Guarding the genome: Electrostatic repulsion of water by DNA suppresses a potent nuclease activity of topoisomerase IB

Molecular Cell

Volumn 12, Issue 1, 2003, Pages 199-208

  Tian, Ligeng ^a   Claeboe, Christopher D ^b   Hecht, Sidney M ^b   Shuman, Stewart ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA TOPOISOMERASE; ENDONUCLEASE; ESTER DERIVATIVE; METHYLPHOSPHONIC ACID; WATER;

ACHILLES TENDON; ARTICLE; COVALENT BOND; ELECTRICITY; GENOME ANALYSIS; HYDROLYSIS; LINKAGE ANALYSIS; NONHUMAN; PROTEIN DNA INTERACTION; PROTEIN FUNCTION;

EID: 0043127392     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(03)00263-6     Document Type: Article

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