Cyclin D1 expression in the intestinal mucosa and tumors of Apc1638N mice

Anticancer Research

Volumn 23, Issue 3 B, 2003, Pages 2217-2226

  Shinozaki, Hiroharu ^a   Yang, Kan ^a,e   Fan, Kunhua ^a   Edelmann, Winfried ^b   Kucherlapati, Raju ^c   Bernard Weinstein, I ^d   Lipkin, Martin ^a  

^a STRANG CANCER PREVENTION CENTER   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^e ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Apc1638N mice; Colonic cancer; Cyclin D1

Indexed keywords

BIOLOGICAL MARKER; CYCLIN D1;

ADENOMATOUS POLYP; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER INVASION; CANCER STAGING; CELL GRANULE; CELLULAR DISTRIBUTION; CHEMOPROPHYLAXIS; COLORECTAL CANCER; CONTROLLED STUDY; DIAGNOSTIC VALUE; DIETARY INTAKE; DISEASE ASSOCIATION; DUODENUM; FEMALE; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA; MALE; MOUSE; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH;

ADENOMATOUS POLYPOSIS COLI; ANIMALS; COLON; CYCLIN D1; DIET; DUODENUM; EPITHELIAL CELLS; FEMALE; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MALE; MICE;

EID: 0042307261     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Fearon ER and Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 61: 759-767, 1990.
2. Gorden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Albertsen H, Joslyn G, Stevens J, Spirio L, Robertson M, Sargeant L, Krapcho K, Wolff E, Burt R, Hughes JP, Warrington J, McPherson J, Wasmuth J, LePaslier D, Abderrahim H, Cohen D, Leppert M and White R: Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66: 589-600, 1991.
3. Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, Koyama K, Utsunomiya J, Baba S, Hedge P, Markham A, Krush AJ, Petersen G, Hamilton SR, Nilbert MC, Levy DB. Bryan TM, Preisinger AC, Smith KJ, Su L-K, Kinzler KW and Vogelstein B: Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science (Washington DC) 253: 665-669, 1991.
4. Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, Vogelstein B and Kinzler KW: APC mutations occur early during colorectal tumorigenesis. Nature (Lond.) 359: 235-237, 1992.
5. Miyoshi Y, Nagase H, Ando H, Horii A, Ichii S, Nakatsuru S, Aoki T, Miki Y, Mori T and Nakamura Y: Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum Mol Genet 1: 229-233, 1992.
6. Taso J and Shibata D: Further evidence that one of the earliest alterations in colorectal carcinogenesis involves APC. Am J Pathol 145: 531-534, 1994.
7. Moser AR, Pitot HC and Dove WF: A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science (Washington DC) 247: 322-324, 1990.
8. Oshima M, Oshima H, Kitagawa K, Kobayashi M, Itakura C and Taketo M: Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc Natl Acad Sci U.S.A. 92: 4482-4486, 1995.
9. Fodde R, Edelmann W, Yang K, Leeuwen CV, Carlson C, Renault B, Breukel C, Alt E, Lipkin M, Khan PM and Kucherlapati, R: A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc Natl Acad Sci U.S.A. 91: 8969-8973, 1994.
10. Yang K, Edelmann W, Fan K, Lau K, Kolli VR, Fodde R, Khan PM, Kucherlapati R and Lipkin M: A mouse model of human familial adenomatous polyposis. J Exp Zool 277: 245-254, 1997.
11. Smits R, Kartheuser A, Jagmohan-Changur S, Leblanc V, Breukel C, de Vries A, van Kranen H, van Krieken JH, Williamson S, Edelmann W, Kucherlapati R, Khan PM and Fodde R: Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis. Carcinogenesis 18: 321-327, 1997.
12. Weinstein IB and Zhou P: Cell cycle control gene defects and human cancer. In: J. R. Bertino (ed.), Encyclopedia of Cancer, Vol.1, pp. 256-267, New York: Academic Press, 1997.
13. Motokura T and Arnold A: Cyclin D and oncogenesis. Curr Opin Genet Dev 3: 5-10, 1993.
14. Hunter T and Pines J: Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. Cell 79: 573-582, 1994.
15. Hartwell LH and Kastan MB: Cell cycle control and cancer. Science (Washington DC) 266: 1821-1828, 1994.
16. Sherr CJ: D-type cyclins. Trends Biochem Sci 20: 187-190, 1995.
17. Sherr CJ: Cancer cell cycles. Science (Washington DC) 274: 1672-1677, 1996.
18. Donnellan R and Chetty R: Cyclin D1 and human neoplasia. J Clin Patho Mol Pathol 51: 1-7, 1998.
19. Sutter T, Doi S, Carnevale KA, Arber N and Weinstein I: B. Expression of cyclins D1 and E in human colon adenocarcinomas. J Med 28: 285-309, 1997.
20. Arber N, Hibshoosh H, Moss SF, Sutter T, Zhang Y, Begg M, Wang S, Weinstein IB and Holt PR: Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis. Gastroenterology 110: 669-674, 1996.
21. Zhang T, Nanney LB, Luongo C, Lamps L, Heppner KJ, DuBois RN and Beauchamp RD: Concurrent overexpression of cyclin D1 and cyclin-dependent kinase 4 (Cdk4) in intestinal adenomas from multiple intestinal neoplasia (Min) mice and human familial adenomatous polyposis patients. Cancer Res 57: 169-175, 1997.
22. Ciaparrone M, Yamamoto H, Yao Y, Sgambato A, Cattoretti G, Tomita N, Monden T, Rotterdam H and Weinstein IB: Localization and expression of p27KIP1 in multistage colorectal carcinogenesis. Cancer Res 58: 114-122, 1998.
23. Bartkova J, Lukas J, Strauss M and Bartek J: The PRAD1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas. Int J Cancer 58: 568-573, 1994.
24. Bartkova J, Lukas J, Strauss M and Bartek J: Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis. Oncogene 10: 775-778, 1995.
25. Wang Q-S, Papanikolaou A, Sabourin CL K and Rosenberg DW: Altered expression of cyclin D1 and cyclin-dependent kinase 4 in azoxymethane-induced mouse colon tumorigenesis. Carcinogenesis 19: 2001-2006, 1998.
26. Arber N, Doki Y, Han E K-H, Sgambato A, Zhou P, Kim NH, Delohery T, Klein MG, Holt PR and Weinstein IB: Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells. Cancer Res 57: 1569-1574, 1997.
27. Yang K, Edelmann W, Fan K, Lau K, Leung D, Newmark H, Kucherlapati R and Lipkin M: Dietary modulation of carcinoma development in a mouse model for human familial adenomatous polyposis. Cancer Res 58: 5713-5717, 1998.
28. Report of the American Institute of Nutrition ad hoc Committee on standards for nutrition studies. J Nutr 107: 1340-1348, 1977.
29. Newmark HL, Lipkin M and Maheshwari N: Colonic hyperplasia and hyperproliferation induced by a nutritional stress diet with four components of Western-style diet. J Natl Cancer Inst 82: 491-496, 1990.
30. Newmark HL, Lipkin M and Maheshwari N: Colonic hyperproliferation induced in rats and mice by nutritional-stress diets containing four components of a human Western-style diet (series 2). Am J Clin Nutr 54: 2095-2145, 1991.
31. Risio M, Lipkin M, Newmark H, Yang K, Rossini FP, Steele VE, Boone CW and Kelloff G: Apoptosis, cell replication and Western-style diet-induced tumorigenesis in mouse colon. Cancer Res 56: 4910-4916, 1996.
32. Jass JR and Sobin LH: Histological Typing of Intestinal Tumours. Second Edition. World Health Organization, Springer-Verlag, Berlin, Heidelberg, New York, London, Paris, Tokyo, Hong Kong. 1989.
33. Lukas J, Pagano M, Staskova Z, Draetta G and Bartek J: Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumor cell lines, Oncogene 9: 707-718, 1994.
34. Palmqvist R, Stenling R, Oberg A and Landberg G: Expression of cyclin D1 and retinoblastoma protein in colorectal cancer. Eur J Cancer 34: 1575-1581, 1998.
35. Betticher DC, Heighway J, Hasleton PS, Altermatt HJ, Ryder WD J, Cerny T and Thatcher N: Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small-cell lung cancer. Br J Cancer 73: 294-300, 1996.
36. Nakamura S, Seto M, Bannno S, Suzuki S, Koshikawa T, Kitoh K, Kagami Y, Ogura M, Yatabe Y and Kojima M: Immunohistochemical analysis of cyclin D1 protein in hematopoietic neoplasms with specific reference to mantel cell lymphoma. Jpn J Cancer Res 85: 1270-1279, 1994.
37. Lukas J, Bartokova J, Welcker M, Peterson OW, Peters G, Strauss M and Bartek J: Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types. Oncogene 10: 2125-2134, 1995.
38. Matsushime H, Roussel MF, Ashmunm RA and Sherr CJ: Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell 65: 701-713, 1991.
39. Diehl JA and Sherr CJ: A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase. Mol Cell Biol 17: 7362-7374, 1997.
40. Weinstein IB and Zhou P: Cell cycle control gene defects and human cancer. In: Bertino, J.R. (ed.), Encyclopedia of Cancer, Academic Press, New York, Vol 1, pp. 256-267, 1997.
41. Filmus J, Robles AI, Shi W, Wong MJ, Colombo LL and Conti CJ: Induction of cyclin D1 overexpression by activated ras. Oncogene 9: 3627-3633, 1994.
42. Arber N, Sutter T, Miyake M, Kahn SM, Venkatraj VS, Sobrino A, Warburton D, Holt PR and Weinstein IB: Increased expression of cyclin D1 and the RB tumor suppresser gene in ck-ras transformed rat enterocytes. Oncogene 12: 1903-1908, 1996.
43. Winston JT, Coats SR, Wang Y-Z and Pledger WJ: Regulation of the cell cycle machinery by oncogenic ras. Oncogene 12: 127-134, 1996.
44. Aktas H, Cai H and Cooper GM: Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27kip1. Mol Cell Biol 66: 3850-3857, 1997.
45. Baeg G-H, Mastumine A, Kuroda T, Bhattacharjee RN, Miyashiro I, Toyoshima K and Akiyama T: The tumor suppresser gene product APC blocks cell cycle progression from G0/G1 to S phase. EMBO J 14: 5618-5625, 1995.
46. Tetsu O and McCormick F: Beta-catenin regulates cyclin D1 expression in colon carcinoma cells. Nature (Lond.) 398: 422-426, 1999.
47. Hunter T: Oncoprotein networks. Cell 88: 333-346, 1997.
48. Korinek V, Barker N, Morin P, van Wichen D, de Weger R, Kinzler KW, Vogelstein B and Clevers H: Constitutive transcriptional activation by a β-catenin-Tcf complex in APC-/colon carcinoma. Science 275: 1784-1787, 1997.
49. Morin JP, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B and Kinzler KW: Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science 275: 1787-1790, 1997.