메뉴 건너뛰기




Volumn 85, Issue 2-5, 2003, Pages 329-335

Neuroactive steroids: New biomarkers of cognitive aging

Author keywords

Cognitive aging; Neuroactive steroids; Pregnenolone sulfate

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; 3ALPHA HYDROXYSTEROID DEHYDROGENASE; 3BETA HYDROXY 5BETA PREGNAN 20 ONE SULFATE; ALCOHOL; BIOLOGICAL MARKER; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CHOLESTEROL SIDE CHAIN CLEAVAGE CYTOCHROME P450; HYDROXYSTEROID SULFOTRANSFERASE; PREGNENOLONE; PREGNENOLONE DERIVATIVE; PREGNENOLONE SULFATE; SCOPOLAMINE; STEROID; STEROID SULFATASE SULFOHYDROLASE; UNCLASSIFIED DRUG;

EID: 0042477744     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(03)00227-9     Document Type: Conference Paper
Times cited : (21)

References (58)
  • 1
    • 0028174238 scopus 로고
    • Ethanol modulation of the gamma-aminobutyric acidA- and glycine-activated Cl-current in cultured mouse neurons
    • Aguayo L.G., Pancetti F.C. Ethanol modulation of the gamma-aminobutyric acidA- and glycine-activated Cl-current in cultured mouse neurons. J. Pharmacol. Exp. Ther. 270(1):1994;61-69.
    • (1994) J. Pharmacol. Exp. Ther. , vol.270 , Issue.1 , pp. 61-69
    • Aguayo, L.G.1    Pancetti, F.C.2
  • 2
    • 0035923595 scopus 로고    scopus 로고
    • The synthetic enantiomer of pregnenolone sulfate is very active on memory in rats and mice, even more so than its physiological neurosteroid counterpart: Distinct mechanisms?
    • Akwa Y., Ladurelle N., Covey D.F., Baulieu E.-E. The synthetic enantiomer of pregnenolone sulfate is very active on memory in rats and mice, even more so than its physiological neurosteroid counterpart: distinct mechanisms? Proc. Natl. Acad. Sci. U.S.A. 98(24):2001;14033-14037.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , Issue.24 , pp. 14033-14037
    • Akwa, Y.1    Ladurelle, N.2    Covey, D.F.3    Baulieu, E.-E.4
  • 3
    • 77956970200 scopus 로고    scopus 로고
    • Pharmacology of Alzheimer's disease
    • G.P. Ellis, D.K. Luscombe (Eds.), Elsevier, New York
    • H. Allain, D. Bentué-Ferrer, S. Belliard, C. Dérousné, Pharmacology of Alzheimer's disease, in: G.P. Ellis, D.K. Luscombe (Eds.), Progress in Medical Chemistry, vol. 34, Elsevier, New York, 1997, pp. 1-67.
    • (1997) Progress in Medical Chemistry , vol.34 , pp. 1-67
    • Allain, H.1    Bentué-Ferrer, D.2    Belliard, S.3    Dérousné, C.4
  • 4
    • 0035233066 scopus 로고    scopus 로고
    • Neurosteroid analysis
    • G. Biggio, R.H. Purdy (Eds.), Academic Press, San Diego, CA, USA
    • A.A. Alomary, R.L. Fitzgerald, R.H. Purdy, Neurosteroid analysis, in: G. Biggio, R.H. Purdy (Eds.), Neurosteroids and Brain Function, vol. 46, Academic Press, San Diego, CA, USA, 2001, pp. 98-112.
    • (2001) Neurosteroids and Brain Function , vol.46 , pp. 98-112
    • Alomary, A.A.1    Fitzgerald, R.L.2    Purdy, R.H.3
  • 5
    • 0027201969 scopus 로고
    • Facilitation of memory storage by the acetylcholine M2 muscarinic receptor antagonist AF-DX 116
    • Baratti C.M., Opezzo J.W., Kopf S.R. Facilitation of memory storage by the acetylcholine M2 muscarinic receptor antagonist AF-DX 116. Behav. Neural Biol. 60(1):1993;69-74.
    • (1993) Behav. Neural Biol. , vol.60 , Issue.1 , pp. 69-74
    • Baratti, C.M.1    Opezzo, J.W.2    Kopf, S.R.3
  • 6
    • 0001178207 scopus 로고
    • Animal models of age-related cognitive deficits
    • F. Boller, J. Grafman (Eds.), Elsevier, Amsterdam
    • C.A. Barnes, Animal models of age-related cognitive deficits, in: F. Boller, J. Grafman (Eds.), Handbook of Neuropsychology, Elsevier, Amsterdam, 1990, pp. 169-196.
    • (1990) Handbook of Neuropsychology , pp. 169-196
    • Barnes, C.A.1
  • 7
    • 0002349845 scopus 로고
    • Steroid hormones in the brain: several mechanisms?
    • K. Fuxe, J.A. Gustafsson, L. Weterberg (Eds.), Pergamon Press, Oxford
    • E.-E. Baulieu, Steroid hormones in the brain: several mechanisms?, in: K. Fuxe, J.A. Gustafsson, L. Weterberg (Eds.), Steroid Hormone Regulation of the Brain, Pergamon Press, Oxford, 1981, pp. 3-14.
    • (1981) Steroid Hormone Regulation of the Brain , pp. 3-14
    • Baulieu, E.-E.1
  • 8
    • 0032448780 scopus 로고    scopus 로고
    • Neurosteroids: A novel function of the brain
    • (review)
    • Baulieu E.-E. Neurosteroids: a novel function of the brain. Psychoneuroendocrinology. 23(8):1998;963-987. (review).
    • (1998) Psychoneuroendocrinology , vol.23 , Issue.8 , pp. 963-987
    • Baulieu, E.-E.1
  • 9
    • 0029940447 scopus 로고    scopus 로고
    • Neurobiological substrates of behavioral decline: Models and data analytic strategies for individual differences in aging
    • Baxter M.G., Gallagher M. Neurobiological substrates of behavioral decline: models and data analytic strategies for individual differences in aging. Neurobiol. Aging. 17(3):1996;491-495.
    • (1996) Neurobiol. Aging , vol.17 , Issue.3 , pp. 491-495
    • Baxter, M.G.1    Gallagher, M.2
  • 10
    • 0027155274 scopus 로고
    • Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons
    • Bowlby M.R. Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons. Mol. Pharmacol. 43(5):1993;813-819.
    • (1993) Mol. Pharmacol. , vol.43 , Issue.5 , pp. 813-819
    • Bowlby, M.R.1
  • 11
    • 0029067030 scopus 로고
    • Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats
    • Cheney D.L., Uzunov D., Costa E., Guidotti A. Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats. J. Neurosci. 15(6):1995;4641-4650.
    • (1995) J. Neurosci. , vol.15 , Issue.6 , pp. 4641-4650
    • Cheney, D.L.1    Uzunov, D.2    Costa, E.3    Guidotti, A.4
  • 12
    • 0029145499 scopus 로고
    • Pregnenolone sulfate antagonizes dizocilpine amnesia: Role for allopregnanolone
    • Cheney D.L., Uzunov D., Guidotti A. Pregnenolone sulfate antagonizes dizocilpine amnesia: role for allopregnanolone. NeuroReport. 6(12):1995;1697-1700.
    • (1995) NeuroReport , vol.6 , Issue.12 , pp. 1697-1700
    • Cheney, D.L.1    Uzunov, D.2    Guidotti, A.3
  • 13
    • 0026316550 scopus 로고
    • Divergence of biological and chronological aging: Evidence from rodent studies
    • (review)
    • Collier T.J., Coleman P.D. Divergence of biological and chronological aging: evidence from rodent studies. Neurobiol. Aging. 12(6):1991;685-693. (review).
    • (1991) Neurobiol. Aging , vol.12 , Issue.6 , pp. 685-693
    • Collier, T.J.1    Coleman, P.D.2
  • 15
    • 0033979932 scopus 로고    scopus 로고
    • Pregnenolone sulfate increases hippocampal acetylcholine release and spatial recognition
    • Darnaudéry M., Koehl M., Piazza P.-V., Le Moal M., Mayo W. Pregnenolone sulfate increases hippocampal acetylcholine release and spatial recognition. Brain Res. 852(1):2000;173-179.
    • (2000) Brain Res. , vol.852 , Issue.1 , pp. 173-179
    • Darnaudéry, M.1    Koehl, M.2    Piazza, P.-V.3    Le Moal, M.4    Mayo, W.5
  • 17
    • 0030636350 scopus 로고    scopus 로고
    • Central cholinergic systems and cognition
    • Everitt B.J., Robbins T.W. Central cholinergic systems and cognition. Annu. Rev. Psychol. 48:1997;649-684.
    • (1997) Annu. Rev. Psychol. , vol.48 , pp. 649-684
    • Everitt, B.J.1    Robbins, T.W.2
  • 18
    • 0028853687 scopus 로고
    • Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures: The amygdala is by far the most sensitive
    • Flood J.F., Morley J.E., Roberts E. Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures: the amygdala is by far the most sensitive. Proc. Natl. Acad. Sci. U.S.A. 92(23):1995;10806-10810.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , Issue.23 , pp. 10806-10810
    • Flood, J.F.1    Morley, J.E.2    Roberts, E.3
  • 19
    • 0028243901 scopus 로고
    • Glutamatergic regulation of acetylcholine output in different brain regions: A microdialysis study in the rat
    • Giovannini M.G., Camilli F., Mundula A., Pepeu G. Glutamatergic regulation of acetylcholine output in different brain regions: a microdialysis study in the rat. Neurochem. Int. 25(1):1994a;23-26.
    • (1994) Neurochem. Int. , vol.25 , Issue.1 , pp. 23-26
    • Giovannini, M.G.1    Camilli, F.2    Mundula, A.3    Pepeu, G.4
  • 20
    • 0030851886 scopus 로고    scopus 로고
    • Glutamatergic modulation of cortical acetylcholine release in the rat: A combined in vivo microdialysis
    • Giovannini M.G., Giovannelli L., Bianchi L., Kalfin R., Pepeu G. Glutamatergic modulation of cortical acetylcholine release in the rat: a combined in vivo microdialysis. Eur. J. Neurosci. 9(8):1997;1678-1689.
    • (1997) Eur. J. Neurosci. , vol.9 , Issue.8 , pp. 1678-1689
    • Giovannini, M.G.1    Giovannelli, L.2    Bianchi, L.3    Kalfin, R.4    Pepeu, G.5
  • 21
    • 0028218273 scopus 로고
    • NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: A microdialysis study
    • Giovannini M.G., Mutolo D., Bianchi L., Michelassi A., Pepeu G. NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study. J. Neurosci. 14(3):1994;1358-1365.
    • (1994) J. Neurosci. , vol.14 , Issue.3 , pp. 1358-1365
    • Giovannini, M.G.1    Mutolo, D.2    Bianchi, L.3    Michelassi, A.4    Pepeu, G.5
  • 22
    • 0027418083 scopus 로고
    • Codistribution of GABA - With acetylcholine - Synthesizing neurons in the basal forebrain of the rat
    • Gritti I., Mainville L., Jones B.E. Codistribution of GABA - with acetylcholine - synthesizing neurons in the basal forebrain of the rat. J. Comp. Neurol. 329(4):1993;438-457.
    • (1993) J. Comp. Neurol. , vol.329 , Issue.4 , pp. 438-457
    • Gritti, I.1    Mainville, L.2    Jones, B.E.3
  • 23
    • 0023175459 scopus 로고
    • Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex
    • Harrison N.L., Majewska M.D., Harrington J.W., Barker J.L. Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex. J. Pharmacol. Exp. Ther. 241(1):1987;346-353.
    • (1987) J. Pharmacol. Exp. Ther. , vol.241 , Issue.1 , pp. 346-353
    • Harrison, N.L.1    Majewska, M.D.2    Harrington, J.W.3    Barker, J.L.4
  • 26
    • 0034650302 scopus 로고    scopus 로고
    • Profiling neurosteroids in cerebrospinal fluids and plasma by gas chromatography/electron capture negative chemical ionization mass spectrometry
    • Kim Y.-S., Zhang H., Kim H.-Y. Profiling neurosteroids in cerebrospinal fluids and plasma by gas chromatography/electron capture negative chemical ionization mass spectrometry. Anal. Biochem. 277(2):2000;187-195.
    • (2000) Anal. Biochem. , vol.277 , Issue.2 , pp. 187-195
    • Kim, Y.-S.1    Zhang, H.2    Kim, H.-Y.3
  • 27
    • 0034913104 scopus 로고    scopus 로고
    • Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis
    • Kimoto T., Tsurugizawa T., Ohta Y., Makino J., Tamura H., Hojo Y., Takata N., Kawato S. Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis. Endocrinology. 142(8):2001;3578-3589.
    • (2001) Endocrinology , vol.142 , Issue.8 , pp. 3578-3589
    • Kimoto, T.1    Tsurugizawa, T.2    Ohta, Y.3    Makino, J.4    Tamura, H.5    Hojo, Y.6    Takata, N.7    Kawato, S.8
  • 30
    • 0028032491 scopus 로고
    • The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task
    • Mathis C., Paul S.M., Crawley J.N. The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task. Psychopharmacology. 116(2):1994;201-206.
    • (1994) Psychopharmacology , vol.116 , Issue.2 , pp. 201-206
    • Mathis, C.1    Paul, S.M.2    Crawley, J.N.3
  • 31
    • 0030445549 scopus 로고    scopus 로고
    • The neurosteroid pregnenolone sulfate blocks deficits induced by a competitive NMDA antagonist in active avoidance and lever-press learning tasks in mice
    • Mathis C., Vogel E., Cagniard B., Criscuolo F., Ungerer A. The neurosteroid pregnenolone sulfate blocks deficits induced by a competitive NMDA antagonist in active avoidance and lever-press learning tasks in mice. Neuropharmacology. 35(8):1996;1057-1064.
    • (1996) Neuropharmacology , vol.35 , Issue.8 , pp. 1057-1064
    • Mathis, C.1    Vogel, E.2    Cagniard, B.3    Criscuolo, F.4    Ungerer, A.5
  • 32
    • 0035660075 scopus 로고    scopus 로고
    • The interaction between neuroactive steroids and the sigma1 receptor function: Behavioral consequences and therapeutic opportunities
    • Maurice T., Urani A., Phan V.L., Romieu P. The interaction between neuroactive steroids and the sigma1 receptor function: behavioral consequences and therapeutic opportunities. Brain Res. Brain Res. Rev. 37(1-3):2001;116-132.
    • (2001) Brain Res. Brain Res. Rev. , vol.37 , Issue.1-3 , pp. 116-132
    • Maurice, T.1    Urani, A.2    Phan, V.L.3    Romieu, P.4
  • 33
    • 0037047305 scopus 로고    scopus 로고
    • Neurosteroids enhance spontaneous glutamate release in hippocampal neurons. Possible role of metabotropic sigma1-like receptors
    • Meyer D.A., Carta M., Partridge L.D., Covey D.F., Valenzuela C.F. Neurosteroids enhance spontaneous glutamate release in hippocampal neurons. Possible role of metabotropic sigma1-like receptors. J. Biol. Chem. 277(32):2002;28725-28732.
    • (2002) J. Biol. Chem. , vol.277 , Issue.32 , pp. 28725-28732
    • Meyer, D.A.1    Carta, M.2    Partridge, L.D.3    Covey, D.F.4    Valenzuela, C.F.5
  • 34
    • 0027394538 scopus 로고
    • Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat
    • Mayo W., Dellu F., Robel P., Cherkaoui J., Le Moal M., Baulieu E.-E., Simon H. Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat. Brain Res. 607(1-2):1993;324-328.
    • (1993) Brain Res. , vol.607 , Issue.1-2 , pp. 324-328
    • Mayo, W.1    Dellu, F.2    Robel, P.3    Cherkaoui, J.4    Le Moal, M.5    Baulieu, E.-E.6    Simon, H.7
  • 36
    • 0036752591 scopus 로고    scopus 로고
    • Sex, stress and the hippocampus: Allostasis, allostatic load and the aging process
    • McEwen B.S. Sex, stress and the hippocampus: allostasis, allostatic load and the aging process. Neurobiol. Aging. 23(5):2002;921-939.
    • (2002) Neurobiol. Aging , vol.23 , Issue.5 , pp. 921-939
    • McEwen, B.S.1
  • 37
    • 0031081205 scopus 로고    scopus 로고
    • Interaction of neuromodulatory systems in modulating memory storage
    • McGaugh J.L., Cahill L. Interaction of neuromodulatory systems in modulating memory storage. Behav. Brain Res. 83(1-2):1997;31-38.
    • (1997) Behav. Brain Res. , vol.83 , Issue.1-2 , pp. 31-38
    • McGaugh, J.L.1    Cahill, L.2
  • 38
    • 0029670384 scopus 로고    scopus 로고
    • Neurosteroids block the memory-impairing effects of ethanol in mice
    • Melchior C.L., Ritzmann R.F. Neurosteroids block the memory-impairing effects of ethanol in mice. Pharm. Biochem. Behav. 53(1):1996;51-56.
    • (1996) Pharm. Biochem. Behav. , vol.53 , Issue.1 , pp. 51-56
    • Melchior, C.L.1    Ritzmann, R.F.2
  • 39
    • 0036133869 scopus 로고    scopus 로고
    • Neurosteroids: Biochemistry and clinical significance
    • Mellon S.H., Griffin L.D. Neurosteroids: biochemistry and clinical significance. Trends Endocrinol. Metab. 13(1):2002;35-43.
    • (2002) Trends Endocrinol. Metab. , vol.13 , Issue.1 , pp. 35-43
    • Mellon, S.H.1    Griffin, L.D.2
  • 41
    • 0032474840 scopus 로고    scopus 로고
    • A receptor pharmacology of enantiomers of dehydroepiandrosterone sulfate, pregnenolone sulfate, and (3α,5β)-3-hydroxypregnan-20-one sulfate
    • A receptor pharmacology of enantiomers of dehydroepiandrosterone sulfate, pregnenolone sulfate, and (3α,5β)-3-hydroxypregnan-20-one sulfate. J. Med. Chem. 41(14):1998;2604-2613.
    • (1998) J. Med. Chem. , vol.41 , Issue.14 , pp. 2604-2613
    • Nilsson, K.R.1    F Zorumski, C.2    Covey, D.F.3
  • 42
    • 0033614716 scopus 로고    scopus 로고
    • Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites
    • Park-Chung M., Malayev A., Purdy R.H., Gibbs T.T., Farb D.H. Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites. Brain Res. 830(1):1999;72-87.
    • (1999) Brain Res. , vol.830 , Issue.1 , pp. 72-87
    • Park-Chung, M.1    Malayev, A.2    Purdy, R.H.3    Gibbs, T.T.4    Farb, D.H.5
  • 43
    • 0031467726 scopus 로고    scopus 로고
    • Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids
    • Park-Chung M., Wu F.-S., Purdy R.H., Malayev A.A., Gibbs T.T., Farb D.H. Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids. Mol. Pharmacol. 52(6):1997;1113-1123.
    • (1997) Mol. Pharmacol. , vol.52 , Issue.6 , pp. 1113-1123
    • Park-Chung, M.1    Wu, F.-S.2    Purdy, R.H.3    Malayev, A.A.4    Gibbs, T.T.5    Farb, D.H.6
  • 44
    • 0026579057 scopus 로고
    • Neuroactive steroids
    • Paul S.M., Purdy R.H. Neuroactive steroids. FASEB J. 6(6):1992;2311-2322.
    • (1992) FASEB J. , vol.6 , Issue.6 , pp. 2311-2322
    • Paul, S.M.1    Purdy, R.H.2
  • 45
    • 0026682533 scopus 로고
    • Individual differences in the cognitive and neurobiological consequences of normal aging
    • Rapp P.R., Amaral D.G. Individual differences in the cognitive and neurobiological consequences of normal aging. Trends Neurosci. 15(9):1992;340-345.
    • (1992) Trends Neurosci. , vol.15 , Issue.9 , pp. 340-345
    • Rapp, P.R.1    Amaral, D.G.2
  • 47
    • 0028244499 scopus 로고
    • Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizolcipine amnesia: Putative role for allopregnanolone
    • Romeo E., Cheney D.L., Zivkovic I., Costa E., Guidotti A. Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizolcipine amnesia: putative role for allopregnanolone. J. Pharm. Exp. Ther. 270(1):1994;89-96.
    • (1994) J. Pharm. Exp. Ther. , vol.270 , Issue.1 , pp. 89-96
    • Romeo, E.1    Cheney, D.L.2    Zivkovic, I.3    Costa, E.4    Guidotti, A.5
  • 48
    • 0034164416 scopus 로고    scopus 로고
    • Glucocorticoids and the regulation of memory consolidation
    • Roozendaal B. Glucocorticoids and the regulation of memory consolidation. Psychoneuroendocrinology. 25(3):2000;213-238.
    • (2000) Psychoneuroendocrinology , vol.25 , Issue.3 , pp. 213-238
    • Roozendaal, B.1
  • 49
    • 0007489859 scopus 로고
    • Old rats: an animal model for senile dementia
    • A. Bès (Ed.), John Libbey Eurotext, London
    • E. Schuurman, D.G. Horvath, Jr. Spencer, J. Traber, Old rats: an animal model for senile dementia, in: A. Bès (Ed.), Senile Dementias: Early Detection, John Libbey Eurotext, London, 1986, pp. 624-630.
    • (1986) Senile Dementias: Early Detection , pp. 624-630
    • Schuurman, E.1    Horvath D.G., Jr.2    Spencer J. Traber3
  • 50
    • 0033993064 scopus 로고    scopus 로고
    • Studies on neurosteroids. X. Determination of pregnenolone and dehydroepiandrosterone in rat brains using gas chromatography-mass spectrometry-mass spectrometry
    • Shimada K., Yago K.J. Studies on neurosteroids. X. Determination of pregnenolone and dehydroepiandrosterone in rat brains using gas chromatography-mass spectrometry-mass spectrometry. Chromatogr. Sci. 38(1):2000;6-10.
    • (2000) Chromatogr. Sci. , vol.38 , Issue.1 , pp. 6-10
    • Shimada, K.1    Yago, K.J.2
  • 51
    • 0035206892 scopus 로고    scopus 로고
    • Neurosteroid metabolism in the human brain
    • Stoffel-Wagner B. Neurosteroid metabolism in the human brain. Eur. J. Endocrinol. 145(6):2001;669-679.
    • (2001) Eur. J. Endocrinol. , vol.145 , Issue.6 , pp. 669-679
    • Stoffel-Wagner, B.1
  • 53
    • 0029970863 scopus 로고    scopus 로고
    • Fluoxetine-elicited changes in brain neurosteroid content measured by negative mass fragmentography
    • Uzunov D.P., Cooper T.B., Costa E., Guidotti A. Fluoxetine-elicited changes in brain neurosteroid content measured by negative mass fragmentography. Proc. Natl. Acad. Sci. U.S.A. 93(22):1996;12599-12604.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , Issue.22 , pp. 12599-12604
    • Uzunov, D.P.1    Cooper, T.B.2    Costa, E.3    Guidotti, A.4
  • 55
    • 0034544581 scopus 로고    scopus 로고
    • Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry
    • Vallée M., Rivera J.D., Koob G.F., Purdy R.H., Fitzgerald R.L. Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry. Anal. Biochem. 287(1):2000;153-166.
    • (2000) Anal. Biochem. , vol.287 , Issue.1 , pp. 153-166
    • Vallée, M.1    Rivera, J.D.2    Koob, G.F.3    Purdy, R.H.4    Fitzgerald, R.L.5
  • 56
    • 0035783431 scopus 로고    scopus 로고
    • Steroid structure and pharmacological properties determine the anti-amnesic effects of pregnenolone sulphate in the passive avoidance task in rats
    • Vallée M., Shen W., Heinrichs S.C., Zorumski C.F., Covey D.F., Koob G.F., Purdy R.H. Steroid structure and pharmacological properties determine the anti-amnesic effects of pregnenolone sulphate in the passive avoidance task in rats. Eur. J. Neurosci. 14(12):2001;2003-2010.
    • (2001) Eur. J. Neurosci. , vol.14 , Issue.12 , pp. 2003-2010
    • Vallée, M.1    Shen, W.2    Heinrichs, S.C.3    Zorumski, C.F.4    Covey, D.F.5    Koob, G.F.6    Purdy, R.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.