
    • Li Z, Hromchak R, Bloch A. Differential expression of proteins regulating cell cycle progression in growth vs. differentiation. Biochim Biophys Acta 1997; 1356: 149-59.
    • (1997) Biochim. Biophys. Acta , pp. 149-159
    • Li, Z.1    Hromchak, R.2    Bloch, A.3
  • 37
    • 0345062128 scopus 로고    scopus 로고
    • Involvement of cyclin D1-cdk5 overexpression and MCM3 cleavage in bax-associated spontaneous apoptosis and differentiation in an A253 human head and neck carcinoma xenograft model
    • Yin M B, Toth K, Cao S, et al. Involvement of cyclin D1-cdk5 overexpression and MCM3 cleavage in bax-associated spontaneous apoptosis and differentiation in an A253 human head and neck carcinoma xenograft model. Int J Cancer 1999; 83: 341-8.
    • (1999) Int. J. Cancer , vol.83 , pp. 341-348
    • Yin, M.B.1    Toth, K.2    Cao, S.3
  • 38
    • 0029744422 scopus 로고    scopus 로고
    • Anti-IgM mediated regulation of c-myc and its possible relationship to apoptosis
    • Kaptein J S, Lin C K E, Wang C L, et al. Anti-IgM mediated regulation of c-myc and its possible relationship to apoptosis. J Biol Chem 1996; 271: 18875-84.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18875-18884
    • Kaptein, J.S.1    Lin, C.K.E.2    Wang, C.L.3


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