Adamantinoma-like Ewing's sarcoma: Genomic confirmation, phenotypic drift

American Journal of Surgical Pathology

Volumn 23, Issue 2, 1999, Pages 159-165

  Bridge, Julia A ^a   Fidler, Mary E ^a   Neff, James R ^a   Degenhardt, Joanne ^a   Wang, Mei ^a   Walker, Craig ^a   Dorfman, Howard D ^b   Baker, K Scott ^a   Seemayer, Thomas A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Adamantinoma; Ewing's sarcoma; EWS FLI1; Karyotype; RT PCR

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; DACTINOMYCIN; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE; VINCRISTINE;

ADOLESCENT; AMELOBLASTOMA; ARTICLE; BONE CANCER; CASE REPORT; CHROMOSOME TRANSLOCATION; CYTOGENETICS; EWING SARCOMA; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENOME; HUMAN; HUMAN CELL; HUMAN TISSUE; KARYOTYPE; MALE; PHENOTYPE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; BONE NEOPLASMS; CYTOGENETICS; DESMOSOMES; DIAGNOSIS, DIFFERENTIAL; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTERMEDIATE FILAMENTS; KERATINS; MALE; NEOPLASMS, GLANDULAR AND EPITHELIAL; ONCOGENE PROTEINS, FUSION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM; SARCOMA, EWING'S; TRANSCRIPTION FACTORS;

EID: 0033014436     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199902000-00004     Document Type: Article

References (30)

1. Aurias A, Rimbaut C, Buffe D, Dubousset J, Mazabraud A. Chromosomal translocations in Ewing's sarcoma. N Engl J Med 1983; 309:496-7.
2. Bridge JA. Soft tissue sarcomas. In: Wolman SR, Sell S. Cytogenetic Markers of Human Disease. Clifton, NJ: Humana Press; 1997:425-59.
3. Bridge JA, DeBoer J, Travis J, et al. Simultaneous interphase cytogenetic analysis and fluorescence immunophenotyping of dedifferentiated chondrosarcoma. Implications for histopathogenesis. Am J Pathol 1994;144:215-20.
4. Bridge JA, Sreekantaiah C, Mouron B, Neff JR, Sandberg AA. Clonal chromosomal abnormalities in desmoid tumors. Implication for histopathogenesis. Cancer 1992;69:430-6.
5. Brinkhuis M, Wijnaendts LCD, van der Linden JC, van Unnik AJM, Voute PA, Baak JPA, Meijer CJLM. Peripheral primitive neuroectodermal tumour and extra-osseous Ewing's sarcoma; a histological, immunohistochemical and DNA flow cytometric study. Virchows Arch 1995;425:611-6.
6. De Alava E, Kawai A, Healey JH, et al. EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma. J Clin Oncol 1998;16:1248-55.
7. de Chadare'vian JP, Vekemans M, Seemayer TA. Reciprocal translocation in small cell sarcomas. N Engl J Med 1984;311: 1702-3.
8. Delattre O, Zucman J, Melot T, et al. The Ewing family of tumors - a subgroup of small-round-cell tumors defined by specific chimeric transcripts. N Engl J Med 1994;331:294-9.
9. Delattre O, Zucman J, Plougastel B, et al. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature 1992;359:162-5.
10. Desmaze C, Zucman J, Delattre O, Melot T, Thomas G, Aurias A. Interphase molecular cytogenetics of Ewing's sarcoma and peripheral neuroepithelioma t(11;22) with flanking and overlapping cosmid probes. Cancer Genet Cytogenet 1994;74:13-8.
11. Enneking WF. A system of staging of musculoskeletal neoplasms. Clin Orthop 1986;204:9-24.
12. Ewing J. Diffuse endothelioma of bone. Proc NY Pathol Soc 1921; 21:17-24.
13. Hazelbag HM, Wessels JW, Mollevangers P, van den Berg E, Molenaar WM, Hogendoorn PCW. Cytogenetic analysis of adamantinoma of long bones: further indications for a common histogenesis with osteofibrous dysplasia. Cancer Genet Cytogenet 1997;97:5-11.
14. Ishida T, Kikuchi F, Oka T, et al. Case report 727. Skel Radiol 1992;21:205-9.
15. Kovar H, Dworzak M, Strehl S, et al. Overexpression of the pseudoautosomal gene MIC2 in Ewing's sarcoma and peripheral primitive neuroectodermal tumor. Oncogene 1990;5:1067-70.
16. Kretschmar CS. Ewing's sarcoma and the "peanut" tumors. N Engl J Med 1994;331:325-7.
17. Ladanyi M. The emerging molecular genetics of sarcoma translocations. Diagn Mol Pathol 1995;4:162-73.
18. Lipper S, Kahn LB. Case report 235. Skel Radiol 1983;10:61-6.
19. Meister P, Konrad E, Hübner G. Malignant tumor of humerus with features of "adamantinoma" and Ewing's sarcoma. Pathol Res Pract 1979;166:112-22.
20. Navarro S, Cavazzano AO, Llombart-Bosh A, Triche TJ. Comparison of Ewing's sarcoma of bone and peripheral neuroepithelioma. An immunocytochemical and ultrastructural analysis of two primitive neuroectodermal neoplasms. Arch Pathol Lab Med 1994; 118:608-15.
21. O'Neil-Smith K, Wittenberg KH, Efird JT, Mankis HJ, Bhan AK, Rosenberg AE. Ewing's sarcoma and peripheral primitive neuroectodermal tumor: a proposal for a standardization classification scheme based on morphologic, immunohistochemical and clinical features. Mod Pathol 1995;8:10A.
22. Sandberg AA, Bridge JA. The cytogenetics of bone and soft tissue tumors. Austin: RG Landes; 1994.
23. Schmidt D, Hermann C, Jürgens H, Harms D. Malignant peripheral neuroectodermal tumor and its necessary distinction from Ewing's sarcoma. A report from the Kiel pediatric tumor registry. Cancer 1991;68:2251-9.
24. Sorensen PHB, Liu XF, Thomas G, et al. Reverse transcriptase PCR amplification of EWS/FLI-1 fusion transcripts as a diagnostic test for peripheral primitive neuroectodermal tumors of childhood. Diagn Mol Pathol 1993;2:147-57.
25. Turc-Carel C, Philip I, Berger MP, Philip T, Lenoir GM. Translocation (11;22) (q24;q12) in Ewing sarcoma cell lines. N Engl J Med 1983;309:497-8.
26. van Haelst UJGM, de Haas van Dorsser AH. A perplexing malignant bone tumor. Highly malignant so-called adamantinoma or non-typical Ewing's sarcoma. Virchows Arch A Path Anat Histol 1975;365:63-74.
27. Whang Peng J, Triche TJ, Knutsen T, Miser J, Dopublass EC, Israel MA. Chromosome translocations in peripheral neuroepithelioma. N Engl J Med 1984;311:584-5.
28. Zoubek A, Dockhorn-Dworniczak B, Delattre O, et al. Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients? J Clin Oncol 1996; 14:1245-51.
29. Zucman J, Delattre O, Desmaze C, et al. Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoints. Genes Chromosom Cancer 1992;5:271-7.
30. Zucman J, Melot T, Desmaze C, et al. Combinational generation of variable fusion proteins in the Ewing family of tumours. N Engl J Med 1993;12:4481-7.