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Volumn 64, Issue 2, 2003, Pages 407-414

Aspirin protects Caco-2 cells from apoptosis after serum deprivation through the activation of a phosphatidylinositol 3-kinase/AKT/p21Cip/WAF1 pathway

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLSALICYLIC ACID; ANTINEOPLASTIC AGENT; ETOPOSIDE; MITOGEN ACTIVATED PROTEIN KINASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P21;

EID: 0042844642     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.2.407     Document Type: Article
Times cited : (28)

References (39)
  • 1
    • 0029040581 scopus 로고
    • Growth inhibition of rat glioma cells in vitro and in vivo by aspirin
    • Aas AT, Tonnessen TI, Brun A, and Salford LG (1995) Growth inhibition of rat glioma cells in vitro and in vivo by aspirin. J Neurooncol 24:171-180.
    • (1995) J Neurooncol , vol.24 , pp. 171-180
    • Aas, A.T.1    Tonnessen, T.I.2    Brun, A.3    Salford, L.G.4
  • 2
    • 0033613944 scopus 로고    scopus 로고
    • 2/M checkpoint arrest in cells exposed to ionizing radiation
    • 2/M checkpoint arrest in cells exposed to ionizing radiation. J Biol Chem 274:2732-2742.
    • (1999) J Biol Chem , vol.274 , pp. 2732-2742
    • Abbott, D.W.1    Holt, J.T.2
  • 3
    • 0037614262 scopus 로고    scopus 로고
    • Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells
    • Aliaga JC, Deschenes C, Beaulieu JF, Calvo EL, and Rivard N (1999) Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells. Am J Physiol 277:G631-G641.
    • (1999) Am J Physiol , vol.277
    • Aliaga, J.C.1    Deschenes, C.2    Beaulieu, J.F.3    Calvo, E.L.4    Rivard, N.5
  • 6
    • 0036312641 scopus 로고    scopus 로고
    • Downregulation of ERK2 is essential for the inhibition of radiation-induced cell death in HSP25 overexpressed L929 cells
    • Cho HN, Lee YJ, Cho CK, Lee SJ, and Lee YS (2002) Downregulation of ERK2 is essential for the inhibition of radiation-induced cell death in HSP25 overexpressed L929 cells. Cell Death Differ 9:448-456.
    • (2002) Cell Death Differ , vol.9 , pp. 448-456
    • Cho, H.N.1    Lee, Y.J.2    Cho, C.K.3    Lee, S.J.4    Lee, Y.S.5
  • 8
    • 0034676333 scopus 로고    scopus 로고
    • IGF-II/IGF receptor pathway up-regulates COX-2 mRNA expression and PGE2 synthesis in Caco-2 human colon carcinoma cells
    • Di Popolo A, Memoli A, Apicella A, Tuccillo C, di Palma A, Ricchi P, Acquaviva AM, and Zarrilli R (2000) IGF-II/IGF receptor pathway up-regulates COX-2 mRNA expression and PGE2 synthesis in Caco-2 human colon carcinoma cells. Oncogene 19:5517-5524.
    • (2000) Oncogene , vol.19 , pp. 5517-5524
    • Di Popolo, A.1    Memoli, A.2    Apicella, A.3    Tuccillo, C.4    Di Palma, A.5    Ricchi, P.6    Acquaviva, A.M.7    Zarrilli, R.8
  • 9
    • 0030980026 scopus 로고    scopus 로고
    • Inhibition of activator protein 1 activity and neoplastic transformation by aspirin
    • Dong Z, Huang C, Brown RE, and Ma WY (1997) Inhibition of activator protein 1 activity and neoplastic transformation by aspirin. J Biol Chem 272:9962-9970.
    • (1997) J Biol Chem , vol.272 , pp. 9962-9970
    • Dong, Z.1    Huang, C.2    Brown, R.E.3    Ma, W.Y.4
  • 10
    • 0029914705 scopus 로고    scopus 로고
    • Cell cycle protein suppression and p21 induction in differentiating Caco-2 cells
    • Evers BM, Ko TC, Li J, and Thompson EA (1996) Cell cycle protein suppression and p21 induction in differentiating Caco-2 cells. Am J Physiol 271:G722-G727.
    • (1996) Am J Physiol , vol.271
    • Evers, B.M.1    Ko, T.C.2    Li, J.3    Thompson, E.A.4
  • 11
    • 0031923788 scopus 로고    scopus 로고
    • Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line
    • Eves EM, Xiong W, Bellacosa A, Kennedy SG, Tsichlis PN, Rosner MR, and Hay N (1998) Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line. Mol Cell Biol 18:2143-2152.
    • (1998) Mol Cell Biol , vol.18 , pp. 2143-2152
    • Eves, E.M.1    Xiong, W.2    Bellacosa, A.3    Kennedy, S.G.4    Tsichlis, P.N.5    Rosner, M.R.6    Hay, N.7
  • 12
    • 0030587392 scopus 로고    scopus 로고
    • p21 (WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line
    • Gartel AL, Serfas MS, Gartel M, Goufman E, Wu GS, el-Deiry WS, and Tyner AL (1996) p21 (WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line. Exp Cell Res 227:171-181.
    • (1996) Exp Cell Res , vol.227 , pp. 171-181
    • Gartel, A.L.1    Serfas, M.S.2    Gartel, M.3    Goufman, E.4    Wu, G.S.5    El-Deiry, W.S.6    Tyner, A.L.7
  • 13
    • 0034984265 scopus 로고    scopus 로고
    • Human intestinal epithelial cell survival: Differentiation state-specific control mechanisms
    • Gauthier R, Harnois C, Drolet JF, Reed JC, Vezina A, and Vachon PH (2001) Human intestinal epithelial cell survival: differentiation state-specific control mechanisms. Am J Physiol 280:C1540-C1554.
    • (2001) Am J Physiol , vol.280
    • Gauthier, R.1    Harnois, C.2    Drolet, J.F.3    Reed, J.C.4    Vezina, A.5    Vachon, P.H.6
  • 14
    • 0029799831 scopus 로고    scopus 로고
    • Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation
    • Grilli M, Pizzi M, Memo M, and Spano PF (1996) Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation. Science (Wash DC) 274:1383-1385.
    • (1996) Science (Wash DC) , vol.274 , pp. 1383-1385
    • Grilli, M.1    Pizzi, M.2    Memo, M.3    Spano, P.F.4
  • 16
    • 0042816064 scopus 로고    scopus 로고
    • The salicylates
    • (JG Hardman JG, Limbird LE, and Molinoff RW eds), McGraw-Hill Companies, New York
    • Insel PA (2001) The salicylates, in Goodman and Gilman's The Pharmacological Basis of Therapeutics (JG Hardman JG, Limbird LE, and Molinoff RW eds) pp 696-703, McGraw-Hill Companies, New York.
    • (2001) Goodman and Gilman's the Pharmacological Basis of Therapeutics , pp. 696-703
    • Insel, P.A.1
  • 18
    • 0034624043 scopus 로고    scopus 로고
    • Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin Dl, cyclin A and proliferating cell nuclear antigen
    • Law BK, Waltner-Law ME, Entingh AJ, Chytil A, Aakre ME, Norgaard P, and Moses HL (2000) Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin Dl, cyclin A and proliferating cell nuclear antigen. J Biol Chem 275:38261-38267.
    • (2000) J Biol Chem , vol.275 , pp. 38261-38267
    • Law, B.K.1    Waltner-Law, M.E.2    Entingh, A.J.3    Chytil, A.4    Aakre, M.E.5    Norgaard, P.6    Moses, H.L.7
  • 19
    • 0034638844 scopus 로고    scopus 로고
    • Coordinate control of muscle cell survival by distinct insulin-like growth factor activated signaling pathways
    • Lawlor MA and Rotwein P (2000a) Coordinate control of muscle cell survival by distinct insulin-like growth factor activated signaling pathways. J Cell Biol 151:1131-1140.
    • (2000) J Cell Biol , vol.151 , pp. 1131-1140
    • Lawlor, M.A.1    Rotwein, P.2
  • 20
    • 0034462138 scopus 로고    scopus 로고
    • Insulin-like growth factor-mediated muscle cell survival: Central roles for Akt and cyclin-dependent kinase inhibitor p21
    • Lawlor MA and Rotwein P (2000b) Insulin-like growth factor-mediated muscle cell survival: central roles for Akt and cyclin-dependent kinase inhibitor p21. Mol Cell Biol 20:8983-8995.
    • (2000) Mol Cell Biol , vol.20 , pp. 8983-8995
    • Lawlor, M.A.1    Rotwein, P.2
  • 21
    • 0034711143 scopus 로고    scopus 로고
    • Inhibition of vascular smooth muscle cell proliferation by sodium salicylate mediated by up-regulation of p21(Waf1) and p27(Kip1)
    • Marra DE, Simoncini T, and Liao JK (2000) Inhibition of vascular smooth muscle cell proliferation by sodium salicylate mediated by up-regulation of p21(Waf1) and p27(Kip1). Circulation 102:2124-2130.
    • (2000) Circulation , vol.102 , pp. 2124-2130
    • Marra, D.E.1    Simoncini, T.2    Liao, J.K.3
  • 22
    • 0036853886 scopus 로고    scopus 로고
    • Hyperinsulinemia, glucose intolerance and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver
    • Miyake K, Ogawa W, Matsumoto M, Nakamura T, Sakaue H, and Kasuga M (2002) Hyperinsulinemia, glucose intolerance and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver. J Clin Investig 110:1483-1491.
    • (2002) J Clin Investig , vol.110 , pp. 1483-1491
    • Miyake, K.1    Ogawa, W.2    Matsumoto, M.3    Nakamura, T.4    Sakaue, H.5    Kasuga, M.6
  • 23
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, and Riccardi C (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139:271-279.
    • (1991) J Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 24
    • 0032537819 scopus 로고    scopus 로고
    • Signals from ras and rho GTPases interact to regulate expression of p21Waf/Cip1
    • Olson MF, Paterson HF, and Marshall CJ (1998) Signals from ras and rho GTPases interact to regulate expression of p21Waf/Cip1. Nature (Lond) 394:295-299.
    • (1998) Nature (Lond) , vol.394 , pp. 295-299
    • Olson, M.F.1    Paterson, H.F.2    Marshall, C.J.3
  • 28
    • 0035348486 scopus 로고    scopus 로고
    • Aspirin-induced activation of the NF-κB signaling pathway: A novel mechanism for aspirin-mediated apoptosis in colon cancer cells
    • Stark LA, Din FV, Zwacka RM, and Dunlop MG (2001) Aspirin-induced activation of the NF-κB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells. FASEB J 15:1273-1275.
    • (2001) FASEB J , vol.15 , pp. 1273-1275
    • Stark, L.A.1    Din, F.V.2    Zwacka, R.M.3    Dunlop, M.G.4
  • 29
    • 0036069555 scopus 로고    scopus 로고
    • Aspirin provides cyclin-dependent kinase 5-dependent protection against subsequent hypoxia/reoxygenation damage in culture
    • Vartiainen N, Keksa-Goldsteine V, Goldsteins G, and Koistinaho J (2002) Aspirin provides cyclin-dependent kinase 5-dependent protection against subsequent hypoxia/reoxygenation damage in culture. J Neurochem 82:329-335.
    • (2002) J Neurochem , vol.82 , pp. 329-335
    • Vartiainen, N.1    Keksa-Goldsteine, V.2    Goldsteins, G.3    Koistinaho, J.4
  • 33
    • 0032214980 scopus 로고    scopus 로고
    • Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase
    • Yu D, Jing T, Liu B, Yao J, Tan M, McDonnell TJ, and Hung MC (1998) Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase. Mol Cell 2:581-591.
    • (1998) Mol Cell , vol.2 , pp. 581-591
    • Yu, D.1    Jing, T.2    Liu, B.3    Yao, J.4    Tan, M.5    McDonnell, T.J.6    Hung, M.C.7
  • 35
    • 0033063017 scopus 로고    scopus 로고
    • Cell cycle block at G1-S or G2-M phase correlates with differentiation of caco-2 cells: Effect of constitutive insulin-like growth factor II expression
    • Zarrilli R, Pignata S, Apicella A, Di Popolo A, Memoli A, Ricchi P, Salzano S, and Acquaviva AM (1999) Cell cycle block at G1-S or G2-M phase correlates with differentiation of caco-2 cells: effect of constitutive insulin-like growth factor II expression. Gastroenterology 116:1358-1366.
    • (1999) Gastroenterology , vol.116 , pp. 1358-1366
    • Zarrilli, R.1    Pignata, S.2    Apicella, A.3    Di Popolo, A.4    Memoli, A.5    Ricchi, P.6    Salzano, S.7    Acquaviva, A.M.8
  • 36
    • 0028131791 scopus 로고
    • Expression of insulin-like growth factor (IGF)-II and IGF-I receptor during proliferation and differentiation of Caco-2 human colon carcinoma cells
    • Zarrilli R, Pignata S, Romano M, Gravina A, Casola S, Bruni CB, and Acquaviva AM (1994) Expression of insulin-like growth factor (IGF)-II and IGF-I receptor during proliferation and differentiation of Caco-2 human colon carcinoma cells. Cell Growth Differ 5:1085-1091.
    • (1994) Cell Growth Differ , vol.5 , pp. 1085-1091
    • Zarrilli, R.1    Pignata, S.2    Romano, M.3    Gravina, A.4    Casola, S.5    Bruni, C.B.6    Acquaviva, A.M.7
  • 37
    • 0029921059 scopus 로고    scopus 로고
    • Constitutive insulin-like growth factor-II expression interferes with the enterocyte-like differentiation of Caco-2 cells
    • Zarrilli R, Romano M, Pignata S, Casola S, Bruni CB, and Acquaviva AM (1996) Constitutive insulin-like growth factor-II expression interferes with the enterocyte-like differentiation of Caco-2 cells. J Biol Chem 271:8108-8114.
    • (1996) J Biol Chem , vol.271 , pp. 8108-8114
    • Zarrilli, R.1    Romano, M.2    Pignata, S.3    Casola, S.4    Bruni, C.B.5    Acquaviva, A.M.6
  • 38
    • 0034745353 scopus 로고    scopus 로고
    • Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neuoverexpressing cells
    • Zhou BP, Liao Y, Xia W, Spohn B, Lee MH, and Hung MC (2001a) Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neuoverexpressing cells. Nat Cell Biol 3:245-252.
    • (2001) Nat Cell Biol , vol.3 , pp. 245-252
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Spohn, B.4    Lee, M.H.5    Hung, M.C.6
  • 39
    • 0035736487 scopus 로고    scopus 로고
    • HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
    • Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, and Hung MC (2001b) HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat Cell Biol 3:973-982.
    • (2001) Nat Cell Biol , vol.3 , pp. 973-982
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Zou, Y.4    Spohn, B.5    Hung, M.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.