G protein-coupled receptor kinase 2 mediates μ-opioid receptor desensitization in GABAergic neurons of the nucleus raphe magnus

Journal of Neurochemistry

Volumn 77, Issue 2, 2001, Pages 435-444

  Li, Allen H ^a   Wang, Hung Li ^b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

opioid receptor; DAMGO; GABAergic neuron; GRK2; Homologous desensitization; Nucleus raphe magnus

Indexed keywords

4 AMINOBUTYRIC ACID; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE 2; GLUTAMATE DECARBOXYLASE; MORPHINE; MU OPIATE RECEPTOR; POTASSIUM CHANNEL; POTASSIUM ION; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; GABAERGIC TRANSMISSION; HYPERPOLARIZATION; NERVE CELL; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN BINDING; RAPHE MAGNUS NUCLEUS; RAT; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD DORSAL HORN;

AMINO ACID SEQUENCE; ANALGESICS, OPIOID; ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; BINDING SITES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DRUG TOLERANCE; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; GAMMA-AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; ION TRANSPORT; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS; OLIGOPEPTIDES; PAIN; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; POTASSIUM; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPINAL CORD;

ANIMALIA;

EID: 0035048317     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00267.x     Document Type: Article

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