The laminin-binding activity of the α7 integrin receptor is defined by developmentally regulated splicing in the extracellular domain

Molecular Biology of the Cell

Volumn 8, Issue 9, 1997, Pages 1723-1734

  Ziober, Barry L ^a   Chen, Yaoqi ^a   Kramer, Randall H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN; LAMININ;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIGAND BINDING; MUSCLE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0030840417     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.8.9.1723     Document Type: Article

References (57)

1. Arroyo, A.G., Sanchez-Madrid, P., Campamero, M.R., Martin-Padura, I., Dejana, E., and Sanchez-Madrid, F. (1992). Regulation of the VLA integrin-ligand interactions through the β1 subunit. J. Cell Biol. 117, 659-670.
2. Bazzoni, G., Shih, D.I., Buck, C.A., and Hemler, M.E. (1995). Monoclonal antibody 9EG7 defines a novel β1 integrin epitope induced by soluble ligand and manganese, but inhibited by calcium. J. Biol. Chem. 270, 25570-25577.
3. Belkin, A.M., Zhidkova, N.I., Balzac, F., Altruda, F., Tomatis, D., Maier, A., Tarone, G., Koteliansky, V.E., and Burridge, K. (1996). Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in non-muscle cells. J. Cell Biol. 132, 211-226.
4. Brown, N.H., King, D.L., Wilcox, M., and Kafatos, F.C. (1989). Developmentally regulated alternative splicing of Drosophila integrin PS2 alpha transcripts. Cell 59, 185-195.
5. Chan, B.M.C., and Hemler, M.E. (1993). Multiple functional forms of the integrin VLA-2 can be derived from a single α2 cDNA clone: interconversion of forms induced by an anti-β1 antibody. J. Cell Biol. 120, 537-543.
6. Collo, G., Star, L., and Quaranta, V. (1993). A new isoform of the laminin receptor integrin α7β1 is developmentally regulated in skeletal muscle. J. Biol. Chem. 268, 19019-19024.
7. Cooper, H.M., Tamura, R.N., and Quaranta, V. (1991). The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin. J. Cell Biol. 115, 843-850.
8. Crawley, S.C., Kaufman, S.J., and Cooper, D.N.W. (1996). Comparison of rat myoblast receptors for laminin-1 and laminin-2-4. Mol. Biol. Cell 7(suppl), 67a. (Abstract).
9. Delwel, G.O., et al. (1994). Distinct and overlapping ligand specificities of the alpha 3A beta 1 and alpha 6A beta 1 integrins: recognition of laminin isoforms. J. Biol. Chem. 268, 25865-25875.
10. Delwel, G.O., Hogervorst, F., Kuikman, I., Paulsson, M., Timpl, R., and Sonnenberg, A. (1993). Expression and function of the cytoplasmic variants of the integrin alpha 6 subunit in transfected K562 cells. Activation-dependent adhesion and interaction with isoforms of laminin. J. Biol. Chem. 268, 25865-25875.
11. Delwel, G.O., Kuikman, I., and Sonnenberg, A. (1995). An alternatively spliced exon in the extracellular domain of the human alpha 6 integrin subunit-functional analysis of the alpha 6 integrin variants. Cell Adh. Comm. 3, 143-161.
12. Diamond, M.S., and Springer, T.A. (1994). The dynamic regulation of integrin adhesiveness. Curr. Biol. 4, 506-517.
13. Djaffar, I., Chen, Y.P., Creminon, C., Maclouf, J., Cieutat, A.M., Gayet, O., and Rosa, J.P. (1994). A new alternative transcript encodes a 60 kDa truncated form of integrin beta 3. Biochem. J. 300, 69-74.
14. Faull, R.J., Kovach, N.L., Harlan, J.M., and Ginsberg, M.H. (1993). Affinity modulation of integrin alpha 5 beta 1: regulation of the functional response by soluble fibronectin. J. Cell Biol. 121, 155-162.
15. Fornaro, M., Zheng, D.Q., and Languino, L.R. (1995). The novel structural motif Gln795-Gln802 in the integrin beta 1C cytoplasmic domain regulates cell proliferation. J. Biol. Chem, 270, 24666-24669.
16. Gehlsen, K.R., Dickerson, K., Argraves, W.S., Engvall, E., and Ruoslahti, E. (1989). Subunit structure of laminin-binding integrin and localization of its binding site on laminin. J. Biol. Chem. 264, 19034-19038.
17. Grinblat, Y., Zusman, S., Yee, G., Hynes, R.O., and Kafatos, F.C. (1994). Functions of the cytoplasmic domain of the beta PS integrin subunit during Drosophila development. Development 120, 91-102.
18. Gu, M., Wang, W., Song, W.K., Cooper, D.N.W., and Kaufman, S.J. (1994). Selective modulation of the interaction of α7β1 integrin with fibronectin and laminin by L-14 lectin during skeletal muscle differentiation. J. Cell. Sci. 107, 175-181.
19. Hemler, M.E., Weitzman, J.B., Pasqualini, R., Kawaguchi, S., Kassner, P.D., and Berdichevsky, F.B. (1994). Structure, biochemical properties, and biological functions of integrin cytoplasmic domains. In: Integrins: The Biological Problems, ed. Y. Takada, Boca Raton, FL: CRC Press, 1-35.
20. Hogervorst, F., Kuikman, I., van Kessel, A.G., and Sonnenberg, A. (1991). Molecular cloning of the human alpha 6 integrin subunit. Alternative splicing of alpha 6 mRNA and chromosomal localization of the alpha 6 and beta 4 genes. Eur. J. Biochem. 199, 425-433.
21. Hughes, P.E., Renshaw, M.W., Pfaff, M., Forsyth, J., Keivens, V.M., Schwartz, M.A., and Ginsberg, M.H. (1997). Suppression of integrin activation: a novel function of a ras/raf-initiated MAP kinase pathway. Cell 88, 521-530.
22. Humphries, M.J. (1996). Integrin activation: the link between ligand binding and signal transduction. Curr. Opin. Cell Biol. 8, 632-640.
23. Hynes, R.O. (1992). Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69, 11-25.
24. Irie, A., Kamata, T., Puzon-McLaughlin, W., and Takada, Y. (1995). Critical amino acid residues for ligand binding are clustered in a predicted β-turn of the third N-terminal repeat in the integrin α4 and α5 subunits. EMBO J. 14, 5550-5556.
25. Kamata, T., Puzon, W., and Takada, Y. (1995). Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, cd49d/CD29). Biochem. J. 305, 945-951.
26. Kawaguchi, S., and Hemler, M.E. (1993). Role of the alpha subunit cytoplasmic domain in regulation of adhesive activity mediated by the integrin VLA-2. J. Biol. Chem. 268, 16279-16285.
27. Kramer, R.H., Vu, M.P., Cheng, Y.F., Ramos, D.M., Timpl, R., and Waleh, N. (1991). The laminin-binding integrin α7β1: functional characterization and expression in normal and malignant melanocytes. Cell. Regul. 2, 805-817.
28. Kramer, R.H. (1994). Isolation and characterization of integrin laminin receptors. Methods Enzymol. 245, 129-147.
29. Languino, L.R., and Ruoslahti, E. (1992). An alternative form of the integrin beta 1 subunit with a variant cytoplasmic domain. J. Biol. Chem. 267, 7116-7120.
30. Lin, C.S., Zhang, K., and Kramer, R. (1993). Alpha 6 integrin is up-regulated in step increments accompanying neoplastic transformation and tumorigenic conversion of human fibroblasts. Cancer Res. 53, 2950-2953.
31. Martin, P.T., Kaufman, S.J., Kramer, R.H., and Sanes, J.R. (1996). Synaptic integrins in developing, adult, and mutant muscle: selective association of alphal, alpha7A, and alpha7B integrins with the neuromuscular junction. Dev. Biol. 174, 125-139.
32. Matter, M.L., and Laurie, G.W. (1994). A novel laminin E8 cell adhesion site required for lung alveolar formation in vitro. J. Cell Biol. 124, 1083-1090.
33. Meredith, J., Jr., Takada, Y., Fornaro, M., Languino, L.R., and Schwartz, M.A. (1995). Inhibition of cell cycle progression by the alternatively spliced integrin beta 1C. Science 269, 1570-1572.
34. Mould, P.A. (1996). Getting integrin into shape: recent insights into how integrin activity is regulated by conformational changes. J. Cell Sci. 109, 2613-2618.
35. Picker, L.J., Treer, J.R., Nguyen, M., Terstappen, L.W., Hogg, N., and Yednock, T. (1993). Coordinate expression of beta 1 and beta 2 integrin "activation" epitopes during T cell responses in secondary lymphoid tissue. Eur. J. Immunol. 23, 2751-2757.
36. Puzon-McLaughlin, W., Yednock, T.A., and Takada, Y. (1996). Regulation of conformation and ligand binding function of integrin alpha5betal by the betal cytoplasmic domain. J. Biol. Chem. 271, 16580-16585.
37. Roote, C.E., and Zusman, S. (1996). Alternatively spliced forms of the Drosophila αps1 subunit if integrin are sufficient for viability and can replace the function of the αps1 subunit if integrin in the retina. Development 122, 1985-1994.
38. Sanchez-Mateos, P., Cabanas, C., and Sanchez-Madrid, F. (1996). Regulation of integrin function. Cancer Biol. 7, 99-109.
39. Schwartz, M.A., Schaller, M.D., and Ginsberg, M.H. (1995). Integrins: emerging paradigms of signal transduction. Annu. Rev. Cell Dev. Biol. 11, 549-599.
40. Shimizu, Y., Van Seventer, G.A., Horgan, K.J., and Shaw, S. (1990). Regulated expression and function of three VLA (beta 1) integrin receptors on T cells. Nature 345, 250-253.
41. Song, W.K., Wang, W., Sato, H., Bielser, D.A., and Kaufman S.J. (1993). Expression of alpha 7 integrin cytoplasmic domains during skeletal muscle development: alternate forms, conformational change, and homologies with serine/threonine kinases and tyrosine phosphatases, J. Cell Sci. 106, 1139-1152.
42. Song, W.K., Wang, W., Foster, R.F., Bielser, D.A., and Kaufman, S.J. (1992). H36-α7 is a novel integrin alpha chain that is developmentally regulated during skeletal myogenesis. J. Cell. Biol. 117, 643-657.
43. Suzuki, S., and Naitoh, Y. (1990). Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells. EMBO J. 9, 757-763.
44. Takada, Y., and Puzon, W. (1993). Identification of a regulatory region of integrin β1 subunit using activating and inhibiting antibodies. J. Biol. Chem. 263, 17597-17601.
45. Tamura, R.N., Cooper, H.M., Collo, G., and Quaranta, V. (1991). Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains. Proc. Natl. Acad. Sci. USA 88, 10183-10187.
46. Tennenbaum, T., Belanger, A.J., Click, A.B., Tamura, R., Quaranta, V., Yuspa, S.H. (1995). A splice variant of alpha 6 integrin is associated with malignant conversion in mouse skin tumorigenesis. Proc. Natl. Acad. Sci. USA 92, 7041-7045.
47. Tuckwell, D.S., Humphries, M.J., and Brass, A. (1994). A secondary structure model of the integrin alpha subunit N-terminal domain based on analysis of multiple alignments. Cell Adh. Comm. 2, 385-402.
48. van der Flier, A., Kuikman, I., Baudoin, C., van der Neut, R., and Sonnenberg, A. (1995) A novel beta 1 integrin isoform produced by alternative splicing: unique expression in cardiac and skeletal muscle. FEBS Lett. 369, 340-344.
49. van Kuppeveit, T.H., Languino, L.R., Gailit, J.O., Suzuki, S., and Ruoslahti, E. (1989) An alternative cytoplasmic domain of the integrin beta 3 subunit. Proc. Natl. Acad. Sci. USA 86, 5415-5418.
50. Wang, W., Wu, W., Desai, T., Ward, D.C., and Kaufman, S.J. (1995). Localization of the alpha 7 integrin gene (ITGA7) on human chromosome 12q13: clustering of integrin and Hox genes implies parallel evolution of these gene families. Genomics 26, 568-570.
51. Weitzman, J.B., Pasqualini, R., Takada, Y., and Hemler, M. (1993). The function of distinct regulation of the integrin VLA-3 in cell adhesion, spreading, and homotypic cell aggregation. J. Biol. Chem. 268, 8651-8657.
52. Yao, C.-C., Ziober, B.L., Sutherland, A.E., Mendricks, D.L., and Kramer, R.H. (1996a). Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor. J. Cell Sci. 109, 3139-3150.
53. Yao, C.-C., Ziober, B.L., Squillace, R.M., and Kramer, R.H. (1996b). Alpha? integrin mediates cell adhesion and migration on specific laminin isoforms. J. Biol. Chem. 271, 25598-25603.
54. Yao, C.-C., Breuss, J., Pytela, R., and Kramer, R.H. (1997). Functional expression of the alpha 7 integrin receptor in differentiated smooth muscle cells. J. Cell Sci. 110, 1477-1487.
55. Zavortink, M., Bunch, T.A., and Brower, D.L. (1993). Functional properties of alternatively spliced forms of the Drosophila PS2 integrin alpha subunit. Cell Adh. Comm. 1, 251-264.
56. Zhidkova, N.I., Belkin, A.M., and Mayne, R. (1995). Novel isoform of beta 1 integrin expressed in skeletal and cardiac muscle. Biochem. Biophys. Res. Commun. 214, 279-285.
57. Ziober, B.L., Vu, M.P., Waleh, N., Crawford, J., Lin, C.-S., and Kramer, R.H. (1993). Alternative extracellular and cytoplasmic domains of the integrin α7 subunit are differentially expressed during development. J. Biol. Chem. 268, 26773-26783.