Cytogenetic analysis of three rat liver epithelial cell lines (WBneo, WBHa-ras, and WBrasIIa) and correlation of an early chromosomal alteration with insulin-like growth factor II expression

Cancer Research

Volumn 56, Issue 13, 1996, Pages 2992-2997

  Sargent, Linda ^a   Dragan, Yvonne P ^a   Babcock, Karlee ^a   Wiley, John ^b   Klaunig, James ^c   Pilot, Henry C ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MITOGENIC AGENT; SOMATOMEDIN B;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CHROMOSOME; CHROMOSOME 1; CHROMOSOME 3; CHROMOSOME ANALYSIS; CHROMOSOME DUPLICATION; CONTROLLED STUDY; GENE; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KARYOTYPE; LIVER; LIVER CARCINOGENESIS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; TRISOMY; TUMOR SUPPRESSOR GENE; Y CHROMOSOME;

ANIMALS; CELLS, CULTURED; CHROMOSOME ABERRATIONS; DISEASE PROGRESSION; EPITHELIUM; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR II; KARYOTYPING; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; RAS PROTEINS; RATS; RATS, INBRED F344; TRANSFECTION;

EID: 0029992793     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Tsao, M-S., Smith, J., Nelson, K, and Grisham, J. A dipioid epithelial cell line from normal adult rat liver with phenotypic properties of oval cells. Exp. Cell Res., 154: 38-52, 1984
2. Tsao, M-S., Grisham, J., Nelson, K., and Smith, J. Phenotypic and karyotypic alterations induced in cultured rat hepatic epithelial cells that express oval cell phenotype by exposure to N-methyl-N-nitro-N-nitrosoguanidine Am J. Pathol., 118: 306-315, 1985.
3. Lee, L. W, Tsao, M. S., Grisham, J. W., and Smith, G. J. Emergence of neoplastic transformants spontaneously or after exposure to N-methyl-N-nitro-N-nitrosoguanidine in populations of rat liver epithelial cells cultured under selective and nonselective conditions. Am. J. Pathol., 135: 63-71, 1989.
4. Lee, L. W, Raymond, V. W, Tsao, M. S., Lee, D C., Earp, H. S., and Grisham, J. W. Clonal cosegregation of tumorigenicity with overexpression of c-myc and transforming growth factor α genes in chemically transformed rat liver epithelial cells. Cancer Res., 51: 5238-5244, 1991.
5. Coleman, W., McCullough, K., Esch, G, Civalier, C., Livanos, E., Weissman, B., Grisham, J., and Smith, G Suppression of the tumorigenic phenotype of a rat liver epithelial cell line by the p11.2-p12 region of human chromosome 11. Mol. Carcinog., 13: 220-232, 1995.
6. De Feijter, A. W., Ray, J S., Weghorst, C. M., Klaunig, J. E., Goodman, J. I., Chang, C. C., Ruch, R. J, and Trosko, J. E. Infection of rat liver epithelial cells with v-Ha-ras: correlation between oncogene expression, gap junctional communication, and tumorigenicity. Mol. Carcinog., 3: 54-67, 1990.
7. Yeh, S-H., Chen, P-J., Lai, M-Y., Wang, C-C., and Chen, D-S. Frequent genetic alterations at the distal region of chromosome 1p in human hepatocellular carcinomas Cancer Res., 54: 4188-4192, 1994.
8. Simon, D., Knowles, B. B., and Weith, A. Abnormalities of chromosome 1 and loss of heterozygosity on 1p in primary hepatomas. Oncogene, 6: 765-770, 1991.
9. Walker, G., Hayward, N., Falvey, S., and Cooksley, W. Loss of somatic heterozygosity in hepatocellular carcinomas. Cancer Res., 51: 4367-4370, 1991.
10. Buetow, K. H., Murray, J. C., Israel, J. L., London, W. T., Smith, M. Kew, M, Blanquet, V., Brechot, C., Redeker, A., and Govindarajah, S. Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma. Genetics, 8: 8852-8856, 1989.
11. Walker, G J., Hayward, N. K., Falvery, S., and Cooksley, W G E. Loss of somatic heterozygosity in hepatocellular carcinoma. Cancer Res., 51: 4367-4370, 1991.
12. Urano, Y., Watanabe, K., Lin, C. C., Hino, O., and Tamaoki, T Interstitial chromosomal deletion within 4q11-q13 in a human hepatoma cell line. Cancer Res., 57: 1460-1464, 1991.
13. Fujimori, M., Tokino, T., Hino, O., Kitagawa, T., Tinamura, T., Okamoto, E., Mitsunobu, M., Ishikawa, T., Nakagama, H., Yagura, M, Matsubara, K., and Nakamura, Y. Allelotype of study of primary hepatocellular carcinoma. Cancer Res., 51: 89-93, 1991.
14. Emi, M., Fujiwara, Y., Nakajima, T., Tsuchiya, E., Tsuda, H., Hirohashi, S., Maeda, Y., Tsuruta, K., Miyaki, M., and Nakamura, Y. Frequent loss of heterozygosity for loci on chromosome 8p in hepatocellular carcinoma, colorectal cancer and lung cancer Cancer Res., 52: 5368-5372, 1992.
15. Takahashi, K., Kudo, J, Ishibashi, H, Hirata, Y., and Niho, Y. Frequent loss of heterozygosity on chromosome 22 in hepatocellular carcinoma. Hepatology, 17: 794-799, 1993.
16. Koufos, A., Hansen, M F, Copeland, N. G., Jenkins, N A., Lampkin, B. C., and Cavenee, W. K. Loss of heterozygosity in three embryonal tumors suggests a common pathogenetic mechanism Nature (Lond), 316: 330-334, 1985
17. Zhang, X, Xu, H-J., Murakami, Y., Sachse, R., Yashimura, K., Hirohashi, S., Hu, S-X, Benedict, W F., and Sekiya, T. Deletions of chromosome 13q, mutations in retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma. Cancer Res, 54: 4177-4182, 1994
18. Tsuda, H., Zhang, W., and Shimasato, Y. Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma Proc. Natl. Acad. Sci. USA, 87: 6791-6794, 1990
19. Fujimoto, Y., Hampton, L L., Wirth, P. J., Wang, N. J., Xie, J. P., and Thorgeirsson, S. S Alterations of rumor suppressor genes and allelic losses in human hepatocellular carcinomas in China. Cancer Res., 54: 281-285, 1994.
20. Hsu, H. C, Peng, S. Y., Lei, P. L., and Sheu, J. C. Allelotype and loss of heterozygosity of p53 in primary and recurrent hepatocellular carcinomas A study of 150 patients. Cancer (Phila.), 73: 42-47, 1994.
21. Kanai, Y., Tsuda, H., Oda, T., Sakamoto, M, and Hirohashi, S. Analysis of the neurofibromatosis 2 gene in human breast and hepatocellular carcinomas. Jpn. J. Clin. Oncol, 25 1-4, 1995.
22. Byrne, J, Simms, L., Little, M., Algar, E, and Smith, P. Three non-overlapping regions of chromosome arm 11p allele loss identified in infantile tumours of the adrenal and liver. Genes Chromosomes & Cancer, 8, 104-111, 1993.
23. Sargent, L. M., Sattler, G L., Roloff, B., Xu, Y-H., Sattler, C A., Meisner, L., and Pitot, H. C. Ploidy and specific karyotypic changes during promotion with phenobarbital, 2,5,2′,5′-tetrachlorobiphenyl, and/or 3,4,3′,4′-tetrachlorobiphenyl. Cancer Res., 52: 955-962, 1992.
24. Wolman, S. R., Phillips, T. F., and Klein, K. M Chromosome patterns in rat hepatomas during N-2-fluorenylacetamide carcinogenesis J Natl Cancer Inst, 46: 1261-1269, 1973.
25. Kovi, E., and Morris, H P Chromosome banding studies of several transplantable hepatomas. Adv Enzyme Regul., 14: 139-162, 1983
26. Levan, G., Szpirer, J., Szpirer, C., Klinga, K., Hanson, C., and Quamrul, I. The gene map of the Norway rat (Rattus norvegicus) and comparative mapping with mouse and man. Genomics, 10: 699-718, 1991.
27. Yamada, H., Kuramato, T, and Senkawa, T. A rat genetic linkage map and comparative maps for mouse or human homologous rat genes Mamm Genome, 5. 83-88, 1994.
28. Widmer, U., Schmid, C., Zapf, J., and Froesch, E. R. Effects of insulin like growth factor II on chick embryo hepatocytes. Acta Endocrinol., 108: 237-244, 1985.
29. Yang, D., and Rogler, C E. Analysis of insulin-like growth factor II (IGFII) expression in neoplastic nodules and hepatocellular carcinomas of woodchucks utilizing in situ hybridization and immunohistochemistry. Carcinogenesis (Lond.), 12: 1893-1901, 1991.
30. Christofori, G., Naik, P., and Hanahan, D. A second signal supplied by insulin-like growth factor II in oncogene induced tumorigenesis. Nature (Lond.), 369: 414-418, 1994.
31. Wiley, J. E, Sargent, L. M., Inhorn, S. L., and Meisner, L. F. Comparison of prometaphase chromosome techniques with emphasis on the role of colcemid. In Vitro (Rockville), 20: 937-941, 1984.
32. Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidnium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162: 156-159, 1987.
33. Soares, M. B., Turken, A., Ishii, D., Leslie, M., Vasso, E., Cotter, S., Zeitlin, S., and Efstratiadis, A. Rat insulin-like growth factor II gene a single gene with two promoters expressing a multitranscript family. J. Mol. Biol., 192: 737-752, 1986.
34. Simmons, D, Arriza, J., and Swanson, L. A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabeled single stranded RNA probes. J. Histotechnol., 12: 169-181, 1981.
35. Schirmacher, A., Held, W. A., Yang, D., Chisari, F V, Rustum, Y, and Rogler, C. E. Reactivation of insulin-like growth factor II during hepatocarcinogenesis in transgenic mice suggests a role in malignant growth. Cancer Res, 52: 2549-2556, 1992.
36. Masuda, R, Yoshida, M. C, Sasaki, M., Okuda, A., Sakai, M., and Muramatsu, M Localization of the gene for glutathione S-transferase P on rat chromosome 1 at band q43 Jpn J. Cancer Res., 77: 1055-1058, 1986.
37. Becker, F. F., Fox, R. A., Klein, K. M., and Wolman, S. R. Chromosome patterns in rat hepatocytes during N-2-fluorenylacetamide carcinogenesis. J. Natl. Cancer Inst., 46. 1261-1269, 1971
38. Stedman, J. S, Lee, L. W., Smith, G J, and Grisham, J. W. DNA contents and chromosomes of clonal lines of transformed rat liver epithelial cells and of cells from the derived tumors. Carcinogenesis (Lond.), 15: 963-969, 1994.
39. Funaki, K., Everett, J., Bermudez, E., and Walker, C. Trisomy of rat chromosome 1 associated with mesothelial cell transformation. Cancer Res., 51: 4059-4066, 1991.
40. Aldaz, C. M., Gollahon, L. S, and Chen, A. Systematic hras amplification in ovary-independent mammary tumors: correlation with progressively anaplastic phenotypes. Cancer Res., 53. 5339-5344, 1993.
41. Endo, S., Nettesheim, P., Oshimura, M., and Walker, C. Nonrandom chromosome alterations that correlate with progression to immortality in rat tracheal epithelial cells transformed with N-methyl-N′-nitrosoguanidine. Cancer Res., 50: 740-747, 1990.
42. Gariboldi, M., Manenti, G, Canzian, F., Falvella, F. S., Pierotti, M A., Porta, G. D., Binelli, G., and Dragani, T. A. Chromosome mapping of murine susceptibility loci to liver carcinogenesis. Cancer Res., 53: 209-211, 1993.
43. Byrne, J, Simms, L., Little, M., Algar, E., and Smith, P. Three non-overlapping regions of chromosome arm 11p allele loss identified in infantile tumours of the adrenal and liver. Genes Chromosomes & Cancer, 8: 104-111, 1993.
44. Ichikawa, T., Kyprianou, N., and Isaacs, J. T. Genetic instability and the acquisition of metastatic ability by rat mammary cancer cells following v-H-ras oncogene transfection. Cancer Res., 50. 6349-6357, 1990.
45. Aldaz, M C., Chen, A., Gollahon, L. S., Russo, J., and Zappler, K. Nonrandom abnormalities involving chromosome 1 and Harvey-ras-1 alleles in rat mammary tumor progression. Cancer Res., 52: 4791-4798, 1992.
46. Levan, G, and Levan, A. Specific chromosome changes in malignancy: studies in rat sarcomas induced by two polycyclic hydrocarbons. Hereditas, 79: 161-198, 1975.
47. Sills, R C., Goldsworthy, T. L., and Sleight, S. D Tumor-promoting effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and phenobarbital in initiated weanling Sprague-Dawley rats: a quantitative phenotypic and ras p21 protein study. Toxicol. Pathol., 22: 270-281, 1994.
48. Ichikawa, F., Takaku, F., Nagao, M., Ochiai, M., Hayashi, K., Takayama, S., and Sugimura, T. Activated oncogenes in a rat hepatocellular carcinoma induced by 2-amino-3-methyl-imidiazo(4, 5f)quinoline. Gann, 76: 425-428, 1985
49. Rogler, C. E., Yang, D., Rossetti, L, and Donohoe, J. Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice. J. Biol. Chem, 269: 13779-13784, 1994.
50. Carrani, E., Lasserre, C., Kemeny, F., Franco, D., and Brechet, C. Expression of insulin growth factor II, alpha-fetoprotein and hepatitis B virus transcripts in human primary liver cancer. Hepatology, 13: 644-649, 1991.
51. Daughaday, W H., Wu, J C., Lee, S. D., and Kapadia, M. Abnormal processing of pro-IGF-II in patients with hepatoma and in some hepatitis B virus antibody-positive asymptomatic individuals. J. Lab. Clin. Med., 116. 555-562, 1990.
52. Lomas, E., LeBail, B, Housset, C, Boucher, O., and Brechot, C Localization of insulin-like growth factor II and hepatitis B virus mRNAs and proteins in human hepatocellular carcinomas Lab Invest., 64: 98-104, 1991
53. DeLeon, D. D., Terry, C., Asmerom, Y, and Nissley, P. Insulin-like growth factor II modulates the routing of cathepsin D in MCF-7 breast cancer cells. Endocrinology, 137: 1-10, 1996.
54. Hayashi, K. Chromosome patterns in rat hepatocytes during N-2-fluoranyl acetamide carcinogenesis J. Natl. Cancer Inst., 46: 1261-1269, 1985.
55. Klinger, H. P, and Shows, T B Suppression of tumorigenicity in somatic cell hybrids. II Human chromosomes implicated as suppressors of tumorigenicity in hybrids with Chinese hamster ovary cells. J. Natl. Cancer Inst., 71: 559-569, 1983.
56. Walker, C., Recio, L., Funaki, K., and Everitt, J. Cytogenetic and molecular correlates between rodent and human renal cell carcinoma. Prog Clin. Biol Res, 376: 289-302, 1992.