Affordable proteomics: The two-hybrid systems

Current Opinion in Molecular Therapeutics

Volumn 5, Issue 3, 2003, Pages 266-270

  Gillespie, Marc ^a  

^a ST JOHN'S UNIVERSITY   (United States)

Author keywords

Biomarker; Cancer biology; cDNA; Drug development; Genetic libraries; Proteomics; Toxicology; Two hybrid

Indexed keywords

BIOLOGICAL MARKER;

AMINO ACID SEQUENCE; ARTICLE; CANCER RESEARCH; CLINICAL RESEARCH; FEASIBILITY STUDY; GEL ELECTROPHORESIS; GENE LIBRARY; INTERMETHOD COMPARISON; METHODOLOGY; MOLECULAR BIOLOGY; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; PROTEOMICS; RATING SCALE; SCREENING TEST; SEPARATION TECHNIQUE; TWO HYBRID SYSTEM;

GENE LIBRARY; HUMANS; PROTEINS; PROTEOMICS; REAGENT KITS, DIAGNOSTIC; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 0141725451     PISSN: 14648431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Boguski MS: Biosequence exegesis. Science (1999) 286(5439):453-455.
2. Page MJ, Amess B, Rohlff C, Stubberfield C, Parekh R: Proteomics: A major new technology for the drug discovery process. Drug Disc Today (1999) 4(2):55-62.
3. Anderson NL, Matheson AD, Steiner S: Proteomics: Applications in basic and applied biology. Curr Opin Biotechnol (2000) 11(4):408-412.
4. Haynes PA, Yates JR 3rd: Proteome profiling-pitfalls and progress. Yeast (2000) 17(2):81-87.
5. Jain KK: Proteomics: New technologies and their applications. Drug Disc Today (2001) 6(9):457-459.
6. Pandey A, Mann M: Proteomics to study genes and genomes. Nature (2000) 405(6788):837-846.
7. Rabilloud T: Two-dimensional gel electrophoresis in proteomics: Old, old fashioned, but it still climbs up the mountains. Proteomics (2002) 2(1):3-10.
8. Herbert BR, Harry JL, Packer NH, Gooley AA, Pedersen SK, Williams KL: What place for polyacrylamide in proteomics? Trends Biotechnol (2001) 19(10 Suppl):3-9.
9. Fields S, Song O: A novel genetic system to detect protein-protein interactions. Nature (1989) 340(6230):245-246.
10. Chien CT, Bartel PL, Sternglanz R, Fields S: The two-hybrid system: A method to identify and clone genes for proteins that interact with a protein of interest. Proc Natl Acad Sci US4 (1991) 88(21):9578-9582.
11. James P, Halladay J, Craig EA: Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics (1996) 144(4):1425-1436.
12. Vidal M, Brachmann RK, Fattaey A, Harlow E, Boeke JD: Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions. Proc Natl Acad Sci USA (1996) 93(19):10315-10320.
13. Vidal M, Legrain P: Yeast forward and reverse 'n'-hybrid systems. Nucleic Acids Res (1999) 27(4):919-929.
14. Vidal M, Endoh H: Prospects for drug screening using the reverse two-hybrid system. Trends Biotechnol (1999) 17(9):374-381.
15. Vidal M: n-Hybrid systems. Trends Cell Biol (2002) 12(1):56.
16. Serebriiskii IG, Mitina O, Pugacheva EN, Benevolenskaya E, Kotova E, Toby GG, Khazak V, Kaelin WG, Chernoff J, Golemis EA: Detection of peptides, proteins, and drugs that selectively interact with protein targets. Genome Res (2002) 12(11):1785-1791.
17. Ito T, Chiba T, Yoshida M: Exploring the protein interactome using comprehensive two-hybrid projects. Trends Biotechnol (2001) 19(10 Suppl):23-27.
18. Ito T, Ota K, Kubota H, Yamaguchi Y, Chiba T, Sakuraba K, Yoshida M: Roles for the two-hybrid system in exploration of the yeast protein interactome. Mol Cell Proteomics (2002) 1(8):561-566.
19. Ito T, Tashiro K, Muta S, Ozawa R, Chiba T, Nishizawa M, Yamamoto K, Kuhara S, Sakaki Y: Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast proteins. Proc Natl Acad Sci USA (2000) 97(3):1143-1147.
20. Uetz P, Hughes RE: Systematic and large-scale two-hybrid screens. Curr Opin Microbiol (2000) 3(3):303-308.
21. Rain JC, Selig L, De Reuse H, Battaglia V, Reverdy C, Simon S, Lenzen G, Petel F, Wojcik J, Schachter V, Chemama Y at al: The protein-protein interaction map of Helicobacter pylori. Nature (2001) 409(6817):211-215.
22. Kersten B, Burkle L, Kuhn EJ, Giavalisco P, Konthur Z, Lueking A, Walter G, Eickhoff H, Schneider U: Large-scale plant proteomics. Plant Mol Biol (2002) 48(1-2):133-141.
23. McCraith S, Holtzman T, Moss B, Fields S: Genome-wide analysis of vaccinia virus protein-protein interactions. Proc Natl Acad Sci USA (2000) 97(9):4879-4884.
24. Walhout AJ, Sordella R, Lu X, Hartley JL, Temple GF, Brasch MA, Thierry-Mieg N, Vidal M: Protein interaction mapping in C. elegans using proteins involved in vulval development. Science (2000) 287(5450):116-122.
25. Jeong H, Mason SP, Barabasi AL, Oltvai ZN: Lethality and centrality in protein networks. Nature (2001) 411(6833):41-42.
26. Vogelstein B, Lane D, Levine AJ: Surfing the p53 network. Nature (2000) 408(6810):307-310.
27. Schwartz H, Alvares CP, White MB, Fields S: Mutation detection by a two-hybrid assay. Hum Mol Genet (1998) 7(6):1029-1032.
28. Shen Z, Pardington-Purtymun PE, Comeaux JC, Moyzis RK, Chen DJ: Associations of UBE2I with RAD52, UBL1, p53, and RAD51 proteins in a yeast two-hybrid system. Genomics (1996) 37(2):183-186.
29. Iwabuchi K, Li B, Bartel P, Fields S: Use of the two-hybrid system to identify the domain of p53 involved in oligomerization. Oncogene (1993) 8(6):1693-1696.
30. Li B, Fields S: Identification of mutations in p53 that affect its binding to SV40 large T antigen by using the yeast two-hybrid system. FASEB J (1993) 7(10):957-963.
31. Kim YJ, Noguchi S, Hayashi YK, Tsukahara T, Shimizu T, Arahata K: The product of an oculopharyngeal muscular dystrophy gene, poly(A)-binding protein 2, interacts with SKIP and stimulates muscle-specific gene expression. Hum Mol Genet (2001) 10(11):1129-1139.
32. Carvalho F, Gillespie ME: Bringing Proteomics Into the Lab -Proteomics Lab 101. Biochemistry Mol Biol Educ (2003) 31:46-51.
33. Steiner S, Anderson NL: Pharmaceutical proteomics. Ann NY Acad Sci (2000) 919:48-51.
34. BioSupplyNet: http://www.biosupplynet.com.