Time course of 5-HT(2A) receptor occupancy in the human brain after a single oral dose of the putative antipsychotic drug MDL 100,907 measured by positron emission tomography

Neuropsychopharmacology

Volumn 17, Issue 3, 1997, Pages 175-185

  Gründer, Gerhard ^a,d   Yokoi, Fuji ^a   Offord, Steve J ^c   Ravert, Hayden T ^a   Dannals, Robert F ^a   Salzmann, Joanne K ^c   Szymanski, Sally ^a   Wilson, P David ^b   Howard, Daniel R ^c   Wong, Dean F ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c SANOFI   (France)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

5 HT2 receptors; Antipsychotic drugs; Human; MDL 100,907; Positron emission tomography

Indexed keywords

ALPHA (2,3 DIMETHOXYPHENYL) 1 [2 (4 FLUOROPHENYL)ETHYL] 4 PIPERIDINEMETHANOL; NEUROLEPTIC AGENT; SEROTONIN 2A RECEPTOR; TRACER;

ADULT; ARTICLE; BRAIN; DRUG BLOOD LEVEL; DRUG RECEPTOR BINDING; FEMALE; FRONTAL CORTEX; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR OCCUPANCY;

EID: 0343580507     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(97)00044-4     Document Type: Article

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