-
1
-
-
0023447098
-
Cellular localization of the multidrug resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut, F., Tsuruo, T., Hamada, H., Gottesman, M. M., Pastan, I. and Willingham, M. C.: Cellular localization of the multidrug resistance gene product P-glycoprotein in normal human tissues. Proc. Natl. Acad. Sci. USA., 84: 7735-7738 (1987).
-
(1987)
Proc. Natl. Acad. Sci. USA.
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
2
-
-
0034724324
-
Functional polymorphisms of human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer, S., Burk, O., von Richter, O., Arnold, H. P., Brockmöller, J., Johne, A., Cascorbi, I., Gerloff, T., Roots, I., Eichelbaum, M. and Brinkmann, U.: Functional polymorphisms of human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. USA., 97: 3473-3478 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA.
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
von Richter, O.3
Arnold, H.P.4
Brockmöller, J.5
Johne, A.6
Cascorbi, I.7
Gerloff, T.8
Roots, I.9
Eichelbaum, M.10
Brinkmann, U.11
-
3
-
-
0034971274
-
The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56 + natural killer cells
-
Hitzl, M., Drescher, S., van der Kuip, H., Schaffeler, E., Fisher, J., Schwab, M., Eichelbaum, M. and Fromm, M.F.: The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56 + natural killer cells. Pharmacogenetics., 11: 293-298 (2001).
-
(2001)
Pharmacogenetics.
, vol.11
, pp. 293-298
-
-
Hitzl, M.1
Drescher, S.2
van der Kuip, H.3
Schaffeler, E.4
Fisher, J.5
Schwab, M.6
Eichelbaum, M.7
Fromm, M.F.8
-
4
-
-
0034997034
-
Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene
-
Tanabe, M., Ieiri, I., Nagata, N., Inoue, K., Ito, S., Kanamori, Y., Takahashi, M., Kuruta, Y., Kigawa, J., Higuchi, S., Terakawa, N. and Otsubo, K.: Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene. J. Pharmacol. Exp. Ther., 297: 1137-1143 (2001).
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.297
, pp. 1137-1143
-
-
Tanabe, M.1
Ieiri, I.2
Nagata, N.3
Inoue, K.4
Ito, S.5
Kanamori, Y.6
Takahashi, M.7
Kuruta, Y.8
Kigawa, J.9
Higuchi, S.10
Terakawa, N.11
-
5
-
-
0036224114
-
Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects
-
Nakamura, T., Sakaeda, T., Horinouchi, M., Tamura, T., Aoyama, N., Shirakawa, T., Matsuo, M., Kasuga, M. and Okumura, K.: Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects. Clin. Pharmacol. Ther., 71: 297-303 (2002).
-
(2002)
Clin. Pharmacol. Ther.
, vol.71
, pp. 297-303
-
-
Nakamura, T.1
Sakaeda, T.2
Horinouchi, M.3
Tamura, T.4
Aoyama, N.5
Shirakawa, T.6
Matsuo, M.7
Kasuga, M.8
Okumura, K.9
-
6
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
Kim, R. B., Leake, B. F., Choo, E. F., Dresser, G. K., Kubba, S. V., Schwarz, U. I., Taylor, A., Xie, H.-G., McKinsey, J., Zhou, S., Lan, L.-B., Schuetz, J. D., Schuetz, E. G. and Wilkinson, G. R.: Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin. Pharmacol. Ther., 70: 189-199 (2001).
-
(2001)
Clin. Pharmacol. Ther.
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
Dresser, G.K.4
Kubba, S.V.5
Schwarz, U.I.6
Taylor, A.7
Xie, H.-G.8
McKinsey, J.9
Zhou, S.10
Lan, L.-B.11
Schuetz, J.D.12
Schuetz, E.G.13
Wilkinson, G.R.14
-
7
-
-
0034771497
-
MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects
-
Sakaeda, T., Nakamura, T., Horinouchi, M., Kakumoto, M., Ohmoto, N., Sakai, T., Morita, Y., Tamura, T., Aoyama, N., Hirai, M., Kasuga, M. and Okumura, K.: MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects. Pharm. Res., 18: 1400-1404 (2001).
-
(2001)
Pharm. Res.
, vol.18
, pp. 1400-1404
-
-
Sakaeda, T.1
Nakamura, T.2
Horinouchi, M.3
Kakumoto, M.4
Ohmoto, N.5
Sakai, T.6
Morita, Y.7
Tamura, T.8
Aoyama, N.9
Hirai, M.10
Kasuga, M.11
Okumura, K.12
-
8
-
-
0025191307
-
Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins
-
Chen, C.-J., Clark, D., Ueda, K., Pastan, I., Gottesman, M. M. and Roninson, I. B.: Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins. J. Biol. Chem., 265: 506-514 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 506-514
-
-
Chen, C.-J.1
Clark, D.2
Ueda, K.3
Pastan, I.4
Gottesman, M.M.5
Roninson, I.B.6
-
9
-
-
0028857917
-
Drug-stimulated ATPase activity of a deletion mutant of the human multidrug-resistance protein (MDR1)
-
Welker, E., Szabo, K., Hollo, Z., Muller, M., Sarkadi, B. and Varadi, A.: Drug-stimulated ATPase activity of a deletion mutant of the human multidrug-resistance protein (MDR1). Biochem. Biophys. Res. Commun., 216: 602-609 (1995).
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.216
, pp. 602-609
-
-
Welker, E.1
Szabo, K.2
Hollo, Z.3
Muller, M.4
Sarkadi, B.5
Varadi, A.6
-
10
-
-
0027997698
-
Mutations to amino acid located in predicted transmembrane segment 6 (TM6) modulate the activity and substrate specificity of human P-glycoprotein
-
Loo, T. W. and Clarke, D. M.: Mutations to amino acid located in predicted transmembrane segment 6 (TM6) modulate the activity and substrate specificity of human P-glycoprotein. Biochemistry., 33: 14049-14057 (1994).
-
(1994)
Biochemistry.
, vol.33
, pp. 14049-14057
-
-
Loo, T.W.1
Clarke, D.M.2
-
11
-
-
0030796990
-
Amino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity
-
Taguchi, Y., Morishima, M., Komano, T. and Ueda, K.: Amino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity. FEBSLett., 413: 142-146 (1997).
-
(1997)
FEBSLett.
, vol.413
, pp. 142-146
-
-
Taguchi, Y.1
Morishima, M.2
Komano, T.3
Ueda, K.4
-
12
-
-
0034096096
-
Chemoprotection of hematopoietic cells by a mutant P-glycoprotein resistant to a potent chemosen-sitizer of multidrug-resistant cancers
-
Hafkemeyer, P., Licht, T., Pastan, I. and Gottesman, M. M.: Chemoprotection of hematopoietic cells by a mutant P-glycoprotein resistant to a potent chemosen-sitizer of multidrug-resistant cancers. Hum. Gene. Ther., 11: 555-565 (2000).
-
(2000)
Hum. Gene. Ther.
, vol.11
, pp. 555-565
-
-
Hafkemeyer, P.1
Licht, T.2
Pastan, I.3
Gottesman, M.M.4
|