Proteinuria and tubulointerstitial injury: The causative factors for the progression of renal diseases

Contributions to Nephrology

Volumn 139, Issue , 2003, Pages 20-31

  Matsuo, Seiichi ^a   Marita, Yoshiki ^a   Maruyama, Shoichi ^a   Manchang, Liu ^a   Yuzawa, Yukio ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; BIOLOGICAL MODEL; DISEASE COURSE; DISEASE MODEL; HUMAN; INJURY; INTERSTITIAL NEPHRITIS; KIDNEY DISEASE; KIDNEY TUBULE; PATHOLOGY; PATHOPHYSIOLOGY; PROTEINURIA; REVIEW;

ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; HUMANS; KIDNEY DISEASES; KIDNEY TUBULES; MODELS, BIOLOGICAL; NEPHRITIS, INTERSTITIAL; PROTEINURIA;

EID: 0141888078     PISSN: 03025144     EISSN: None     Source Type: Book Series    
DOI: 10.1159/000071734     Document Type: Article

References (70)

1. Schainuck LI, Striker GE, Cutler RE, Benditt EP: Structural-functional correlations in renal disease. II. The correlations. Hum Pathol 1970;1:631-640.
2. Bohle A, Wehrmann M, Bogenschutz O, Batz C, Vogl W, Schmitt H, Muller CA, Muller GA: The long-term prognosis of the primary glomerulonephritis. A morphological and clinical analysis of 1,747 cases. Pathol Res Pract 1992;188:908-924.
3. Nath KA: Tubulointerstitial changes as a major determinant in the progression of renal damage. Am J Kidney Dis 1992;20:1-17.
4. Eddy AA: Experimental insights into the tubulointerstitial disease accompanying primary glomerular lesions. J Am Soc Nephrol 1994;5:1273-1287.
5. Burton C, Harris KPG: The role of proteinuria in the progression of chronic renal failure. Am J Kidney Dis 1996;27:765-775.
6. Remuzzi G, Ruggenenti P, Benigni A: Understanding the nature of renal disease progression. Kidney Int 1997;51:2-15.
7. Bruzzi I, Benigni A, Remuzzi G: Role of increased glomerular protein traffic in the progression of renal failure. Kidney Int 1997;52(suppl 62):29-31.
8. Peterson JC, Adler S, Burkart JM, Greene T, Hebert LA, Hunsicker L, King AJ, Klahr S, Massry SG, Seifter JL, for the MDRD Study Group: Blood pressure control, proteinuria and the progression of renal disease. Ann Intern Med 1995;123:754-762.
9. Ruggenenti P, Perna A, Mosconi L, Pisoni R, Remuzzi G, on behalf of the Gruppo Italino di Studi Epidemiologici in Nefrologi (GISEN): Urinary protein excretion rate is the best independent predictor of ESRF in non-diabetic proteinuric chronic nephropathies. Kidney Int 1998;53:1209-1216.
10. Eddy AA, Michael AF: Acute tubulointerstitial nephritis associated with aminonucleoside nephrosis. Kidney Int 1988;33:14-23.
11. Eddy AA, McCulloch L, Liu E, Adams J: A relationship between proteinuria and acute tubulointerstitial disease in rats with experimental nephrotic syndrome. Am J Pathol 1991;138:1111-1123.
12. Eddy AA, Warren JS, Liu E, McCulloch L: Expression and function of monocyte chemoattractant protein-1 in experimental nephrotic syndrome. Clin Immunol Immunopathol 1996;78:140-151.
13. Pichler R, Giachelli CM, Lombardi D, Pippin J, Gordon K, Alpers CE, Schwartz SM, Johenson RJ: Tubulointerstitial disease in glomerulonephritis: Potential role of osteopontin (uropontin). Am J Pathol 1994;144:915-926.
14. Magil AB, Pichler RH, Johnson RJ: Osteopontin in chronic puromycin aminonucleoside nephrosis. J Am Soc Nephrol 1997;8:1383-1390.
15. Tang WW, Qi M, Warren JS, Van GY: Chemokine expression in experimental tubulointerstitial nephritis. J Immunol 1997;159:870-876.
16. Jones CL, Buch S, Post M, McCulloch L, Liu E, Eddy AA: Pathogenesis of interstitial fibrosis in chronic purine aminonucleoside nephrosis. Kidney Int 1991;40:1020-1031.
17. Eddy AA, Giachelli CM, McCulloch L, Liu E: Renal expression of genes that promote interstitial inflammation and fibrosis in rats with protein-overload proteinuria. Kidney Int 1995;47:1546-1557.
18. Thomas ME, Brunskill NJ, Harris KPG, Bailey E, Pringle JH, Furness PN, Walls J: Proteinuria induces tubular cell turnover: A potential mechanism for tubular atrophy. Kidney Int 1999;55:890-898.
19. 1, in glomerulosclerosis and interstitial fibrosis of adriamycin nephropathy. Kidney Int 1994;45:525-536.
20. Gomez-Chiarri M, Ortiz A, Gonzalez-Cuadrado S, Seron D, Emancipator SN, Hamilton TA, Barat A, Plaza JJ, Gonzalez E, Egido J: Interferon-inducible protein-10 is highly expressed in rats with experimental nephrosis. Am J Pathol 1996;148:301-311.
21. Rangen GK, Wang Y, Tay YC, Harris DCH: Inhibition of nuclear factor-κB activation reduces cortical tubulointerstitial injury in proteinuric rats. Kidney Int 1999;56:118-134.
22. Maack T, Park CH, Camargo MJF: Renal filtration, transport and metabolism of proteins; in Seldin DW, Giebisch G (eds): The Kidney: Physiology and Pathophysiology. New York, Raven Press, 1985, pp 1773-1803.
23. Eppel GA, Osicka TM, Pratt LM, Jablonski P, Howden B, Glasgow EF, Comper WD: The return of glomerular-filtered albumin to the rat renal vein. Kidney Int 1999;55:1861-1870.
24. Cui S, Verroust PJ, Moestrup SK, Christensen El: Megalin/gp330 mediates uptake of albumin in renal proximal tubule. Am J Physiol 1996;271:F900-F907.
25. Birn H, Fyfe JC, Jacobsen C, Mounier F, Verroust PJ, Orskov H, Willnow TE, Moestrup SK, Christensen El: Cubulin is an albumin-binding protein important for renal tubular albumin reabsorption. J Clin Invest 2000;105:1353-1361.
26. Kees-Folts D, Sadow JL, Schreiner GF: Tubular catabolism of albumin is associated with the release of an inflammatory lipid. Kidney Int 1994;45:1697-1709.
27. Thoms ME, Schreiner GF: Contribution of proteinuria to progressive renal injury: Consequences of tubular uptake of fatty acid bearing albumin. Am J Nephrol 1993;13:385-398.
28. Wang Y, Chen J, Chen L, Tay YC, Rangan GK, Harris DCH: Induction of monocyte chemoattractant protein-1 in proximal tubule cells by urinary protein. J Am Soc Nephrol 1997;8:1537-1545.
29. Wang Y, Rangan GK, Chen J, Tay YC, Wang Y, Harris DCH: Induction of monocyte chemoattractant protein-1 by nuclear factor-κB in proximal tubule cells. J Am Soc Nephrol 1999;10:1204-1213.
30. Zoja C, Morigi M, Figliuzzi M, Bruzzi I, Oldroyd S, Benigni A, Ronco P, Remuzzi G: Proximal tubular cell synthesis and secretion of endothelin-1 on challenge with albumin and other proteins. Am J Kidney Dis 1995;26:934-941.
31. Zoja C, Donadelli R, Colleoni S, Figliuzzi M, Bonazzola S, Morigi M, Remuzzi G: Protein overload stimulates RANTES production by proximal tubular cells depending on NF-κB activation. Kidney Int 1998;53:1608-1615.
32. Dixon R, Brunskill NJ: Activation of mitogenic pathways by albumin in kidney proximal tubule epithelial cells: Implications for the pathophysiology of proteinuric states. J Am Soc Nephrol 1999;10:1487-1497.
33. Sato K, Ullrich KJ: Serum-induced inhibition of isotonic fluid absorption by the kidney proximal tubule. I. Mechanism of inhibition. Biochim Biophys Acta 1974;343:609-614.
34. Sato K, Ullrich KJ: Serum-induced inhibition of isotonic fluid absorption by the kidney proximal tubule. II. Evidence that complement is involved. Biochim Biophys Acta 1974;343:182-187.
35. Camussi G, Rotunno M, Segoloni G, Brentjens JR, Andres GA: In vitro alternative pathway activation of complement by the brush border of proximal tubules of normal rat kidney. J Immunol 1982;128:1659-1663.
36. Camussi G, Stratta P, Mazzucco G, Gaido M, Tetta C, Casteollo R, Rotunno M, Vercellone A: In vivo localization of C3 on the brush border of proximal tubules of kidneys from nephrotic patients. Clin Nephrol 1985;23:134-141.
37. Ogrodowski JL, Herbert LE, Sedmak D, Cosio FG, Tamerius J, Kolb W: Measurement of SC5b-9 in urine patients with the nephrotic syndrome. Kidney Int 1991;40:1141-1147.
38. Pruchno CJ, Burns MW, Schulze M, Johnson RJ, Baker PJ, Couser WG: Urinary excretion of C5b-9 reflects disease activity in passive Heymann's nephritis. Kidney Int 1989;36:65-71.
39. Morita Y, Nomura A, Yuzawa Y, Nishikawa K, Hotta N, Shimizu F, Matsuo S: The role of complement in the pathogenesis of tubulointerstitial lesions in rat mesangial proliferative glomerulonephritis. J Am Soc Nephrol 1997;8:1363-1372.
40. Nomura A, Morita Y, Maruyama S, Hotta N, Nadai M, Wang L, Hasegawa T, Matsuo S: Role of complement in acute tubulointerstitial injury of rats with aminonucleoside nephrosis. Am J Pathol 1997;151:539-547.
41. Nangaku M, Pippin J, Couser WG: Complement membrane attack complex (C5b-9) mediates interstitial disease in experimental nephrotic syndrome. J Am Soc Nephrol 1999;10:2323-2331.
42. Hostetter MK, Gordon DL: Biochemistry of C3 and related thioester proteins in infection and inflammation. Rev Infect Dis 1987;9:97-109.
43. Ichida S, Yuzawa Y, Okada H, Yoshioka K, Matso S: Localization of the complement regulatory proteins in the normal human kidney. Kidney Int 1994;46:89-96.
44. Nath KA, Hostetter MK, Hostetter TH: Increased ammoniagenesis as a determinant of progressive renal injury. Am J Kidney Dis 1991;17:654-657.
45. Nath KA, Hostetter MK, Hostetter TH: Pathophysiology of chronic tubulointerstitial disease in rats. Interaction of dietary acid load, ammonia and complement component C3. J Clin Invest 1985;76:667-675.
46. Sacks SH, Zhou W, Sheerin N: Complement synthesis in the injured kidney: Does it have a role in immune complex glomerulonephritis? J Am Soc Nephrol 1996;7:2314-2319.
47. Sacks SH, Zhou W, Andrews PA, Hartley B: Endogenous complement C3 synthesis in immune complex nephritis. Lancet 1993;342:1273-1274.
48. Volanakis JE, Barnum SR, Guddens M, Galla JH: Renal filtration and catabolism of complement protein D. N Engl J Med 1985;312:395-399.
49. Morita Y, Ikeguchi H, Nakamura J, Hotta N, Yuzawa Y, Matsuo S: Complement activation products in the urine from proteinuric patients. J Am Soc Nephrol 2000;11:700-707.
50. Biancone L, David S, Pietra DV, Montrucchio G, Cambi V, Camussi G: Alternative pathway activation of complement by cultured human proximal tubular epithelial cells. Kidney Int 1994;45:451-460.
51. Tang S, Sheerin NS, Zhou W, Brown Z, Sacks SH: Apical proteins stimulate complement synthesis by cultured human proximal tubular epithelial cells. J Am Soc Nephrol 1999;10:69-76.
52. David S, Biancone L, Caserta C, Bussolati B, Cambi V, Camussi G: Alternative pathway complement activation induces proinflammatory activity in human proximal tubular epithelial cells. Nephrol Dial Transplant 1997;12:51-56.
53. Abbate M, Zoja C, Rottoli D, Corna D, Perico N, Bertani T, Remuzzi G: Antiproteinuric therapy while preventing the abnormal protein traffic in proximal tubule abrogates protein- and complement-dependent interstitial inflammation in experimental renal disease. J Am Soc Nephrol 1999;10:804-813.
54. Matsuo S, Morita Y, Mizuno M, Nishikawa K, Yuzawa Y: Proteinuria and damage to tubular cells - Is complement a culprit?. Nephrol Dial Transplant 1998;13:2723-2726.
55. Shah S: Role of iron in progressive renal disease. Am J Kidney Dis 2001;3(suppl):30-33.
56. Alfrey AC, Froment DH, Hammond WS: Role of iron in the tubulointerstitial injury in nephrotoxic serum nephritis. Kidney Int 1989;36:753-759.
57. Nankivell BJ, Tay YC, Boadle RA, Harris DC: Dietary protein alters tubular iron accumulation after partial nephrectomy. Kidney Int 1994;45:1006-1013.
58. Remuzzi A, Puntorieri S, Brugnetti B, Bertani T, Remuzzi G: Renoprotective effect of low iron diet and its consequence on glomerular hemodynamics. Kidney Int 1991;39:647-652.
59. Chen L, Wang Y, Tay YC, Harris DCH: Proteinuria and tubulointerstitial injury. Kidney Int Suppl 1997;61:60-62.
60. Ong ACM, Moorhead JF: Tubular lipidosis: Epiphenomenon or pathogenetic lesions in human renal disease? Kidney Int 1994;45:753-762.
61. Ong ACM, Jowett TP, Moorhead JF, Owen JS: Human high density lipoproteins stimulate endothelin-1 release by cultured human proximal tubular cells. Kidney Int 1994;46:1315-1321.
62. 3-kinase and ERK. Kidney Int 1999;56:2064-2075.
63. Frank J, Engler-Blum G, Rodemann HP, Muller GA: Human renal tubular cells as a cytokine source: PDGF-B, GM-CSF and IL-6 mRNA expression in vitro. Exp Nephrol 1993;1:26-35.
64. Frank J, Engler-Blum G, Rodemann HP, Muller GA: The role of interstitial cells in the progression of renal diseases. J Am Soc Nephrol 1992;2(suppl):198-205.
65. Hirschberg R: Bioactivity of glomerular ultrafiltrate during heavy proteinuria may contribute to renal tubulointerstitial lesions. Evidence for a role for insulin-like growth factor I. J Clin Invest 1996;97:116-124.
66. Wang SN, LaPage J, Hirschberg R: Role of glomerular ultrafiltration of growth factors in progressive interstitial fibrosis in diabetic nephropathy. Kidney Int 2000;57:1002-1014.
67. Ito Y, Goldschmeding R, Bende RJ, Claessen N, Chand M, Kleij L, Rabelink TJ, Weening JJ, Aten J: Kinetics of connective tissue growth factor expression during experimental proliferative glomerulonephritis. J Am Soc Nephrol 2001;12:472-484.
68. Ito Y, Aten J, Bende RJ, Osmar BS, Rabelink TJ, Weening JJ, Goldschmeding R: Expression of connective tissue growth factor in human renal fibrosis. Kidney Int 1998;53:853-861.
69. Wall J: Relationship between proteinuria and progressive renal disease. Am J Kidney Dis 2001;37(suppl 2):13-16.
70. Eddy AA: Role of cellular infiltrates in response to proteinuria. Am J Kidney Dis 2001;37(suppl 2):25-29.