Anti-inflammatory and analgesic effects of a novel pyrazole derivative, FR140423

European Journal of Pharmacology

Volumn 365, Issue 2-3, 1999, Pages 259-266

  Ochi, Takehiro ^a   Jobo Magari, Katsue ^a   Yonezawa, Atsuo ^a   Matsumori, Kanae ^a   Fujii, Takashi ^a  

^a Med Chemistry Research Laboratories   (Japan)

Author keywords

Analgesia; Anti inflammation; Cyclooxygenase 2; FR140423; Opioid; Rat

Indexed keywords

3 (DIFLUOROMETHYL) 1 (4 METHOXYPHENYL) 5 [4 (METHYLSULFINYL)PHENYL]PYRAZOLE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; INDOMETACIN; MORPHINE; NALOXONE; NONSTEROID ANTIINFLAMMATORY AGENT; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FUNGI; INDOMETHACIN; ISOENZYMES; MALE; MEMBRANE PROTEINS; MOLECULAR STRUCTURE; NALOXONE; PAIN MEASUREMENT; PEPTIC ULCER; PEROXIDASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; PYRAZOLONES; RATS; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SULFOXIDES;

EID: 0032910180     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00868-1     Document Type: Article

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