Effects of intraocular injection of a low concentration of zinc on the rat retina

Neuropharmacology

Volumn 45, Issue 5, 2003, Pages 637-648

  Nakamichi, N ^a   Chidlow, G ^b   Osborne, N N ^b  

^a KANAZAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Glial cells; Ischemia; Neuroprotection; NMDA; Retinal ganglion cells; Zinc

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BIOLOGICAL MARKER; CILIARY NEUROTROPHIC FACTOR; CYCLOOXYGENASE 2; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID; NITRIC OXIDE SYNTHASE; ZINC;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; ELECTRORETINOGRAM; ENZYME ACTIVITY; GLIA CELL; ISCHEMIA; LOW DRUG DOSE; NEUROFILAMENT; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REPERFUSION INJURY; RETINA; STATISTICAL SIGNIFICANCE; UPREGULATION; WAVEFORM;

EID: 0043073212     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(03)00206-5     Document Type: Article

References (60)

1. Acarin L., Peluffo H., Gonzalez B., Castellano B. Expression of inducible nitric oxide synthase and cyclooxygenase-2 after excitotoxic damage to the immature rat brain. Journal of Neuroscience Research. 68:2002;745-754.
2. Adachi K., Kashii S., Masai H., Ueda M., Morizane C., Kaneda K., Kume T., Akaike A., Honda Y. Mechanism of the pathogenesis of glutamate neurotoxicity in retinal ischemia. Graefes Archive for Clinical and Experimental Ophthalmology. 236:1998;766-774.
3. Akagi T., Kaneda M., Ishii K., Hashikawa T. Differential subcellular localization of zinc in the rat retina. Journal of Histochemistry and Cytochemistry. 49:2001;87-96.
4. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Archives of Ophthalmology. 119:2001;1417-1436.
5. 2+ from brain tissue during activity. Nature. 308:1984;734-736.
6. Beatty S., Koh H., Phil M., Henson D., Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Survey of Ophthalmology. 45:2000;115-134.
7. Block F., Schwarz M. The b-wave of the electroretinogram as an index of retinal ischemia. General Pharmacology. 30:1998;281-287.
8. Bolanos J.P., Almeida A. Roles of nitric oxide in brain hypoxia-ischemia. Biochimica et Biophysica Acta. 1411:1999;415-436.
9. Cai J., Nelson K.C., Wu M., Sternberg P. Jr., Jones D.P. Oxidative damage and protection of the RPE. Progress in Retinal and Eye Research. 19:2000;205-221.
10. Candelario Jalil E., Alvarez D., Gonzalez Falcon A., Garcia Cabrera M., Martinez Sanchez G., Merino N., Giuliani A., Leon O.S. Neuroprotective efficacy of nimesulide against hippocampal neuronal damage following transient forebrain ischemia. European Journal of Pharmacology. 453:2002;189-195.
11. Cayouette M., Gravel C. Adenovirus-mediated gene transfer of ciliary neurotrophic factor can prevent photoreceptor degeneration in the retinal degeneration (rd) mouse. Human Gene Therapy. 8:1997;423-430.
12. Chidlow G., Osborne N.N. Rat retinal ganglion cell loss caused by kainate, NMDA and ischemia correlates with a reduction in mRNA and protein of Thy-1 and neurofilament light. Brain Research. 963:2003;298-306.
13. Chidlow G., Schmidt K.G., Wood J.P., Melena J., Osborne N.N. Alpha-lipoic acid protects the retina against ischemia-reperfusion. Neuropharmacology. 43:2002;1015-1025.
14. Choi D.W., Koh J.Y. Zinc and brain injury. Annual Review of Neuroscience. 21:1998;347-375.
15. Chun M.H., Ju W.K., Kim K.Y., Lee M.Y., Hofmann H.D., Kirsch M., Oh S.J. Upregulation of ciliary neurotrophic factor in reactive Muller cells in the rat retina following optic nerve transection. Brain Research. 868:2000;358-362.
16. Cioffi G.A. Three common assumptions about ocular blood flow and glaucoma. Survey of Ophthalmology. 45:(Suppl. 3):2001;S325-S331.
17. Cuajungco M.P., Lees G.J. Zinc metabolism in the brain: relevance to human neurodegenerative disorders. Neurobiology of Disease. 4:1997;137-169.
18. Faktorovich E.G., Steinberg R.H., Yasumura D., Matthes M.T., LaVail M.M. Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor. Nature. 347:1990;83-86.
19. Faktorovich E.G., Steinberg R.H., Yasumura D., Matthes M.T., LaVail M.M. Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat. Journal of Neuroscience. 12:1992;3554-3567.
20. Geyer O., Almog J., Lupu Meiri M., Lazar M., Oron Y. Nitric oxide synthase inhibitors protect rat retina against ischemic injury. FEBS Letters. 374:1995;399-402.
21. Grahn B.H., Paterson P.G., Gottschall Pass K.T., Zhang Z. Zinc and the eye. Journal of the American College of Nutrition. 20:2001;106-118.
22. Grimm C., Wenzel A., Williams T., Rol P., Hafezi F., Reme C. Rhodopsin-mediated blue-light damage to the rat retina: effect of photoreversal of bleaching. Investigative Ophthalmology and Visual Science. 42:2001;497-505.
23. Han Y., Wu S.M. Modulation of glycine receptors in retinal ganglion cells by zinc. Proceedings of the National Academy of Sciences of the United States of America. 96:1999;3234-3238.
24. Hangai M., Yoshimura N., Hiroi K., Mandai M., Honda Y. Inducible nitric oxide synthase in retinal ischemia-reperfusion injury. Experimental Eye Research. 63:1996;501-509.
25. 2+: an endogenous modulator of ligand- and voltage-gated ion channels. Neuropharmacology. 33:1994;935-952.
26. Honjo M., Tanihara H., Kido N., Inatani M., Okazaki K., Honda Y. Expression of ciliary neurotrophic factor activated by retinal Muller cells in eyes with NMDA- and kainic acid-induced neuronal death. Investigative Ophthalmology and Visual Science. 41:2000;552-560.
27. Iadecola C. Bright and dark sides of nitric oxide in ischemic brain injury. Trends in Neuroscience. 20:1997;132-139.
28. Ju W.K., Lee M.Y., Hofmann H.D., Kirsch M., Chun M.H. Expression of CNTF in Muller cells of the rat retina after pressure-induced ischemia. Neuroreport. 10:1999;419-422.
29. Kikuchi M., Kashii S., Honda Y., Ujihara H., Sasa M., Tamura Y., Akaike A. Protective action of zinc against glutamate neurotoxicity in cultured retinal neurons. Investigative Ophthalmology and Visual Science. 36:1995;2048-2053.
30. Kim S.Y., Kwak J.S., Shin J.P., Lee S.H. The protection of the retina from ischemic injury by the free radical scavenger EGb 761 and zinc in the cat retina. Ophthalmologica. 212:1998;268-274.
31. Koh J.Y., Choi D.W. Zinc toxicity on cultured cortical neurons: involvement of N-methyl-D-aspartate receptors. Neuroscience. 60:1994;1049-1057.
32. Lobner D., Canzoniero L.M., Manzerra P., Gottron F., Ying H., Knudson M., Tian M., Dugan L.L., Kerchner G.A., Sheline C.T., Korsmeyer S.J., Choi D.W. Zinc-induced neuronal death in cortical neurons. Cellular and Molecular Biology. 46:2000;797-806.
33. Louzada P. Jr., Dias J.J., Santos W.F., Lachat J.J., Bradford H.F., Coutinho Netto J. Glutamate release in experimental ischemia of the retina: an approach using microdialysis. Journal of Neurochemistry. 59:1992;358-363.
34. Lynch D.R., Guttmann R.P. NMDA receptor pharmacology: perspectives from molecular biology. Current Drug Targets. 2:2001;215-231.
35. Matsushita K., Kitagawa K., Matsuyama T., Ohtsuki T., Taguchi A., Mandai K., Mabuchi T., Yagita Y., Yanagihara T., Matsumoto M. Effect of systemic zinc administration on delayed neuronal death in the gerbil hippocampus. Brain Research. 743:1996;362-365.
36. Minghetti L., Levi G. Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide. Progress in Neurobiology. 54:1998;99-125.
37. Morrison J.C., Moore C.G., Deppmeier L.M., Gold B.G., Meshul C.K., Johnson E.C. A rat model of chronic pressure-induced optic nerve damage. Experimental Eye Research. 64:1997;85-96.
38. Nash M.S., Osborne N.N. Assessment of Thy-1 mRNA levels as an index of retinal ganglion cell damage. Investigative Ophthalmology and Visual Science. 40:1999;1293-1298.
39. Neufeld A.H., Kawai S., Das S., Vora S., Gachie E., Connor J.R., Manning P.T. Loss of retinal ganglion cells following retinal ischemia: the role of inducible nitric oxide synthase. Experimental Eye Research. 75:2002;521-528.
40. Osborne N.N., Ugarte M., Chao M., Chidlow G., Bae J.H., Wood J.P., Nash M.S. Neuroprotection in relation to retinal ischemia and relevance to glaucoma. Survey of Ophthalmology. 43:(Suppl. 1):1999;S102-S128.
41. Osborne N.N., Wood J.P., Chidlow G., Bae J.H., Melena J., Nash M.S. Ganglion cell death in glaucoma: what do we really know? British Journal of Ophthalmology. 83:1999;980-986.
42. Osborne N.N., Melena J., Chidlow G., Wood J.P. A hypothesis to explain ganglion cell death caused by vascular insults at the optic nerve head: possible implication for the treatment of glaucoma. British Journal of Ophthalmology. 85:2001;1252-1259.
43. Qian H., Li L., Chappell R.L., Ripps H. GABA receptors of bipolar cells from the skate retina: actions of zinc on GABA-mediated membrane currents. Journal of Neurophysiology. 78:1997;2402-2412.
44. Siesjo B.K. Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment. Journal of Neurosurgery. 77:1992;337-354.
45. Siesjo B.K. A new perspective on ischemic brain damage? Progress in Brain Research. 96:1993;1-9.
46. Smart T.G., Xie X., Krishek B.J. Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc. Progress in Neurobiology. 42:1994;341-393.
47. Suh S.W., Chen J.W., Motamedi M., Bell B., Listiak K., Pons N.F., Danscher G., Frederickson C.J. Evidence that synaptically-released zinc contributes to neuronal injury after traumatic brain injury. Brain Research. 852:2000;268-273.
48. Ugarte M., Osborne N.N. The localization of endogenous zinc and the in vitro effect of exogenous zinc on the GABA immunoreactivity and formation of reactive oxygen species in the retina. General Pharmacology. 30:1998;297-303.
49. Ugarte M., Osborne N.N. The localization of free zinc varies in rat photoreceptors during light and dark adaptation. Experimental Eye Research. 69:1999;459-461.
50. Ugarte M., Osborne N.N. Zinc in the retina. Progress in Neurobiology. 64:2001;219-249.
51. Unoki K., LaVail M.M. Protection of the rat retina from ischemic injury by brain-derived neurotrophic factor, ciliary neurotrophic factor, and basic fibroblast growth factor. Investigative Ophthalmology and Visual Science. 35:1994;907-915.
52. Wen R., Song Y., Cheng T., Matthes M.T., Yasumura D., LaVail M.M., Steinberg R.H. Injury-induced upregulation of bFGF and CNTF mRNAS in the rat retina. Journal of Neuroscience. 15:1995;7377-7385.
53. Wen R., Cheng T., Song Y., Matthes M.T., Yasumura D., LaVail M.M., Steinberg R.H. Continuous exposure to bright light upregulates bFGF and CNTF expression in the rat retina. Current Eye Research. 17:1998;494-500.
54. Wood J.P., Osborne N.N. The influence of zinc on caspase-3 and DNA breakdown in cultured human retinal pigment epithelial cells. Archives of Ophthalmology. 119:2001;81-88.
55. Wu S.M., Qiao X., Noebels J.L., Yang X.L. Localization and modulatory actions of zinc in vertebrate retina. Vision Research. 33:1993;2611-2616.
56. Yang X.L., Li P., Lu T., Shen Y., Han M.H. Physiological and pharmacological characterization of glutamate and GABA receptors on carp retinal neurons. Progress in Brain Research. 131:2001;277-293.
57. Yip H.K., So K.F. Axonal regeneration of retinal ganglion cells: effect of trophic factors. Progress in Retinal and Eye Research. 19:2000;559-575.
58. Zago M.P., Oteiza P.I. The antioxidant properties of zinc: interactions with iron and antioxidants. Free Radical Biology and Medicine. 31:2001;266-274.
59. Zhang D.Q., Ribelayga C., Mangel S.C., McMahon D.G. Suppression by zinc of AMPA receptor-mediated synaptic transmission in the retina. Journal of Neurophysiology. 88:2002;1245-1251.
60. Zhao Y.J., Yang G.Y., Domino E.F. Zinc protoporphyrin, zinc ion, and protoporphyrin reduce focal cerebral ischemia. Stroke. 27:1996;2299-2303.