Evaluation of cytotoxic T-lymphocyte responses in human and nonhuman primate subjects infected with human immunodeficiency virus type 1 or simian/human immunodeficiency virus

Journal of Virology

Volumn 75, Issue 1, 2001, Pages 73-82

  Fu, T M ^a   Freed, D C ^a   Trigona, W L ^a   Guan, L ^a   Zhu, L ^a   Long, R ^a   Persaud, N V ^a   Manson, K ^a   Dubey, S ^a   Shiver, J W ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CHIMPANZEE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; EFFECTOR CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION CONTROL; LYMPHOCYTE CULTURE; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS INFECTION; VIRUS REPLICATION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; HIV-1; HUMANS; INTERLEUKIN-7; MACACA MULATTA; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0034747792     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.1.73-82.2001     Document Type: Article

References (43)

1. Characterization of the peptide binding motif of a rhesus MHC class I molecule (Mamu-A°01) that binds an immunodominant CTL epitope from simian immunodeficiency virus
2. Phenotypic analysis of antigen-specific T lymphocytes
3. MHC class I-associated peptides produced from endogenous gene products with vastly different efficiencies
4. Recombinant vaccinia viruses as vectors for studying T lymphocyte specificity and function
5. MHC restriction in three dimensions: A view of T cell receptor/ligand interactions
6. + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
7. Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
8. The evaluation of limiting dilution assays
9. Replicationdefective canarypox (ALVAC) vectors effectively activate anti-human immunodeficiency virus-1 cytotoxic T lymphocytes present in infected patients: Implications for antigen-specific immunotherapy
10. Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers
11. An endoplasmic reticulum-targeting signal sequence enhances the immunogenicity of an immunorecessive simian virus 40 large T antigen cytotoxic T-lymphocyte epitope
12. Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques
13. An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex
14. Use of recombinant vaccinia to restimulate antigen specific human peripheral blood cytotoxic T lymphocytes
15. MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation
16. Cytotoxic T lymphocytes in asymptomatic long-term nonprogressing HIV-1 infection: Breadth and specificity of the response and relation to in vivo viral quasispecies in a person with prolonged infection and low viral load
17. Toward an undrstanding of the correlates of protective immunity to HIV infection
18. Dramatic rise in plasma viremia after CD8+ T cell depletion in simian immunodeficiency virus-infected macaques
19. Induction of vigorous cytotoxic Tlymphocyte responses by live attenuated simian immunodeficieney virus
20. Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses
21. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity
22. T cell receptor usage and fine specificity of human immunodeficiency virus 1-specific cytotoxic T lymphocyte clones: Analysis of quasispecies recognition reveals a dominant response directed against a minor in vivo variant
23. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
24. Emergence of CTL coincides with clearance of virus during primary simian immunodeficiency virus infection in rhesus monkeys
25. Rapid effector function in CD8+ memory T cells
26. From TCR engagement to T cell activation: A kinetic view of T cell behavior
27. Progress in the development of an HIV-1 vaccine
28. Utility of SHIV for testing HIV-1 vaccine candidates in macaques
29. A novel method for detection and ex vivo expansion of HIV type 1-specific cytolytic T lymphocytes
30. Escape of human immunodeficiency virus from immune control
31. Definition of an epitope and MHC class I molecule recognized by gag-specific cytotoxic T lymphocytes in SIVmac-infected rhesus monkeys
32. Cytotoxic-T-cell responses, viral load, and disease progression in early human immunodeficiency virus type 1 infection
33. Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA
34. Mechanisms of MHC class I-restricted antigen processing
35. Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: A predominant gag-specific response is associated with nonprogressive infection
36. A single specific amino acid residue in peptide antigens is sufficient to activate memory CTL: Potential role of cross-reactive peptides in memory T cell maintenance
37. Vaccine protection against a heterologous, non-syncytium-inducing, primary human immunodeficiency virus
38. Control of viremia in simian immnnodeficiency virus infection by CD8+ lymphocytes
39. Extracellular processing of peptide antigens that bind class I major histocompatibility molecules
40. Definition of human immunodeficiency virus type 1 gp120 and gp41 cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I alleles in simian-human immunodeficiency virus-infected rhesus monkeys
41. Human immunodeficiency virus type 1 envelope glycoprotein-specific cytotoxic T lymphocytes in simian-human immunodeficiency virus-infected rhesus monkeys
42. Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes
43. Immnnodominance in major histocompatibility complex class I-restricted T lymphocyte responses