Biallelic expression of the H19 gene during spontaneous hepatocarcinogenesis in the albumin SV40 T antigen transgenic rat

Molecular Carcinogenesis

Volumn 38, Issue 1, 2003, Pages 40-47

  Manoharan, Herbert ^a   Babcock, Karlee ^a   Willi, Jonathan ^a   Pitot, Henry C ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Expression of imprinted genes; Hepatocarcinogenesis; Loss of imprinting; Transgenic rat

Indexed keywords

ALBUMIN; GENE PRODUCT; RNA; VIRUS ANTIGEN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMOSOME 1Q; CHROMOSOME DUPLICATION; FETUS; FETUS LIVER; GENE EXPRESSION; GENOME IMPRINTING; H19 GENE; LIVER CARCINOGENESIS; LIVER CARCINOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RAT; RAT STRAIN; SIMIAN VIRUS 40; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSGENIC ANIMAL;

ALBUMINS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CARCINOMA, HEPATOCELLULAR; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; INSULIN-LIKE GROWTH FACTOR II; LIVER NEOPLASMS, EXPERIMENTAL; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; RNA, UNTRANSLATED; SEQUENCE ANALYSIS, DNA;

ANIMALIA; SIMIAE; SIMIAN VIRUS 40;

EID: 0141679202     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.10144     Document Type: Article

References (40)

1. Sargent LM, Dragan YP, Sattler G, Xu Y-H, Wiley J, Pitot HC. Specific chromosomal changes in albumin Simian virus 40 T antigen transgenic rat liver neoplasms. Cancer Res 1997;57:3451-3456.
2. Reik W, Walter J. Genomic imprinting: Parental influence on the genome. Nat Rev Genet 2001;2:21-32.
3. Jones PL, Wolffe AP. Relationships between chromatin organization and DNA methylation in determining gene expression. Cancer Biol 1999;9:339-346.
4. Tycko B, Trasler J, Bestor T. Genomic imprinting: Gametic mechanisms and somatic consequences. J Androl 1997;18:480-486.
5. Bartolomei MS, Tilghman SM. Genomic imprinting in mammals. Annu Rev Genet 1997;31:493-525.
6. DeSouza AT, Yamada T, Mills JT, Jirtle RL. Imprinted genes in liver carcinogenesis. FASEB J 1997;11:60-67.
7. Caspary T, Cleary MA, Baker CC, Guan X-J, Tilghman SM. Multiple mechanisms regulate imprinting of the mouse distal chromosome 7 gene cluster. Mol Cell Biol 1998;18:3466-3474.
8. Overall M, Bakker M, Spencer J, Parker N, Smith P, Dziadek M. Genomic imprinting in the rat: Linkage of Igf2 and H19 genes and opposite parental allele-specific expression during embryogenesis. Genomics 1997;45:416-420.
9. Andoh Y, Kuramoto T, Yokoi N, Maihara T, Kitada K, Serikawa T. Correlation between genetic and cytogenetic maps of the rat. Mamm Genome 1998;9:287-293.
10. Bartolomei MS, Zemel S, Tilghman SM. Parental imprinting of the mouse H19 gene. Nature 1991;351:153-155.
11. Zhang Y, Tycko B. Monoallelic expression of the human H19 gene. Nat Genet 1992;1:40-43.
12. Bell AC, Felsenfeld G. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature 2000;405:482-485.
13. Hark AT, Schoenherr CJ, Katz DJ, Ingram RS, Levrose JM, Tilghman SM. CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature 2000;405:486-489.
14. Sasaki H, Ishihara K, Kato R. Mechanisms of Igf2/H19 imprinting: DNA methylation, chromatin and long-distance gene regulation. J Biochem 2000;127:711-715.
15. O'Dell SD, Day INM. Insulin-like growth factor II (IGF-II). Int J Biochem Cell Biol 1998;30:767-771.
16. Sargent L, Dragan Y, Xu Y-H, Sattler G, Wiley J, Pitot HC. Karyotypic changes in a multistage model of chemical hepatocarcinogenesis in the rat. Cancer Res 1996;56:2985-2991.
17. Sargent L, Dragan YP, Babcock K, Wiley J, Klaunig J, Pitot HC. Cytogenetic analysis of three rat liver epithelial cell lines (WBneo, WBHa-ras, and WBraslla) and correlation of an early chromosomal alteration with insulin-like growth factor II expression. Cancer Res 1996;56:2992-2997.
18. Hully JR, Su Y, Lohse JK, et al. Transgenic hepatocarcinogenesis in the rat. Am J Pathol 1994;145:384-397.
19. Sambrook J, Fritsch E, Maniatis T. Molecular cloning: A laboratory Manual, 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 1989. pp 9.16-9.19.
20. Leibovitch MP, Solhonne B, Guillier M, Verelle P, Leibovitch SA. Direct relationship between the expression of tumor suppressor H19 mRNA and c-mos proto-oncogene during myogenesis. Oncogene 1995;10:251-260.
21. Yun K, Soejima H, Merrie AEH, Mccall JL, Reeve AH. Analysis of IGF2 gene imprinting in breast and colorectal cancer by allele specific-PCR. J Pathol 1999;187:518-522.
22. Feinberg AP. Imprinting of a genomic domain of 11p15 and loss of imprinting in cancer: An introduction. Cancer Res 1999;57:1743S-1746S.
23. Ross JA, Radloff GA, Davies SM. H19 and IGF-2 allele-specific expression in hepatoblastoma. Br J Cancer 2000;82:753-756.
24. Looijenga LHJ, Verkerk AJMH, de Groot N, Hochberg AA, Oosterhuis JW. H19 in normal development and neoplasia. Mol Reprod Dev 1997;46:419-439.
25. Banet G, Bibi O, Matouk I, et al. Characterization of human and mouse H19 regulatory sequences. Mol Reprod Rep 2000;27:157-165.
26. Kanduri C, Holmgren C, Pilartz M, et al. The 5′ flank of mouse H19 in an unusual chromatin conformation unidirectionally blocks enhancer-promoter communication. Curr Biol 2000;10:449-457.
27. Adriaenssens E, Lottin S, Dugimont T, et al. Steroid hormones modulate H19 gene expression in both mammary gland and uterus. Oncogene 1999;18:4460-4473.
28. Cranston MJ, Spinka TL, Elson DA, Bartolomei MS. Elucidation of the minimal sequence required to imprint H19 transgenes. Genomics 2001;73:98-107.
29. Malik K, Brown KW. Epigenetic gene deregulation in cancer. Brit J Cancer 2000;83:1583-1588.
30. Jirtle RL. Genomic imprinting and cancer. Exp Cell Res 1999;248:18-24.
31. Ravenel JD, Broman KW, Perlman EJ, et al. Loss of imprinting of insulin-like growth factor-II (IGF2) gene in distinguishing specific biologic subtypes of Wilms tumor. J Natl Cancer Inst 2001;93:1698-1703.
32. Kim HT, Choi BH, Niikawa N, Lee TS, Chang SI. Frequent loss of imprinting of the H19 and IGF-II genes in ovarian tumors. Am J Med Genet 1998;80:391-395.
33. Paulsen M, Ferguson-Smith AC. DNA methylation in genomic imprinting, development and disease. J Pathol 2001;196:97-110.
34. Hibi K, Nakamura H, Hirai A, et al. Loss of H19 imprinting in esophageal cancer. Cancer Res 1996;56:480-482
35. Reik W, Walter J. Evolution of imprinting mechanisms: The battle of the sexes begins in the zygote. Nat Genet 2001;27:255-256.
36. Latham KE. Stage-specific and cell type-specific aspects of genomic imprinting effects in mammals. Differentiation 1995;59:269-282.
37. Jinno Y, Ikeda Y, Yun K, et al. Establishment of functional imprinting of the H19 gene in human developing placentae. Nat Genet 1995;10:318-324.
38. Steenman MJC, Rainer S, Dobry CJ, Grundy P, Horon IL, Feinberg AP. Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumor. Nat Genet 1994;7:433-439.
39. Ariel I, Perlman EJ, Pizov G, et al. The product of the imprinted H19 gene is an oncofetal RNA. J Clin Pathol Mol Pathol 1997;50:34-44.
40. Ciu H, Onyango P, Brandenberg S, Wu Y, Hsieh C, Feinberg AP. Loss of imprinting in colorectal cancer linked to hypomethylation Cancer Res 2002;62:6442-6446.