Elucidation of the minimal sequence required to imprint H19 transgenes

Genomics

Volumn 73, Issue 1, 2001, Pages 98-107

  Cranston, Melanie J ^a,b   Spinka, Tracy L ^a   Elson, David A ^a,c   Bartolomei, Marisa S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b WELLCOME CRC INSTITUTE   (United Kingdom)

^c UCSF Cancer Center   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT;

ALLELE; ANIMAL CELL; ARTICLE; DNA FLANKING REGION; DNA METHYLATION; DNA REPLICATION; GENE DELETION; GENE LOCUS; GENE SEQUENCE; GENOME IMPRINTING; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURAL GENE; TRANSGENE;

EID: 0035308792     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.2001.6514     Document Type: Article

References (33)

1. Imprinting of Igf2 and H19 from a 130 kb YAC transgene
2. Imprinting transgene methylation and genotype-specific modification
3. Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA
4. Genomic imprinting in mammals
5. Epigenetic mechanisms underlying the imprinting of the mouse H19 gene
6. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
7. A silencer element identified in Drosophila is required for imprinting of H19 reporter transgenes in mice
8. Ectopic expression of the H19 gene in mice causes prenatal lethality
9. Genomic imprinting: Lessons from mouse transgenes
10. Imprinting mechanisms
11. The H19 methylation imprint is erased and reestablished differentially on the parental alleles during male germ cell development
12. A 5′ differentially methylated sequence and the 3′ flanking region are necessary for H19 transgene imprinting
13. A potential imprint control element: Identification of a conserved 42 bp sequence upstream of H19
14. Fine-structure mapping of the three mouse α-fetoprotein gene enhancers
15. CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
16. Chromatin conformation of the H19 epigenetic mark
17. Comparative genomic sequencing identifies novel tissue-specific enhancers and sequence elements for methylation-sensitive factors implicated in Igf2/H19 imprinting
18. A transcriptional insulator at the imprinted H19/Igf2 locus
19. The 5′ flank of mouse H19 in an unusual chromatin conformation unidirectionally blocks enhancer-promoter communication
20. Parental allele-specific chromatin configuration in a boundary/imprinting-control element upstream of the mouse H19 gene
21. Cellular assays for Rev
22. Epigenetic inheritance at the agouti locus in the mouse
23. The structural gene of H19 is required for transgene imprinting
24. Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators
25. Detection of specific sequences among DNA fragments separated by gel electrophoresis
26. Role of a 461 bp G-rich repetitive element in H19 transgene imprinting
27. Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function
28. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
29. A 5′ 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development
30. Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethylpaper and rapid hybridization by using dextran sulfate
31. Location of enhancers is essential for the imprinting of H19 and Igf2 genes
32. Imprinted expression of the Igf2r gene depends on an intronic CpG island
33. Two regulatory domains flank the mouse H19 gene