Effective transduction and stable transgene expression in human blood cells by a third-generation lentiviral vector

Gene Therapy

Volumn 10, Issue 17, 2003, Pages 1446-1457

  Bai, Y ^a,f   Soda, Y ^a,b   Izawa, K ^a   Tanabe, T ^a,c   Kang, X ^a   Tojo, A ^a   Hoshino, H ^b   Miyoshi, H ^d,f   Asano, S ^a   Tani, K ^a,e  

^a THE UNIVERSITY OF TOKYO   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

^f INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

Gene transduction; Hematopoietic cell; Human blood cell; Leukemia; Third generation lentiviral vector

Indexed keywords

CD34 ANTIGEN; DNA; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; VIRUS VECTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BLOOD CELL; CANCER CELL CULTURE; CANCER PATIENT; CHRONIC MYELOID LEUKEMIA; COLONY FORMING CELL; CONTROLLED STUDY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENETIC STABILITY; GENETIC TRANSDUCTION; HEMATOLOGIC DISEASE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INTERMETHOD COMPARISON; LEUKEMIA; MOLONEY LEUKEMIA ONCOVIRUS; MULTIPLE MYELOMA; MYELODYSPLASTIC SYNDROME; MYELOMA; PERIPHERAL LYMPHOCYTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TRANSGENE; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM; VIRUS DNA CELL DNA INTERACTION; VIRUS INACTIVATION;

CELLS, CULTURED; GENE EXPRESSION; GENE THERAPY; GENETIC ENGINEERING; GENETIC VECTORS; HEMATOLOGIC DISEASES; HEMATOPOIETIC STEM CELLS; HIV-1; HUMANS; LEUKEMIA; MOLONEY MURINE LEUKEMIA VIRUS; MULTIPLE MYELOMA; TIME FACTORS; TRANSDUCTION, GENETIC; TRANSGENES; TUMOR CELLS, CULTURED;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRUS; MOLONEY MURINE LEUKEMIA VIRUS; MURINAE; MURINE LEUKEMIA VIRUS; ONCOVIRINAE; RNA VIRUSES;

EID: 0043026960     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302026     Document Type: Article

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