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Volumn 312, Issue 1, 2003, Pages 245-253

Hepatitis C virus core protein expression leads to biphasic regulation of the p21 cdk inhibitor and modulation of hepatocyte cell cycle

Author keywords

Biphasic; cdk2; Cell cycle; Core protein; HCV; p21

Indexed keywords

CDK2 DEPENDENT KINASE; CORE PROTEIN; ENZYME; PROTEIN CDK INHIBITOR; PROTEIN INHIBITOR; PROTEIN P21; UNCLASSIFIED DRUG;

EID: 0042668538     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0042-6822(03)00209-5     Document Type: Article
Times cited : (27)

References (40)
  • 2
    • 0034818446 scopus 로고    scopus 로고
    • Post-translational modifications and activation of p53 by genotoxic stresses
    • Appella E., Anderson C.W. Post-translational modifications and activation of p53 by genotoxic stresses. Eur. J. Biochem. 268:2001;2764-2772.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 2764-2772
    • Appella, E.1    Anderson, C.W.2
  • 4
    • 0031901556 scopus 로고    scopus 로고
    • Hepatitis C virus core from two different genotypes has an oncogenic potential but is not sufficient for transforming primary rat embryo fibroblasts in cooperation with the H-ras oncogene
    • Chang J., Yang S.H., Cho Y.G., Hwang S.B., Hahn Y.S., Sung Y.C. Hepatitis C virus core from two different genotypes has an oncogenic potential but is not sufficient for transforming primary rat embryo fibroblasts in cooperation with the H-ras oncogene. J. Virol. 72:1998;3060-3065.
    • (1998) J. Virol. , vol.72 , pp. 3060-3065
    • Chang, J.1    Yang, S.H.2    Cho, Y.G.3    Hwang, S.B.4    Hahn, Y.S.5    Sung, Y.C.6
  • 5
    • 0035809057 scopus 로고    scopus 로고
    • HCV core protein modulates Rb pathway through pRb down-regulation and E2F-1 up-regulation
    • Cho J., Baek W., Yang S., Chang J., Sung Y.C., Suh M. HCV core protein modulates Rb pathway through pRb down-regulation and E2F-1 up-regulation. Biochim. Biophys. Acta. 1538:2001;59-66.
    • (2001) Biochim. Biophys. Acta , vol.1538 , pp. 59-66
    • Cho, J.1    Baek, W.2    Yang, S.3    Chang, J.4    Sung, Y.C.5    Suh, M.6
  • 6
    • 0035042905 scopus 로고    scopus 로고
    • Hepatitis C virus core protein promotes cell proliferation through the upregulation of cyclin E expression levels
    • Cho J.W., Baek W.K., Suh S.I., Yang S.H., Chang J., Sung Y.C., Suh M.H. Hepatitis C virus core protein promotes cell proliferation through the upregulation of cyclin E expression levels. Liver. 21:2001;137-142.
    • (2001) Liver , vol.21 , pp. 137-142
    • Cho, J.W.1    Baek, W.K.2    Suh, S.I.3    Yang, S.H.4    Chang, J.5    Sung, Y.C.6    Suh, M.H.7
  • 7
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from blood-borne non-A, non-B viral hepatitis genome
    • Choo Q.L., Kuo G., Weiner A.J., Overby L.R., Bradley D.W., Houghton M. Isolation of a cDNA clone derived from blood-borne non-A, non-B viral hepatitis genome. Science. 244:1989;359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 8
    • 0030770835 scopus 로고    scopus 로고
    • Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
    • Chuang L.S., Ian H.I., Koh T.W., Ng H.H., Xu G., Li B.F. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science. 277:1997;1996-2000.
    • (1997) Science , vol.277 , pp. 1996-2000
    • Chuang, L.S.1    Ian, H.I.2    Koh, T.W.3    Ng, H.H.4    Xu, G.5    Li, B.F.6
  • 9
    • 0033454740 scopus 로고    scopus 로고
    • Transforming growth factor beta from multiple myeloma cells inhibits proliferation and IL-2 responsiveness in T lymphocytes
    • Cook G., Campbell J.D., Carr C.E., Boyd K.S., Franklin I.M. Transforming growth factor beta from multiple myeloma cells inhibits proliferation and IL-2 responsiveness in T lymphocytes. J. Leukoc. Biol. 66:1999;981-988.
    • (1999) J. Leukoc. Biol. , vol.66 , pp. 981-988
    • Cook, G.1    Campbell, J.D.2    Carr, C.E.3    Boyd, K.S.4    Franklin, I.M.5
  • 10
    • 0029073142 scopus 로고
    • Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
    • Datto M.B., Li Y., Panus J.F., Howe D.J., Xiong Y., Wang X.F. Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc. Natl. Acad. Sci. USA. 92:1995;5545-5549.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5545-5549
    • Datto, M.B.1    Li, Y.2    Panus, J.F.3    Howe, D.J.4    Xiong, Y.5    Wang, X.F.6
  • 11
    • 0034738420 scopus 로고    scopus 로고
    • P21(WAF1/Cip1): More than a break to the cell cycle?
    • Dotto G.P. p21(WAF1/Cip1) more than a break to the cell cycle? Biochim. Biophys. Acta. 1471:2000;M43-M56.
    • (2000) Biochim. Biophys. Acta , vol.1471
    • Dotto, G.P.1
  • 15
    • 0035813022 scopus 로고    scopus 로고
    • The repressive activity of hepatitis C virus core protein on the transcription of p21 (waf1) is regulated by protein kinase A-mediated phosphorylation
    • Jung E.Y., Lee M.N., Yang H.Y., Yu D., Jang K.L. The repressive activity of hepatitis C virus core protein on the transcription of p21 (waf1) is regulated by protein kinase A-mediated phosphorylation. Virus Res. 79:2001;109-115.
    • (2001) Virus Res. , vol.79 , pp. 109-115
    • Jung, E.Y.1    Lee, M.N.2    Yang, H.Y.3    Yu, D.4    Jang, K.L.5
  • 16
    • 0036061434 scopus 로고    scopus 로고
    • Conformational changes accompanying self-assembly of the hepatitis C virus core protein
    • Kunkel M., Watowich S.J. Conformational changes accompanying self-assembly of the hepatitis C virus core protein. Virology. 294:2002;239-245.
    • (2002) Virology , vol.294 , pp. 239-245
    • Kunkel, M.1    Watowich, S.J.2
  • 17
    • 0036713601 scopus 로고    scopus 로고
    • Hepatitis C virus core protein represses the p21 promoter through inhibition of a TGF-beta pathway
    • Lee M.N., Jung E.Y., Kwun H.J., Jun H.K., Yu D.Y., Choi Y.H., Jang K.L. Hepatitis C virus core protein represses the p21 promoter through inhibition of a TGF-beta pathway. J. Gen. Virol. 83 (Pt 9):2002;2145-2151.
    • (2002) J. Gen. Virol. , vol.83 , Issue.PART 9 , pp. 2145-2151
    • Lee, M.N.1    Jung, E.Y.2    Kwun, H.J.3    Jun, H.K.4    Yu, D.Y.5    Choi, Y.H.6    Jang, K.L.7
  • 18
    • 0028074603 scopus 로고
    • Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair
    • Li R., Waga S., Hannon G.J., Beach D., Stillman B. Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair. Nature. 371:1994;534-537.
    • (1994) Nature , vol.371 , pp. 534-537
    • Li, R.1    Waga, S.2    Hannon, G.J.3    Beach, D.4    Stillman, B.5
  • 19
    • 0028840840 scopus 로고
    • Differential subcellular localization of hepatitis C virus core gene products
    • Lo S.Y., Masiarz F., Hwang S.B., Lai M.M., Ou J.H. Differential subcellular localization of hepatitis C virus core gene products. Virology. 213:1995;455-461.
    • (1995) Virology , vol.213 , pp. 455-461
    • Lo, S.Y.1    Masiarz, F.2    Hwang, S.B.3    Lai, M.M.4    Ou, J.H.5
  • 20
    • 0033544419 scopus 로고    scopus 로고
    • Activation of p53 tumor suppressor by hepatitis C virus core protein
    • Lu W., Lo S.Y., Chen M., Wu K., Fung Y.K., Ou J.H. Activation of p53 tumor suppressor by hepatitis C virus core protein. Virology. 264:1999;134-141.
    • (1999) Virology , vol.264 , pp. 134-141
    • Lu, W.1    Lo, S.Y.2    Chen, M.3    Wu, K.4    Fung, Y.K.5    Ou, J.H.6
  • 23
    • 0036193744 scopus 로고    scopus 로고
    • Simian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle
    • Ndolo T., Dhillon N.K., Nguyen H., Guadalupe M., Mudryj M., Dandekar S. Simian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle. J. Virol. 76:2002;3587-3595.
    • (2002) J. Virol. , vol.76 , pp. 3587-3595
    • Ndolo, T.1    Dhillon, N.K.2    Nguyen, H.3    Guadalupe, M.4    Mudryj, M.5    Dandekar, S.6
  • 25
    • 0034602420 scopus 로고    scopus 로고
    • Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability
    • Otsuka M., Kato N., Lan K., Yoshida H., Kato J., Goto T., Shiratori Y., Omata M. Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability. J. Biol. Chem. 275:2000;34122-34130.
    • (2000) J. Biol. Chem. , vol.275 , pp. 34122-34130
    • Otsuka, M.1    Kato, N.2    Lan, K.3    Yoshida, H.4    Kato, J.5    Goto, T.6    Shiratori, Y.7    Omata, M.8
  • 26
    • 0030614504 scopus 로고    scopus 로고
    • Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
    • Perkins N.D., Felzien L.K., Betts J.C., Leung K., Beach D.H., Nabel G.J. Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science. 275:1997;523-527.
    • (1997) Science , vol.275 , pp. 523-527
    • Perkins, N.D.1    Felzien, L.K.2    Betts, J.C.3    Leung, K.4    Beach, D.H.5    Nabel, G.J.6
  • 27
    • 8944262349 scopus 로고    scopus 로고
    • Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype
    • Ray R.B., Lagging L.M., Meyer K., Ray R. Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. J. Virol. 70:1996;4438-4443.
    • (1996) J. Virol. , vol.70 , pp. 4438-4443
    • Ray, R.B.1    Lagging, L.M.2    Meyer, K.3    Ray, R.4
  • 28
    • 0029114785 scopus 로고
    • Transcriptional regulation of cellular and viral promoters by the hepatitis C virus core protein
    • Ray R.B., Lagging L.M., Meyer K., Steele R., Ray R. Transcriptional regulation of cellular and viral promoters by the hepatitis C virus core protein. Virus Res. 37:1995;209-220.
    • (1995) Virus Res. , vol.37 , pp. 209-220
    • Ray, R.B.1    Lagging, L.M.2    Meyer, K.3    Steele, R.4    Ray, R.5
  • 29
    • 0035928765 scopus 로고    scopus 로고
    • Hepatitis C virus core protein: Intriguing properties and functional relevance
    • Ray R.B., Ray R. Hepatitis C virus core protein intriguing properties and functional relevance . FEMS Microbiol. Lett. 202:2001;149-156.
    • (2001) FEMS Microbiol. Lett. , vol.202 , pp. 149-156
    • Ray, R.B.1    Ray, R.2
  • 30
    • 0032570876 scopus 로고    scopus 로고
    • Hepatitis C virus core protein represses 21WAF1/Cip1/Sid1 promoter activity
    • Ray R.B., Steele R., Meyer K., Ray R. Hepatitis C virus core protein represses 21WAF1/Cip1/Sid1 promoter activity. Gene. 208:1998;331-336.
    • (1998) Gene , vol.208 , pp. 331-336
    • Ray, R.B.1    Steele, R.2    Meyer, K.3    Ray, R.4
  • 33
    • 0031968822 scopus 로고    scopus 로고
    • Cell cycle dysregulation by human cytomegalovirus: Influence of the cell cycle phase at the time of infection and effects on cyclin transcription
    • Salvant B.S., Fortunato E.A., Spector D.H. Cell cycle dysregulation by human cytomegalovirus influence of the cell cycle phase at the time of infection and effects on cyclin transcription . J. Virol. 72:1998;3729-3741.
    • (1998) J. Virol. , vol.72 , pp. 3729-3741
    • Salvant, B.S.1    Fortunato, E.A.2    Spector, D.H.3
  • 34
    • 0035866327 scopus 로고    scopus 로고
    • Ubiquitin-mediated degradation of hepatitis C virus core protein is regulated by processing at its carboxyl terminus
    • Suzuki R., Tamura K., Li J., Ishii K., Matsuura Y., Miyamura T., Suzuki T. Ubiquitin-mediated degradation of hepatitis C virus core protein is regulated by processing at its carboxyl terminus. Virology. 280:2001;301-309.
    • (2001) Virology , vol.280 , pp. 301-309
    • Suzuki, R.1    Tamura, K.2    Li, J.3    Ishii, K.4    Matsuura, Y.5    Miyamura, T.6    Suzuki, T.7
  • 35
    • 0028109022 scopus 로고
    • Pathology of hepatitis C
    • Uchida T. Pathology of hepatitis C. Intervirology. 37:1994;126-132.
    • (1994) Intervirology , vol.37 , pp. 126-132
    • Uchida, T.1
  • 36
    • 0036290134 scopus 로고    scopus 로고
    • Subcellular localization of HCV core protein regulates its ability for p53 activation and p21 suppression
    • Yamanaka T., Kodama T., Doi T. Subcellular localization of HCV core protein regulates its ability for p53 activation and p21 suppression. Biochem. Biophys. Res. Commun. 294:2002;528-534.
    • (2002) Biochem. Biophys. Res. Commun. , vol.294 , pp. 528-534
    • Yamanaka, T.1    Kodama, T.2    Doi, T.3
  • 37
    • 0036289002 scopus 로고    scopus 로고
    • Innate form of HCV core protein plays an important role in the localization and the function of HCV core protein
    • Yamanaka T., Uchida M., Doi T. Innate form of HCV core protein plays an important role in the localization and the function of HCV core protein. Biochem. Biophys. Res. Commun. 294:2002;528-534.
    • (2002) Biochem. Biophys. Res. Commun. , vol.294 , pp. 528-534
    • Yamanaka, T.1    Uchida, M.2    Doi, T.3
  • 40
    • 0027440552 scopus 로고
    • Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes
    • Zhang H., Xiong Y., Beach D. Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes. Mol. Biol. Cell. 4:1993;897-906.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 897-906
    • Zhang, H.1    Xiong, Y.2    Beach, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.