In vitro correction of cystic fibrosis epithelial cell lines by small fragment homologous replacement (SFHR) technique

BMC Medical Genetics

Volumn 3, Issue , 2002, Pages

  Sangiuolo, Federica ^a   Bruscia, Emanuela ^a,b   Serafino, Annalucia ^c   Nardone, Anna Maria ^d   Bonifazi, Emanuela ^a   Lais, Monica ^a   Gruenert, Dieter C ^b   Novelli, Giuseppe ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^c CNR   (Italy)

^d TOR VERGATA UNIVERSITY HOSPITAL   (Italy)

Author keywords

Cystic fibrosis transmembrane conductance regulator (CFTR); Gene targeting; Gene therapy; Transfection; Transmission electron microscopy (TEM)

Indexed keywords

CATION; DNA; DNA FRAGMENT; LIPID; LIPOSOME; RNA; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; CELL CULTURE; CELL IMMORTALIZATION; CELL LINE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYSTIC FIBROSIS; DNA VECTOR; DRUG EFFICACY; ENDOCYTOSIS; EPITHELIUM CELL; GENE MUTATION; GENE REPLACEMENT THERAPY; GENE SEQUENCE; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MAMMAL CELL; MEMBRANE FUSION; NONVIRAL GENE DELIVERY SYSTEM; POLYMERASE CHAIN REACTION; RESPIRATORY EPITHELIUM; SEQUENCE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; WILD TYPE;

MAMMALIA;

EID: 0042368424     PISSN: 14712350     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2350-3-8     Document Type: Article

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