Chromosomal imbalances in the colorectal carcinomas with microsatellite instability

American Journal of Pathology

Volumn 163, Issue 4, 2003, Pages 1429-1436

  Li, Long Shan ^a   Kim, Nam Gyun ^a   Kim, Se Hoon ^a   Park, Chanil ^a   Kim, Hyunki ^a   Kang, Hyun Ju ^a   Koh, Kwi Hye ^a   Kim, Soo Nyung ^b   Kim, Won Ho ^a   Kim, Nam Kyu ^a   Kim, Hoguen ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Konkuk University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ADULT; ARTICLE; BRAD50 GENE; CHROMOSOME 13Q; CHROMOSOME 15Q; CHROMOSOME 17P; CHROMOSOME 18Q; CHROMOSOME 20Q; CHROMOSOME 4Q; CHROMOSOME 8Q; CHROMOSOME 9Q; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; COLORECTAL CARCINOMA; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA REPAIR; FEMALE; FLJ11383 GENE; GENE; GENE MUTATION; GENE TARGETING; GENETIC STABILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MOLECULAR GENETICS; PRIORITY JOURNAL;

EID: 0141425677     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63500-6     Document Type: Article

References (39)

1. Lengauer C, Kinzler KW, Vogelstein B: Genetic instabilities in human cancers. Nature 1998, 396:643-649
2. Kinzler KW, Vogelstein B: Lessons from hereditary colorectal cancer. Cell 1996, 87:159-170
3. Lengauer C, Kinzler KW, Vogelstein B: Genetic instability in colorectal cancers. Nature 1997, 386:623-627
4. Miyazaki M, Furuya T, Shiraki A, Sato T, Oga A, Sasaki K: The relationship of DNA ploidy to chromosomal instability in primary human colorectal cancers. Cancer Res 1999, 59:5283-5285
5. Kolodner RD, Putnam CD, Myung K: Maintenance of genome stability in Saccharomyces cerevisiae. Science 2002, 297:552-557
6. Chen C, Kolodner RD: Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat Genet 1999, 23:81-85
7. Myung K, Datta A, Kolodner RD: Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell 2001, 104:397-408
8. Myung K, Chen C, Kolodner RD: Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae. Nature 2001, 411:1073-1076
9. Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M: Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993, 363:558-561
10. Thibodeau SN, Bren G, Schaid D: Microsatellite instability in cancer of the proximal colon. Science 1993, 260:816-819
11. Curtis LJ, Georgiades IB, White S, Bird CC, Harrison DJ, Wyllie AH: Specific patterns of chromosomal abnormalities are associated with RER status in sporadic colorectal cancer. J Pathol 2000, 192:440-445
12. Eshleman JR, Casey G, Kochera ME, Sedwick WD, Swinler SE, Veigl ML, Willson JK, Schwartz S, Markowitz SD: Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53. Oncogene 1998, 17:719-725
13. Abdel-Rahman WM, Katsura K, Rens W, Gorman PA, Sheer D, Bicknell D, Bodmer WF, Arends MJ, Wyllie AH, Edwards PA: Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement. Proc Natl Acad Sci USA 2001, 98:2538-2543
14. Kim NG, Choi YR, Baek MJ, Kim YH, Kang H, Kim NK, Min JS, Kim H: Frameshift mutations at coding mononucleotide repeats of the hRAD50 gene in gastrointestinal carcinomas with microsatellite instability. Cancer Res 2001, 61:36-38
15. Kim NG, Rhee H, Li LS, Kim H, Lee JS, Kim JH, Kim NK, Kim H: Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability. Oncogene 2002, 21:5081-5087
16. Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez-Bigas MA, Fodde R, Ranzani GN, Srivastava S: A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998, 58:5248-5257
17. Kim H, Kim YH, Kim SE, Kim NG, Noh SH, Kim H: Concerted promoter hypermethylation of hMLH1, p16INK4A, and E-cadherin in gastric carcinomas with microsatellite instability. J Pathol 2003, 200:23-31
18. Baek MJ, Kang H, Kim SE, Park JH, Lee JS, Paik YK, Kim H: Expression of hMLH1 is inactivated in the gastric adenomas with enhanced microsatellite instability. Br J Cancer 2001, 85:1147-1152
19. Chung KY, Kim NG, Li LS, Kim H, Kim H, Nam CM, Kim H, Shin DH: Clinicopathologic characteristics related to the high variability of coding mononucleotide repeat sequences in tumors with high-microsatellite instability. Oncol Rep 2003, 10:439-444
20. Hempen PM, Zhang L, Bansal RK, Iacobuzio-Donahue CA, Murphy KM, Maitra A, Vogelstein B, Whitehead RH, Markowitz SD, Willson JK, Yeo CJ, Hruban RH, Kern SE: Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. Cancer Res 2003, 63:994-999
21. Duval A, Rolland S, Compoint A, Tubacher E, Iacopetta B, Thomas G, Hamelin R: Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers. Hum Mol Genet 2001, 10:513-518
22. Thorstensen L, Diep CB, Meling GI, Aagesen TH, Ahrens CH, Rognum TO, Lothe RA: WNT1 inducible signaling pathway protein 3, WISP-3, a novel target gene in colorectal carcinomas with microsatellite instability. Gastroenterology 2001, 121:1275-1280
23. Mertens F, Johansson B, Hoglund M, Mitelman F: Chromosomal imbalance maps of malignant solid tumors: a cytogenetic survey of 3185 neoplasms. Cancer Res 1997, 57:2765-2780
24. Nowell PC: Genetic alterations in leukemias and lymphomas: impressive progress and continuing complexity. Cancer Genet Cytogenet 1997, 94:13-19
25. Kane MF, Loda M, Gaida GM, Lipman J, Mishra R, Goldman H, Jessup JM, Kolodner R: Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 1997, 57:808-811
26. Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JP, Markowitz S, Willson JK, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB: Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 1998, 95:6870-6875
27. Schleger J, Stumm G, Scherthan H, Bocker T, Zirngibl H, Ruschoff J, Hofstadter F: Comparative genomic in situ hybridization of colon carcinomas with replication error. Cancer Res 1995, 55:6002-6005
28. Willenbucher RF, Aust DE, Chang CG, Zelman SJ, Ferrell LD, Moore DH, Waldman FM: Genomic instability is an early event during the progression pathway of ulcerative-colitis-related neoplasia. Am J Pathol 1999, 154:1825-1830
29. Goel A, Arnold CN, Niedzwiecki D, Chang DK, Ricciardiello L, Carethers JM, Dowell JM, Wasserman L, Compton C, Mayer RJ, Bertagnolli MM, Boland CR: Characterization of sporadic colon cancer by patterns of genomic instability. Cancer Res 2003, 63:1608-1614
30. Loeb LA: Microsatellite instability: marker of a mutator phenotype in cancer. Cancer Res 1994, 54:5059-5063
31. Fujiwara T, Stolker JM, Watanabe T, Rashid A, Longo P, Eshleman JR, Booker S, Lynch HT, Jass JR, Green JS, Kim H, Jen J, Vogelstein B, Hamilton SR: Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences. Am J Pathol 1998, 153:1063-1078
32. Malkhosyan S, Rampino N, Yamamoto H, Perucho M: Frameshift mutator mutations. Nature 1996, 382:499-500
33. Mori Y, Yin J, Rashid A, Leggett BA, Young J, Simms L, Kuehl PM, Langenberg P, Meltzer SJ, Stine OC: Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability. Cancer Res 2001, 61:6046-6049
34. Duval A, Hamelin R: Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability. Cancer Res 2002, 62:2447-2454
35. Kim JJ, Baek MJ, Kim L, Kim NG, Lee YC, Song SY, Noh SH, Kim H: Accumulated frameshift mutations at coding nucleotide repeats during the progression of gastric carcinoma with microsatellite instability. Lab Invest 1999, 79:1113-1120
36. Schar P: Spontaneous DNA damage, genome instability, and cancer-when DNA replication escapes control. Cell 2001, 104:329-332
37. Woerner SM, Gebert J, Yuan YP, Sutter C, Ridder R, Bork P, von Knebel Doeberitz M: Systematic identification of genes with coding microsatellites mutated in DNA mismatch repair-deficient cancer cells. Int J Cancer 2001, 93:12-19
38. Chen C, Kolodner RD: Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat Genet 1999, 23:81-85
39. Giannini G, Ristori E, Cerignoli F, Rinaldi C, Zani M, Viel A, Ottini L, Crescenzi M, Martinotti S, Bignami M, Frati L, Screpanti I, Gulino A: Human MRE11 is inactivated in mismatch repair-deficient cancers. EMBO Rep 2002, 3:248-254