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Volumn 11, Issue 9, 1997, Pages 1191-1202

CDK2 is a target for retinoic acid-mediated growth inhibition in MCF-7 human breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE; MESSENGER RNA; PROTEIN P21; PROTEIN P27; REGULATOR PROTEIN; RETINOBLASTOMA PROTEIN; RETINOIC ACID;

EID: 0031461602     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.9.9977     Document Type: Article
Times cited : (93)

References (69)
  • 1
    • 0028283503 scopus 로고
    • Molecular mechanisms of action of steroid/thyroid receptor superfamily members
    • Tsai MJ, O'Malley BW 1994 Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 63:451-486
    • (1994) Annu Rev Biochem , vol.63 , pp. 451-486
    • Tsai, M.J.1    O'Malley, B.W.2
  • 3
    • 0029584593 scopus 로고
    • Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life?
    • Kastner P, Mark M, Chambon P 1995 Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life? Cell 83:859-869
    • (1995) Cell , vol.83 , pp. 859-869
    • Kastner, P.1    Mark, M.2    Chambon, P.3
  • 4
    • 0026927623 scopus 로고
    • Retinoids, retinoid-responsive genes, cell differentiation and cancer
    • Gudas LJ 1992 Retinoids, retinoid-responsive genes, cell differentiation and cancer. Cell Growth Differ 3:655-662
    • (1992) Cell Growth Differ , vol.3 , pp. 655-662
    • Gudas, L.J.1
  • 5
    • 0026762673 scopus 로고
    • Expression and regulation of retinoic acid receptors in human breast cancer cells
    • Roman SD, Clarke CL, Hall RE, Alexander IE, Sutherland RL 1992 Expression and regulation of retinoic acid receptors in human breast cancer cells. Cancer Res 52:2236-2242
    • (1992) Cancer Res , vol.52 , pp. 2236-2242
    • Roman, S.D.1    Clarke, C.L.2    Hall, R.E.3    Alexander, I.E.4    Sutherland, R.L.5
  • 7
    • 0344349549 scopus 로고    scopus 로고
    • The AF-2 region of the RARα mediates retinoic acid inhibition of estrogen receptor function in human breast cancer cells
    • Pratt MAC, Deonarine D, Teixeira C, Novosad D, Tate B, Grippo J 1996 The AF-2 region of the RARα mediates retinoic acid inhibition of estrogen receptor function in human breast cancer cells. J Biol Chem 271: 20346-20353
    • (1996) J Biol Chem , vol.271 , pp. 20346-20353
    • Pratt, M.A.C.1    Deonarine, D.2    Teixeira, C.3    Novosad, D.4    Tate, B.5    Grippo, J.6
  • 8
    • 0028296170 scopus 로고
    • Antiestrogenic effects of all-trans retinoic acid and 1,25-dihydroxyvitamin D3 in breast cancer cells occur at the estrogen response element level but through different molecular mechanisms
    • Demirpence E, Balaguer P, Trousse F, Nicolas J-C, Pons M, Gagne D 1994 Antiestrogenic effects of all-trans retinoic acid and 1,25-dihydroxyvitamin D3 in breast cancer cells occur at the estrogen response element level but through different molecular mechanisms. Cancer Res 54:1458-1464
    • (1994) Cancer Res , vol.54 , pp. 1458-1464
    • Demirpence, E.1    Balaguer, P.2    Trousse, F.3    Nicolas, J.-C.4    Pons, M.5    Gagne, D.6
  • 10
    • 0030066105 scopus 로고    scopus 로고
    • Retinoic acid receptor β mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells
    • Liu Y, Lee MO, Wang H-G, Li Y, Hashimoto Y, Klaus M, Reed JC, Zhang X-K 1996 Retinoic acid receptor β mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells. Mol Cell Biol 16:1138-1149
    • (1996) Mol Cell Biol , vol.16 , pp. 1138-1149
    • Liu, Y.1    Lee, M.O.2    Wang, H.-G.3    Li, Y.4    Hashimoto, Y.5    Klaus, M.6    Reed, J.C.7    Zhang, X.-K.8
  • 11
    • 0028022017 scopus 로고
    • Retinoid-resistant estrogen-receptor-negative human breast carcinoma cells transfected with retinoic acid receptor-α acquire sensitivity to growth inhibition by retinoids
    • Sheikh MS, Shao Z-M, Li X-S, Dawson M, Jetten AM, Wu S, Conley BA, Garcia M, Rochefort H, Fontana JA 1994 Retinoid-resistant estrogen-receptor-negative human breast carcinoma cells transfected with retinoic acid receptor-α acquire sensitivity to growth inhibition by retinoids. J Biol Chem 269:21440-21447
    • (1994) J Biol Chem , vol.269 , pp. 21440-21447
    • Sheikh, M.S.1    Shao, Z.-M.2    Li, X.-S.3    Dawson, M.4    Jetten, A.M.5    Wu, S.6    Conley, B.A.7    Garcia, M.8    Rochefort, H.9    Fontana, J.A.10
  • 12
    • 0022345650 scopus 로고
    • Effects of 4-hydroxy-phenylretinamide and retinoic acid on proliferation and cell cycle of cultured human breast cancer cells
    • Marth C, Bock G, Daxenbichler G 1985 Effects of 4-hydroxy-phenylretinamide and retinoic acid on proliferation and cell cycle of cultured human breast cancer cells. J Natl Cancer Inst 75:871-875
    • (1985) J Natl Cancer Inst , vol.75 , pp. 871-875
    • Marth, C.1    Bock, G.2    Daxenbichler, G.3
  • 13
    • 0028931265 scopus 로고
    • Priniciples of cdk regulation
    • Morgan DO 1995 Priniciples of cdk regulation. Nature 374:131-134
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 14
    • 0026693966 scopus 로고
    • Animal cell cycles and their control
    • Norbury C, Nurse P 1992 Animal cell cycles and their control. Annu Rev Biochem 61:441-470
    • (1992) Annu Rev Biochem , vol.61 , pp. 441-470
    • Norbury, C.1    Nurse, P.2
  • 15
    • 0026031941 scopus 로고
    • G1-specific cyclins: In search of an S phase promoting factor
    • Reed SI 1991 G1-specific cyclins: in search of an S phase promoting factor. Trends Genet 7:95-99
    • (1991) Trends Genet , vol.7 , pp. 95-99
    • Reed, S.I.1
  • 16
    • 0027336491 scopus 로고
    • Mammalian G1 cyclins: Review
    • Sherr CJ 1993 Mammalian G1 cyclins: review. Cell 73:1059-1065
    • (1993) Cell , vol.73 , pp. 1059-1065
    • Sherr, C.J.1
  • 17
    • 0026713875 scopus 로고
    • Cell cycle regulation of cdk2 activity by phosphorylation of Thr 160 and Tyr 15
    • Gu Y, Rosenblatt J, Morgan DO 1992 Cell cycle regulation of cdk2 activity by phosphorylation of Thr 160 and Tyr 15. EMBO J 11:3995-4005
    • (1992) EMBO J , vol.11 , pp. 3995-4005
    • Gu, Y.1    Rosenblatt, J.2    Morgan, D.O.3
  • 18
    • 0027943714 scopus 로고
    • Activation of cyclin dependent kinase 4 (cdk4) by mouse MO15-associated kinase
    • Matsuoka M, Kato J, Fisher R, Morgan DO, Sherr CJ 1994 Activation of cyclin dependent kinase 4 (cdk4) by mouse MO15-associated kinase. Mol Cell Biol 14:7265-7275
    • (1994) Mol Cell Biol , vol.14 , pp. 7265-7275
    • Matsuoka, M.1    Kato, J.2    Fisher, R.3    Morgan, D.O.4    Sherr, C.J.5
  • 19
    • 0027471557 scopus 로고
    • Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15
    • Sebastian B, Kakizuka A, Hunter T 1993 Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15. Proc Natl Acad Sci USA 90:3521-3524
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3521-3524
    • Sebastian, B.1    Kakizuka, A.2    Hunter, T.3
  • 21
    • 0028918388 scopus 로고
    • Novel Ink4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
    • Hirai H, Roussel MF, Kato J-Y, Ashum RA, Sherr CJ 1995 Novel Ink4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol Cell Biol 15:2672-2681
    • (1995) Mol Cell Biol , vol.15 , pp. 2672-2681
    • Hirai, H.1    Roussel, M.F.2    Kato, J.-Y.3    Ashum, R.A.4    Sherr, C.J.5
  • 22
    • 0028168242 scopus 로고
    • INK4B is a potential effector of TGFβ-induced cell cycle arrest
    • INK4B is a potential effector of TGFβ-induced cell cycle arrest. Nature 371:257-261
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 23
    • 0027769876 scopus 로고
    • A new regulatory motif in the cell cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D 1993 A new regulatory motif in the cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 366:704-707
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 25
    • 0027731971 scopus 로고
    • Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
    • Gu Y, Turck CW, Morgan DO 1993 Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 366:707-710
    • (1993) Nature , vol.366 , pp. 707-710
    • Gu, Y.1    Turck, C.W.2    Morgan, D.O.3
  • 26
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ 1993 The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 27
    • 0028988158 scopus 로고
    • Kip2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
    • Kip2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev 9:639-649
    • (1995) Genes Dev , vol.9 , pp. 639-649
    • Lee, M.-H.1    Reynisdottir, I.2    Massague, J.3
  • 29
    • 0028342664 scopus 로고
    • Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
    • Noda A, Ning Y, Venable SF, Pereira-Smith OM, Smith JR 1994 Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 211:90-98
    • (1994) Exp Cell Res , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 31
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21
    • Toyoshima H, Hunter T 1994 p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21. Cell 78:67-74
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 33
    • 0028270189 scopus 로고
    • Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase
    • Kato J-Y, Matsaaki M, Strom DK, Sherr CJ 1994 Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase. Mol Cell Biol 14:2713-2721
    • (1994) Mol Cell Biol , vol.14 , pp. 2713-2721
    • Kato, J.-Y.1    Matsaaki, M.2    Strom, D.K.3    Sherr, C.J.4
  • 36
  • 37
    • 0026537277 scopus 로고
    • The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F
    • Hiebert SW, Chellappan SP, Horowitz JM, Nevins JR 1992 The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev 6:177-185
    • (1992) Genes Dev , vol.6 , pp. 177-185
    • Hiebert, S.W.1    Chellappan, S.P.2    Horowitz, J.M.3    Nevins, J.R.4
  • 38
    • 0026530730 scopus 로고
    • The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle related manner
    • Shirodkar S, Ewen M, DeCaprio JA, Morgan J, Livingston DM, Chittenden T 1992 The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle related manner. Cell 68:157-166
    • (1992) Cell , vol.68 , pp. 157-166
    • Shirodkar, S.1    Ewen, M.2    DeCaprio, J.A.3    Morgan, J.4    Livingston, D.M.5    Chittenden, T.6
  • 39
    • 0026636908 scopus 로고
    • Retinoblastoma protein switches the E2F site from a positive to a negative element
    • Weintraub SJ, Prater CA, Dean DC 1992 Retinoblastoma protein switches the E2F site from a positive to a negative element. Nature 358:259-261
    • (1992) Nature , vol.358 , pp. 259-261
    • Weintraub, S.J.1    Prater, C.A.2    Dean, D.C.3
  • 40
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA 1995 The retinoblastoma protein and cell cycle control. Cell 81:323-330
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 41
    • 0025831974 scopus 로고
    • Evidence that the G1 -S and the G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes
    • Fang F, Newport J 1991 Evidence that the G1 -S and the G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes. Cell 66:731-742
    • (1991) Cell , vol.66 , pp. 731-742
    • Fang, F.1    Newport, J.2
  • 42
    • 0027298902 scopus 로고
    • The cdk2 kinase is required for the G1-to-S phase transition in mammalian cells
    • Tsai L-H, Lees E, Faha B, Harlow E, Riabowol K 1993 The cdk2 kinase is required for the G1-to-S phase transition in mammalian cells. Oncogene 8:1593-1602
    • (1993) Oncogene , vol.8 , pp. 1593-1602
    • Tsai, L.-H.1    Lees, E.2    Faha, B.3    Harlow, E.4    Riabowol, K.5
  • 43
    • 0030061451 scopus 로고    scopus 로고
    • Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity
    • Guadagno TM, Newport JW 1996 Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity. Cell 84:73-82
    • (1996) Cell , vol.84 , pp. 73-82
    • Guadagno, T.M.1    Newport, J.W.2
  • 44
    • 0025218464 scopus 로고
    • Retinoid modulation of estradiol-stimulated growth and of protein synthesis and secretion in human breast carcinoma cells
    • Fontana JA, Mezu AB, Cooper BN, Miranda D 1990 Retinoid modulation of estradiol-stimulated growth and of protein synthesis and secretion in human breast carcinoma cells. Cancer Res 50:1997-2002
    • (1990) Cancer Res , vol.50 , pp. 1997-2002
    • Fontana, J.A.1    Mezu, A.B.2    Cooper, B.N.3    Miranda, D.4
  • 45
    • 0019192020 scopus 로고
    • The effects of retinoids on proliferative capacities and macromolecular synthesis in human breast cancer MCF-7 cells
    • Ueda H, Takenawa T, Millan JC, Gesell MS, Brandes D 1980 The effects of retinoids on proliferative capacities and macromolecular synthesis in human breast cancer MCF-7 cells. Cancer 46:2203-2209
    • (1980) Cancer , vol.46 , pp. 2203-2209
    • Ueda, H.1    Takenawa, T.2    Millan, J.C.3    Gesell, M.S.4    Brandes, D.5
  • 46
    • 0026634031 scopus 로고
    • Retinoid antagonism of estrogen-responsive transforming growth factor α and pS2 gene expression in breast carcinoma cells
    • Fontana JA, Nervi C, Shao ZM, Jetten AM 1992 Retinoid antagonism of estrogen-responsive transforming growth factor α and pS2 gene expression in breast carcinoma cells. Cancer Res 52:3938-3945
    • (1992) Cancer Res , vol.52 , pp. 3938-3945
    • Fontana, J.A.1    Nervi, C.2    Shao, Z.M.3    Jetten, A.M.4
  • 48
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGFβ
    • Reynisdottir I, Polyak K, Iavarone A, Massague J 1995 Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGFβ. Genes Dev 9:1831-1845
    • (1995) Genes Dev , vol.9 , pp. 1831-1845
    • Reynisdottir, I.1    Polyak, K.2    Iavarone, A.3    Massague, J.4
  • 49
    • 0028227197 scopus 로고
    • A novel inhibitor of cyclin-cdk activity detected in transforming growth factor β-arrested epithelial cells
    • Slingerland JM, Hengst L, Pan C-H, Alexander D, Stampfer MR, Reed SI 1994 A novel inhibitor of cyclin-cdk activity detected in transforming growth factor β-arrested epithelial cells. Mol Cell Biol 14:3683-3694
    • (1994) Mol Cell Biol , vol.14 , pp. 3683-3694
    • Slingerland, J.M.1    Hengst, L.2    Pan, C.-H.3    Alexander, D.4    Stampfer, M.R.5    Reed, S.I.6
  • 51
    • 0028786916 scopus 로고
    • Antiestrogen inhibition of cell cycle progression in breast cancer cells is associated with inhibition of cyclin-dependent kinase activity and decreased retinoblastoma protein phosphorylation
    • Watts CKW, Brady A, Sarcevic B, deFazio A, Musgrove EA, Sutherland RL 1995 Antiestrogen inhibition of cell cycle progression in breast cancer cells is associated with inhibition of cyclin-dependent kinase activity and decreased retinoblastoma protein phosphorylation. Mol Endocrinol 9:1804-1813
    • (1995) Mol Endocrinol , vol.9 , pp. 1804-1813
    • Watts, C.K.W.1    Brady, A.2    Sarcevic, B.3    DeFazio, A.4    Musgrove, E.A.5    Sutherland, R.L.6
  • 52
    • 0028128954 scopus 로고
    • Differential expression and regulation of cyclin D1 protein in normal and tumor human cells: Association with Cdk4 is required for cyclin D1 function in G1 progression
    • Tam SW, Theodoras AM, Shay JW, Draetta GF, Pagano M 1994 Differential expression and regulation of cyclin D1 protein in normal and tumor human cells: association with Cdk4 is required for cyclin D1 function in G1 progression. Oncogene 9:2663-2674
    • (1994) Oncogene , vol.9 , pp. 2663-2674
    • Tam, S.W.1    Theodoras, A.M.2    Shay, J.W.3    Draetta, G.F.4    Pagano, M.5
  • 53
    • 0030046296 scopus 로고    scopus 로고
    • Differential effects of retinoids and antiestrogens on cell cycle progression and cell cycle regulatory genes in human breast cancer cells
    • Wilcken NRC, Sarcevic B, Musgrove EA, Sutherland RL 1996 Differential effects of retinoids and antiestrogens on cell cycle progression and cell cycle regulatory genes in human breast cancer cells. Cell Growth Differ 7:65-74
    • (1996) Cell Growth Differ , vol.7 , pp. 65-74
    • Wilcken, N.R.C.1    Sarcevic, B.2    Musgrove, E.A.3    Sutherland, R.L.4
  • 54
    • 0029670838 scopus 로고    scopus 로고
    • Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2
    • Gorospe M, Lui Y, Xu Q, Chrest FJ, Holbrook NJ 1996 Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2. Mol Cell Biol 16:762-770
    • (1996) Mol Cell Biol , vol.16 , pp. 762-770
    • Gorospe, M.1    Lui, Y.2    Xu, Q.3    Chrest, F.J.4    Holbrook, N.J.5
  • 57
    • 0029147732 scopus 로고
    • Both p16 and p21 families of cyclin-dependent kinase (cdk) inhibitors block the phosphorylation of cyclin dependent kinases by the cdk-activating kinase
    • Aprelikova O, Xiong X, Lui ET 1995 Both p16 and p21 families of cyclin-dependent kinase (cdk) inhibitors block the phosphorylation of cyclin dependent kinases by the cdk-activating kinase. J Biol Chem 270: 18195-18197
    • (1995) J Biol Chem , vol.270 , pp. 18195-18197
    • Aprelikova, O.1    Xiong, X.2    Lui, E.T.3
  • 58
    • 0030012189 scopus 로고    scopus 로고
    • Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells
    • Foster JS, Wimalasena J 1996 Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells. Mol Endocrinol 10:488-498
    • (1996) Mol Endocrinol , vol.10 , pp. 488-498
    • Foster, J.S.1    Wimalasena, J.2
  • 61
    • 0027471557 scopus 로고
    • Cdc25M2 activation of cyclin dependent kinases by dephosphorylation of threonin-14 and tyrosine-15
    • Sebastian B, Kakizuka A, Hunter T 1993 Cdc25M2 activation of cyclin dependent kinases by dephosphorylation of threonin-14 and tyrosine-15. Proc Natl Acad Sci USA 90:3521-3524
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3521-3524
    • Sebastian, B.1    Kakizuka, A.2    Hunter, T.3
  • 62
    • 0025695138 scopus 로고
    • Okadaic acid, a potent inhibitor of type I and type 2A protein phosphatases, activates ada2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells
    • Yamashita K, Yasuda H, Pines J, Yasumoto K, Nishitani H, Ohtsubo M, Hunter T, Sugimura T, Nishimoto T 1990 Okadaic acid, a potent inhibitor of type I and type 2A protein phosphatases, activates ada2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells. EMBO J 9:4331-4338
    • (1990) EMBO J , vol.9 , pp. 4331-4338
    • Yamashita, K.1    Yasuda, H.2    Pines, J.3    Yasumoto, K.4    Nishitani, H.5    Ohtsubo, M.6    Hunter, T.7    Sugimura, T.8    Nishimoto, T.9
  • 64
    • 0028019279 scopus 로고
    • Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA binding activity of E2F/DP-1 by phosphorylation
    • Xu M, Sheppard K-A, Peng C-Y, Yee AS, Piwnica-Worms H 1994 Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA binding activity of E2F/DP-1 by phosphorylation. Mol Cell Biol 14:8420-8431
    • (1994) Mol Cell Biol , vol.14 , pp. 8420-8431
    • Xu, M.1    Sheppard, K.-A.2    Peng, C.-Y.3    Yee, A.S.4    Piwnica-Worms, H.5
  • 65
    • 0027936686 scopus 로고
    • Differential regulation of E2F transactivation by cyclin/cdk2 complexes
    • Dynlacht BD, Flores O, Lees JA, Harlow E 1994 Differential regulation of E2F transactivation by cyclin/cdk2 complexes. Genes Dev 8:1771-1786
    • (1994) Genes Dev , vol.8 , pp. 1771-1786
    • Dynlacht, B.D.1    Flores, O.2    Lees, J.A.3    Harlow, E.4
  • 66
    • 0029559027 scopus 로고
    • Cyclin-A kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint
    • Krek W, Xu G, Livingston DM 1995 Cyclin-A kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell 83:1149-1158
    • (1995) Cell , vol.83 , pp. 1149-1158
    • Krek, W.1    Xu, G.2    Livingston, D.M.3
  • 67
    • 0019023345 scopus 로고
    • Purification of mouse immunoglobulin heavy chain messenger RNAs from total myeloma tumor RNA
    • Auffray C, Rougeon F 1980 Purification of mouse immunoglobulin heavy chain messenger RNAs from total myeloma tumor RNA. Eur J Biochem 107:303-314
    • (1980) Eur J Biochem , vol.107 , pp. 303-314
    • Auffray, C.1    Rougeon, F.2
  • 68
    • 6844261978 scopus 로고
    • A highly porous SDS gel electrophoresis system: A versatile technique for protein structure-function study
    • Doucet JP, Murphy BJ, Tuana BS 1993 A highly porous SDS gel electrophoresis system: a versatile technique for protein structure-function study. Methods Pharmacol 7:237-254
    • (1993) Methods Pharmacol , vol.7 , pp. 237-254
    • Doucet, J.P.1    Murphy, B.J.2    Tuana, B.S.3
  • 69
    • 0028089946 scopus 로고
    • Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)
    • Tassan JP, Schultz SJ, Bartek J, Nigg EA 1994 Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase). J Cell Biol 127:467-478
    • (1994) J Cell Biol , vol.127 , pp. 467-478
    • Tassan, J.P.1    Schultz, S.J.2    Bartek, J.3    Nigg, E.A.4


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