Inconspicuous insertion 22;12 in myxoid/round cell liposarcoma accompanied by the secondary structural abnormality der(16)t(1;16)

Journal of Molecular Diagnostics

Volumn 5, Issue 3, 2003, Pages 191-194

  Birch, Nathan C ^a   Antonescu, Cristina R ^b   Nelson, Marilu ^a   Sarran, Lisa ^a   Neff, James R ^a   Seemayer, Thomas ^a   Bridge, Julia A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN;

ADULT; ARTICLE; CASE REPORT; CHROMOSOME 12; CHROMOSOME 22; CHROMOSOME INSERTION; CHROMOSOME TRANSLOCATION 1; CHROMOSOME TRANSLOCATION 12; CHROMOSOME TRANSLOCATION 16; CHROMOSOME VARIANT; EWING SARCOMA; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; KARYOTYPE; MALE; MOLECULAR GENETICS; MYXOSARCOMA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOMA; STRUCTURAL CHROMOSOME ABERRATION;

INSERTION SEQUENCES;

EID: 0043066830     PISSN: 15251578     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1525-1578(10)60472-2     Document Type: Article

References (20)

1. Bridge JA, Roberts CA, Degenhardt J, Walker C, Lackner R, Linder J: Low-level chromosome 12 amplification in a primary lipoma of the lung: evidence for a pathogenetic relationship with common adipose tissue tumors. Arch Pathol Lab Med 1998, 122:187-190
2. Bridge JA, Fidler ME, Neff JR, Degenhardt J, Wang M, Walker C, Dorfman HD, Baker KS, Seemayer TA: Adamantinoma-like Ewing's sarcoma: genomic confirmation, phenotypic drift. Am J Surg Pathol 1999, 23:159-165
3. Desmaze C, Zucman J, Delattre O, Melot T, Thomas G, Aurias A: Interphase molecular cytogenetics of Ewing's sarcoma and peripheral neuroepithelioma t(11;22) with flanking and overlapping cosmid probes. Cancer Genet Cytogenet 1994, 74:13-18
4. Antonescu CR, Tschernyavsky SJ, Decuseara R, Leung DH, Woodruff JM, Brennan MF, Bridge JA, Neff JR, Goldblum JR, Ladanyi M: Prognostic impact of P53 status, TLS-CHOP fusion transcript structure, and histological grade in myxoid liposarcoma: a molecular and clinicopathologic study of 82 cases. Clin Cancer Res 2001, 7:3977-3987
5. Weiss SW, Goldblum JR: Soft Tissue Tumors. St. Louis, Mosby, Inc., 2001, pp 670-687
6. Sreekantaiah C, Ladanyi M, Rodriguez E, Chaganti RS: Chromosomal aberrations in soft tissue tumors: relevance to diagnosis, classification, and molecular mechanisms. Am J Pathol 1994, 144:1121-1134
7. Tallini G, Akerman M, Dal Cin P, De Wever I, Fletcher CD, Mandahl N, Mertens F, Mitelman F, Rosai J, Rydholm A, Sciot R, Van den Berghe H, Van den Ven W, Vanni R, Willen H: Combined morphologic and karyotypic study of 28 myxoid liposarcomas: implications for a revised morphologic typing: a report from the CHAMP Group. Am J Surg Pathol 1996, 20:1047-1055
8. Fletcher CD, Akerman M, Dal Cin P, de Wever I, Mandahl N, Mertens F, Mitelman F, Rosai J, Rydholm A, Sciot R, Tallini G, van den Berghe H, van de Ven W, Vanni R, Willen H: Correlation between clinicopathological features and karyotype in lipomatous tumors: a report of 178 cases from the Chromosomes and Morphology (CHAMP) Collaborative Study Group. Am J Pathol 1996, 148:623-630
9. Hattinger CM, Rumpler S, Ambros IM, Strehl S, Lion T, Zoubek A, Gadner H, Ambros PF: Demonstration of the translocation der(16)t(1;16)(q12;q11.2) in interphase nuclei of Ewing tumors. Genes Chromosomes Cancer 1996, 17:141-150
10. Day SJ, Nelson M, Rosenthal H, Vergara GG, Bridge JA: Der(16)t(1; 16)(q21;q13) as a secondary structural aberration in yet a third sarcoma, extraskeletal myxoid chondrosarcoma. Genes Chromosomes Cancer 1997, 20:425-427
11. Mitelman Database of Chromosome Aberrations in Cancer. http://cgap.nci.nih.gov/Chromosomes/Mitelman, 2003
12. Tarkkanen M, Karaharju E, Bohling T, Szymanska J, Helio H, Kivioja A, Elomaa I, Knuutila S: Chromosome study of 249 patients examined for a bone tumor. Clin Orthop 1993:117-128
13. Stark B, Mor C, Jeison M, Gobuzov R, Cohen IJ, Goshen Y, Stein J, Fisher S, Ash S, Yaniv I, Zaizov R: Additional chromosome 1q aberrations and der(16)t(1;16), correlation to the phenotypic expression and clinical behavior of the Ewing family of tumors. J Neurooncol 1997, 31:3-8
14. Hattinger CM, Rumpler S, Strehl S, Ambros IM, Zoubek A, Potschger U, Gadner H, Ambros PF: Prognostic impact of deletions at 1p36 and numerical aberrations in Ewing tumors. Genes Chromosomes Cancer 1999, 24:243-254
15. Sandberg AA, Bridge JA: Updates on cytogenetics and molecular genetics of bone and soft tissue tumors: Ewing sarcoma and peripheral primitive neuroectodermal tumors. Cancer Genet Cytogenet 2000, 123:1-26
16. Gibas Z, Miettinen M, Limon J, Nedoszytko B, Mrozek K, Roszkiewicz A, Rys J, Niezabitowski A, Debiec-Rychter M: Cytogenetic and immunohistochemical profile of myxoid liposarcoma. Am J Clin Pathol 1995, 103:20-26
17. Antonescu CR, Elahi A, Healey JH, Brennan MF, Lui MY, Lewis J, Jhanwar SC, Woodruff JM, Ladanyi M: Monoclonality of multifocal myxoid liposarcoma: confirmation by analysis of TLS-CHOP or EWSCHOP rearrangements. Clin Cancer Res 2000, 6:2788-2793
18. Panagopoulos I, Hoglund M, Mertens F, Mandahl N, Mitelman F, Aman P: Fusion of the EWS and CHOP genes in myxoid liposarcoma. Oncogene 1996, 12:489-494
19. Panagopoulos I, Lassen C, Isaksson M, Mitelman F, Mandahl N, Aman P: Characteristic sequence motifs at the breakpoints of the hybrid genes FUS/CHOP, EWS/CHOP, and FUS/ERG in myxoid liposarcoma and acute myeloid leukemia. Oncogene 1997, 15:1357-1362
20. Dal Cin P, Sciot R, Panagopoulos I, Aman P, Samson I, Mandahl N, Mitelman F, Van den Berghe H, Fletcher CD: Additional evidence of a variant translocation t(12;22) with EWS/CHOP fusion in myxoid liposarcoma: clinicopathological features. J Pathol 1997, 182:437-441