Role of zinc-finger proteins Sp1 and zif268/egr-1 in transcriptional regulation of the human synaptobrevin II gene

European Journal of Biochemistry

Volumn 239, Issue 3, 1996, Pages 827-834

  Petersohn, Dirk ^a   Thiel, Gerald ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

SP1; Synapsin I; Synaptobrevin II; zif268 egr 1

Indexed keywords

SYNAPTOBREVIN; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CHO CELL; CONTROLLED STUDY; EXPRESSION VECTOR; GENE CONSTRUCT; GENE EXPRESSION; HUMAN; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; REPORTER GENE; SYNAPSE VESICLE; TRANSCRIPTION REGULATION;

ANIMALIA; ESCHERICHIA COLI; FELIS CATUS; MAMMALIA;

EID: 0029902142     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.0827u.x     Document Type: Article

References (42)

1. Ackerman, S. L., Minden, A. G., Williams, G. T., Bobonis, C. & Yeung, C.-Y. (1991) Functional significance of an overlapping binding motif for Sp1 and zif268 in the murine adenosine deaminase gene promoter, Proc. Natl Acad. Sci. USA 88, 7523-7527.
2. Archer, B. T. III, Özcelik, T., Jahn, R., Francke, U. & Südhof, T. C. (1990) Structure and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2, J. Biol. Chem. 265, 17267-17273.
3. Cao, X., Koski, R. A., Gashler, A., McKieran, M., Morris, C. F., Gaffney, R., Hay, R. V. & Sukhatme, V. P. (1990) Identification and characterization of the egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals, Mol. Cell. Biol. 10, 1931-1939.
4. Cao, X., Mahendran, R., Guy, G. R. & Tan, Y. H. (1993) Detection and characterization of cellular egr-1 binding to its recognition site, J. Biol. Chem. 268, 16949-16957.
5. Carey, M., Lin, Y.-S., Green, M. R. & Ptashne, M. (1990) A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives, Nature 345, 361-364.
6. Christy, B., Lau, L. F. & Nathans, D. (1988) A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences, Proc. Natl Acad. Sci. USA 85, 7857-7861.
7. Christy, B. & Nathans, D. (1989) DNA binding site of the growth factor-inducible protein zif268, Proc. Natl Acad. Sci. USA 86, 8737-8741.
8. Cibelli, G., Schoch, S., Pajunk, H., Brand, I. A. & Thiel, G. (1996) A (G+C)-rich motif in the aldolase C promoter functions as a constitutive transcriptional enhancer element, Eur. J. Biochem. 237, 311-317.
9. Cole, A. J., Saffen, D. W., Baraban, J. M. & Worley, P. F. (1989) Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation, Nature 340, 474-476.
10. Cornwell, M. M. & Smith, D. E. (1993) Sp1 activates the MDRI promoter through one of two distinct G-rich regions that modulate promoter activity, J. Biol. Chem. 268, 19505-19511.
11. Courey, A. J., Holtzman, D. A., Jackson, S. P. & Tjian, R. (1989) Synergistic activation by the glutamine-rich domains of human transcription factor Sp1, Cell 59, 827-836.
12. Courey, A. J. & Tjian, R. (1988) Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif, Cell 55, 887-898.
13. Courey, A. J. & Tjian, R. (1992) Mechanisms of transcriptional control as revealed by studies of human transcription factor Sp1, in Transcriptional regulation (McKnight, S. L. & Yamamoto, K. R., eds), pp. 743-769, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
14. Driever, W. & Nüsslein-Vollhard, C. (1989) The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo, Nature 337, 138-143.
15. Ebert, S. & Wong, D. L. (1995) Differential activation of the rat phenylethanolamine N-methyltransferase gene by Sp1 and Egr-1, J. Biol. Chem. 270, 17299-17305.
16. Jones, K. A. & Tjian, R. (1985) Sp1 binds to promoter sequences and activates herpes simplex virus 'immediate-early' gene transcription in vitro, Nature 317, 179-182.
17. Khachigian, L. M., Williams, A. J. & Collins, T. (1995) Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor A-chain promoter in cultured vascular endothelial cells, J. Biol. Chem. 270, 27679-27686.
18. Kriwacki, R. W., Schultz, S. C., Steitz, T. A. & Caradonna, J. P. (1992) Sequence-specific recognition of DNA by zinc-finger peptides derived from the transcription factor Sp1, Proc. Natl Acad. Sci. USA 89, 9759-9763.
19. Lemaire, P., Revelant, O., Bravo, R. & Charnay, P. (1988) Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells, Proc. Natl Acad. Sci. USA 85, 4691-4695.
20. Lemaire, P., Vesque, C., Schmitt, J., Stunnenberg, H., Frank, R. & Charney, P. (1990) The serum-inducible mouse gene Krox-24 encodes a sequence-specific transcriptional activator, Mol. Cell. Biol. 7, 3456-3467.
21. Link, E., Edelman, L., Chou, J. H., Binz, T., Yamasaki, S., Eisel, U., Baumert, M., Südhof, T. C., Niemann, H. & Jahn, R. (1992) Tetanus toxin action: Inhibition of neurotransmitter release linked to synaptobrevin proteolysis, Biochem. Biophys. Res. Commun. 189, 1017-1023.
22. Lynch, M. A., Voss, K. L., Rodriguez, J. & Bliss, T. V. P. (1994) Increase in synaptic vesicle proteins accompanies long-term potentiation in the dentate gyrus, Neuroscience 60, 1-5.
23. McGeoch, D. J., Dolon, A., Donald, S. & Brauer, D. H. (1986) Complete DNA sequence of the short repeat region in the genome of herpes simplex virus type 1, Nucleic Acids Res. 14, 1727-1745.
24. Milbrandt, J. (1987) A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor, Science 238, 797-799.
25. Mizushima, S. & Nagata, S. (1990) pEF-BOS, a powerful mammalian expression vector, Nucleic Acids Res. 18, 5322.
26. Petersohn, D., Schoch, S., Brinkmann, D. R. & Thiel, G. (1995) The human synapsin II gene promoter: possible role for the transcription factors zif268/egr-1, polyoma enhancer activator 3 and AP2, J. Biol. Chem. 270, 24361-24369.
27. Rosetto, O., Gorza, L., Schiavo, G., Schiavo, N., Scheller, R. H. & Montecucco, C. (1996) Vamp/synaptobrevin isoforms 1 and 2 are widely and differentially expressed in nonneuronal tissues, J. Cell Biol. 132, 167-179.
28. Saffen, D. W., Cole, A. J., Worley, P. F., Christy, B. A., Ryder, K. & Baraban, J. M. (1988) Convulsant-induced increase in transcription factor messenger RNAs in rat brain, Proc. Natl Acad. Sci. USA 85, 7795-7799.
29. Sánchez, I., Hughes, R. T., Mayer, B. J., Yee, K., Woodgett, J. R., Avruch, J., Kyriakis, J. M. & Zon, L. I. (1994) Role of SAPK/ERK kinase-1 in the stresS-activated pathway regulating transcription factor c-jun, Nature 372, 794-798.
30. Schiavo, G., Benfenati, F., Poulain, B., Rossetto, O., Polverino de Laurato, P., DasGupta, B. & Montecucco, C. (1992) Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin-2, Nature 359, 832-835.
31. Sheng, M. & Greenberg, M. E. (1990) The regulation and function of c-fos and other immediate early genes in the nervous system, Neuron 4, 477-485.
32. Shingu, T. & Bornstein, P. (1994) Overlapping Egr-1 and Sp1 sites function in the regulation of transcription of the mouse thrombospondin 1 gene, J. Biol. Chem. 269, 32551-32557.
33. Skerka, C., Decker, E. L. & Zipfel, P. F. (1995) A regulatory element in the human intcrleukin 2 gene promoter is abinding site for the zinc finger proteins Sp1 and EGR-1, J. Biol. Chem. 270, 22500-22506.
34. Söllner, T., Whiteheart, S. W., Brunner, M., Erdjument-Bromage, H., Geromanos, S., Tempest, P. & Rothman, J. (1993) SNAP receptors implicated in vesicle targeting and fusion, Nature 362, 318-324.
35. Südhof, T. C. (1990) The structure of the human synapsin I gene and protein, J. Biol. Chem. 265, 7849-7852.
36. Sukhatme, V. P., Cao, X., Chang, L. C., Tsai-Morris, C.-H., Stamenkovich, D., Ferreira, P. C. P., Cohen, D. R., Edwards, S. A., Shows, T. B., Curran, T., Le Beau, M. M. & Adamson, E. D. (1988) A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization, Cell 53, 37-43.
37. Thiel, G. (1995) Recent breakthroughs in neurotransmitter release: Paradigm for regulated exocytosis? News Physiol. Sci 10, 42-46.
38. Thiel, G., Greengard, P. & Südhof, T. C. (1991) Characterization of tissue-specific transcription by the human synapsin I gene promoter, Proc. Natl Acad. Sci. USA 88, 3431-3435.
39. Thiel, G., Petersohn, D. & Schoch, S. (1996) pHIVTATA-CAT, a versatile vector to study transcriptional regulatory elements in mammalian cells, Gene (Amst.) 168, 173-176.
40. Thiel, G., Schoch, S. & Petersohn, D. (1994) Regulation of synapsin I gene expression by the zinc finger transcription factor zip 268/egr-1, J. Biol. Chem. 269, 15294-15301.
41. Tsai-Morris, C. H., Cao, X. & Sukhatme, V. P. (1988) 5′-flanking sequence and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene, Nucleic Acids Res. 16, 8835-8846.
42. Wisden, W., Errington, M. L., Williams, S., Dunnett, S. B., Waters, C., Hitchcock, D., Evan, G., Bliss, T. V. P. & Hunt, S. P. (1990) Differential expression of immediate early genes in the hippocampus and spinal cord, Neuron 4, 603-614.