Evidence that TRPC1 (transient receptor potential canonical 1) forms a Ca2+-permeable channel linked to the regulation of cell volume in liver cells obtained using small interfering RNA targeted against TRPC1

Biochemical Journal

Volumn 373, Issue 2, 2003, Pages 327-336

  Chen, Jinglong ^a   Barritt, Greg J ^a  

^a FLINDERS UNIVERSITY   (Australia)

Author keywords

ATP; Hypotonicity; Maitotoxin; Thapsigargin

Indexed keywords

CELLS; POSITIVE IONS; RNA;

INTRACELLULAR MESSENGER;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATE; CATION CHANNEL; MAITOTOXIN; PROTEIN; RNA; SMALL INTERFERING RNA; THAPSIGARGIN; TRPC1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CELL VOLUME; ENDOPLASMIC RETICULUM; LIVER CELL; METABOLIC REGULATION; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN TARGETING; RAT; TARGET CELL;

ANIMALS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CALCIUM; CALCIUM CHANNELS; CARCINOMA, HEPATOCELLULAR; CELL SIZE; DNA, COMPLEMENTARY; ENZYME INHIBITORS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; ION CHANNELS; LIVER; MANGANESE; POLYMERASE CHAIN REACTION; PRECIPITIN TESTS; RATS; RNA, MESSENGER; RNA, SMALL INTERFERING; THAPSIGARGIN; TRANSFECTION; TRPC CATION CHANNELS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0042344924     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021904     Document Type: Article

References (52)

1. Barritt, G. J. (2000) Calcium signalling in liver cells. In Calcium: the Molecular Basis of Calcium Action in Biology and Medicine (Pochet, R., Donato, R., Haiech, J., Heizmann, C. and Gerlce, V., eds.), pp. 175-196, Kluwer Academic Publishers, The Netherlands
2. Haussinger, D. and Lang, F. (1991) Cell volume in the regulation of hepatic function: a mechanism for metabolic control. Biochim. Biophys. Acta 1071, 331-350
3. Dunkelberg, J. C., Feranchak, A. P. and Fitz, J. G. (2001) Liver cell volume regulation: size matters. Hepatology 33, 1349-1352
4. Graf, J. and Haussinger, D. (1996) Ion transport in hepatocytes: mechanisms and correlations to cell volume, hormone actions and metabolism. J. Hepatol. 24, 53-77
5. Striggow, F. and Bohnensack, R. (1994) Inositol 1,4,5-trisphosphate activates receptor-mediated calcium entry by two different pathways in hepatocytes. Eur. J. Biochem. 222, 229-234
6. 2+ inflow system using lanthanide ions. Biochim. Biophys. Acta 1268, 97-106
7. Bear, C. E. and Li, C. H. (1991) Calcium-permeable channels in rat hepatoma cells are activated by extracellular nucleotides. Am. J. Physiol. 261, C1018-C1024
8. Woods, N. M., Dixon, C. J., Yasumoto, T., Cuthbertson, K. S. R. and Cobbold, P. H. (1999) Maitotoxin-induced free Ca changes in single rat hepatocytes. Cell. Signalling 11, 805-811
9. Brereton, H. M., Chen, J. L., Rychkov, G., Harland, M. L. and Barritt, G. J. (2001) Maitotoxin activates an endogenous non-selective cation channel and is an effective initiator of the activation of the heterologously expressed hTRPC1 (transient receptor potential) non-selective cation channel in H4-IIE liver cells. Biochim. Biophys. Acta 1540, 107-126
10. 2+ identified by patch-clamp recording in rat liver cells. Hepatology 33, 938-947
11. Roe, M. W., Moore, A. L. and Lidofsky, S. D. (2001) Purinergic-independent calcium signaling mediates recovery from hepatocellular swelling: implications for volume regulation. J. Biol. Chem. 276, 30871-30877
12. Zitt, C., Halaszovich, C. R. and Luckhoff, A. (2002) The TRP family of cation channels: probing and advancing the concepts on receptor-activated calcium entry. Prog. Neurobiol. 66, 243-264
13. Vennekens, R., Voets, T., Bindels, R. J., Droogmans, G. and Nilius, B. (2002) Current understanding of mammalian TRP homologues. Cell Calcium 31, 253-264
14. Minke, B. and Cook, B. (2002) TRP channel proteins and signal transduction. Physiol. Rev. 82, 429-472
15. Hayes, P., Meadows, H. J., Gunthorpe, M. J., Harries, M. H., Duckworth, D. M., Cairns, W., Harrison, D. C., Clarke, C. E., Ellington, K., Prinjha, R. K. et al. (2000) Cloning and functional expression of a human orthologue of rat vanilloid receptor-1. Pain 88, 205-215
16. Wissenbach, U., Bodding, M., Freichel, M. and Flockerzi, V. (2000) Trp12, a novel Trp related protein from kidney. FEBS Lett. 485, 127-134
17. Peng, J. B., Chen, X. Z., Berger, U. V., Weremowicz, S., Morton, C. C., Vassilev, P. M., Brown, E. M. and Hediger, M. A. (2000) Human calcium transport protein CaT1. Biochem. Biophys. Res. Commun. 278, 326-332
18. 2+-activated nonselective cation channel mediating cell membrane depolarization. Cell 109, 397-407
19. Montell, C., Birnbaumer, L. and Flockerzi, V. (2002) The TRP channels, a remarkably functional family. Cell 108, 595-598
20. Runnels, L. W., Yue, L. and Clapham, D. E. (2001) TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science 291, 1043-1047
21. Sinkins, W. G., Estacion, M. and Schilling, W. P. (1998) Functional expression of Trpc1 a human homologue of the Drosophila Trp channel. Biochem. J. 331, 331-339
22. Antoniotti, S., Lovisolo, D., Pla, A. F. and Munaron, L. (2002) Expression and functional role of bTRPC1 channels in native endothelial cells. FEBS Lett. 510, 189-195
23. Engelke, M., Friedrich, O., Budde, P., Schafer, C., Niemann, U., Zitt, C., Jungling, E., Rocks, O., Luckhoff, A. and Frey, J. (2002) Structural domains required for channel function of the mouse transient receptor potential protein homologue TRP1beta. FEBS Lett. 523, 193-199
24. Singh, B. B., Zheng, C., Liu, X., Lockwich, T., Liao, D., Zhu, M. X., Birnbaumer, L. and Ambudkar, I. S. (2001) Trp1-dependent enhancement of salivary gland fluid secretion: role of store-operated calcium entry. FASEB J. 15, 1652-1664
25. 2+ entry pathway. FASEB J. 15, 1727-1738
26. 2+ release from endoplasmic reticulum in B lymphocytes. J. Exp. Med. 195, 673-681
27. Elbashir, S. M., Harborth, J., Weber, K. and Tuschl, T. (2002) Analysis of gene function in somatic mammarian cells using small interfering RNAs. Methods (Duluth) 26, 199-213
28. Hannon, G. J. (2002) RNA interference. Nature (London) 418, 244-251
29. Holen, T., Amarzguioui, M., Wiiger, M. T., Babaie, E. and Prydz, H. (2002) Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids. Res. 30, 1757-1766
30. Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K. and Tuschl, T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (London) 411, 494-498
31. 2+ channel antagonists and, in contrast to freshly isolated hepatocytes, does not require a pertussis toxin-sensitive trimeric GTP-binding protein. Biochim. Biophys. Acta 1497, 11-26
32. Ong, H. L., Chen, J., Chataway, T., Brereton, H., Zhang, L., Downs, T., Tsiokas, L. and Barritt, G. (2002) Specific detection of the endogenous transient receptor potential (TRP)-1 protein in liver and airway smooth muscle cells using immunoprecipitation and Western-blot analysis. Biochem. J. 364, 641-648
33. Tuschl, T. and Borkhardt, A. (2002) Small interfering RNAs. Mol. Interventions 2, 158-167
34. Tsiokas, L., Arnould, T., Zhu, C. W., Kim, E., Walz, G. and Sukhatme, V. P. (1999) Specific association of the gene product of PKD2 with the TRPC1 channel. Proc. Natl. Acad. Sci. U.S.A. 96, 3934-3939
35. Bradford, H. F. and Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Adv. Exp. Med. Biol. 69, 395-404
36. 2+ channels, in rat hepatocytes. Biochem. J. 363, 117-126
37. - currents. Am. J. Physiol. 271, G239-G248
38. Roman, R. M., Wang, Y., Lidofsky, S. D., Feranchak, A. P., Lomri, N., Scharschmidt, B. F. and Fitz, J G. (1997) Hepatocellular ATP-binding cassette protein expression enhances ATP release and autocrine regulation of cell volume. J. Biol. Chem. 272, 21970-21976
39. Feranchak, A. P., Fitz, J. G. and Roman, R. M. (2000) Volume-sensitive purinergic signaling in human hepatocytes. J. Hepatol. 33, 174-182
40. Hohjoh, H. (2002) RNA interference (RNAi) induction with various types of synthetic oligonucieotide duplexes in cultured human cells. FEBS Lett. 521, 195-199
41. Martinez, J., Patkaniowska, A., Urlaub, H., Luhrmann, R. and Tuschl, T. (2002) Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110, 563-574
42. Schwarz, D. S. Hutvagner, G., Haley, B. and Zamore, P. D. (2002) Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol. Cell 10, 537-548
43. Hamada, M., Ohtsuka, T., Kawaida, R., Koizumi, M., Morita, K., Furukawa, H., Imanishi, T., Miyagishi, M. and Taira, K. (2002) Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3′-ends of siRNAs. Antisense Nucleic Acid Drug Dev. 12, 301-309
44. 2+- sensitive cation channels. J. Biol. Chem. 275, 27 799-27 805
45. Strubing, C., Krapivinsky, G., Krapivinsky, L. and Clapham, D. E. (2001) TRPC1 and TRPC5 form a novel cation channel in mammalian brain. Neuron 29, 645-655
46. Kanzaki, M., Zhang, Y. Q., Mashima, H., Li, L., Shibata, H. and Kojima, I. (1999) Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I. Nat. Cell Biol. 1, 165-170
47. Ma, D., Zerangue, N., Lin, Y. F., Collins, A., Yu, M., Jan, Y. N. and Jan, L. Y. (2001) Role of ER export signals in controlling surface potassium channel numbers. Science 291, 316-319
48. Hassock, S. R., Zhu, M. X., Trost, C., Flockerzi, V. and Authi, K. S. (2002) Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the store-independent calcium entry channel. Blood 100, 2801-2811
49. 2+ in hypotonically activated osmolyte efflux from a rat hepatoma cell line. J. Biol. Chem. 277, 40324-40334
50. Nilius, B. (2003) Calcium-impermeable monovalent cation channels: a TRP connection? Br. J. Pharmacol. 138, 5-7
51. Lockwich, T. P., Liu, X., Singh, B. B., Jadlowiec, J., Weiland, S. and Ambudkar, I. S. (2000) Assembly of Trp1 in a signaling complex associated with caveolin-scaffolding lipid raft domains. J. Biol. Chem. 275, 11 934-11 942
52. Papakonstanti, E. A., Vardaki, E. A. and Stournaras, C. (2000) Actin cytoskeleton: a signalling sensor in cell volume regulation. Cell. Physiol. Biochem. 10, 257-264