-
3
-
-
0343580507
-
2A receptor occupancy in the human brain after a single oral dose of the putative antipsychotic drug MDL 100,907 measured by positron emission tomography
-
published erratum appears in Neuropsychopharmacology 1998 Aug; 19 (2): 161
-
2A receptor occupancy in the human brain after a single oral dose of the putative antipsychotic drug MDL 100,907 measured by positron emission tomography (published erratum appears in Neuropsychopharmacology 1998 Aug; 19 (2): 161). Neuropsychopharmacology 1997; 17: 175-185
-
(1997)
Neuropsychopharmacology
, vol.17
, pp. 175-185
-
-
Gründer, G.1
Yokoi, F.2
Offord, S.J.3
Ravert, H.T.4
Dannals, R.F.5
Salzmann, J.K.6
Szymanski, S.7
Wilson, P.D.8
Howard, D.R.9
Wong, D.F.10
-
4
-
-
0035157572
-
Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: A [(11)C]DASB PET imaging study
-
Meyer JH, Wilson AA, Ginovart N, Goulding V, Hussey D, Hood K, Houle S. Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: a [(11)C]DASB PET imaging study. Am J Psychiatry 2001; 158: 1843-1849
-
(2001)
Am J Psychiatry
, vol.158
, pp. 1843-1849
-
-
Meyer, J.H.1
Wilson, A.A.2
Ginovart, N.3
Goulding, V.4
Hussey, D.5
Hood, K.6
Houle, S.7
-
5
-
-
0035983682
-
Dopamine D(2) and D(3) receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597). A study using positron emission tomography and [11C]raclopride
-
Yokoi F, Gründer G, Biziere K, Stephane M, Dogan AS, Dannals RF, Ravert H, Suri A, Bramer S, Wong DF. Dopamine D(2) and D(3) Receptor Occupancy in Normal Humans Treated with the Antipsychotic Drug Aripiprazole (OPC 14597). A Study Using Positron Emission Tomography and [11C]Raclopride. Neuropsychopharmacology 2002; 27: 248-259
-
(2002)
Neuropsychopharmacology
, vol.27
, pp. 248-259
-
-
Yokoi, F.1
Gründer, G.2
Biziere, K.3
Stephane, M.4
Dogan, A.S.5
Dannals, R.F.6
Ravert, H.7
Suri, A.8
Bramer, S.9
Wong, D.F.10
-
6
-
-
0024411912
-
Dopamine blockade and clinical response: Evidence for two biological subgroups of schizophrenia
-
Wolkin A, Barouche F, Wolf AP, Rotrosen J, Fowler JS, Shiue CY, Cooper TB, Brodie JD. Dopamine blockade and clinical response: evidence for two biological subgroups of schizophrenia. Am J Psychiatry 1989; 146: 905-908
-
(1989)
Am J Psychiatry
, vol.146
, pp. 905-908
-
-
Wolkin, A.1
Barouche, F.2
Wolf, A.P.3
Rotrosen, J.4
Fowler, J.S.5
Shiue, C.Y.6
Cooper, T.B.7
Brodie, J.D.8
-
7
-
-
0034025771
-
Relationship between dopamine D(2) occupancy, clinical response, and side effects: A double-blind PET study of first-episode schizophrenia
-
Kapur S, Zipursky R, Jones C, Remington G, Houle S. Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia. Am J Psychiatry 2000; 157: 514-520
-
(2000)
Am J Psychiatry
, vol.157
, pp. 514-520
-
-
Kapur, S.1
Zipursky, R.2
Jones, C.3
Remington, G.4
Houle, S.5
-
9
-
-
0005122819
-
Meta-analysis of the efficacy of aripiprazole in schizophrenia
-
Lieberman JA, Carson WH, Saha A, Stringfellow JC, Archibald DG, Kujawa MJ, Ulwamoto T. Meta-analysis of the efficacy of aripiprazole in schizophrenia. Int J Neuropsychopharmacol 2002; 5 (Suppl 1): 186
-
(2002)
Int J Neuropsychopharmacol
, vol.5
, Issue.SUPPL. 1
, pp. 186
-
-
Lieberman, J.A.1
Carson, W.H.2
Saha, A.3
Stringfellow, J.C.4
Archibald, D.G.5
Kujawa, M.J.6
Ulwamoto, T.7
-
10
-
-
0003149756
-
Efficacy of aripiprazole in psychotic disorders: Comparison with haloperidol and placebo
-
Kane J, Ingenito G, Ali M. Efficacy of aripiprazole in psychotic disorders: Comparison with haloperidol and placebo. Schizophr Res 2000; 41: 39
-
(2000)
Schizophr Res
, vol.41
, pp. 39
-
-
Kane, J.1
Ingenito, G.2
Ali, M.3
-
11
-
-
0001612909
-
Aripiprazole, a new atypical antipsychotic: Phase 2 clinical trial result
-
Petrie JL, Saha AR, McEvoy JP. Aripiprazole, a new atypical antipsychotic: Phase 2 clinical trial result. Eur Neuropsychopharmacol 1997; 7 Suppl 2: 227
-
(1997)
Eur Neuropsychopharmacol
, vol.7
, Issue.SUPPL.
, pp. 227
-
-
Petrie, J.L.1
Saha, A.R.2
McEvoy, J.P.3
-
12
-
-
0000819064
-
Efficacy and safety of aripiprazole and risperidone vs. placebo in patients with schizophrenia and schizoaffective disorder
-
Saha AR, McQuade R, Carson WH, Ali MW, Dunbar GC, Ingenito G. Efficacy and safety of aripiprazole and risperidone vs. placebo in patients with schizophrenia and schizoaffective disorder. World J Biol Psych 2001; 2 Suppl 1: 305
-
(2001)
World J Biol Psych
, vol.2
, Issue.SUPPL. 1
, pp. 305
-
-
Saha, A.R.1
McQuade, R.2
Carson, W.H.3
Ali, M.W.4
Dunbar, G.C.5
Ingenito, G.6
-
13
-
-
0000649069
-
Safety and tolerability of aripiprazole at doses higher than 30 mg
-
Saha AR, Ali M, Ingenito GG, Wilber R, Luo X, Bramer S. Safety and tolerability of aripiprazole at doses higher than 30 mg. Int J Neuropsychopharmacol 2002; 5 (Suppl 1): 185
-
(2002)
Int J Neuropsychopharmacol
, vol.5
, Issue.SUPPL. 1
, pp. 185
-
-
Saha, A.R.1
Ali, M.2
Ingenito, G.G.3
Wilber, R.4
Luo, X.5
Bramer, S.6
-
14
-
-
0029023002
-
7-{4-[4-(2,3-dichlorophenyl)-1-piperazinyl}butyloxy]-3,4-dihydro-2(1H) -quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity
-
Kikuchi T, Tottori K, Uwahodo Y, Hirose T, Miwa T, Oshiro Y, Morita S. 7-{4-[4-(2,3-dichlorophenyl)-1-piperazinyl}butyloxy]-3,4-dihydro-2(1H) -quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity. J Pharmacol Exp Ther 1995; 274: 329-336
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 329-336
-
-
Kikuchi, T.1
Tottori, K.2
Uwahodo, Y.3
Hirose, T.4
Miwa, T.5
Oshiro, Y.6
Morita, S.7
-
15
-
-
0033151286
-
Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes
-
Lawler CP, Prioleau C, Lewis MM, Mak C, Jiang D, Schetz JA, Gonzalez AM, Sibley DR, Mailman RB. Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes. Neuropsychopharmacology 1999; 20: 612-627
-
(1999)
Neuropsychopharmacology
, vol.20
, pp. 612-627
-
-
Lawler, C.P.1
Prioleau, C.2
Lewis, M.M.3
Mak, C.4
Jiang, D.5
Schetz, J.A.6
Gonzalez, A.M.7
Sibley, D.R.8
Mailman, R.B.9
-
16
-
-
0030430029
-
Effects of the novel antipsychotic agent 7-{4-[4-(2,3-dichlorophenyl)-1- piperazinyl]butyloxy}-3,4-dihydro-2(1H)-quinolinone (OPC-14597) on prolactin release from the rat anterior pituitary gland
-
Inoue T, Domae M, Yamada K, Furukawa T. Effects of the novel antipsychotic agent 7-{4-[4-(2,3-dichlorophenyl)-1- piperazinyl]butyloxy}-3,4-dihydro-2(1H)-quinolinone (OPC-14597) on prolactin release from the rat anterior pituitary gland. J Pharmacol Exp Ther 1996; 277: 137-144
-
(1996)
J Pharmacol Exp Ther
, vol.277
, pp. 137-144
-
-
Inoue, T.1
Domae, M.2
Yamada, K.3
Furukawa, T.4
-
17
-
-
0031577960
-
Aripiprazole, a novel antipsychotic drug, inhibits quinpirole-evoked GTPase activity but does not up-regulate dopamine D2 receptor following repeated treatment in the rat striatum
-
Inoue A, Miki S, Seto M, Kikuchi T, Morita S, Ueda H, Misu Y, Nakata Y. Aripiprazole, a novel antipsychotic drug, inhibits quinpirole-evoked GTPase activity but does not up-regulate dopamine D2 receptor following repeated treatment in the rat striatum. Eur J Pharmacol 1997; 321: 105-111
-
(1997)
Eur J Pharmacol
, vol.321
, pp. 105-111
-
-
Inoue, A.1
Miki, S.2
Seto, M.3
Kikuchi, T.4
Morita, S.5
Ueda, H.6
Misu, Y.7
Nakata, Y.8
-
18
-
-
0036089687
-
Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors
-
Burris KD, Molski TF, Xu C, Ryan E, Tottori K, Kikuchi T, Yocca FD, Molinoff PB. Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors. J Pharmacol Exp Ther 2002; 302: 381-389
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 381-389
-
-
Burris, K.D.1
Molski, T.F.2
Xu, C.3
Ryan, E.4
Tottori, K.5
Kikuchi, T.6
Yocca, F.D.7
Molinoff, P.B.8
-
19
-
-
0023265884
-
Relationship between receptor occupancy and response at striatal dopamine autoreceptors
-
Meller E, Bohmaker K, Namba Y, Friedhoff AJ, Goldstein M. Relationship between receptor occupancy and response at striatal dopamine autoreceptors. Mol Pharmacol 1987; 31: 592-598
-
(1987)
Mol Pharmacol
, vol.31
, pp. 592-598
-
-
Meller, E.1
Bohmaker, K.2
Namba, Y.3
Friedhoff, A.J.4
Goldstein, M.5
-
20
-
-
0023718740
-
Absence of receptor reserve at striatal dopamine receptors regulating cholinergic neuronal activity
-
Meller E, Enz A, Goldstein M. Absence of receptor reserve at striatal dopamine receptors regulating cholinergic neuronal activity. Eur J Pharmacol 1988; 155: 151-154
-
(1988)
Eur J Pharmacol
, vol.155
, pp. 151-154
-
-
Meller, E.1
Enz, A.2
Goldstein, M.3
-
21
-
-
0027066954
-
Dopamine autoreceptor agonists in the treatment of schizophrenia and major depression
-
Benkert O, Gründer G, Wetzel H. Dopamine autoreceptor agonists in the treatment of schizophrenia and major depression. Pharmacopsychiatry 1992; 25: 254-260
-
(1992)
Pharmacopsychiatry
, vol.25
, pp. 254-260
-
-
Benkert, O.1
Gründer, G.2
Wetzel, H.3
-
22
-
-
0027930558
-
Roxindole, a dopamine autoreceptor agonist, in the treatment of positive and negative schizophrenic symptoms
-
Wetzel H, Hillert A, Gründer G, Benkert O. Roxindole, a dopamine autoreceptor agonist, in the treatment of positive and negative schizophrenic symptoms. Am J Psychiatry 1994; 151: 1499 - 1502
-
(1994)
Am J Psychiatry
, vol.151
, pp. 1499-1502
-
-
Wetzel, H.1
Hillert, A.2
Gründer, G.3
Benkert, O.4
-
23
-
-
0035188542
-
Welche eigenschaften machen ein neuroleptikum "atypisch"
-
Gründer G, Vernaleken I, Benkert O. Welche Eigenschaften machen ein Neuroleptikum "atypisch". Nervenarzt 2001; 72: 833-843
-
(2001)
Nervenarzt
, vol.72
, pp. 833-843
-
-
Gründer, G.1
Vernaleken, I.2
Benkert, O.3
-
24
-
-
0020652913
-
Preliminary studies of human cortical 5-HT2 receptors and their involvement in schizophrenia and neuroleptic drug action
-
Reynolds GP, Rossor MN, Iversen LL. Preliminary studies of human cortical 5-HT2 receptors and their involvement in schizophrenia and neuroleptic drug action. J Neural Transm 1983; 18 (Suppl): 273-277
-
(1983)
J Neural Transm
, vol.18
, Issue.SUPPL.
, pp. 273-277
-
-
Reynolds, G.P.1
Rossor, M.N.2
Iversen, L.L.3
-
30
-
-
0033957627
-
Non-equipotent doses partly explain differences among antipsychotics - Implications of PET studies
-
Nyberg S, Farde L. Non-equipotent doses partly explain differences among antipsychotics - implications of PET studies [comment]. Psychopharmacology Berl 2000; 148: 22-23
-
(2000)
Psychopharmacology Berl
, vol.148
, pp. 22-23
-
-
Nyberg, S.1
Farde, L.2
-
31
-
-
0035660215
-
Dopamine D(2) receptors and their role in atypical antipsychotic action: Still necessary and may even be sufficient
-
Kapur S, Remington G. Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient. Biol Psychiatry 2001; 50: 873-883
-
(2001)
Biol Psychiatry
, vol.50
, pp. 873-883
-
-
Kapur, S.1
Remington, G.2
-
32
-
-
0036161972
-
Amisulpride, an unusual "atypical" antipsychotic: A meta-analysis of randomized controlled trials
-
Leucht S, Pitschel-Walz G, Engel RR, Kissling W. Amisulpride, an unusual "atypical" antipsychotic: a meta-analysis of randomized controlled trials. Am J Psychiatry 2002; 159: 180-190
-
(2002)
Am J Psychiatry
, vol.159
, pp. 180-190
-
-
Leucht, S.1
Pitschel-Walz, G.2
Engel, R.R.3
Kissling, W.4
-
33
-
-
0036278293
-
Prolactin secretion is not a core dimension of atypicality
-
Gründer G, Benkert O. Prolactin secretion is not a core dimension of atypicality. Psychopharmacology (letter) 2002; 162: 93
-
(2002)
Psychopharmacology (Letter)
, vol.162
, pp. 93
-
-
Gründer, G.1
Benkert, O.2
-
34
-
-
0030933627
-
Psychopharmacological profile of amisulpride: An antipsychotic drug with presynaptic D2/D3 dopamine receptor antagonist activity and limbic selectivity
-
Perrault G, Depoortere R, Morel E, Sanger DJ, Scatton B. Psychopharmacological profile of amisulpride: an antipsychotic drug with presynaptic D2/D3 dopamine receptor antagonist activity and limbic selectivity. J Pharmacol Exp Ther 1997; 280: 73-82
-
(1997)
J Pharmacol Exp Ther
, vol.280
, pp. 73-82
-
-
Perrault, G.1
Depoortere, R.2
Morel, E.3
Sanger, D.J.4
Scatton, B.5
-
35
-
-
0030791026
-
Amisulpride: From animal pharmacology to therapeutic action
-
Scatton B, Claustre Y, Cudennec A, Oblin A, Perrault G, Sanger DJ, Schoemaker H. Amisulpride: from animal pharmacology to therapeutic action. Int Clin Psychopharmacol 1997; 12 Suppl 2: 29-36
-
(1997)
Int Clin Psychopharmacol
, vol.12
, Issue.SUPPL. 2
, pp. 29-36
-
-
Scatton, B.1
Claustre, Y.2
Cudennec, A.3
Oblin, A.4
Perrault, G.5
Sanger, D.J.6
Schoemaker, H.7
-
36
-
-
8244235137
-
Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity
-
Schoemaker H, Claustre Y, Fage D, Rouquier L, Chergui K, Curet O, Oblin A, Gonon F, Carter C, Benavides J, Scatton B. Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity. J Pharmacol Exp Ther 1997; 280: 83-97
-
(1997)
J Pharmacol Exp Ther
, vol.280
, pp. 83-97
-
-
Schoemaker, H.1
Claustre, Y.2
Fage, D.3
Rouquier, L.4
Chergui, K.5
Curet, O.6
Oblin, A.7
Gonon, F.8
Carter, C.9
Benavides, J.10
Scatton, B.11
-
37
-
-
0036221550
-
Atypical antipsychotics: Mechanisms of action
-
Seeman P. Atypical antipsychotics: mechanisms of action. Can J Psychiatry 2002; 47: 27-38
-
(2002)
Can J Psychiatry
, vol.47
, pp. 27-38
-
-
Seeman, P.1
-
38
-
-
0042847563
-
-
submitted
-
Vernaleken I, Siessmeier T, Buchholz H-G, Härtter S, Hiemke C, Stoeter P, Rösch F, Bartenstein P, Gründer G. High striatal occupancy of D2-like dopamine receptors by amisulpride in brain of schizophrenic patients: mechanism of action. submitted 2003
-
(2003)
High Striatal Occupancy of D2-Like Dopamine Receptors by Amisulpride in Brain of Schizophrenic Patients: Mechanism of Action
-
-
Vernaleken, I.1
Siessmeier, T.2
Buchholz, H.-G.3
Härtter, S.4
Hiemke, C.5
Stoeter, P.6
Rösch, F.7
Bartenstein, P.8
Gründer, G.9
-
39
-
-
7144235791
-
Amisulpride versus flupentixol in schizophrenia with predominantly positive symptomatology - A double-blind controlled study comparing a selective D2-like antagonist to a mixed D1-/D2-like antagonist
-
The Amisulpride Study Group
-
Wetzel H, Gründer G, Hillert A, Philipp M, Gattaz WF, Sauer H, Adler GJS, Rein W, Benkert O. Amisulpride versus flupentixol in schizophrenia with predominantly positive symptomatology - a double-blind controlled study comparing a selective D2-like antagonist to a mixed D1-/D2-like antagonist. The Amisulpride Study Group. Psychopharmacology Berl 1998; 137: 223-232
-
(1998)
Psychopharmacology Berl
, vol.137
, pp. 223-232
-
-
Wetzel, H.1
Gründer, G.2
Hillert, A.3
Philipp, M.4
Gattaz, W.F.5
Sauer, H.6
Adler, G.J.S.7
Rein, W.8
Benkert, O.9
-
40
-
-
0032973806
-
Rapid release of antipsychotic drugs from dopamine D2 receptors: An explanation for low receptor occupancy and early clinical relapse upon withdrawal of clozapine or quetiapine
-
Seeman P, Tallerico T. Rapid release of antipsychotic drugs from dopamine D2 receptors: an explanation for low receptor occupancy and early clinical relapse upon withdrawal of clozapine or quetiapine. Am J Psychiatry 1999; 156: 876-884
-
(1999)
Am J Psychiatry
, vol.156
, pp. 876-884
-
-
Seeman, P.1
Tallerico, T.2
|