Effects of lipofectin-antigen complexes on major histocompatibility complex class I-restricted antigen presentation pathway in murine dendritic cells and on dendritic cell maturation

Biochimica et Biophysica Acta - General Subjects

Volumn 1527, Issue 3, 2001, Pages 97-101

  Okada, Naoki ^a   Saito, Tomomi ^a   Mori, Kohei ^a   Masunaga, Yasushige ^a   Fujii, Yoshihiro ^a   Fujita, Junko ^a   Fujimoto, Kyoko ^a   Nakanishi, Tsuyoshi ^b   Tanaka, Keiichi ^b   Nakagawa, Shinsaku ^b   Mayumi, Tadanori ^b   Fujita, Takuya ^a   Yamamoto, Akira ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Antigen presentation; Dendritic cell; Immunotherapy; Lipofectin; Maturation

Indexed keywords

ANTIGEN; INTERLEUKIN 12; LIPOFECTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MESSENGER RNA; PROTEASOME; PROTEIN P40;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CATALYSIS; CELL MATURATION; CELL TRANSPORT; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENDRITIC CELL; ENDOCYTOSIS; GENE EXPRESSION; GOLGI COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACETYLCYSTEINE; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; BREFELDIN A; CELL LINE; CELL SURVIVAL; CHLOROQUINE; CYTOCHALASIN B; DENDRITIC CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS I; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; OVALBUMIN; PHOSPHATIDYLETHANOLAMINES; TIME FACTORS;

MURINAE;

EID: 0035882330     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4165(01)00160-X     Document Type: Article

References (14)

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2. Dendritic cells and the control of immunity
3. Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes
4. Epidermal dendritic cells induce potent antigen-specific CTL-mediated immunity
5. Immunotherapeutic potential of tumor antigen-pulsed and unpulsed dendritic cells generated from murine bone marrow
6. Administration route-dependent vaccine efficiency of murine dendritic cells pulsed with antigens
7. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules
8. Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules
9. Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells
10. Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells
11. Class I-restricted presentation of exogenous antigen acquired by Fcγ receptor-mediated endocytosis is regulated in dendritic cells
12. Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage
13. Enhanced dendritic cell maturation by TNF-α or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immune responses in vivo
14. A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-γ treatment