Application of the "VARICOL" process to the separation of the isomers of the SB-553261 racemate

Journal of Chromatography A

Volumn 947, Issue 1, 2002, Pages 59-68

  Ludemann Hombourger, O ^a   Pigorini, G ^a   Nicoud, R M ^a   Ross, D S ^b   Terfloth, G ^c  

^a NOVASEP SAS   (France)

^b GLAXOSMITHKLINE   (United Kingdom)

^c NONE   (United States)

Author keywords

Enantiomer separation; Multi column system; Preparative chromatography; SB 553261; Simulated moving bed; VARICOL process

Indexed keywords

ISOMERS; SEPARATION;

OPTICAL ISOMERS;

CHROMATOGRAPHIC ANALYSIS;

DRUG; SB 553261; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHROMATOGRAPHY; INTERMETHOD COMPARISON; ISOMER; PRIORITY JOURNAL; RACEMIC MIXTURE; RELIABILITY;

CHROMATOGRAPHY; HETEROCYCLIC COMPOUNDS, 2-RING; STEREOISOMERISM;

EID: 0037083064     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(01)01568-0     Document Type: Article

References (10)

1. The VARICOL process: A new multicolumn continuous chromatographic process
2. Complete design of a simulated moving bed
3. Adsorption isotherms: Experimental determination and application to preparative chromatography
4. Design and optimisation of a simulated moving bed unit: Role of deviations from equilibrium theory