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Volumn 75, Issue 1, 2003, Pages 1-6

Toxicogenetics: Applications and opportunities

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ALLERGEN; CARBAMAZEPINE; DIAZEPAM; ENVIRONMENTAL CHEMICAL; OMEPRAZOLE; RNA DIRECTED DNA POLYMERASE INHIBITOR; WARFARIN;

EID: 0042383038     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg101     Document Type: Review
Times cited : (31)

References (38)
  • 1
    • 0033214657 scopus 로고    scopus 로고
    • Application of complementary DNA microarray technology to carcinogen identification, toxicology, and drug-safety evaluation
    • Afshari, C. A., Nuwaysir, E. F., and Barrett, J. C., (1999). Application of complementary DNA microarray technology to carcinogen identification, toxicology, and drug-safety evaluation. Cancer Res. 59, 4759-4760.
    • (1999) Cancer Res. , vol.59 , pp. 4759-4760
    • Afshari, C.A.1    Nuwaysir, E.F.2    Barrett, J.C.3
  • 2
    • 0033608466 scopus 로고    scopus 로고
    • Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
    • Aithal, G., Day, C., Kesteven, P., and Daly, A. (1999). Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications. Lancet 353, 717-719.
    • (1999) Lancet , vol.353 , pp. 717-719
    • Aithal, G.1    Day, C.2    Kesteven, P.3    Daly, A.4
  • 5
    • 0036890399 scopus 로고    scopus 로고
    • The cytochrome p450 superfamily: Biochemistry, evolution, and drug metabolism in humans
    • Danielson, P. B. (2002). The cytochrome p450 superfamily: Biochemistry, evolution, and drug metabolism in humans. Curr. Drug Metab. 3, 561-597.
    • (2002) Curr. Drug Metab. , vol.3 , pp. 561-597
    • Danielson, P.B.1
  • 6
    • 0032808416 scopus 로고    scopus 로고
    • Concise review: Gene expression applied to toxicology
    • Farr, S., and Dunn, R. T., II (1999). Concise review: Gene expression applied to toxicology. Toxicol. Sci. 50, 1-9.
    • (1999) Toxicol. Sci. , vol.50 , pp. 1-9
    • Farr, S.1    Dunn R.T. II2
  • 7
    • 0036696731 scopus 로고    scopus 로고
    • Classifying toxicity and pathology by gene-expression profile - Taking a lead from studies in neoplasia
    • Gant, T. W. (2002). Classifying toxicity and pathology by gene-expression profile - taking a lead from studies in neoplasia. Trends Pharm. Sci. 23, 388-393.
    • (2002) Trends Pharm. Sci. , vol.23 , pp. 388-393
    • Gant, T.W.1
  • 11
    • 0034764359 scopus 로고    scopus 로고
    • Catalog of 46 single nucleotide polymorphisms (SNPs) in the microsomal glutathione S-transferase 1 (MGST1) gene
    • Iida, A., Saito, S., Sekine, A., Harigae, S., Osawa, S., Mishima, C., Kondo, K., Kitamura, Y., and Nakamura, Y. (2001). Catalog of 46 single nucleotide polymorphisms (SNPs) in the microsomal glutathione S-transferase 1 (MGST1) gene. J. Hum. Genet. 46, 590-594.
    • (2001) J. Hum. Genet. , vol.46 , pp. 590-594
    • Iida, A.1    Saito, S.2    Sekine, A.3    Harigae, S.4    Osawa, S.5    Mishima, C.6    Kondo, K.7    Kitamura, Y.8    Nakamura, Y.9
  • 12
    • 0032793249 scopus 로고    scopus 로고
    • Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment
    • Ingelman-Sundberg, M., Oscarson, M., and McLellan, R. A. (1999). Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment. Trends Pharmacol. Sci. 20, 342-349.
    • (1999) Trends Pharmacol. Sci. , vol.20 , pp. 342-349
    • Ingelman-Sundberg, M.1    Oscarson, M.2    McLellan, R.A.3
  • 13
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
    • Johansson, I., Lundqvist, E., Bertilsson, L., Dahl, M. L., Sjoqvist, F., and Ingelman-Sundberg, M. (1993). Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc. Natl. Acad. Sci. U.S.A. 90, 11825-11829.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3    Dahl, M.L.4    Sjoqvist, F.5    Ingelman-Sundberg, M.6
  • 14
    • 12244300909 scopus 로고    scopus 로고
    • Interleukin-10 gene-promoter region polymorphism is associated with eosinophil count and circulating immunoglobulin E in adult asthma
    • Karjalainen, J., Hulkkonen, J., Nieminen, M. M., Huhtala, H., Aromaa, A., Klaukka, T., and Hurme, M. (2003). Interleukin-10 gene-promoter region polymorphism is associated with eosinophil count and circulating immunoglobulin E in adult asthma. Clin. Exp. Allergy 33, 78-83.
    • (2003) Clin. Exp. Allergy , vol.33 , pp. 78-83
    • Karjalainen, J.1    Hulkkonen, J.2    Nieminen, M.M.3    Huhtala, H.4    Aromaa, A.5    Klaukka, T.6    Hurme, M.7
  • 15
    • 0003979578 scopus 로고    scopus 로고
    • 2nd ed. (Oxford monographs on medical genetics, 44). Oxford University Press, Oxford, UK
    • King, R. A., Rotter, J. I., and Motulsky, A. G. (2002). The Genetic Basis of Common Diseases, 2nd ed. (Oxford monographs on medical genetics, 44). Oxford University Press, Oxford, UK.
    • (2002) The Genetic Basis of Common Diseases
    • King, R.A.1    Rotter, J.I.2    Motulsky, A.G.3
  • 16
  • 17
    • 0032533647 scopus 로고    scopus 로고
    • A 4-Mb high-density, single nucleotide polymorphism-based map around human APOE
    • Lai, E., Riley, J., Purvis, I., and Roses, A. (1998). A 4-Mb high-density, single nucleotide polymorphism-based map around human APOE. Genomics 54, 31-38.
    • (1998) Genomics , vol.54 , pp. 31-38
    • Lai, E.1    Riley, J.2    Purvis, I.3    Roses, A.4
  • 18
    • 0037006623 scopus 로고    scopus 로고
    • Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
    • Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A. M., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., et al. (2002). Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet 359, 727-732.
    • (2002) Lancet , vol.359 , pp. 727-732
    • Mallal, S.1    Nolan, D.2    Witt, C.3    Masel, G.4    Martin, A.M.5    Moore, C.6    Sayer, D.7    Castley, A.8    Mamotte, C.9    Maxwell, D.10
  • 19
    • 0030860004 scopus 로고    scopus 로고
    • Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: Characterization of 48 mutations and 53 alleles, their frequencies and evolution
    • Marez, D., Legrand, M., Sabbagh, N., Guidice, J. M., Spire, C., Lafitte, J. J., Meyer, U. A., and Broly, F. (1997). Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: Characterization of 48 mutations and 53 alleles, their frequencies and evolution. Pharmacogenetics 7, 193-202.
    • (1997) Pharmacogenetics , vol.7 , pp. 193-202
    • Marez, D.1    Legrand, M.2    Sabbagh, N.3    Guidice, J.M.4    Spire, C.5    Lafitte, J.J.6    Meyer, U.A.7    Broly, F.8
  • 20
    • 0032748555 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics: Why is this relevant to the clinical geneticist?
    • Nebert, D. W. (1999). Pharmacogenetics and pharmacogenomics: Why is this relevant to the clinical geneticist? Clin. Genet. 56, 247-258.
    • (1999) Clin. Genet. , vol.56 , pp. 247-258
    • Nebert, D.W.1
  • 21
    • 0037068964 scopus 로고    scopus 로고
    • Clinical importance of the cytochromes P450
    • Nebert, D. W., and Russell, D. W. (2002). Clinical importance of the cytochromes P450. Lancet 360, 1155-1162.
    • (2002) Lancet , vol.360 , pp. 1155-1162
    • Nebert, D.W.1    Russell, D.W.2
  • 22
    • 0033199227 scopus 로고    scopus 로고
    • Cytochrome P450 and the individuality of species
    • Nelson, D. R. (1999). Cytochrome P450 and the individuality of species. Arch. Biochem. Biophys. 369, 1-10.
    • (1999) Arch. Biochem. Biophys. , vol.369 , pp. 1-10
    • Nelson, D.R.1
  • 24
    • 0035152815 scopus 로고    scopus 로고
    • Toxicogenomics: Theoretical and practical considerations
    • Orphanides, G., Pennie, W. D., Moffat, G. J., and Kimber, I. (2001). Toxicogenomics: Theoretical and practical considerations. Comm. Tax. 7, 333-346.
    • (2001) Comm. Tax. , vol.7 , pp. 333-346
    • Orphanides, G.1    Pennie, W.D.2    Moffat, G.J.3    Kimber, I.4
  • 25
    • 0035977883 scopus 로고    scopus 로고
    • Toxicogenetics in drug development
    • Park, B. K., and Pirmohamed, M. (2001). Toxicogenetics in drug development. Toxicol. Lett. 120, 281-291.
    • (2001) Toxicol. Lett. , vol.120 , pp. 281-291
    • Park, B.K.1    Pirmohamed, M.2
  • 26
    • 0033625042 scopus 로고    scopus 로고
    • The principles and practice of toxicogenomics: Applications and opportunities
    • Pennie, W. D., Tugwood, J. D., Oliver, G. J. A., and Kimber, I. (2000). The principles and practice of toxicogenomics: Applications and opportunities. Toxicol. Sci. 54, 277-283.
    • (2000) Toxicol. Sci. , vol.54 , pp. 277-283
    • Pennie, W.D.1    Tugwood, J.D.2    Oliver, G.J.A.3    Kimber, I.4
  • 27
    • 0033125120 scopus 로고    scopus 로고
    • The adverse effects of drugs
    • Pirmohamed, M., and Park, B. K. (1999). The adverse effects of drugs. Hosp. Med. 60, 348-352.
    • (1999) Hosp. Med. , vol.60 , pp. 348-352
    • Pirmohamed, M.1    Park, B.K.2
  • 29
    • 0030005627 scopus 로고    scopus 로고
    • Apolipoprotein E alleles as risk factors in Alzheimer's disease
    • Roses, A. D. (1996). Apolipoprotein E alleles as risk factors in Alzheimer's disease. Annu. Rev. Med. 47, 387-400.
    • (1996) Annu. Rev. Med. , vol.47 , pp. 387-400
    • Roses, A.D.1
  • 30
    • 0034660560 scopus 로고    scopus 로고
    • Pharmacogenetics and the practice of medicine
    • Roses, A. D. (2000). Pharmacogenetics and the practice of medicine. Nature 405, 857-865.
    • (2000) Nature , vol.405 , pp. 857-865
    • Roses, A.D.1
  • 31
    • 0036633359 scopus 로고    scopus 로고
    • Genome-based pharmacogenetics and the pharmaceutical industry
    • Roses, A. D. (2002). Genome-based pharmacogenetics and the pharmaceutical industry. Nat. Rev. Drug Discov. 1, 541-549.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 541-549
    • Roses, A.D.1
  • 32
    • 0036783335 scopus 로고    scopus 로고
    • Pharmacogenomics, regulation, and signaling pathways of phases I and II drug metabolizing enzymes
    • Rushmore, T. H., and Kong, A. N. (2002). Pharmacogenomics, regulation, and signaling pathways of phases I and II drug metabolizing enzymes. Curr. Drug Metab. 3, 481-490.
    • (2002) Curr. Drug Metab. , vol.3 , pp. 481-490
    • Rushmore, T.H.1    Kong, A.N.2
  • 35
    • 0034283762 scopus 로고    scopus 로고
    • Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment
    • Taube, J., Halsall, D., and Baglin, T. (2000). Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment. Blood 96, 1816-1819.
    • (2000) Blood , vol.96 , pp. 1816-1819
    • Taube, J.1    Halsall, D.2    Baglin, T.3
  • 36
    • 0036043671 scopus 로고    scopus 로고
    • Toxicogenomics and drug discovery: Will new technologies help us produce better drugs?
    • Ulrich, R., and Friend, S. H. (2002). Toxicogenomics and drug discovery: Will new technologies help us produce better drugs? Nat. Rev. Drug Disc. 1, 84-88
    • (2002) Nat. Rev. Drug Disc. , vol.1 , pp. 84-88
    • Ulrich, R.1    Friend, S.H.2
  • 37
    • 0034621009 scopus 로고    scopus 로고
    • Science, medicine, and the future: Pharmacogenetics
    • Wolf, C. R., Smith, G., and Smith, R. L. (2000). Science, medicine, and the future: Pharmacogenetics. Br. Med. J. 320, 987-990.
    • (2000) Br. Med. J. , vol.320 , pp. 987-990
    • Wolf, C.R.1    Smith, G.2    Smith, R.L.3


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