The role of dairy ingredients in enhancing immunity

Australian Journal of Dairy Technology

Volumn 58, Issue 2, 2003, Pages 135-139

  Stevenson, Lesley ^a   Knowles, Graham ^b  

^a Numico Research Australia   (Australia)

^b Wakefield Hospital   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; BIOASSAY; HEALTH CARE; IMMUNOLOGY; PATHOLOGY; PROTEINS; QUALITY CONTROL;

FOOD SAFETY;

DAIRY PRODUCTS;

ANIMALIA;

EID: 0141595868     PISSN: 00049433     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (64)

1. Aderem, A. and Ulevitch, R.J. (2000), Toll-like receptors in the induction of the innate immune response. Nature 406, 782-7.
2. Akin, D.T., Lu, M.Q., Lu, S.J., Kendall, S., Rundegren, J. and Arnold, R.R. (1994), Bactericidal activity of different forms of lactoferrin. Adv. Exp. Med. Biol. 357, 61-70.
3. Berkhout, B., Derksen, G.C., Back, N.K., Klaver, B., de Kruif, C.G. and Visser, S. (1997), Structural and functional analysis of negatively charged milk proteins with anti-HIV activity. AIDS Res. Hum. Retroviruses 13, 1101-1107.
4. Boehm, G. and Stahl, B. (2003), Oligosaccharides. In: Functional Dairy Products (Eds. Mattila-Sanholm, T. and Saarrela, M), CRC Press, England, pp 203-243.
5. Bounous, G. (2000), Whey protein concentrate (WPC) and glutathione modulation in cancer treatment. Anticancer Res. 20, 4785-4792.
6. Bounous, G., Stevenson, M.M. and Kongshavn, P.A. (1981), Influence of dietary lactalbumin hydrolysate on the immune system of mice and resistance to salmonellosis. J. Infect. Dis. 144, 281.
7. Bounous, G. and Kongshavn, P.A. (1982), Influence of dietary proteins on the immune system of mice. J. Nutr. 112, 1747-1755.
8. Bounous, G. and Kongshavn, P.A. (1985), Differential effect of dietary protein type on the B-cell and T-cell immune responses in mice. J. Nutr. 115, 1403-1408.
9. Bounous, G., Kongshavn, P.A. and Gold, P. (1988a), The immunoenhancing property of dietary whey protein concentrate. Clin. Invest. Med. 11, 271-278.
10. Bounous, G., Papenburg, R., Kongshavn, P.A., Gold, P. and Fleiszer, D. (1988b), Dietary whey protein inhibits the development of dimethylhydrazine induced malignancy. Clin. Invest. Med. 11, 213-217.
11. Brinkworth G, and Buckley J.D. (2003), Concentrated bovine colostrum protein supplementation reduces the incidence of self-reported symptoms of upper respiratory tract infection in adult males. European Journal of Nutrition, In press.
12. Campbell, M.A.F., Kolev, Y. Stevenson, L.M., van den Berg, J., Tran, C.D. Davidson G.P. and Butler R.N. (2003), Effect of hydrolysed lactoferrin in Helicobacter pylori-infected mice. Personal communication.
13. Carver, J.D., Salvioli, G.P., Vigi, V. and Zetterstrom, R. (1999), Dietary nucleotides: effects on the immune and gastrointestinal systems. Acta Paediatrica 88, (Sup 430):83-88.
14. Chevalier, P., Sevilla, R., Zalles, L., Sejas, E., Belmonte, G., Parent, G. and Jambon, B. (1996), [Immuno-nutritional recovery of children with severe malnutrition]. Sante 6, 201-208.
15. Cross, M.L. and Gill, H.S. (2000), Immunomodulatory properties of milk. Br. J. Nutr. 84 Suppl 1, S81-89.
16. Dial, E.J., Hall, L.R., Serna, H., Romero, J.J., Fox, J.G. and Lichtenberger, L.M. (1998), Antibiotic properties of bovine lactoferrin on Helicobacter pylori. Dig. Dis. Sci. 43, 2750-2756.
17. Elitsur, Y. and Luk, G.D. (1991), Beta-casomorphin (BCM) and human colonic lamina propria lymphocyte proliferation. Clin. Exp. Immunol. 85, 493-497.
18. Fell, J.M., Paintin, M., Arnaud-Battandier, F., Beattie, R.M., Hollis, A., Kitching, P., Donnet-Hughes, A., MacDonald, T.T. and Walker-Smith, J.A. (2000), Mucosal healing and a fall in mucosal pro-inflammatory cytokine mRNA induced by a specific oral polymeric diet in paediatric Crohn's disease. Aliment. Pharmacol. Ther. 14, 281-289.
19. Filipp, D., Alizadeh-Khiavi, K., Richardson, C., Palma, A., Paredes, N., Takeuchi, O., Akira, S. and Julius, M. (2001), Soluble CD14 enriched in colostrum and milk induces B cell growth and differentiation. Proc. Natl. Acad. Sci. USA 98, 603-608.
20. Gill, H.S., Doull, F., Rutherfurd, K.J. and Cross, M.L. (2000), Immunoregulatory peptides in bovine milk. Br. J. Nutr. 84 Suppl 1, S111-117.
21. Hakansson, A., Svensson, M., Mossberg, A.K., Sabharwal, H., Linse, S., Lazou, I., Lonnerdal, B. and Svanborg, C. (2000), A folding variant of alpha-lactalbumin with bactericidal activity against Streptococcus pneumoniae [published erratum appears in Mol. Microbiol. 2000 36, 247]. Mol 35, 589-600.
22. Harada, E., Itoh, Y., Sitizyo, K., Takeuchi, T., Araki, Y. and Kitagawa, H. (1999), Characteristic transport of lactoferrin from the intestinal lumen into the bile via the blood in piglets. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 124, 321-327.
23. He, F., Tuomola, E., Arvilommi, H. and Salminen, S. (2001), Modulation of human humoral immune response through orally administered bovine colostrum. FEMS Immunol. Med. Microbiol. 31, 93-96.
24. Houdijk, A.P., Rijnsburger, E.R., Jansen, J., Wesdorp, R.I., Weiss, J.K., McCamish, M.A., Teerlink, T., Meuwissen, S.G., Haarman, H.J., Thijs, L.G. and van Leeuwen, P.A. (1998), Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma. Lancet 352, 772-776.
25. Ishizaka, S., Kimoto, M., Tsujii, T. and Saito, S. (1994), Antibody production system modulated by oral administration of human milk and TGF-beta. Cell. Immunol. 159, 77-84.
26. Jia, H.P., Starner, T., Ackermann, M., Kirby, P., Tack, B.F. and McCray, P.B. Jr (2001), Abundant human beta-defensin-1 expression in milk and mammary gland epithelium. J. Pediatr. 138, 109-12.
27. Kayser, H. and Meisel, H. (1996), Stimulation of human peripheral blood lymphocytes by bioactive peptides derived from bovine milk proteins. FEBS Lett 383, 18-20.
28. Kennedy, R.S., Konok, G.P., Bounous, G., Baruchel, S. and Lee, T.D. (1995), The use of a whey protein concentrate in the treatment of patients with metastatic carcinoma: a phase I-II clinical study. Anticancer Res 15, 2643-2649.
29. Kim, P.H., Eckmann, L., Lee, W.J., Han, W. and Kagnoff, M.F. (1998), Cholera toxin and cholera toxin B subunit induce IgA switching through the action of TGF-beta 1. J. Immunol. 160, 1198-1203.
30. Korhonen, H., Marnila, P. and Gill, H.S. (2000), Bovine milk antibodies for health. Br. J. Nutr. 84 Suppl 1, S135-146.
31. Kutzemeier, T. (1998), Genetic engineering: innovation and the improvement of functional milk products. Deutsche Milchwirtschaft 49, 142-144.
32. Lahov, E. and Regelson, W. (1996), Antibacterial and immunostimulating casein-derived substances from milk: casecidin, isracidin peptides. Food Chem. Toxicol. 34, 131-145.
33. Lillard, J.W. Jr, Boyaka, P.N., Chertov, O., Oppenheim, J.J. and McGhee, J.R. (1999), Mechanisms for induction of acquired host immunity by neutrophil peptide defensins. Proc. Natl. Acad. Sci. U S A 96, 651-656.
34. Martin-Burriel, I., Osta, R., Barendse, W. and Zaragoza, P. (1997), New polymorphism and linkage mapping of the bovine lactotransferrin gene. Mamm. Genome 8, 704-705.
35. Mattsby-Baltzer, I., Roseanu, A., Motas, C., Elverfors, J., Engberg, I. and Hanson, L.A. (1996), Lactoferrin or a fragment thereof inhibits the endotoxin-induced interleukin-6 response in human monocytic cells. Pediatr. Res. 40, 257-262.
36. McIntosh, G.H., Regester, G.O., Le Leu, R.K., Royle, P.J. and Smithers, G.W. (1995), Dairy proteins protect against dimethylhydrazine-induced intestinal cancers in rats. J. Nutr. 125, 809-816.
37. Meisel, H. (1997), Biochemical properties of regulatory peptides derived from milk proteins. Biopolymers 43, 119-128.
38. Meisel, H. and FitzGerald, R.J. (2000), Opioid peptides encrypted in intact milk protein sequences. Br. J. Nutr. 84 Suppl 1, S27-31.
39. Migliore-Samour, D. and Jolles, P. (1988), Casein, a prohormone with an immunomodulating role for the newborn? Experientia 44, 188-193.
40. Miyauchi, H., Kaino, A., Shinoda, I., Fukuwatari, Y. and Hayasawa, H. (1997), Immunomodulatory effect of bovine lactoferrin pepsin hydrolysate on murine splenocytes and Peyer's patch cells. J. Dairy Sci. 80, 2330-2339.
41. Otani, H. and Hata, I. (1995), Inhibition of proliferative responses of mouse spleen lymphocytes and rabbit Peyer's patch cells by bovine milk caseins and their digests. J. Dairy Res. 62, 339-348.
42. Owens, W.E. and Nickerson, S.C. (1989), Evaluation of an anti-inflammatory factor derived from hyperimmunized cows. Proc. Soc. Exp. Biol. Med. 190, 79-86.
43. Parodi, P.W. (1997), Cows' milk fat components as potential anticarcinogenic agents. J. Nutr. 127, 1055-1060.
44. Pecquet, S., Bovetto, L., Maynard, F. and Fritsche, R. (2000), Peptides obtained by tryptic hydrolysis of bovine beta-lactoglobulin induce specific oral tolerance in mice. J Allergy Clin Immunol 105, 514-521.
45. Romond, M.B., Ais, A., Guillemot, F., Bounouader, R., Cortot, A. and Romond, C. (1998), Cell-free whey from milk fermented with Bifidobacterium breve C50 used to modify the colonic microflora of healthy subjects. J. Dairy Sci. 81, 1229-1235.
46. Rump, J.A., Arndt, R., Arnold, A., Bendick, C., Dichtelmuller, H., Franke, M., Helm, E.B., Jager, H., Kampmann, B., Kolb, P. et al. (1992), Treatment of diarrhoea in human immunodeficiency virus-infected patients with immunoglobulins from bovine colostrum. Clin. Investig. 70, 588-594.
47. Schlimme, E., Martin, D. and Meisel, H. (2000), Nucleosides and nucleotides: natural bioactive substances in milk and colostrum. Br. J. Nutr. 84 Suppl 1, S59-68.
48. Shankar, A.H., Genton, B., Semba, R.D., Baisor, M., Paino, J., Tamja, S., Adiguma, T., Wu, L., Rare, L., Tielsch, J.M., Alpers, M.P. and West, K.P. Jr (1999), Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: a randomised trial. Lancet 354, 203-209.
49. Shinoda, I., Takase, M., Fukuwatari, Y., Shimamura, S., Koller, M. and Konig, W. (1996), Effects of lactoferrin and lactoferricin on the release of interleukin 8 from human polymorphonuclear leukocytes. Biosci. Biotechnol. Biochem. 60, 521-523.
50. Stephan, W., Dichtelmuller, H. and Lissner, R. (1990), Antibodies from colostrum in oral immunotherapy. J. Clin. Chem. Clin. Biochem. 28, 19-23.
51. Stoeck, M., Ruegg, C., Miescher, S., Carrel, S., Cox, D., Von Fliedner, V. and Alkan, S. (1989), Comparison of the immunosuppressive properties of milk growth factor and transforming growth factors b1 and b2. J. Immunol. 143, 3258-3265.
52. Sutas, Y., Soppi, E., Korhonen, H., Syvaoja, E.L., Saxelin, M., Rokka, T. and Isolauri, E. (1996), Suppression of lymphocyte proliferation in vitro by bovine caseins hydrolyzed with Lactobacillus casei GG-derived enzymes. J. Allergy Clin. Immunol. 98, 216-224.
53. Tani, K., Murphy, W.J., Chertov, O., Salcedo, R., Koh, C.Y., Utsunomiya, I., Funakoshi, S., Asai, O., Herrmann, S.H., Wang, J.M., Kwak, L.W. and Oppenheim, J.J. (2000), Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens. Int. Immunol. 12, 691-700.
54. Wada, T., Aiba, Y., Shimizu, K., Takagi, A., Miwa, T. and Koga, Y. (1999), The therapeutic effect of bovine lactoferrin in the host infected with Helicobacter pylori. Scand. J. Gastroenterol. 34, 238-243.
55. Watson, D.L., Francis, G.L. and Ballard, F.J. (1992), Factors in ruminant colostrum that influence cell growth and murine IgE antibody responses. J. Dairy Res. 59, 369-380.
56. Werner, G.H. (1986), Synthetic immunostimulants (excluding sulfur-containing compounds). Comp. Immunol. Microbiol. Infect. Dis. 9, 131-136.
57. Wieczorek, Z., Zimecki, M., Slon, J.J. and Siemion, I.Z. (1994), The immunomodulatory activity of tetra- and tripeptides of tuftsin- kentsin group. Peptides 15, 215-221.
58. Wong, C.W., Seow, H.F., Husband, A.J., Regester, G.O. and Watson, D.L. (1997), Effects of purified bovine whey factors on cellular immune functions in ruminants. Vet. Immunol. Immunopathol. 56, 85-96.
59. Wong, C.W., Seow, H.F., Liu, A.H., Husband, A.J., Smithers, G.W. and Watson, D.L. (1996), Modulation of immune responses by bovine β-casein. Immunol. Cell Biol. 74, 323-329.
60. Wong, C.W. and Watson, D.L. (1995), Immunomodulatory effects of dietary whey proteins in mice. J. Dairy Res. 62, 359-368.
61. Yun, S.S., Sugita-Konishi, Y., Kumagai, S. and Yamauchi, K. (1996), Isolation of mitogenic glycophosphopeptides from cheese whey protein concentrate. Biosci. Biotechnol. Biochem. 60, 429-433.
62. Zimecki, M. and Kruzel, M.L. (2000), Systemic or local co-administration of lactoferrin with sensitizing dose of antigen enhances delayed type hypersensitivity in mice. Immunol. Lett. 74, 183-8.
63. Zimecki, M., Spiegel, K., Wlaszczyk, A., Kubler, A. and Kruzel, M.L. (1999), Lactoferrin increases the output of neutrophil precursors and attenuates the spontaneous production of TNF-alpha and IL-6 by peripheral blood cells. Arch. Immunol. Ther. Exp (Warsz) 47, 113-118.
64. Zimecki, M., Stepniak, D., Szynol, A. and Kruzel, M.L. (2001), Lactoferrin regulates proliferative response of human peripheral blood mononuclear cells to phytohemagglutinin and mixed lymphocyte reaction. Arch. Immunol. Ther. Exp. (Warsz) 49, 147-154.