Human-yeast chimeric repair protein protects mammalian cells against alkylating agents: Enhancement of MGMT protection

Cancer Gene Therapy

Volumn 10, Issue 8, 2003, Pages 603-610

  Roth, Timothy J ^a   Xu, Yi ^a   Luo, Meihua ^a   Kelley, Mark R ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apn1; Base excision repair; MGMT; Translational

Indexed keywords

ALKYLATING AGENT; APN1 PROTEIN; CARMUSTINE; CHIMERIC PROTEIN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; FUNGAL PROTEIN; HYBRID PROTEIN; MESYLIC ACID; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE APN1 FUSION PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW SUPPRESSION; CANCER COMBINATION CHEMOTHERAPY; CELL PROTECTION; CYTOTOXICITY; DNA REPAIR; ENZYME ACTIVITY; EXCISION REPAIR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN ENGINEERING;

ALKYLATING AGENTS; CARMUSTINE; CELL SURVIVAL; CYTOPROTECTION; DNA REPAIR; ENDODEOXYRIBONUCLEASES; HUMANS; K562 CELLS; METHYL METHANESULFONATE; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS;

MAMMALIA;

EID: 0042733397     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700605     Document Type: Article

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