Streptococcal preparation OK-432: A new maturation factor of monocyte-derived dendritic cells for clinical use

Cancer Immunology, Immunotherapy

Volumn 52, Issue 9, 2003, Pages 561-568

  Kuroki, Hideo ^a   Morisaki, Takashi ^a   Matsumoto, Kotaro ^a   Onishi, Hideya ^a   Baba, Eishi ^a   Tanaka, Masao ^a   Katano, Mitsuo ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

IFN ; IL 12 p70; Monocyte derived dendritic cells; OK 432; Tumour immunotherapy

Indexed keywords

B7 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; CYTOCHALASIN B; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MESSENGER RNA; NEUTRALIZING ANTIBODY; PICIBANIL; PROSTAGLANDIN E2; PROTEIN P70; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN EXPRESSION; ARTICLE; CANCER IMMUNOTHERAPY; CELL MATURATION; CYTOKINE RELEASE; DENDRITIC CELL; GOOD MANUFACTURING PRACTICE; HUMAN; HUMAN CELL; JAPAN; LYMPHOCYTE PROLIFERATION; MONOCYTE; PRIORITY JOURNAL; STREPTOCOCCUS; T LYMPHOCYTE; VACCINATION;

CELLS, CULTURED; CYTOCHALASIN B; DENDRITIC CELLS; ENZYME ACTIVATION; HUMANS; INTERFERON TYPE II; INTERLEUKIN-12; LYMPHOCYTE ACTIVATION; MONOCYTES; PICIBANIL; PROTEIN-SERINE-THREONINE KINASES; T-LYMPHOCYTES;

EID: 0042856241     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-003-0394-7     Document Type: Article

References (45)

1. Abdi K (2002) IL-12: the role of p40 versus p75. Scand J Immunol 56:1
2. 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes. J Exp Med 188:1359
3. Banchereau J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ, Pulendran B, Palucka K (2000) Immunobiology of dendritic cells. Annu Rev Immunol 18:767
4. Banchereau J, Steinman RM (1998) Dendritic cells and the control of immunity. Nature 392:245
5. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156
6. Denk A, Wirth T, Baumann B (2000) NF-kappaB transcription factors: critical regulators of hematopoiesis and neuronal survival. Cytokine Growth Factor Rev 11:303
7. De Waal Malefyt R, Figdor CG, Huijbens R, Mohan-Peterson S, Bennett B, Culpepper J, Dang W, Zurawski G, de Vries JE (1993) Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes: comparison with IL-4 and modulation by IFN-gamma or IL-10. J Immunol 151:6370
8. Fong L, Engleman EG (2000) Dendritic cells in cancer immunotherapy. Annu Rev Immunol 18:245
9. Fukao T, Matsuda S, Koyasu S (2000) Synergistic effects of IL-4 and IL-18 on IL-12-dependent IFN-gamma production by dendritic cells. J Immunol 164:64
10. Grumont R, Hochrein H, O'Keeffe M, Gugasyan R, White C, Caminschi I, Cook W, Gerondakis S (2001) c-Rel regulates interleukin 12 p70 expression in CDS(+) dendritic cells by specifically inducing p35 gene transcription. J Exp Med 194:1021
11. Hayashi Y, Torisu M (1990) New approach to management of malignant ascites with streptococcal preparation OK-432: III. OK-432 attracts natural killer cells through a chemotactic factor released from activated neutrophils. Surgery 107:74
12. Hochrein H, Shortman K, Vremec D, Scott B, Hertzog P, O'Keeffe M (2001) Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets. J Immunol 166:5448
13. Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y, Takeda K, Akira S (1999) Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol 162:3749
14. 2 is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer. Blood 97:3466
15. Katano M, Morisaki T (1998) The past, the present and future of the OK-432 therapy for patients with malignant effusions. Anticancer Res 18:3917
16. Katano M, Nakamura M, Kuwahara A, Fujimoto K, Matsunaga H, Miyazaki K, Morisaki T (1998) Expression of interleukin (IL)-12 mRNA in gastric carcinoma specimens: cellular antitumor immune responses. J Surg Oncol 67:11
17. Luft T, Jefford M, Luetjens P, Hochrein H, Masterman KA, Maliszewski C, Shortman K, Cebon J, Maraskovsky E (2002) IL-1 beta enhances CD40 ligand-mediated cytokine secretion by human dendritic cells (DC): a mechanism for T cell-independent DC activation. J Immunol 168:713
18. 2 regulates the migratory capacity of specific DC subsets. Blood 100:1362
19. Lyakh LA, Koski GK, Telford W, Gress RE, Cohen PA, Rice NR (2000) Bacterial lipopolysaccharide, TNF-alpha, and calcium ionophore under serum-free conditions promote rapid dendritic cell-like differentiation in CD14+ monocytes through distinct pathways that activate NK-kappa B. J Immunol 165:3647
20. Marovich MA, McDowell MA, Thomas EK, Nutman TB (2000) IL-12p70 production by Leishmania major-harboring human dendritic cells is a CD40/CD40 ligand-dependent process. J Immunol 164:5858
21. Miyata S, Furuya K, Nakai S, Bun H, Kiyohara T (1999) Morphological plasticity and rearrangement of cytoskeletons in pituicytes cultured from adult rat neurohypophysis. Neurosci Res 33:299
22. Morse MA, Lyerly HK (2000) Dendritic cell-based immunization for cancer therapy. Adv Exp Med Biol 465:335
23. Nagayama H, Sato K, Kawasaki H, Enomoto M, Morimoto C, Tadokoro K, Juji T, Asano S, Takahashi TA (2000) IL-12 responsiveness and expression of IL-12 receptor in human peripheral blood monocyte-derived dendritic cells. J Immunol 165:59
24. O'Neill GP, Ford-Hutchinson AW (1993) Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett 330:156
25. O'Sullivan BJ, Thomas R (2002) CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB. J Immunol 168:5491
26. Ohteki T, Fukao T, Suzue K, Maki C, Ito M, Nakamura M, Koyasu S (1999) Interleukin 12-dependent interferon gamma production by CD8α+ lymphoid dendritic cells. J Exp Med 189:1981
27. Okada N, Saito T, Mori K, Masunaga Y, Fujii Y, Fujita J, Fujimoto K, Nakanishi T, Tanaka K, Nakagawa S, Mayumi T, Fujita T, Yamamoto A (2001) Effects of lipofectin-antigen complexes on major histocompatibility complex class I-restricted antigen presentation pathway in murine dendritic cells and on dendritic cell maturation. Biochim Biophys Acta 1527:97
28. Okamoto H, Shoin S, Koshimura S, Shimizu R (1967) Studies on the anticancer and streptolysin S-forming abilities of hemolytic streptococci. Jpn J Microbiol 11:323
29. Okamoto M, Kaji R, Kasetani H, Yoshida H, Moriya Y, Saito M, Sato M (1993) Purification and characterization of interferon-gamma-inducing molecule of OK-432, a penicillin-killed streptococcal preparation, by monoclonal antibody neutralizing interferon-gamma-inducing activity of OK-432. J Immunother 13:232
30. Okamoto M, Oshikawa T, Ohe G, Nishikawa H, Furuichi S, Tano T, Moriya Y, Saito M, Sato M (2001) Severe impairment of anti-cancer effect of lipoteichoic acid-related molecule isolated from a penicillin-killed Streptococcus pyogenes in toll-like receptor 4-deficient mice. Int Immunopharmacol 1:1789
31. Onishi H, Morisaki T, Kuga H, Katano M, Doi F, Uchiyama A, Sugitani A, Wada J, Chijiiwa K, Tanaka M (2002) A large quantity of CD3-/CD19-/CD16- lymphocytes in malignant pleural effusion from a patient with recurrent cholangio cell carcinoma. Immunol Invest 31:121
32. Rieser C, Bock G, Klocker H, Bartsch G, Thurnher M (1997) Prostaglandin E2 and tumor necrosis factor alpha cooperate to activate human dendritic cells: synergistic activation of interleukin 12 production. J Exp Med 186:1603
33. Robinson DS, O'Garra A (2002) Further checkpoints in Th1 development. Immunity 16:755
34. Sallusto F, Lanzavecchia A (1994) Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 179:1109
35. Sallusto F, Cella M, Danieli C, Lanzavecchia A (1995) Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med 182:389
36. Sasaki N, Morisaki T, Hashizume K, Yao T, Tsuneyoshi M, Noshiro H, Nakamura K, Yamanaka T, Uchiyama A, Tanaka M, Katano M (2001) Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue. Clin Cancer Res 7:4136
37. Schulz O, Edwards AD, Schito M, Aliberti J, Manickasingham S, Sher A, Reis eSousaC (2000) CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity 13:453
38. Snijders A, Hilkens CM, van der PouwKraanTC, Engel M, Aarden LA, Kapsenberg ML (1996) Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit. J Immunol 156:1207
39. Sousa CR, Hieny S, Scharton-Kersten T, Jankovic D, Charest H, Germain RN, Sher A (1997) In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas. J Exp Med 186:1819
40. Stober D, Schirmbeck R, Reimann J (2001) IL-12/IL-18-dependent IFN-gamma release by murine dendritic cells. J Immunol 167:957
41. Trinchieri G (1995) Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol 13:251
42. Urban BC, Willcox N, Roberts DJ (2001) A role for CD36 in the regulation of dendritic cell function. Proc Natl Acad Sci U S A 98:8750
43. Vidal V, Dewulf J, Bahr GM (2001) Enhanced maturation and functional capacity of monocyte-derived immature dendritic cells by the synthetic immunomodulator Murabutide. Immunology 103:479
44. Wesa AK, Galy A (2001) IL-1 beta induces dendritic cells to produce IL-12. Int Immunol 13:1053
45. Zhou LJ, Tedder TF (1996) CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc Natl Acad Sci USA 93:2588