메뉴 건너뛰기




Volumn 3, Issue 10, 1996, Pages 859-867

Gene targeting of CFTR DNA in CF epithelial cells

Author keywords

Gene therapy; Homologous replacement; Small DNA fragments

Indexed keywords

CHLORIDE ION; COMPLEMENTARY DNA; DNA; MESSENGER RNA; TRANSMEMBRANE CONDUCTANCE REGULATOR;

EID: 0029959582     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (93)

References (42)
  • 1
    • 0024424270 scopus 로고
    • Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
    • Riordan JR et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 1989; 245: 1066-1073.
    • (1989) Science , vol.245 , pp. 1066-1073
    • Riordan, J.R.1
  • 2
    • 0024453308 scopus 로고
    • Identification of the cystic fibrosis gene: Chromosome walking and jumping
    • Rommens JM et al. Identification of the cystic fibrosis gene: chromosome walking and jumping. Science 1989; 245: 1059-1065.
    • (1989) Science , vol.245 , pp. 1059-1065
    • Rommens, J.M.1
  • 3
    • 0025133518 scopus 로고
    • Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic fibrosis gene
    • Kerem BS et al. Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic fibrosis gene. Pror Naff Acad Sci USA 1990; 87: 8447-8451.
    • (1990) Pror Naff Acad Sci USA , vol.87 , pp. 8447-8451
    • Kerem, B.S.1
  • 4
    • 0024423668 scopus 로고
    • Identification of the cystic fibrosis gene: Genetic analysis
    • Kerem B et al. Identification of the cystic fibrosis gene: genetic analysis. Science 1989; 245, 1073-1080.
    • (1989) Science , vol.245 , pp. 1073-1080
    • Kerem, B.1
  • 5
    • 0025155528 scopus 로고
    • Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells
    • Rich DP et al Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells. Nature 1990; 347: 358-363.
    • (1990) Nature , vol.347 , pp. 358-363
    • Rich, D.P.1
  • 6
    • 0025094612 scopus 로고
    • Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer
    • Drumm ML et al. Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer. Cell 1990; 62: 1227-1233.
    • (1990) Cell , vol.62 , pp. 1227-1233
    • Drumm, M.L.1
  • 7
    • 0026687233 scopus 로고
    • Correction of defective PKA regulation of outwardly rectifying chloride channels by insertion of cystic fibrosis transmembrane regulator into CF airway epithelial cells
    • Egan M et al. Correction of defective PKA regulation of outwardly rectifying chloride channels by insertion of cystic fibrosis transmembrane regulator into CF airway epithelial cells. Nature 1992; 358: 581-584.
    • (1992) Nature , vol.358 , pp. 581-584
    • Egan, M.1
  • 8
    • 0026558496 scopus 로고
    • In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium
    • Rosenfeld MA et al. In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium. Cell 1992; 68: 143-155.
    • (1992) Cell , vol.68 , pp. 143-155
    • Rosenfeld, M.A.1
  • 9
    • 0029100239 scopus 로고
    • A controlled study of adenoviral vectormediated gene transfer in the nasal epithelium of patients with cystic fibrosis
    • Knowles MR et al A controlled study of adenoviral vectormediated gene transfer in the nasal epithelium of patients with cystic fibrosis. New Engl J Med 1995; 333: 823-831.
    • (1995) New Engl J Med , vol.333 , pp. 823-831
    • Knowles, M.R.1
  • 10
    • 0028168641 scopus 로고
    • Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis
    • Crystal RG et al. Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet 1994; 8: 42-51.
    • (1994) Nat Genet , vol.8 , pp. 42-51
    • Crystal, R.G.1
  • 11
    • 0027933841 scopus 로고
    • Gene therapy of cystic fibrosis lung disease using El deleted adenoviruses: A phase I trial
    • Wilson JM et al. Gene therapy of cystic fibrosis lung disease using El deleted adenoviruses: a phase I trial. Hum Gene Ther 1994; 5: 501-519.
    • (1994) Hum Gene Ther , vol.5 , pp. 501-519
    • Wilson, J.M.1
  • 12
    • 0027377523 scopus 로고
    • Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis
    • Zabner J et al. Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell 1993; 75: 207-216.
    • (1993) Cell , vol.75 , pp. 207-216
    • Zabner, J.1
  • 13
    • 0028913411 scopus 로고
    • Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
    • Caplen NJ et al. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nat Med 1995; 1: 39-46.
    • (1995) Nat Med , vol.1 , pp. 39-46
    • Caplen, N.J.1
  • 14
    • 0026917078 scopus 로고
    • Gene expression from adeno-associated virus vectors in airway epithelial cells
    • Flotte TR et al. Gene expression from adeno-associated virus vectors in airway epithelial cells. Am J Resp Cell Mol Biol 1992; 7, 349-356.
    • (1992) Am J Resp Cell Mol Biol , vol.7 , pp. 349-356
    • Flotte, T.R.1
  • 15
    • 0028328261 scopus 로고
    • Cellular immunity to viral antigens limits El-deleted adenoviruses for gene therapy
    • Yang Y et al. Cellular immunity to viral antigens limits El-deleted adenoviruses for gene therapy. Prof Natl Acad Sci USA 1994; 91: 4407-4411.
    • (1994) Prof Natl Acad Sci USA , vol.91 , pp. 4407-4411
    • Yang, Y.1
  • 16
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Yang Y, Li Q, Ertl HCJ, Wilson JM. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J Virol 1995; 69: 2004-2015.
    • (1995) J Virol , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.J.3    Wilson, J.M.4
  • 17
    • 0030039896 scopus 로고    scopus 로고
    • Biosynthetic and growth abnormalities are associated with high level expression of CFTR in heterologous cells
    • Schiavi SC et al. Biosynthetic and growth abnormalities are associated with high level expression of CFTR in heterologous cells. Am J Physiol 1996; 270: C341-C351.
    • (1996) Am J Physiol , vol.270
    • Schiavi, S.C.1
  • 18
    • 10244271430 scopus 로고
    • Evidence for toxic effects of overexpression of CFTR in vitro and in vivo
    • Abstr
    • Schiavi SC et al. Evidence for toxic effects of overexpression of CFTR in vitro and in vivo Pediatr Pulmonol 1993; 9 (Suppl): 30A (Abstr).
    • (1993) Pediatr Pulmonol , vol.9 , Issue.SUPPL.
    • Schiavi, S.C.1
  • 19
    • 0028878052 scopus 로고
    • Gene therapy in a xenograft model of cystic fibrosis lung corrects chloride transport more effectively than the sodium defect
    • Goldman MJ, Yang Y, Wilson JM. Gene therapy in a xenograft model of cystic fibrosis lung corrects chloride transport more effectively than the sodium defect. Nat Genet 1995; 9: 126-131.
    • (1995) Nat Genet , vol.9 , pp. 126-131
    • Goldman, M.J.1    Yang, Y.2    Wilson, J.M.3
  • 20
    • 0029892249 scopus 로고    scopus 로고
    • Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA-DNA oligonucleotide
    • Yoon K, Cole-Strauss A, Kmiec EB. Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA-DNA oligonucleotide. Proc Natl Acad Sci USA 1996; 93: 2071-2076.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2071-2076
    • Yoon, K.1    Cole-Strauss, A.2    Kmiec, E.B.3
  • 21
    • 0024769286 scopus 로고
    • Homologous recombination involving small single-stranded oligonucleotides in human cells
    • Campbell CR et al. Homologous recombination involving small single-stranded oligonucleotides in human cells. NOT Biol 1989; 1: 223-227.
    • (1989) NOT Biol , vol.1 , pp. 223-227
    • Campbell, C.R.1
  • 22
    • 0029133392 scopus 로고
    • Gene targeting with a replication-defective adenovirus vector
    • Fujita A et al. Gene targeting with a replication-defective adenovirus vector. J Virol 1995; 69: 6180-6190.
    • (1995) J Virol , vol.69 , pp. 6180-6190
    • Fujita, A.1
  • 23
    • 0026349985 scopus 로고
    • Selective cleavage of human DNA: RecA assisted restriction endonuclease (RARE) cleavage
    • Ferrin LJ, Camerini-Otero RD. Selective cleavage of human DNA: recA assisted restriction endonuclease (RARE) cleavage. Science 1991; 254: 1494-1497.
    • (1991) Science , vol.254 , pp. 1494-1497
    • Ferrin, L.J.1    Camerini-Otero, R.D.2
  • 24
    • 0025189913 scopus 로고
    • Short DNA fragments induce site specific recombination in mammalian cells
    • Hunger-Bertling K, Harrer P, Bertling W. Short DNA fragments induce site specific recombination in mammalian cells. Mol Cell Biochem 1990; 92: 107-116.
    • (1990) Mol Cell Biochem , vol.92 , pp. 107-116
    • Hunger-Bertling, K.1    Harrer, P.2    Bertling, W.3
  • 25
    • 0025312204 scopus 로고
    • Targeted gene modification for gene therapy of stem cells
    • Boggs SS. Targeted gene modification for gene therapy of stem cells. Int J Cell Clon 1990; 8: 80-96.
    • (1990) Int J Cell Clon , vol.8 , pp. 80-96
    • Boggs, S.S.1
  • 26
    • 0024328536 scopus 로고
    • Altering the genome by homologous recombination
    • Capecchi MR. Altering the genome by homologous recombination. Science 1989; 224: 1288-1292.
    • (1989) Science , vol.224 , pp. 1288-1292
    • Capecchi, M.R.1
  • 27
    • 0027351450 scopus 로고
    • Polyamidoamine cascade polymers and their use for efficient transfection of cells in culture
    • Haensler J, Szoka FC. Polyamidoamine cascade polymers and their use for efficient transfection of cells in culture. Biaconj Chem 1993; 4: 85-93.
    • (1993) Biaconj Chem , vol.4 , pp. 85-93
    • Haensler, J.1    Szoka, F.C.2
  • 28
    • 0027399966 scopus 로고
    • Cyclic amphipathic peptide-DNA complexes mediate high efficiency transfection of adherent mammalian cells
    • Legendre J-Y, Szoka FC. Cyclic amphipathic peptide-DNA complexes mediate high efficiency transfection of adherent mammalian cells. Proc Natl Acad Sci USA 1993; 90: 893-897.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 893-897
    • Legendre, J.-Y.1    Szoka, F.C.2
  • 29
    • 0026918861 scopus 로고
    • Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis
    • Johnson LG et al. Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis. Nat Genet 1992; 2: 21-25.
    • (1992) Nat Genet , vol.2 , pp. 21-25
    • Johnson, L.G.1
  • 30
    • 0027597730 scopus 로고
    • An immortalized cystic fibrosis tracheal epithelial cell line homozygous for the ΔAF508 CFTR mutation
    • Kunzelmann K et al. An immortalized cystic fibrosis tracheal epithelial cell line homozygous for the ΔAF508 CFTR mutation. Am J Resp Cell Mol Biol 1993; 8: 522-529.
    • (1993) Am J Resp Cell Mol Biol , vol.8 , pp. 522-529
    • Kunzelmann, K.1
  • 31
    • 0029093192 scopus 로고
    • Epithelial cell specific properties and genetic complementation in a AF508 cystic fibrosis nasal polyp cell line
    • Kunzelmann K et al Epithelial cell specific properties and genetic complementation in a AF508 cystic fibrosis nasal polyp cell line In Vitro Cell Dev Biol 1995; 31: 617-624.
    • (1995) In Vitro Cell Dev Biol , vol.31 , pp. 617-624
    • Kunzelmann, K.1
  • 32
    • 0025337617 scopus 로고
    • A cystic fibrosis pancreatic adenocarcinoma cell line
    • Schoumacher RA et al. A cystic fibrosis pancreatic adenocarcinoma cell line. Proc Natl Acad Sci USA 1990; 87: 4012-4016.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4012-4016
    • Schoumacher, R.A.1
  • 33
    • 0027928745 scopus 로고
    • CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells
    • Cozens AL et al. CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am J Resp Cell Mol Biol 1994; 10: 38-47.
    • (1994) Am J Resp Cell Mol Biol , vol.10 , pp. 38-47
    • Cozens, A.L.1
  • 34
    • 0025760318 scopus 로고
    • Genomic DNA sequence of the cystic fibrosis transmembrane conductance regulator (CFTR) gene
    • Zielenski J et al. Genomic DNA sequence of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Genomics 1991; 10: 214-228.
    • (1991) Genomics , vol.10 , pp. 214-228
    • Zielenski, J.1
  • 35
    • 0030030567 scopus 로고    scopus 로고
    • Human CFTR sequences in regions flanking exon 10: A simple repeat sequence polymorphism in intron 9
    • Xu Z, Gruenert DC. Human CFTR sequences in regions flanking exon 10: a simple repeat sequence polymorphism in intron 9. Biochem Biophys Res Commun 1996; 219: 140-145.
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 140-145
    • Xu, Z.1    Gruenert, D.C.2
  • 36
    • 0027533930 scopus 로고
    • Targeting in linear DNA duplexes with two complementary probe strands for hybrid stability
    • Sena EP, Zarling DA. Targeting in linear DNA duplexes with two complementary probe strands for hybrid stability. Nat Genet 1993; 3: 365-371.
    • (1993) Nat Genet , vol.3 , pp. 365-371
    • Sena, E.P.1    Zarling, D.A.2
  • 37
    • 0023811731 scopus 로고
    • Use of psoralen-modified oligonucleotides to trap three-stranded rec A-DNA complexes and repair of these crosslinked complexes by ABC exonuclease
    • Cheng S et al. Use of psoralen-modified oligonucleotides to trap three-stranded rec A-DNA complexes and repair of these crosslinked complexes by ABC exonuclease. J Biol Chem 1988; 263: 15110-15117.
    • (1988) J Biol Chem , vol.263 , pp. 15110-15117
    • Cheng, S.1
  • 39
    • 0026724465 scopus 로고
    • Characterization of immortal cystic fibrosis tracheobronchial gland epithelial cells
    • Cozens AL et al. Characterization of immortal cystic fibrosis tracheobronchial gland epithelial cells. Proc Natl Acad Sci USA 1992; 89: 5171-5175.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5171-5175
    • Cozens, A.L.1
  • 41
    • 0026059035 scopus 로고
    • Direct and crossover PCR amplification to facilitate Tn5supF-based sequencing of lambda phage clones
    • Krishnan BR et al. Direct and crossover PCR amplification to facilitate Tn5supF-based sequencing of lambda phage clones. Nucleic Acids Res 1991; 19: 6177-6182.
    • (1991) Nucleic Acids Res , vol.19 , pp. 6177-6182
    • Krishnan, B.R.1
  • 42
    • 0025346025 scopus 로고
    • Long-term culture of normal and cystic fibrosis epithelial cells grown under serumfree conditions
    • Gruenert DC, Basbaum CB, Widdicombe JH. Long-term culture of normal and cystic fibrosis epithelial cells grown under serumfree conditions.In Vitro Cell Dev Biol 1990; 26: 411-418.
    • (1990) In Vitro Cell Dev Biol , vol.26 , pp. 411-418
    • Gruenert, D.C.1    Basbaum, C.B.2    Widdicombe, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.