The cholesterol-lowering drug Probucol increases apolipoprotein E production in the hippocampus of aged rats: Implications for Alzheimer's disease

Neuroscience

Volumn 121, Issue 1, 2003, Pages 99-110

  Champagne, D ^a,b   Pearson, D ^a   Dea, D ^a   Rochford, J ^a,b   Poirier, J ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

3 hydroxy 3 methylglutaryl coenzyme A reductase; Astrocytes; Glial fibrillary acidic protein; LDL receptor family; Statin; Synaptic plasticity

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; GLIAL FIBRILLARY ACIDIC PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; PROBUCOL; SYNAPTOPHYSIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25;

AGED; AGING; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CHOLESTEROL SYNTHESIS; COHORT ANALYSIS; CONTROLLED STUDY; DENDRITIC CELL; DRUG EFFICACY; DRUG MECHANISM; GLIA CELL; HIPPOCAMPUS; LIPOPROTEIN SYNTHESIS; MALE; NERVE CELL PLASTICITY; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; SYNAPTOGENESIS;

EID: 0142028254     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(03)00361-0     Document Type: Article

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