μ-Opioid-induced desensitization of opioid receptor-like 1 and μ-opioid receptors: Differential intracellular signaling determines receptor sensitivity

Journal of Pharmacology and Experimental Therapeutics

Volumn 306, Issue 3, 2003, Pages 965-972

  Mandyam, Chitra D ^a,b   Thakker, Deepak R ^a   Standifer, Kelly M ^a  

^a UNIVERSITY OF HOUSTON   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYCLIC AMP; DNA; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; ISOENZYME; MU OPIATE RECEPTOR; OPIATE RECEPTOR; OPIOID RECEPTOR LIKE 1 RECEPTOR; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; UNCLASSIFIED DRUG; NOCICEPTIN RECEPTOR; OPIATE PEPTIDE;

ANALGESIA; ARTICLE; CELL MEMBRANE TRANSPORT; CELL TYPE; CONTROLLED STUDY; DESENSITIZATION; ENZYME INACTIVATION; HUMAN; HUMAN CELL; HYPERALGESIA; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; PROTEIN TRANSPORT; RECEPTOR DOWN REGULATION; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY; CELL CULTURE; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; HUMANS; OPIOID PEPTIDES; RECEPTOR CROSS-TALK; RECEPTORS, OPIOID; RECEPTORS, OPIOID, MU; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0042934084     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.051599     Document Type: Article

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