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Volumn 12, Issue 5, 2000, Pages 691-700

Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens

Author keywords

Antibody formation; Cytokine; IFN ; IL 4; Tumor antigen

Indexed keywords

ALUMINUM HYDROXIDE; DEFENSIN; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 4; KEYHOLE LIMPET HEMOCYANIN; TUMOR ANTIGEN;

EID: 0034061579     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/12.5.691     Document Type: Article
Times cited : (195)

References (49)
  • 1
    • 0343492953 scopus 로고
    • The mechanical responses of white blood cells
    • Gallin, J. I., Goldstein, I. M. and Snyderman, R., eds, Raven Press, New York
    • Stossel, T. P. 1992. The mechanical responses of white blood cells. In Gallin, J. I., Goldstein, I. M. and Snyderman, R., eds, Inflammation: Basic Principles and Clinical Correlates, 2nd edn. Raven Press, New York.
    • (1992) Inflammation: Basic Principles and Clinical Correlates, 2nd Edn.
    • Stossel, T.P.1
  • 2
    • 0001902788 scopus 로고
    • Neutrophil phagocytosis and killing: Normal function and microbial evasion
    • Wheeler, J. G. and Abramson, J. S., eds, IRL Press at Oxford University Press, Oxford
    • Verhoef, J. and Visser, M. R. 1993. Neutrophil phagocytosis and killing: normal function and microbial evasion. In Wheeler, J. G. and Abramson, J. S., eds, The Neutrophil, IRL Press at Oxford University Press, Oxford.
    • (1993) The Neutrophil
    • Verhoef, J.1    Visser, M.R.2
  • 3
    • 0025107597 scopus 로고
    • Antibiotic proteins of human neutrophils
    • Spitznagel, J. K. 1990. Antibiotic proteins of human neutrophils. J. Clin. Invest. 86:1381.
    • (1990) J. Clin. Invest. , vol.86 , pp. 1381
    • Spitznagel, J.K.1
  • 4
    • 0030861378 scopus 로고    scopus 로고
    • Antimicrobial peptides of phagocytes and epithelia
    • Ganz, T. and Weiss, J. 1997. Antimicrobial peptides of phagocytes and epithelia. Semin. Hematol. 34:343.
    • (1997) Semin. Hematol. , vol.34 , pp. 343
    • Ganz, T.1    Weiss, J.2
  • 5
    • 0030914439 scopus 로고    scopus 로고
    • Localization of human intestinal defensin 5 in Paneth cell granules
    • Porter, E. M., Liu, L., Oren, A., Anton, P. A. and Ganz, T. 1997. Localization of human intestinal defensin 5 in Paneth cell granules. Infect. Immun. 65:2389.
    • (1997) Infect. Immun. , vol.65 , pp. 2389
    • Porter, E.M.1    Liu, L.2    Oren, A.3    Anton, P.A.4    Ganz, T.5
  • 6
    • 0009464172 scopus 로고
    • Antibiotic proteins of human polymorphonuclear leukocytes
    • published erratum appears in Proc. Natl Acad. Sci. USA 1989; 86(24):10133
    • Gabay, J. E., Scott, R. W., Campanelli, D., Griffith, J., Wilde, C., Marra, M. N., Seeger, M. and Nathan, C. F. 1989. Antibiotic proteins of human polymorphonuclear leukocytes [published erratum appears in Proc. Natl Acad. Sci. USA 1989; 86(24):10133]. Proc. Natl Acad. Sci. USA 86:5610.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 5610
    • Gabay, J.E.1    Scott, R.W.2    Campanelli, D.3    Griffith, J.4    Wilde, C.5    Marra, M.N.6    Seeger, M.7    Nathan, C.F.8
  • 7
    • 0024391711 scopus 로고
    • Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity
    • Lehrer, R. I., Barton, A., Daher, K. A., Harwig, S. S., Ganz, T. and Selsted, M. E. 1989. Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity. J. Clin. Invest. 84:553.
    • (1989) J. Clin. Invest. , vol.84 , pp. 553
    • Lehrer, R.I.1    Barton, A.2    Daher, K.A.3    Harwig, S.S.4    Ganz, T.5    Selsted, M.E.6
  • 8
    • 0024797674 scopus 로고
    • Monocyte-chemotactic activity of defensins from human neutrophils
    • Territo, M. C., Ganz, T., Selsted, M. E. and Lehrer, R. 1989. Monocyte-chemotactic activity of defensins from human neutrophils. J. Clin. Invest. 84:2017.
    • (1989) J. Clin. Invest. , vol.84 , pp. 2017
    • Territo, M.C.1    Ganz, T.2    Selsted, M.E.3    Lehrer, R.4
  • 9
    • 0030038197 scopus 로고    scopus 로고
    • Identification of defensin-1, defensin-2 and CAP37/ azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils
    • Chertov, O., Michiel, D. F., Xu, L., Wang, J. M., Tani, K., Murphy, W. J., Longo, D. L., Taub, D. D. and Oppenheim, J. J. 1996. Identification of defensin-1, defensin-2 and CAP37/ azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils. J. Biol. Chem. 271:2935.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2935
    • Chertov, O.1    Michiel, D.F.2    Xu, L.3    Wang, J.M.4    Tani, K.5    Murphy, W.J.6    Longo, D.L.7    Taub, D.D.8    Oppenheim, J.J.9
  • 12
    • 0028329177 scopus 로고
    • Effects of IL-12 on helper T cell-dependent immune responses in vivo
    • McKnight, A. J., Zimmer, G. J., Fogelman, I., Wolf, S. F. and Abbas, A. K. 1994. Effects of IL-12 on helper T cell-dependent immune responses in vivo. J. Immunol. 152:2172.
    • (1994) J. Immunol. , vol.152 , pp. 2172
    • McKnight, A.J.1    Zimmer, G.J.2    Fogelman, I.3    Wolf, S.F.4    Abbas, A.K.5
  • 13
    • 0029099861 scopus 로고
    • Interleukin-12 treatment during immunization elicits a T helper cell type 1-like immune response in mice challenged with respiratory syncytial virus and improves vaccine immunogenicity
    • Tang, Y. W. and Graham, B. S. 1995. Interleukin-12 treatment during immunization elicits a T helper cell type 1-like immune response in mice challenged with respiratory syncytial virus and improves vaccine immunogenicity. J. Infect. Dis. 172:734.
    • (1995) J. Infect. Dis. , vol.172 , pp. 734
    • Tang, Y.W.1    Graham, B.S.2
  • 14
    • 0025819340 scopus 로고
    • Induction of interferon gamma production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers
    • Chan, S. H., Perussia, B., Gupta, J. W., Kobayashi, M., Pospisil, M., Young, H. A., Wolf, S. F., Young, D., Clark, S. C. and Trinchieri, G. 1991. Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J. Exp. Med. 173:869.
    • (1991) J. Exp. Med. , vol.173 , pp. 869
    • Chan, S.H.1    Perussia, B.2    Gupta, J.W.3    Kobayashi, M.4    Pospisil, M.5    Young, H.A.6    Wolf, S.F.7    Young, D.8    Clark, S.C.9    Trinchieri, G.10
  • 15
    • 0030293445 scopus 로고    scopus 로고
    • IL-12 enhances vaccine-induced immunity to schistosomes by augmenting both humoral and cell-mediated immune responses against the parasite
    • Wynn, T. A., Reynolds, A., James, S., Cheever, A. W., Caspar, P., Hieny, S., Jankovic, D., Strand, M. and Sher, A. 1996. IL-12 enhances vaccine-induced immunity to schistosomes by augmenting both humoral and cell-mediated immune responses against the parasite. J. Immunol. 157:4068.
    • (1996) J. Immunol. , vol.157 , pp. 4068
    • Wynn, T.A.1    Reynolds, A.2    James, S.3    Cheever, A.W.4    Caspar, P.5    Hieny, S.6    Jankovic, D.7    Strand, M.8    Sher, A.9
  • 16
    • 0018392189 scopus 로고
    • Induction of secretion of igm from cells of the B cell line 38c-13 by somatic cell hybridization
    • Eshhar, Z. Blatt, C., Bergman, Y. and Heimovich, J. 1979. Induction of secretion of IgM from cells of the B cell line 38c-13 by somatic cell hybridization. J. Immunol. 122:2430.
    • (1979) J. Immunol. , vol.122 , pp. 2430
    • Eshhar, Z.1    Blatt, C.2    Bergman, Y.3    Heimovich, J.4
  • 17
    • 0025936007 scopus 로고
    • Antigen dose-dependent regulation of B epsilon-memory cell expression
    • Kolbe, L., Heusser, C. and Kolsch, E. 1991. Antigen dose-dependent regulation of B epsilon-memory cell expression. Int. Arch. Allergy Appl. Immunol. 95:202.
    • (1991) Int. Arch. Allergy Appl. Immunol. , vol.95 , pp. 202
    • Kolbe, L.1    Heusser, C.2    Kolsch, E.3
  • 18
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55
    • Mosmann, T.1
  • 19
    • 0029744442 scopus 로고    scopus 로고
    • Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/ macrophage colony-stimulating factor primes mice for a protective T-cell response
    • Kwak, L. W., Young, H. A., Pennington, R. W. and Weeks, S. D. 1996. Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/ macrophage colony-stimulating factor primes mice for a protective T-cell response. Proc. Natl Acad. Sci. USA 93:10972.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 10972
    • Kwak, L.W.1    Young, H.A.2    Pennington, R.W.3    Weeks, S.D.4
  • 20
    • 0017684604 scopus 로고
    • Characterization of a carcinogen-induced murine b lymphocyte cell line of C3H/eB origin
    • Bergman, Y. and Haimovich, J. 1977. Characterization of a carcinogen-induced murine B lymphocyte cell line of C3H/eB origin. Eur. J. Immunol. 7:413.
    • (1977) Eur. J. Immunol. , vol.7 , pp. 413
    • Bergman, Y.1    Haimovich, J.2
  • 21
    • 0023839463 scopus 로고
    • IFN-gamma regulates the isotypes of ig secreted during in vivo humoral immune responses
    • Finkelman, F. D., Katona, I. M., Mosmann, T. R. and Coffman, R. L. 1988. IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses. J. Immunol. 140:1022.
    • (1988) J. Immunol. , vol.140 , pp. 1022
    • Finkelman, F.D.1    Katona, I.M.2    Mosmann, T.R.3    Coffman, R.L.4
  • 23
    • 0023890722 scopus 로고
    • Heterogeneity of helper/inducer T lymphocytes. II. Effects of interleukin 4-and interleukin 2-producing T cell clones on resting B lymphocytes
    • Boom, W. H., Liano, D. and Abbas, A. K. 1988. Heterogeneity of helper/inducer T lymphocytes. II. Effects of interleukin 4-and interleukin 2-producing T cell clones on resting B lymphocytes. J. Exp. Med. 167:1350.
    • (1988) J. Exp. Med. , vol.167 , pp. 1350
    • Boom, W.H.1    Liano, D.2    Abbas, A.K.3
  • 24
    • 0016822166 scopus 로고
    • Antibody to a molecularly-defined antigen confined to a tumour cell surface
    • Stevenson, G. T. and Stevenson, F. K. 1975. Antibody to a molecularly-defined antigen confined to a tumour cell surface. Nature 254:714.
    • (1975) Nature , vol.254 , pp. 714
    • Stevenson, G.T.1    Stevenson, F.K.2
  • 26
    • 0025367884 scopus 로고
    • Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of antitumor immunity
    • Campbell, M. J., Esserman, L., Byars, N. E., Allison, A. C. and Levy, R. 1990. Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of antitumor immunity. J. Immunol. 145:1029.
    • (1990) J. Immunol. , vol.145 , pp. 1029
    • Campbell, M.J.1    Esserman, L.2    Byars, N.E.3    Allison, A.C.4    Levy, R.5
  • 27
    • 0029921168 scopus 로고    scopus 로고
    • T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo
    • Taub, D. D., Anver, M., Oppenheim, J. J., Longe, D. L. and Murphy, W. J. 1996. T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo. J. Clin. Invest. 97:1931.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1931
    • Taub, D.D.1    Anver, M.2    Oppenheim, J.J.3    Longe, D.L.4    Murphy, W.J.5
  • 28
    • 0027191220 scopus 로고
    • Modulation of in vivo immune response by selective depletion of neutrophils using a monoclonal antibody, RP-3. I. Inhibition by RP-3 treatment of the priming and effector phases of delayed type hypersensitivity to sheep red blood cells in rats
    • Kudo, C., Yamashita, T., Araki, A., Terashita, M., Watanabe, T., Atsumi, M., Tamura, M. and Sendo, F. 1993. Modulation of in vivo immune response by selective depletion of neutrophils using a monoclonal antibody, RP-3. I. Inhibition by RP-3 treatment of the priming and effector phases of delayed type hypersensitivity to sheep red blood cells in rats. J. Immunol. 150:3728.
    • (1993) J. Immunol. , vol.150 , pp. 3728
    • Kudo, C.1    Yamashita, T.2    Araki, A.3    Terashita, M.4    Watanabe, T.5    Atsumi, M.6    Tamura, M.7    Sendo, F.8
  • 29
    • 0027256501 scopus 로고
    • Modulation of in vivo immune response by selective depletion of neutrophils using a monoclonal antibody, RP-3. II. Inhibition by RP-3 treatment of mononuclear leukocyte recruitment in delayed-type hypersensitivity to sheep red blood cells in rats
    • Kudo, C., Yamashita, T., Terashita, M. and Sendo, F. 1993. Modulation of in vivo immune response by selective depletion of neutrophils using a monoclonal antibody, RP-3. II. Inhibition by RP-3 treatment of mononuclear leukocyte recruitment in delayed-type hypersensitivity to sheep red blood cells in rats. J. Immunol. 150:3739.
    • (1993) J. Immunol. , vol.150 , pp. 3739
    • Kudo, C.1    Yamashita, T.2    Terashita, M.3    Sendo, F.4
  • 32
    • 0029021419 scopus 로고
    • IL-12 stimulates an antiviral type 1 cytokine response but lacks adjuvant activity in IFN-gamma-receptor-deficient mice
    • Schijns, V. E., Haagmans, B. L. and Horzinek, M. C. 1995. IL-12 stimulates an antiviral type 1 cytokine response but lacks adjuvant activity in IFN-gamma-receptor-deficient mice. J. Immunol. 155:2525.
    • (1995) J. Immunol. , vol.155 , pp. 2525
    • Schijns, V.E.1    Haagmans, B.L.2    Horzinek, M.C.3
  • 33
    • 0029156730 scopus 로고
    • Secondary response to listeria infection requires IFN-gamma but is partially independent of IL-12
    • Tripp, C. S., Kanagawa, O. and Unanue, E. R. 1995. Secondary response to Listeria infection requires IFN-gamma but is partially independent of IL-12. J. Immunol. 155:3427.
    • (1995) J. Immunol. , vol.155 , pp. 3427
    • Tripp, C.S.1    Kanagawa, O.2    Unanue, E.R.3
  • 35
    • 0344780824 scopus 로고    scopus 로고
    • Interleukin-12 as an adjuvant for an antischistosome vaccine consisting of adult worm antigens: Protection of rats from cercarial challenge
    • Bungiro, R. D., Jr, Goldberg, M., Suri, P. K. and Knopf, P. M. 1999. Interleukin-12 as an adjuvant for an antischistosome vaccine consisting of adult worm antigens: protection of rats from cercarial challenge. Infect. Immun. 67:2340.
    • (1999) Infect. Immun. , vol.67 , pp. 2340
    • Bungiro R.D., Jr.1    Goldberg, M.2    Suri, P.K.3    Knopf, P.M.4
  • 36
    • 0024467154 scopus 로고
    • Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
    • Kobayashi, M., Fitz, L., Ryan, M., Hewick, R. M., Clark, S. C., Chan, S., Loudon, R., Sherman, F., Perussia, B. and Trinchieri, G. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J. Exp. Med. 170:827.
    • (1989) J. Exp. Med. , vol.170 , pp. 827
    • Kobayashi, M.1    Fitz, L.2    Ryan, M.3    Hewick, R.M.4    Clark, S.C.5    Chan, S.6    Loudon, R.7    Sherman, F.8    Perussia, B.9    Trinchieri, G.10
  • 37
    • 0028104745 scopus 로고
    • Regulation of human igg subclass production by cytokines. IFN-gamma and IL-6 act antagonistically in the induction of human IgG1 but additively in the induction of IgG2
    • Kawano, Y., Noma, T. and Yata, J. 1994. Regulation of human IgG subclass production by cytokines. IFN-gamma and IL-6 act antagonistically in the induction of human IgG1 but additively in the induction of IgG2. J. Immunol. 153:4948.
    • (1994) J. Immunol. , vol.153 , pp. 4948
    • Kawano, Y.1    Noma, T.2    Yata, J.3
  • 38
    • 0029054278 scopus 로고
    • Single exposure of mice to Borrelia burgdorferi elicits immunoglobulin G antibodies characteristic of secondary immune response without production of interleukin-4 by immune T cells
    • Frey, A. B. and Rao, T. D. 1995. Single exposure of mice to Borrelia burgdorferi elicits immunoglobulin G antibodies characteristic of secondary immune response without production of interleukin-4 by immune T cells. Infect. Immun. 63:2596.
    • (1995) Infect. Immun. , vol.63 , pp. 2596
    • Frey, A.B.1    Rao, T.D.2
  • 39
    • 0026738661 scopus 로고
    • + T cells in vitro: Characteristics and antigen-presenting cell requirements
    • + T cells in vitro: characteristics and antigen-presenting cell requirements. J. Exp. Med. 176:1431.
    • (1992) J. Exp. Med. , vol.176 , pp. 1431
    • Croft, M.1    Duncan, D.D.2    Swain, S.L.3
  • 40
    • 0026648380 scopus 로고
    • Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system
    • Hsieh, C. S., Heimberger, A. B., Gold, J. S., O'Garra, A. and Murphy, K. M. 1992. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc. Natl Acad. Sci. USA 89:6065.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 6065
    • Hsieh, C.S.1    Heimberger, A.B.2    Gold, J.S.3    O'Garra, A.4    Murphy, K.M.5
  • 41
    • 0025082313 scopus 로고
    • Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
    • Le Gros, G., Ben-Sasson, S. Z., Seder, R., Finkelman, F. D. and Paul, W. E. 1990. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J. Exp. Med. 172:921.
    • (1990) J. Exp. Med. , vol.172 , pp. 921
    • Le Gros, G.1    Ben-Sasson, S.Z.2    Seder, R.3    Finkelman, F.D.4    Paul, W.E.5
  • 42
    • 0029942460 scopus 로고    scopus 로고
    • Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro
    • Taub, D. D., Turcovski-Corrales, S. M., Key, M. L., Longo, D. L. and Murphy, W. J. 1996. Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro. J. Immunol. 156:2095.
    • (1996) J. Immunol. , vol.156 , pp. 2095
    • Taub, D.D.1    Turcovski-Corrales, S.M.2    Key, M.L.3    Longo, D.L.4    Murphy, W.J.5
  • 43
    • 0025073294 scopus 로고
    • Direct cytotoxicity of polymorphonuclear leukocyte granule proteins to human lung-derived cells and endothelial cells
    • Okrent, D. G., Lichtenstein, A. K. and Ganz, T. 1990. Direct cytotoxicity of polymorphonuclear leukocyte granule proteins to human lung-derived cells and endothelial cells. Am. Rev. Respir. Dis. 141:179.
    • (1990) Am. Rev. Respir. Dis. , vol.141 , pp. 179
    • Okrent, D.G.1    Lichtenstein, A.K.2    Ganz, T.3
  • 44
    • 0022886732 scopus 로고
    • In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes
    • Lichtenstein, A., Ganz, T., Selsted, M. E. and Lehrer, R. I. 1986. In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes. Blood 68:1407.
    • (1986) Blood , vol.68 , pp. 1407
    • Lichtenstein, A.1    Ganz, T.2    Selsted, M.E.3    Lehrer, R.I.4
  • 45
    • 0023905142 scopus 로고
    • Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity
    • Lichtenstein, A. K., Ganz, T., Nguyen, T. M., Selsted, M. E. and Lehrer, R. I. 1988. Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity. J. Immunol. 140:2686.
    • (1988) J. Immunol. , vol.140 , pp. 2686
    • Lichtenstein, A.K.1    Ganz, T.2    Nguyen, T.M.3    Selsted, M.E.4    Lehrer, R.I.5
  • 46
    • 0032005344 scopus 로고    scopus 로고
    • Antimicrobial peptides of vertebrates
    • Ganz, T. and Lehrer, R. I. 1998. Antimicrobial peptides of vertebrates. Curr. Opin. Immunol. 10:41.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 41
    • Ganz, T.1    Lehrer, R.I.2
  • 48
    • 0026712324 scopus 로고
    • Cryptdins: Antimicrobial defensins of the murine small intestine
    • Eisenhauer, P. B., Harwig, S. S. and Lehrer, R. I. 1992. Cryptdins: antimicrobial defensins of the murine small intestine. Infect. Immun. 60:3556.
    • (1992) Infect. Immun. , vol.60 , pp. 3556
    • Eisenhauer, P.B.1    Harwig, S.S.2    Lehrer, R.I.3


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