The β1 cytoplasmic domain regulates the laminin-binding specificity of the α7X1 integrin

Molecular Biology of the Cell

Volumn 14, Issue 9, 2003, Pages 3507-3518

  Yeh, Ming Guang ^a   Ziober, Barry L ^a,c   Liu, Baomei ^a   Lipkina, Galina ^a   Vizirianakis, Ioannis S ^a,d   Kramer, Randall H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA7 INTEGRIN; COMPLEMENTARY DNA; INTEGRIN; LAMININ; LAMININ 1; LAMININ 4; MEROSIN; UNCLASSIFIED DRUG; ALPHA INTEGRIN; BETA1 INTEGRIN; CARRIER PROTEIN; ISOPROTEIN; LEUKOCYTE ANTIGEN; PROTEIN SUBUNIT;

ALTERNATIVE RNA SPLICING; ANIMAL TISSUE; ARTICLE; BETA SHEET; BINDING AFFINITY; CELL ADHESION; CELL DIFFERENTIATION; CELL MOTILITY; CELL SURVIVAL; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIGAND BINDING; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; ANIMAL; CELL CULTURE; FLOW CYTOMETRY; GENETICS; METABOLISM; MOLECULAR CLONING; PHYSIOLOGY;

ANIMALIA;

ALTERNATIVE SPLICING; ANIMALS; ANTIGENS, CD; ANTIGENS, CD29; CARRIER PROTEINS; CELL ADHESION; CLONING, MOLECULAR; FLOW CYTOMETRY; HUMANS; INTEGRIN ALPHA CHAINS; LAMININ; MICE; PROTEIN ISOFORMS; PROTEIN SUBUNITS; TUMOR CELLS, CULTURED;

EID: 0141744814     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-12-0824     Document Type: Article

References (51)

1. Bao, Z.Z., Lakonishok, M., Kaufman, S., and Horwitz, A.F. (1993). Alpha7beta1 integrin is a component of the myotendinous junction on skeletal muscle. J. Cell Sci. 106, 579-589.
2. Belkin, A.M., Retta, S.F., Pletjushkina, O.Y., Balzac, F., Silengo, L., Fassler, R., Koteliansky, V.E., Burridge, K., and Tarone, G. (1997). Muscle beta1D integrin reinforces the cytoskeleton-matrix link: modulation of integrin adhesive function by alternative splicing. J. Cell Biol. 139, 1583-1595.
3. Belkin, A.M., Zhidkova, N.I., Balzac, F., Altruda, F., Tomatis, D., Maier, A., Tarone, G., Koteliansky, V.E., and Burridge, K. (1996). Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in non-muscle cells. J. Cell Biol. 132, 211-226.
4. Brancaccio, M., Cabodi, S., Belkin, A.M., Collo, G., Koteliansky, V.E., Tomatis, D., Altruda, F., Silengo, L., and Tarone, G. (1998). Differential onset of expression of alpha7 and beta1D integrins during mouse heart and skeletal muscle development [In Process Citation]. Cell Adhes. Commun. 5, 193-205.
5. Colognato, H., and Yurchenco, P.D. (2000). Form and function: the laminin family of heterotrimers. Dev. Dyn. 218, 213-234.
6. Crawley, S., Farrell, E.M., Wang, W., Gu, M., Huang, H.Y., Huynh, V., Hodges, B.L., Cooper, D.N., and Kaufman, S.J. (1997). The alpha7beta1 integrin mediates adhesion and migration of skeletal myoblasts on laminin. Exp. Cell Res. 235, 274-286.
7. Delwel, G.O., de Melker, A.A., Hogervorst, F., Jaspars, L.H., Fles, D.L., Kuikman, I., Lindblom, A., Paulsson, M., Timpl, R., and Sonnenberg, A. (1994). Distinct and overlapping ligand specificities of the alpha3Abeta1 and alpha6Abeta 1 integrins: recognition of laminin isoforms. Mol. Biol. Cell 5, 203-215.
8. Diamond, M.S., and Springer, T.A. (1994). The dynamic regulation of integrin adhesiveness. Curr. Biol. 4, 506-517.
9. Faull, R.J., Kovach, N.L., Harian, J.M., and Ginsberg, M.H. (1994). Stimulation of integrin-mediated adhesion of T lymphocytes and monocytes: two mechanisms with divergent biological consequences. J. Exp. Med. 179, 1307-1316.
10. Gimond, C., Baudoin, and Sonnenberg, A. (2000). Defects in adhesion and migration, but not in proliferation and differentiation, of embryonic stem cells upon replacement of integrin subunit beta1A by beta1D. Differentiation 66, 93-105.
11. Gullberg, D., Tiger, C.F., and Velling, T. (1999). Laminins during muscle development and in muscular dystrophies. Cell Mol. Life Sci. 56, 442-460.
12. Hayashi, Y.K., et al. (1998). Mutations in the integrin alpha7 gene cause congenital myopathy. Nat. Genet. 19, 94-97.
13. Hodges, B.L., Hayashi, Y.K., Nonaka, I., Wang, W., Arahata, K., and Kaufman, S.J. (1997). Altered expression of the alpha7beta1 integrin in human and murine muscular dystrophies. J. Cell Sci. 110, 2873-2881.
14. Hughes, P.E., and Pfaff, M. (1998). Integrin affinity modulation. Trends Cell. Biol. 8, 359-364.
15. Hughes, P.E., Renshaw, M.W., Pfaff, M., Forsyth, J., Keivens, V.M., Schwartz, M.A., and Ginsberg, M.H. (1997). Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway. Cell 88, 521-530.
16. Humphries, M.J. (1996). Integrin activation: the link between ligand binding and signal transduction. Curr. Opin. Cell Biol. 8, 632-640.
17. Jones, J.I., Doerr, M.E., and Clemmons, D.R. (1995). Cell migration: interactions among integrins, IGFs and IGFBPs. Prog. Growth Factor Res. 6, 319-327.
18. Kaariainen, M., Nissinen, L., Kaufman, S., Sonnenberg, A., M., J., Heino, J., and Kalimo, H. (2002). Expression of alpha7Beta1 integrin splicing variants during skeletal muscle regeneration. Am. J. Pathol. 161, 1023-1031.
19. Kaariainen, M., Liljamoa, T., Pelto-Huikko, M., Heino, J., and Kalimo, H. (2001). Regulation of a7 integrin by mechanical stress during skeletal muscle regeneration. Neuromuscul. Disord. 11, 360-369.
20. Kaufman, S.J., George-Weinstein, M., and Foster, R.F. (1991). In vitro development of precursor cells in the myogenic lineage. Dev. Biol. 146, 228-238.
21. Kaufman, S.J., Parks, C.M., Bohn, J., and Faiman, L.F. (1980). Transformation is an alternative to normal skeletal muscle development. Exp. Cell. Res. 125, 333-349.
22. Liddington, R.C., and Ginsberg, M.H. (2002). Integrin activation takes shape. J. Cell Biol. 158, 833-839.
23. Longhurst, C.M., and Jennings, L.K. (1998). Integrin-mediated signal transduction. Cell Mol. Life Sci. 54, 514-526.
24. Maemura, M., Akiyama, S.K., Woods, V.L., Jr., and Dickson, R.B. (1995). Expression and ligand binding of alpha 2 beta 1 integrin on breast carcinoma cells. Clin. Exp. Metastasis 13, 223-235.
25. Martin, P.T., Kaufman, S.J., Kramer, R.H., and Sanes, J.R. (1996). Synaptic integrins in developing, adult, and mutant muscle: selective association of alpha1, alpha7A, and alpha7B integrins with the neuromuscular junction. Dev. Biol. 174, 125-139.
26. Mayer, U., Saher, G., Fassler, R., Bornemann, A., Echtermeyer, F., von der Mark, H., Miosge, N., Poschl, E., and von der Mark, K. (1997). Absence of integrin alpha 7 causes a novel form of muscular dystrophy. Nat. Genet. 17, 318-323.
27. Mould, A.P. (1996). Getting integrins into shape: recent insights into how integrin activity is regulated by conformational changes. J. Cell Sci. 109, 2613-2618.
28. Pedrosa-Domellof, F., Tiger, C.F., Virtanen, I., Thornell, L.E., and Gullberg, D. (2000). Laminin chains in developing and adult human myotendinous junctions. J. Histochem. Cytochem. 48, 201-210.
29. Pegoraro, E., et al. (2002). Integrin alpha 7 beta 1 in muscular dystrophy/myopathy of unknown etiology. Am. J. Pathol. 160, 2135-2143.
30. Pfaff, M., Liu, S., Erle, D.J., and Ginsberg, M.H. (1998). Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins. J. Biol. Chem. 273, 6104-6109.
31. Schwartz, M.A., Schaller, M.D., and Ginsberg, M.H. (1995). Integrins: emerging paradigms of signal transduction. Annu. Rev. Cell Dev. Biol. 11, 549-599.
32. Shimaoka, M., Takagi, J., Springer, T.A. (2002). Conformational regulation of integrin structure and function. Annu. Rev. Biophys. Biomol. Struct. 31, 485-516.
33. Song, W.K., Wang, W., Sato, H., Bielser, D.A., and Kaufman, S.J. (1993). Expression of alpha 7 integrin cytoplasmic domains during skeletal muscle development: alternate forms, conformational change, and homologies with serine/threonine kinases and tyrosine phosphatases. J. Cell Sci. 106, 1139-1152.
34. Spinardi, L., Einheber, S., Cullen, T., Milner, T.A., and Giancotti, F.G. (1995). A recombinant tail-less integrin beta 4 subunit disrupts hemidesmosomes, but does not suppress alpha 6 beta 4-mediated cell adhesion to laminins. J. Cell Biol. 129, 473-487.
35. Springer, T.A. (1997). Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain. Proc. Natl. Acad. Sci. USA 94, 65-72.
36. Takagi, J., Petre, B.M., Walz, T., Springer, T.A. (2002). Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell 110, 599-611.
37. Vachon, P.H., Xu, H., Liu, L., Loechel, F., Hayashi, Y., Arahata, K., Reed, J.C., Wewer, U.M., and Engvall, E. (1997). Integrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophy. J. Clin. Invest. 100, 1870-1881.
38. van der Flier, A., Gaspar, A.C., Thorsteinsdottir, S., Baudoin, C., Groeneveld, E., Mummery, C.L., and Sonnenberg, A. (1997). Spatial and temporal expression of the beta1D integrin during mouse development. Dev. Dyn. 210, 472-486.
39. van der Flier, A., Kuikman, I., Baudoin, C., van der Neut, R., and Sonnenberg, A. (1995). A novel beta1 integrin isoform produced by alternative splicing: unique expression in cardiac and skeletal muscle. FEBS Lett. 369, 340-344.
40. Vizirianakis, I.S., Yao, C.C., Chen, Y., Ziober, B.L., Tsiftsoglou, A.S., and Kramer, R.H. (2001). Transfection of MCF-7 carcinoma cells with human integrin alpha7 cDNA promotes adhesion to laminin. Arch. Biochem. Biophys. 385, 108-116.
41. von der Mark, H., Williams, I., Wendler, O., Sorokin, L., von der Mark, K., and Poschl, E. (2002). Alternative splice variants of alpha7beta1 integrin selectively recognize different laminin isoforms. J. Biol. Chem. 277, 6012-6016.
42. Wong, N.C., Mueller, B.M., Barbas, C.F., Ruminski, P., Quaranta, V., Lin, E.C., and Smith, J.W. (1998). Alphav integrins mediate adhesion and migration of breast carcinoma cell lines. Clin. Exp. Metastasis 16, 50-61.
43. Xiong, J.P., Stehle, T., Zhang, R., Joachimiak, A., Frech, M., Goodman, S.L., and Arnaout, M.A. (2002). Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science 296, 151-155.
44. Yao, C.C., Breuss, J., Pytela, R., and Kramer, R.H. (1997). Functional expression of the alpha 7 integrin receptor in differentiated smooth muscle cells. J. Cell Sci. 110, 1477-1487.
45. Yao, C.C., Ziober, B.L., Squillace, R.M., and Kramer, R.H. (1996a). Alpha7 integrin mediates cell adhesion and migration on specific laminin isoforms. J. Biol. Chem. 271, 25598-25603.
46. Yao, C.C., Ziober, B.L., Sutherland, A.E., Mendrick, D.L., and Kramer, R.H. (1996b). Laminins promote the locomotion of skeletal myoblasts via the alpha7 integrin receptor. J. Cell Sci. 109, 3139-3150.
47. Zent, R., Fenczik, C.A., Calderwood, D.A., Liu, S., Dellos, M., and Ginsberg, M.H. (2000). Class- and splice variant-specific association of CD98 with integrin beta cytoplasmic domains. J. Biol. Chem. 275, 5059-5064.
48. Zhang, Z., Vuori, K., Wang, H., Reed, J.C., and Ruoslahti, E. (1996). Integrin activation by R-ras. Cell 85, 61-69.
49. Zhidkova, N.I., Belkin, A.M., and Mayne, R. (1995). Novel isoform of beta I integrin expressed in skeletal and cardiac muscle. Biochem. Biophys. Res. Commun. 214, 279-285.
50. Ziober, B.L., Chen, Y.Q., and Kramer, R.H. (1997). The laminin-binding activity of the alpha7 integrin receptor is defined by developmentally regulated splicing in the extracellular domain. Mol. Biol. Cell 8, 1723-1734.
51. Ziober, B.L., Vu, M.P., Waleh, N., Crawford, J., Lin, C.S., and Kramer, R.H. (1993). Alternative extracellular and cytoplasmic domains of the integrin alpha 7 subunit are differentially expressed during development. J. Biol. Chem. 268, 26773-26783.