Correlation between clinicopathological features and karyotype in lipomatous tumors: A report of 178 cases from the Chromosomes and Morphology (CHAMP) Collaborative Study Group

American Journal of Pathology

Volumn 148, Issue 2, 1996, Pages 623-630

  Fletcher, Christopher D M ^a,g   Akerman, Mans ^b   Dal Cin, Paola ^c   De Wever, Ivo ^c   Mandahl, Nils ^b   Mertens, Fredrik ^b   Mitelman, Felix ^b   Rosai, Juan ^d   Rydholm, Anders ^b   Sciot, Raf ^c   Tallini, Giovanni ^e   Van Berghe, Herman Den ^c   Van Ven, Wim De ^c   Vanni, Roberta ^c,f   Willen, Helena ^b  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF CAGLIARI   (Italy)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION; CLINICAL FEATURE; CLINICAL TRIAL; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DOUBLE BLIND PROCEDURE; HUMAN; HUMAN CELL; HUMAN TISSUE; KARYOTYPE; LIPOMA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RELIABILITY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANGIOLIPOMA; CHILD; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; FEMALE; HUMANS; KARYOTYPING; LIPOMA; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SOFT TISSUE NEOPLASMS;

EID: 0042154054     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Heim S, Mitelman F Cancer Cytogenetics, ed 2 New York, Wiley-Liss, 1995
2. Sandberg AA, Bridge JA: The Cytogenetics of Bone and Soft Tissue Tumors Austin, TX, RG Landes Co, 1994
3. Mitelman F. Catalog of Chromosome Aberrations in Cancer, ed 5. New York. Wiley-Liss, 1994
4. Sreekantaiah C, Ladanyi M, Rodriguez E, Chaganti RSK. Chromosomal aberrations in soft tissue tumors relevance to diagnosis, classification, and molecular mechanisms. Am J Pathol 1994, 144 1121-1134
5. Sreekantaiah C, Sandberg AA. Clustering of aberrations to specific chromosome regions in benign neoplasms Int J Cancer 1991, 48:194-198
6. Fletcher JA, Kozakewich HP, Hoffer FA, Lage JM, Weidner N, Tepper R, Pinkus GC, Morton CC, Corson JM: Diagnostic relevance of clonal cytogenetic aberrations in malignant soft-tissue tumors N Engl J Med 1991, 324:436-442
7. Molenaar WM, DeJong B, Buist J, Idenburg VJS, Seruca R, Vos AM, Hoekstra MJ: Chromosomal analysts and the classification of soft tissue sarcomas. Lab Invest 1989, 60.266-274
8. Scrable H, Witte D, Shimada H, Seemayer T, Wang-Wuu S, Sonkup S, Koufos A, Houghton P, Lampkin B, Cavenee W Molecular differential pathology of rhabdomyosarcoma. Genes Chromosomes & Cancer 1989, 1:23-25
9. Downing JR, Khandekar A, Shurtleff SA, Head DR, Parham DM, Webber BL, Pappo AS, Hulshof MA, Conn WP, Shapiro DN: Multiplex RT-PCR assay for the differential diagnosis of alveolar rhabdomyosarcoma and Ewing's sarcoma. Am J Pathol 1995, 146:626-634
10. Mandahl N, Heim S, Johansson B, Bennet K, Mertens F, Olsson G, Rooser B, Rhydholm A, Willen H, Mitelman F: Lipomas have characteristic structural chromosomal rearrangements of 12q13-14. Int J Cancer 1987, 39 685-688
11. Sreekantaiah C, Leong SPL, Karokousis CP, McGee DL, Rappaport WD, Villar HV, Neal D, Fleming S, Wankel H, Herrington PN: Cytogenetic profile of 109 lipomas. Cancer Res 1991, 51:422-433
12. Mandahl N, Heim S, Arheden K, Rydholm A, Willen H, Mitelman F. Three major cytogenetic subgroups can be identified among chromosomally abnormal solitary lipomas. Hum Genet 1988, 79:202-208
13. Turc-Carel C, Limon J, Dal Cin P, Rao U, Karakousis C, Sandberg AA. Cytogenetic studies of adipose tissue tumors. II. Recurrent reciprocal translocation t(12,16) (q13;p11) in myxoid liposarcomas. Cancer Genet Cytogenet 1986, 23:291-300
14. Heim S, Mandahl N, Kristoffersson U, Mitelman F, Rooser B, Rydholm A, Willen H: Marker ring chromosome: a new cytogenetic abnormality characterizing lipogenic tumors? Cancer Genet Cytogenet 1987, 24:319-326
15. Heim S, Mandahl N, Rydholm A, Willen H, Mitelman F. Different karyotypic features characterize different clinicopathologic subgroups of benign lipogenic tumors. Int J Cancer 1988, 42 863-867
16. Dal Cin P, Kools P, Sciot R, DeWever I, Van Damme B, Van de Ven W, Van den Berghe H: Cytogenetic and fluorescence in situ hybridization investigation of ring chromosomes characterizing a specific pathologic subgroup of adipose tissue tumors. Cancer Genet Cytogenet 1993, 68.85-90
17. Mandahl N, Hoglund M, Mertens F, Rydholm A, Willen H, Brosjo O, Mitelman F. Cytogenetic aberrations in 188 benign and borderline adipose tissue tumors Genes Chromosomes & Cancer 1994, 9 207-215
18. Enzinger FM, Weiss SW: Soft Tissue Tumors, ed 3 St Louis, CV Mosby, 1995
19. Rosai J: Ackerman's Surgical Pathology, ed 7. St Louis, CV Mosby, 1989 s
20. Fletcher CDM. Soft tissue tumors Diagnostic Histopathology of Tumors. Edited by CDM Fletcher Edinburgh, Churchill Livingstone, 1995 pp 1043-1096
21. Dei Tos AP, Mentzel T, Newman PL, Fletcher CDM: Spindle cell liposarcoma, a hitherto unrecognized vanant of liposarcoma: analysis of six cases. Am J Surg Pathol 1994, 18 913-921
22. Evans HL, Soule EH, Winkelmann RK: Atypical lipoma, atypical intramuscular lipoma and well differentiated retropentoneal liposarcoma a reappraisal of 30 cases formerly classified as well differentiated liposarcoma Cancer 1979, 43.574-584
23. Kindblom L-G, Angervall L, Fassina AS. Atypical lipoma. Acta Pathol Microbiol Scand A 1982, 90.27-36
24. Azumi N, Curtis J, Kempson RL, Hendrickson RM. Atypical and malignant neoplasms showing lipomatous differentiation. Am J Surg Pathol 1989, 11.161-183
25. Evans HL: Liposarcomas and atypical lipomatous tumors a study of 66 cases followed for a minimum of 10 years. Surg Pathol 1988, 1:41-54
26. Weiss SW, Rao VK: Well-differentiated liposarcoma (atypical lipoma) of deep soft tissue of the extremities, retroperitoneum and miscellaneous sites a follow-up study of 92 cases with analysis of the incidence of "dedifferentiation" Am J Surg Pathol 1992, 16.1051-1058
27. Mertens F, Rydholm A, Brosjo O, Willen H, Mitelman F, Mandant N: Hibernomas are characterized by rearrangements of chromosome bands 11q13-21. Int J Cancer 1994, 58.503-505
28. Sreekantaiah C, Karakousis CP, Leong SPL, Sandberg AA. Cytogenetic findings in liposarcoma correlate with histopathologic subtypes. Cancer 1992, 69:2484-2495
29. Mandahl N, Mertens F, Willen H, Rydholm A, Brosjo O, Mitelman F A new Cytogenetic subgroup in lipomas: loss of chromosome 16 material in spindle cell and pleomorphic lipomas. J Cancer Res Clin Oncol 1994, 120 707-711
30. Dal Cin P, Sciot R, De Wever I, Van Damme B, Van den Berghe H: New discriminative chromosomal marker in adipose tissue tumors the chromosome 8q11-q13 region in lipoblastomas. Cancer Genet Cytogenet 1994, 78:232-235
31. Meloni AM, Spanier SS, Bush CH, Stone JF, Sandberg AA. Involvement of 10q22 and 11q13 in hibernoma Cancer Genet Cytogenet 1994, 72 59-64
32. Fletcher CDM: Soft tissue tumours: an update Recent Adv Histopathol 1992, 15:113-139
33. Aman P, Ron D, Mandahl N, Fioretos T, Heim S, Arheden K, Willen M, Rydholm A, Mitelman F: Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12,16)(q13;p11) Genes Chromosomes & Cancer 1992, 5:278-285
34. Knight J, Renwick PJ, Dal Cin P, Van Den Berghe H, Fletcher CDM: Translocation t(12,16)(q13,p11) in myxoid liposarcoma and round cell liposarcoma: molecular and cytogenetic analysis Cancer Res 1995, 55.24-27
35. Mentzel T, Calonje E, Fletcher CDM: Lipoblastoma and lipoblastomatosis: a clinicopathological study of 14 cases. Histopathology 1993, 23.527-533
36. Fletcher JA, Kozakewich HP, Schoenberg ML, Morton CC: Cytogenetic findings in pediatric adipose tumors: consistent rearrangement of chromosome 8 in lipoblastoma. Genes Chromosomes & Cancer 1993, 6:24-29
37. McCormick D, Mentzel T, Beham A, Fletcher CDM: Dedifterentiated liposarcoma: clinicopathologic analysis of 32 cases suggesting a better prognostic subgroup among pleomorphic sarcomas. Am J Surg Pathol 1995, 18:1213-1223
38. Fletcher CDM: Pleomorphic malignant fibrous histiocytoma: fact or fiction? A critical reappraisal based on 159 tumors diagnosed as pleomorphic sarcoma. Am J Surg Pathol 1992, 16:213-228.