-
3
-
-
0030602838
-
Structural basis for the excision repair of alkylation-damadged DNA
-
Labahn J., Scharer O.D., Long A., Ezaz-Nikpay K., Verdine G.L., Ellenberger T.E. Structural basis for the excision repair of alkylation-damadged DNA. Cell. 86:1996;321-329.
-
(1996)
Cell
, vol.86
, pp. 321-329
-
-
Labahn, J.1
Scharer, O.D.2
Long, A.3
Ezaz-Nikpay, K.4
Verdine, G.L.5
Ellenberger, T.E.6
-
4
-
-
16044372779
-
Three-dimensional structure of a DNA repair enzyme 3-methyladenine DNA glycosylase II, from Escherichia coli
-
Yamagata Y., Kato M., Odawara K., Tokuno Y., Nakashima Y., Matsushima N., Yasumura K., Tomita K., Ihara K., Fujii Y.et al. Three-dimensional structure of a DNA repair enzyme 3-methyladenine DNA glycosylase II, from Escherichia coli. Cell. 86:1996;311-319.
-
(1996)
Cell
, vol.86
, pp. 311-319
-
-
Yamagata, Y.1
Kato, M.2
Odawara, K.3
Tokuno, Y.4
Nakashima, Y.5
Matsushima, N.6
Yasumura, K.7
Tomita, K.8
Ihara, K.9
Fujii, Y.10
-
5
-
-
0034708226
-
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
-
Bruner S.D., Norman D.P.G., Verdine G.L. Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature. 403:2000;859-866.
-
(2000)
Nature
, vol.403
, pp. 859-866
-
-
Bruner, S.D.1
Norman, D.P.G.2
Verdine, G.L.3
-
6
-
-
0037068446
-
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA damage
-
Trewick S., Henshaw T.F., Hausinger R.P., Lindahl T., Sedgwick B. Oxidative demethylation by Escherichia coli AlkB directly reverts DNA damage. Nature. 419:2002;174-178.
-
(2002)
Nature
, vol.419
, pp. 174-178
-
-
Trewick, S.1
Henshaw, T.F.2
Hausinger, R.P.3
Lindahl, T.4
Sedgwick, B.5
-
7
-
-
0037068433
-
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
-
Falnes P.O., Johansen R.F., Seeberg E. AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli. Nature. 419:2002;178-182.
-
(2002)
Nature
, vol.419
, pp. 178-182
-
-
Falnes, P.O.1
Johansen, R.F.2
Seeberg, E.3
-
8
-
-
0037168654
-
Reversal of DNA alkylation damage by two human dioxygenases
-
Duncan T., Trewick S.C., Koivisto P., Bates P.A., Lindahl T., Sedgwick B. Reversal of DNA alkylation damage by two human dioxygenases. Proc. Natl. Acad. Sci. USA. 99:2002;16660-16665.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 16660-16665
-
-
Duncan, T.1
Trewick, S.C.2
Koivisto, P.3
Bates, P.A.4
Lindahl, T.5
Sedgwick, B.6
-
9
-
-
0037456369
-
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA
-
Arnes Aas P., Otterlei M., Falnes P.O., Vågbo C.B., Skorpen F., Akari M., Sundheim O., Bjørås M., Slupphaug G., Seeberg E.et al. Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA. Nature. 421:2003;859-863.
-
(2003)
Nature
, vol.421
, pp. 859-863
-
-
Arnes Aas, P.1
Otterlei, M.2
Falnes, P.O.3
Vågbo, C.B.4
Skorpen, F.5
Akari, M.6
Sundheim, O.7
Bjørås, M.8
Slupphaug, G.9
Seeberg, E.10
-
10
-
-
0021894988
-
6-methylguanine-DNA methyltransferase in cell survivial, mutagenesis, and carcinogenesis
-
6-methylguanine-DNA methyltransferase in cell survivial, mutagenesis, and carcinogenesis. Mutat. Res. 145:1985;1-16.
-
(1985)
Mutat. Res.
, vol.145
, pp. 1-16
-
-
Yarosh, D.B.1
-
12
-
-
0002427798
-
Self-methylation by suicide DNA repair enzymes
-
W.K. Pair, & S. Kim. Boca Raton, FL: CRC Press. 285-304.pp
-
Demple B. Self-methylation by suicide DNA repair enzymes. Pair W.K., Kim S. Protein Methylation. 1990;CRC Press, Boca Raton, FL. 285-304.pp.
-
(1990)
Protein Methylation
-
-
Demple, B.1
-
13
-
-
0025195404
-
6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents
-
6-alkylguanine-DNA alkyltransferase. regulation and importance in response to alkylating carcinogenic and therapeutic agents Cancer Res. 50:1990;6119-6129.
-
(1990)
Cancer Res.
, vol.50
, pp. 6119-6129
-
-
Pegg, A.E.1
-
14
-
-
0027351670
-
Regulation of repair of alkylation damage in mammalian genomes
-
Mitra S., Kaina B. Regulation of repair of alkylation damage in mammalian genomes. Prog. Nucleic Acid Res. Mol. Biol. 44:1993;109-142.
-
(1993)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.44
, pp. 109-142
-
-
Mitra, S.1
Kaina, B.2
-
15
-
-
0037225952
-
A general method for the covalent labeling of fusion proteins with small molecules in vivo
-
Keppler A., Gendreizig S., Gronemeyer T., Pick H., Vogel H., Johnsson K. A general method for the covalent labeling of fusion proteins with small molecules in vivo. Nat. Biotechnol. 21:2003;86-89.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 86-89
-
-
Keppler, A.1
Gendreizig, S.2
Gronemeyer, T.3
Pick, H.4
Vogel, H.5
Johnsson, K.6
-
17
-
-
0022064910
-
6-alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea
-
6-alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea. Proc. Natl. Acad. Sci. USA. 82:1985;2985-2989.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 2985-2989
-
-
Brent, T.P.1
Houghton, P.J.2
Houghton, J.A.3
-
18
-
-
0031594831
-
6-methylguanine-DNA methyltransferase activity and sensitivity to cyclophosphamide and cisplatin in human lung tumor xenografts
-
6-methylguanine-DNA methyltransferase activity and sensitivity to cyclophosphamide and cisplatin in human lung tumor xenografts. Int. J. Cancer. 77:1998;919-922.
-
(1998)
Int. J. Cancer
, vol.77
, pp. 919-922
-
-
Mattern, J.1
Eichhorn, U.2
Kaina, B.3
Volm, M.4
-
19
-
-
0025941670
-
6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: The role of MGMT in protection against the genotoxic effects of alkylating agents
-
6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells. the role of MGMT in protection against the genotoxic effects of alkylating agents Carcinogenesis. 12:1991;1857-1867.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1857-1867
-
-
Kaina, B.1
Fritz, G.2
Mitra, S.3
Coquerelle, T.4
-
21
-
-
0034599723
-
Active and alkylated human AGT structures: A novel zinc site, inhibitor and extrahelical base binding
-
Daniels D.S., Mol C.D., Arvai A.S., Kanugula S., Pegg A.E., Tainer J.A. Active and alkylated human AGT structures. a novel zinc site, inhibitor and extrahelical base binding EMBO J. 19:2000;1719-1730.
-
(2000)
EMBO J.
, vol.19
, pp. 1719-1730
-
-
Daniels, D.S.1
Mol, C.D.2
Arvai, A.S.3
Kanugula, S.4
Pegg, A.E.5
Tainer, J.A.6
-
23
-
-
0031149139
-
How do DNA repair proteins locate damaged bases in the genome?
-
Verdine G.L., Bruner S.D. How do DNA repair proteins locate damaged bases in the genome? Chem. Biol. 4:1997;329-334.
-
(1997)
Chem. Biol.
, vol.4
, pp. 329-334
-
-
Verdine, G.L.1
Bruner, S.D.2
-
24
-
-
0028013240
-
The flip side of DNA methylation
-
Verdine G.L. The flip side of DNA methylation. Cell. 76:1994;197-200.
-
(1994)
Cell
, vol.76
, pp. 197-200
-
-
Verdine, G.L.1
-
27
-
-
0028010888
-
HhaI methyltransferase flips its target base out of the DNA helix
-
Klimasauskas S., Kumar S., Roberts S.J., Cheng X. HhaI methyltransferase flips its target base out of the DNA helix. Cell. 76:1994;357-369.
-
(1994)
Cell
, vol.76
, pp. 357-369
-
-
Klimasauskas, S.1
Kumar, S.2
Roberts, S.J.3
Cheng, X.4
-
28
-
-
0029068629
-
The crystal structure of HaeIII methyltransferase covalently complexed to DNA: An extrahelical cytosine and rearranged base pairing
-
Reinisch K.M., Chen L., Verdine G.L., Lipscomb W.N. The crystal structure of HaeIII methyltransferase covalently complexed to DNA. an extrahelical cytosine and rearranged base pairing Cell. 82:1995;143-153.
-
(1995)
Cell
, vol.82
, pp. 143-153
-
-
Reinisch, K.M.1
Chen, L.2
Verdine, G.L.3
Lipscomb, W.N.4
-
29
-
-
0029904839
-
A nucleotide-flipping mechanism from the structure of human uracil DNA glycosylase bound to DNA
-
Slupphaug G., Mol C.D., Kavil B., Arvai A.S., Krokan H.E., Tainer J.A. A nucleotide-flipping mechanism from the structure of human uracil DNA glycosylase bound to DNA. Nature. 384:1996;87-92.
-
(1996)
Nature
, vol.384
, pp. 87-92
-
-
Slupphaug, G.1
Mol, C.D.2
Kavil, B.3
Arvai, A.S.4
Krokan, H.E.5
Tainer, J.A.6
-
30
-
-
0000742057
-
Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis
-
Demple B., Sedgwick B., Robin P., Totty N., Waterfield M.D., Lindahl T. Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis. Proc. Natl. Acad. Sci. USA. 82:1985;2688-2692.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 2688-2692
-
-
Demple, B.1
Sedgwick, B.2
Robin, P.3
Totty, N.4
Waterfield, M.D.5
Lindahl, T.6
-
31
-
-
0032573488
-
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase at 2.7 Å resolution: Implications of comformational changes for polymerization and inhibition mechanism
-
Huang H., Chopra R., Verdine G.L., Harrison S.C. Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase at 2.7 Å resolution. implications of comformational changes for polymerization and inhibition mechanism Science. 282:1998;1669-1675.
-
(1998)
Science
, vol.282
, pp. 1669-1675
-
-
Huang, H.1
Chopra, R.2
Verdine, G.L.3
Harrison, S.C.4
-
32
-
-
0034111063
-
Trapping of a catalytic HIV reverse transcriptase-template:primer complex through a disulfide bond
-
Huang H., Harrison S.C., Verdine G.L. Trapping of a catalytic HIV reverse transcriptase-template:primer complex through a disulfide bond. Chem. Biol. 7:2000;355-364.
-
(2000)
Chem. Biol.
, vol.7
, pp. 355-364
-
-
Huang, H.1
Harrison, S.C.2
Verdine, G.L.3
-
33
-
-
12244275699
-
Trapping distinct structural states of a protein/DNA interaction through disulfide crosslinking
-
He C., Verdine G.L. Trapping distinct structural states of a protein/DNA interaction through disulfide crosslinking. Chem. Biol. 9:2002;1297-1303.
-
(2002)
Chem. Biol.
, vol.9
, pp. 1297-1303
-
-
He, C.1
Verdine, G.L.2
-
34
-
-
0001599016
-
4-(dimethylamino)-5-methylcytosine and 4-thiothymine
-
4-(dimethylamino)-5-methylcytosine and 4-thiothymine J. Org. Chem. 57:1992;3839-3845.
-
(1992)
J. Org. Chem.
, vol.57
, pp. 3839-3845
-
-
Xu, Y.Z.1
Zheng, Q.2
Swann, P.F.3
-
35
-
-
0025650326
-
Synthesis of functionally tethered oligonucleotides by the convertible nucleoside approach
-
MacMillan A.M., Verdine G.L. Synthesis of functionally tethered oligonucleotides by the convertible nucleoside approach. J. Org. Chem. 55:1990;5931-5933.
-
(1990)
J. Org. Chem.
, vol.55
, pp. 5931-5933
-
-
MacMillan, A.M.1
Verdine, G.L.2
-
36
-
-
0025969972
-
Engineering tethered DNA molecules by the convertible nucleoside approach
-
MacMillan A.M., Verdine G.L. Engineering tethered DNA molecules by the convertible nucleoside approach. Tetrahedron. 14:1991;2603-2616.
-
(1991)
Tetrahedron
, vol.14
, pp. 2603-2616
-
-
MacMillan, A.M.1
Verdine, G.L.2
-
37
-
-
0032581024
-
Nearest-neighbor thermodynamics of internal A:C mismatches in DNA: Sequence dependence and pH effects
-
Allawi H.T., SantaLucia J. Jr. Nearest-neighbor thermodynamics of internal A:C mismatches in DNA. sequence dependence and pH effects Biochemistry. 37:1998;9435-9444.
-
(1998)
Biochemistry
, vol.37
, pp. 9435-9444
-
-
Allawi, H.T.1
SantaLucia J., Jr.2
-
38
-
-
0032102940
-
Thermodynamics of internal C:T mismatches in DNA
-
Allawi H.T., SantaLucia J. Jr. Thermodynamics of internal C:T mismatches in DNA. Nucleic Acids Res. 26:1998;2694-2701.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 2694-2701
-
-
Allawi, H.T.1
SantaLucia J., Jr.2
-
41
-
-
0035501334
-
6-methylguanine is not affected by thymine base pairing and the presence of MMR proteins
-
6-methylguanine is not affected by thymine base pairing and the presence of MMR proteins. Mutat. Res. 487:2001;59-66.
-
(2001)
Mutat. Res.
, vol.487
, pp. 59-66
-
-
Lips, J.1
Kaina, B.2
-
42
-
-
0026611836
-
6-methylguanine:thymine mispairs in DNA by extracts of human cells
-
6-methylguanine:thymine mispairs in DNA by extracts of human cells. Biochemistry. 31:1992;7998-8008.
-
(1992)
Biochemistry
, vol.31
, pp. 7998-8008
-
-
Ullah, S.1
Day R.S. III2
|