Tyrosine phosphorylation in neutrophils from synovial fluid of patients with rheumatoid arthritis

British Journal of Rheumatology

Volumn 35, Issue 9, 1996, Pages 846-852

  Lloyds, D ^a   Davies, E V ^a   Williams, B D ^a   Hallett, M B ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Neutrophils; Rheumatoid arthritis; Tyrosine phosphorylation and priming

Indexed keywords

PROTEIN; TYROSINE;

ADULT; AGED; ARTICLE; BLOOD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOSOL; DOT HYBRIDIZATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOLECULAR WEIGHT; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID;

EID: 0029825958     PISSN: 02637103     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/35.9.846     Document Type: Article

References (39)

1. Vernon-Roberts B. The applied anatomy of the joint. In: Mason M, Currey HLF, eds. An introduction to clinical rheumatology. London: Pitman Medical, 1980:1-24.
2. Halliwell B, Gutteridge JMC. Free radicals in biology and medicine. Oxford: Clarendon Press, 1985.
3. Babior BM. Oxidants from phagocytes: agents of defence and destruction. Blood 1984;64:959-66.
4. Brown KA. The polymorphonuclear cell in rheumatoid arthritis. Br J Rheumatol 1988;27:150-5.
5. Hallett MB, Lloyds D. Neutrophil priming: The cellular signals which say "amber" but not "green". Immunol Today 1995;16:264-8.
6. McPhail LC, Clayton CC, Snyderman R. The NADPH oxidase of human polymorphonuclear leukocytes. Evidence for regulation by multiple signals. J Biol Chem 1984;259:5768-75.
7. Gale R, Bertouch JV, Bradley J, Roberts-Thomson PJ. Direct activation of neutrophil chemiluminescence by rheumatoid sera and synovial fluid. Ann Rheum Dis 1983;42:158-62.
8. Hollander AP, Dieppe PA, Atkins RM, Elson CJ. Hypothesis: cartilage catabolic co-factors in human arthritis. J Rheumatol 1993;20:223-4.
9. van Leeuwen MA, Westra J, Limburg PC, van Riel PL, van Rijswijk MH. Interleukin-6 in relation to other proinflammatory cytokines, chemotactic activity and neutrophil activation in rheumatoid synovial fluid. Ann Rheum Dis 1995;54:33-8.
10. Peichl P, Ceska M, Effenberger F, Haberhauer G, Broell H, Lindley IJ. Presence of NAP-1/IL-8 in synovial fluids indicates a possible pathogenic role in rheumatoid arthritis. Scand J Immunol 1991;34:333-9.
11. Fong KY, Boey ML, Koh WH, Feng PH. Cytokine concentrations in the synovial fluid and plasma of rheumatoid arthritis patients: correlation with bony erosions. Clin Exp Rheumatol 1994;12:55-8.
12. Hafstrom I, Gyllenhammar H, Palmblad J, Ringertz B. Substance P activates and modulates neutrophil oxidative metabolism and aggregation. J Rheumatol 1989; 16:1033-7.
13. Wiedermann CJ, Niedermuhlbichler M, Zilian U, Geissler D, Lindley I, Braunsteiner H. Priming of normal human neutrophils by tachykinins: tuftsin-like inhibition of in vitro chemotaxis stimulated by formylpeptide or interleukin-8. Reg Peptide 1991;36:359-68.
14. Menkes CJ, Renoux M, Laoussadi S, Mauborgne A, Bruxelle J, Cesselin F. Substance P levels in the synovium and synovial fluid from patients with rheumatoid arthritis and osteoarthritis. J Rheumatol 1993;20:714-7.
15. Arnalich F, de Miguel E, Perez-Ayala C et al. Neuropeptides and interleukin-6 in human joint inflammation: relationship between intraarticular substance P and interleukin-6 concentrations. Neurosci Lett 1994; 170:251-4.
16. Larsson J, Ekblom A, Henriksson K, Lundeberg T, Theodorsson E. Concentration of substance P, neurokinin A, calcitonin gene-related peptide, neuropeptide Y and vasoactive intestinal polypeptide in synovial fluid from knee joints in patients suffering from rheumatoid arthritis. Scand J Rheumatol 1991;20:326-35.
17. Cope AP, Aderka D, Doherty M et al. Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases. Arthritis Rheum 1992;35:1160-9.
18. Yen JH, Chen JR, Tsai WJ, Liu HW. Correlation of tumor necrosis factor alpha levels with disease activity of rheumatoid arthritis. Chin J Microbiol Immunol 1992;25:232-43.
19. Akimaru K, Utsumi T, Sato EF, Klostergaard J, Inoue M, Utsumi K. Role of tyrosyl phosphorylation in neutrophil priming by tumor necrosis factor-alpha and granulocyte colony stimulating factor. Arch Biochem Biophys 1992;298:703-9.
20. Lloyds D, Brindle NP, Hallett MB. Role of tyrosine phosphorylation of a 74 kDa protein in priming of neutrophils. Eur J Clin Invest 1993;23:187.
21. Lloyds D, Brindle NP, Hallett MB. Tyrosine phosphorylation of proteins during priming of neutrophils. Biochem Soc Trans 1993;21:436S.
22. Lloyds D, Brindle NP, Hallett MB. Priming of human neutrophils by tumour necrosis factor-alpha and substance P is associated with tyrosine phosphorylation. Immunology 1995;84:220-6.
23. Lloyds D, Hallett MB. Neutrophil 'priming' induced by orthovanadate: evidence of a role for tyrosine phosphorylation. Biochem Pharmacol 1994;48:15-21.
24. Boyum A. Isolation of mononuclear cells and granulocytes. Scand J Clin Lab Invest 1968;97:77-84.
25. 2+ dependent chemiluminescence in rat polymorphonuclear leukocytes by polystyrene beads and the non lytic action of complement. Immunology 1981;44:569-76.
26. 2+ and oxidase activition in rat neutrophils. Cell Calcium 1988;9:17-26.
27. Brindle NP, Tavare JM, Dickens M, Whittaker J, Siddle K. Anti-(insulin receptor) monoclonal antibody-stimulated tyrosine phosphorylation in cells transfected with human insulin receptor cDNA. Biochem J 1990;268:615-20.
28. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
29. Frackelton AR, Posner M, Kannan B, Mermelstein F. Generation of monoclonal antibodies and their use for affinity purification of phospho-tyrosine containing proteins. Methods Enzymol 1991;201:79-92.
30. Lloyds D. Mechanisms of neutrophil priming in inflammation. PhD Thesis, University of Wales, 1995.
31. Thompson HL, Shiroo M, Saklatvala J. The chemotactic factor N-formylmethionyl-leucyl-phenylalanine activates MAP kinase and a MAP kinase kinase in polymorphonuclear leucocytes. Biochem J 1993;290:483-8.
32. Dusi S, Donini M, Rossi F. Tyrosine phosphorylation and activation of NADPH oxidase in human neutrophils: a possible role for MAP kinases and a 75 KDa protein. Biochem J 1994;304:247-51.
33. Lloyds D, Hallett MB. Is raf-1 the 74kDa signalling molecule in neutrophils? Biochem J 1995;308:1037.
34. Elliot MJ, Maini RN, Feldman M et al. Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor-α versus placebo in rheumatoid arthritis. Lancet 1994;344:1105-10.
35. Elliot MJ, Maini RN, Feldman M, Long-Fox A, Charles P, Bijl H, Woody JN. Repeated therapy with monoclonal antibody to tumour necrosis factor-α in patients with rheumatoid arthritis. Lancet 1994;344:1125-7.
36. Deal CL, Schnitzer TJ, Lipstein E et al. Treatment of arthritis with topical capsaicin: a double-blind trial. Clin Ther 1991;13:383-5.
37. Rumsfield JA, West DP. Topical capsaicin in dermatologic and peripheral pain disorders. Ann Pharmacother 1991;25:381-7.
38. Nurcombe HL, Bucknall RC, Edwards SW. Neutrophils isolated from the synovial fluid of patients with rheumatoid arthritis: priming and activation in vivo. Ann Rheum Dis 1991;50:147-53.
39. Marhoffer W, Stein M, Keck K, Federlin K. Evidence of impaired polymorphonuclear leukocyte phagocytic functions and chemiluminescence response in rheumatoid-arthritis. Rheumatol Int 1994;13:251-5.