Apical proteins stimulate complement synthesis by cultured human proximal tubular epithelial cells

Journal of the American Society of Nephrology

Volumn 10, Issue 1, 1999, Pages 69-76

  Tang, Sydney ^b   Sheerin, Neil S ^b   Zhou, Wuding ^b   Brown, Zarin ^b   Sacks, Steven H ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3; PLASMA PROTEIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; COMPLEMENT ACTIVATION; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; KIDNEY DISEASE; KIDNEY PROXIMAL TUBULE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTEINURIA;

EID: 0032951121     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Nath KA: Tubulointerstitial changes as a major determinant in the progression of renal damage. Am J Kidney Dis 20: 1-17, 1992
2. Bohle A, Strutz, F, Muller GA: On the pathogenesis of chronic renal failure in primary glomerulopathies: A view from the interstitium. Exp Nephrol 2: 205-210, 1994
3. Fine LG, Ong AC, Norman JT: Mechanisms of tubulo-interstitial injury in progressive renal diseases. Eur J Clin Invest 23: 259-265, 1993
4. Cameron JS: Tubular and interstitial factors in the progression of glomerulonephritis. Pediatr Nephrol 6: 292-303, 1992
5. Schainuck LI, Striker GE, Cutler RE, Benditt EP: Structural-functional correlations in renal disease. II. The correlations. Hum Pathol 1: 631-641, 1970
6. Bohle A, Mackensen-Haen S, von Gise H: Significance of tubulointerstitial changes in the renal cortex for the excretory function and concentration ability of the kidney: A morphometric contribution. Am J Nephrol 7: 421-433, 1987
7. Risdon RA, Sloper JC, De Wardener HE: Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis. Lancet 2: 363-366, 1968
8. Burton CJ, Combe C, Walls J, Harris KP: Fibronectin production by human tubular cells: The effect of apical protein. Kidney Int 50: 760-767, 1996
9. Border WA, Ruoslahti E: Transforming growth factor-beta in disease: The dark side of tissue repair. J Clin Invest 90: 1-7, 1992
10. Nomura A, Morita Y, Maruyama S, Hotta N, Nadai M, Wang L, Hasegawa T, Matsuo S: Role of complement in acute tubulointerstitial injury of rats with aminonucleoside nephrosis. Am J Pathol 151: 539-547, 1997
11. Biancone L, David S, Della PV, Montrucchio G, Cambi V, Camussi G: Alternative pathway activation of complement by cultured human proximal tubular epithelial cells. Kidney Int 45: 451-460, 1994
12. David S, Biancone L, Caserta C, Bussolati B, Cambi V, Camussi G: Alternative pathway complement activation induces proinflammatory activity in human proximal tubular epithelial cells. Nephrol Dial Transplant 12: 51-56, 1997
13. Brooimans RA, Stegmann AP, van Dorp WT, van der Ark AA, van der Woude FJ, van Es LA, Daha MR: Interleukin 2 mediates stimulation of complement C3 biosynthesis in human proximal tubular epithelial cells. J Clin Invest 88: 379-384, 1991
14. Seelen MA, Brooimans RA, van der Woude FJ, van Es LA, Daha MR: IFN-gamma mediates stimulation of complement C4 biosynthesis in human proximal tubular epithelial cells. Kidney Int 44: 50-57, 1993
15. Witte DP, Welch TR, Beischel LS: Detection and cellular localization of human C4 gene expression in the renal tubular epithelial cells and other extrahepatic epithelial sources. Am J Pathol 139: 717-724, 1991
16. Andrews PA, Finn JE, Lloyd CM, Zhou W, Mathieson PW, Sacks SH: Expression and tissue localization of donor-specific complement C3 synthesized in human renal allografts. Eur J Immunol 25: 1087-1093, 1995
17. Zhou W, Andrews PA, Wang Y, Wolff J, Pratt J, Hartley BR, Verroust P, Sacks SH: Evidence for increased synthesis of complement C4 in the renal epithelium of rats with passive Heymann nephritis. J Am Soc Nephrol 8: 214-222, 1997
18. Welch TR, Beischel LS, Witte DP: Differential expression of complement C3 and C4 in the human kidney. J Clin Invest 92: 1451-1458, 1993
19. Oren R, Laufer J, Goldberg I, Kopolovic J, Waldherr R, Passwell JH: C3, C4, factor B and HLA-DR alpha mRNA expression in renal biopsy specimens from patients with IgA nephropathy. Immunology 86: 575-583, 1995
20. Passwell J, Schreiner GF, Nonaka M, Beuscher HU, Colten HR: Local extrahepatic expression of complement genes C3, factor B, C2, and C4 is increased in murine lupus nephritis. J Clin Invest 2: 1676-1684, 1988
21. Phillips AO, Steadman R, Topley N, Williams JD: Elevated D-glucose concentrations modulate TGF-beta 1 synthesis by human cultured renal proximal tubular cells. The permissive role of platelet-derived growth factor. Am J Pathol 147: 362-374, 1995
22. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987
23. de Bruijn MH, Fey GH: Human complement component C3: cDNA coding sequence and derived primary structure. Proc Natl Acad Sci USA 82: 708-712, 1985
24. Ponte P, Ng SY, Engel J, Gunning P, Kedes L: Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA. Nucleic Acids Res 12: 1687-1696, 1984
25. Sacks S, Zhou W, Campbell RD, Martin J: C3 and C4 gene expression and interferon-gamma-mediated regulation in human glomerular mesangial cells. Clin Exp Immunol 93: 411-417, 1993
26. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970
27. Sacks SH, Zhou W, Sheerin NS: Complement synthesis in the injured kidney: Does it have a role in immune complex glomerulonephritis? J Am Soc Nephrol 7: 2314-2319, 1996
28. Cameron JS, Turner DR, Ogg CS, Chantler C, Williams DG: The long-term prognosis of patients with focal segmental glomerulosclerosis. Clin Nephrol 10: 213-218, 1978
29. Cameron JS, Turner DR, Heaton J, Williams DG, Ogg CS, Chantler C, Haycock GB, Hicks J: Idiopathic mesangiocapillary glomerulonephritis: Comparison of types I and II in children and adults and long-term prognosis. Am J Med 74: 175-192, 1983
30. D'Amico G, Minetti L, Ponticelli C, Fellin G, Ferrario F, Barbiano di Belgioioso G, Imbasciati E, Ragni A, Bertoli S, Fogazzi G: Prognostic indicators in idiopathic IgA mesangial nephropathy. Q J Med 59: 363-378, 1986
31. Erwin DT, Donadio JVJ, Holley KE: The clinical course of idiopathic membranous nephropathy. Mayo Clin Proc 48: 697-712, 1973
32. Eddy AA, McCulloch L, Liu E, Adams J: A relationship between proteinuria and acute tubulointerstitial disease in rats with experimental nephrotic syndrome. Am J Pathol 138: 1111-1123, 1991
33. Eddy AA: Interstitial nephritis induced by protein-overload proteinuria. Am J Pathol 135: 719-733, 1989
34. Morita Y, Nomura A, Yuzawa Y, Nishikawa K, Hotta N, Shimizu F, Matsuo S: The role of complement in the pathogenesis of tubulointerstitial lesions in rat mesangial proliferative glomerulonephritis. J Am Soc Nephrol 8: 1363-1372, 1997
35. Camussi G, Rotunno M, Segoloni G, Brentjens JR, Andres GA: In vitro alternative pathway activation of complement by the brush border of proximal tubules of normal rat kidney. J Immunol 128: 1659-1663, 1982
36. Camussi G, Tetta C, Mazzucco G, Vercellone A: The brush border of proximal tubules of normal human kidney activates the alternative pathway of the complement system in vitro. Ann N Y Acad Sci 420: 321-324, 1983
37. Ichida S, Yuzawa Y, Okada H, Yoshioka K, Matsuo S: Localization of the complement regulatory proteins in the normal human kidney. Kidney Int 46: 89-96, 1994
38. Hansch GM, Schonermark M, Wagner C, Schieren G, Jahn B: The terminal complement complex C5b-9: A possible mediator of acute and chronic glomerulonephritis. In: Proceedings of the XIth International Congress of Nephrology, Vol. 2, edited by Hatano M, New York, Springer-Verlag, 1991, pp 888-897
39. Torbohm I, Schonermark M, Wingen AM, Berger B, Rother K, Hansch GM: C5b-8 and C5b-9 modulate the collagen release of human glomerular epithelial cells. Kidney Int 37: 1098-1104, 1990
40. Clark EC, Nath KA, Hostetter MK, Hostetter TH: Role of ammonia in progressive interstitial nephritis. Am J Kidney Dis 17: 15-19, 1991
41. Rustom R, Jackson MJ, Critchley M, Bone JM: Tubular metabolism of aprotinin 99mTc and urinary ammonia: Effects of proteinuria. Miner Electrolyte Metab 18: 108-112, 1992
42. Kuncio GS, Neilson EG, Haverty T: Mechanisms of tubulointerstitial fibrosis. Kidney Int 39: 550-556, 1991
43. Oken DE, Kirschbaum BB, Landwehr DM: Micropuncture studies of the mechanisms of normal and pathologic albuminuria. Contrib Nephrol 24: 1-7, 1981
44. Burton C, Harris KP: The role of proteinuria in the progression of chronic renal failure. Am J Kidney Dis 27: 765-775, 1996
45. Thomas ME, Schreiner GF: Contribution of proteinuria to progressive renal injury: Consequences of tubular uptake of fatty acid bearing albumin. Am J Nephrol 13: 385-398, 1993
46. Wolf G, Neilson EG: Molecular mechanisms of tubulointerstitial hypertrophy and hyperplasia. Kidney Int 39: 401-420, 1991
47. Wang Y, Chen J, Chen L, Tay YC, Rangan GK, Harris DC: Induction of monocyte chemoattractant protein-1 in proximal tubule cells by urinary protein. J Am Soc Nephrol 8: 1537-1545, 1997
48. Zoja C, Morigi M, Figliuzzi M, Bruzzi I, Oldroyd S, Benigni A, Ronco P, Remuzzi G: Proximal tubular cell synthesis and secretion of endothelin-1 on challenge with albumin and other proteins. Am J Kidney Dis 26: 934-941, 1995
49. Zoja C, Donadelli R, Colleoni S, Figliuzzi M, Bonazzola S, Morigi M, Remuzzi G: Protein overload stimulates RANTES production by proximal tubular cells depending on NF-κB activation. Kidney Int 53: 1608-1615, 1998
50. Zager RA, Schimpf BA, Bredl CR, Gmur DJ: Inorganic iron effects on in vitro hypoxic proximal renal tubular cell injury. J Clin Invest 91: 702-708, 1993